Abstract：
BACKGROUND:Among the oral potentially malignant disorders, leukoplakia stands out as the most prevalent. The purpose of this study was to analyse the clinical-pathological features of oral leukoplakia in groups of patients from three major pathology centers in two different regions of Brazil, in order to determine which factors would be associated to the clinical risk of malignant transformation. MATERIAL AND METHODS:A total of 148 patients was analyzed, and data regarding gender, age, site, classification of the clinical subtype, harmful habits such as use of tobacco and alcohol, time of evolution and presence of dysplasia were collected. The association between risk factors and malignant transformation was investigated using the chi-square test and Fischer's exact test for correlation of variables. A significance level of 5% (p≤0.05) was used. RESULTS:The mean age of the patients was 60 years, and 56% were female. Most of the lesions (34,5%) were located in the lateral and ventral regions of the tongue. Of the 148 patients, ninety had clinical follow-up. Malignant transformation occurred in 13 patients (8.8%), with an average of 44 months of follow up. CONCLUSIONS:Non-smoker, nonhomogeneous clinical presentation, location at the tongue, and the presence of high degree of dysplasia were statistically relevant factors associated with a higher risk of transformation transformation.
journal_name
Med Oral Patol Oral Cir Bucaljournal_title
Medicina oral, patologia oral y cirugia bucalauthors
Cerqueira JM,Pontes FS,Santos-Silva AR,Almeida OP,Costa RF,Fonseca FP,Gomez RS,Neto NC,Miyahara LA,Rodrigues-Fernandes CI,Neto ED,Araújo ALdoi
10.4317/medoral.24175subject
Has Abstractpub_date
2020-11-28 00:00:00eissn
1698-4447issn
1698-6946pii
24175pub_type
杂志文章abstract：BACKGROUND:The aim of this study is to describe the presence, to reveal the frequency and characteristics of accessory canals (ACs) of the canalis sinuosus (CS) by cone beam computed tomography (CBCT). MATERIAL AND METHODS:A total of 326 CBCT examinations were scanned retrospectively. The anatomical views were evaluat...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：10.4317/medoral.23235
更新日期：2020-01-01 00:00:00
abstract：UNLABELLED:One of the most commonly used mandibular anesthesia techniques is the Spix technique, which is very useful in clinical practice, but is risky when the patient is a bearer of blood dyscrasias. OBJECTIVE:The aim of this study was to present an alternative to the Spix technique in order to achieve troncular an...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：
更新日期：2008-01-01 00:00:00
abstract：:Pycnodysostosis is a rare clinical entity, first described in 1962 by Maroteaux and Lamy. It is a genetic disorder, usually diagnosed at an early age. However, the diagnosis is sometimes late, made as a result of bone fracture, given the severe bone fragility resulting from increased bone density. Oral and maxillofaci...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章,评审
doi：
更新日期：2008-10-01 00:00:00
abstract：:The evaluation of bone regeneration and peri-implantary bone apposition requires laboratory techniques that allow the evaluation of hard tissues without needing to decalcify them. In this study, we describe the cutting-grinding procedure (EXAKT system) for obtaining samples of undecalcified bone and aim to establish t...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章,评审
doi：
更新日期：2005-04-01 00:00:00
abstract：OBJECTIVE:A systematic review is made to determine whether human immunodeficiency virus (HIV) infection has an impact upon dental implant osseointegration. STUDY DESIGN:A PubMed (MEDLINE) literature search was made of articles published up until 14 April 2014. The systematic review was conducted based on the Preferred...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章,评审
doi：10.4317/medoral.20408
更新日期：2015-05-01 00:00:00
abstract：BACKGROUND:Evaluation of the efficacy and safety of a mandibular advancement device (MAD) (KlearwayTM) in the treatment of mild-to-moderate obstructive sleep apnea and chronic roncopathy. MATERIAL AND METHODS:A randomized, placebo-controlled, double blinded, and crossover clinical trial was conducted. Placebo device (...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章,随机对照试验
doi：10.4317/medoral.20649
更新日期：2015-09-01 00:00:00
abstract：OBJECTIVES:A study was made of the effect of nonsurgical periodontal treatment upon blood glucose control in type 2 diabetics with periodontal disease. STUDY DESIGN:A pre-post repeated measures analytical design was used, with a PubMed search of the related articles published up until December 2008. RESULTS:The impro...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：10.4317/medoral.15.e808
更新日期：2010-09-01 00:00:00
abstract：AIM:To compare the apical sealing in mesio-buccal canals of extracted molars obturated with low-temperature thermoplasticized gutta-percha or cold lateral condensation techniques using a .06 or a .02 mm/mm tapered gutta-percha master cone. The secondary aim was to evaluate the depth of spreader penetration in root cana...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2007-03-01 00:00:00
abstract：OBJECTIVE:To study nanostructural dentinal changes produced by endodontic irrigants. STUDY DESIGN:Experimental study. Nanoindentations were performed on peritubular (PD) and intertubular dentine (ID) with an atomic force microscopy. Stiffness and adhesion force were determined before and after application of 5.25% sod...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：10.4317/medoral.18713
更新日期：2013-07-01 00:00:00
abstract：:Based on a few case reports of oral mucosal diseases a number of questions is raised about the role of dentists-general practitioners in the diagnostic procedure and management of patients with such diseases. For instance, are dentists prepared to prescribe topical corticosteroids and should dentists be taught how and...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：10.4317/medoral.24465
更新日期：2021-01-04 00:00:00
abstract：BACKGROUND:The aim of the present prospective clinical study is to compare the stability of the implant-bone interface by the ISQ quotient and marginal bone loss (MBL) rate during one year of follow-up in four system implants with the same surface and different design. MATERIAL AND METHODS:Prospective randomized clini...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章,随机对照试验
doi：10.4317/medoral.22742
更新日期：2019-03-01 00:00:00
abstract：OBJECTIVES:To evaluate the prevalence of dental agenesis and its possible association with other developmental dental anomalies and systemic entities. SETTING AND SAMPLE POPULATION:Descriptive transversal study, for which 1518 clinical records, of patients visited by the Odontological Service of the Primary Health Cen...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：10.4317/medoral.15.e569
更新日期：2010-07-01 00:00:00
abstract：OBJECTIVES:Multifocal epithelial hyperplasia (MEH) is benign, asymptomatic oral disease with viral etiology. The frequency of this disease varies widely from one geographic region to another, and can vary, from 0.002 to 35% depending on the population studied. STUDY DESIGN:Here we report the clinicopathological featur...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：10.4317/medoral.15.e591
更新日期：2010-07-01 00:00:00
abstract：OBJECTIVE:The purpose of the present study was to investigate the expression of the α2-integrin subunit and heat shock protein 47 (Hsp47) in two families with isolated gingival fibromatosis (GF) form and one family with GF associated with dental abnormalities and normal gingival (NG). STUDY DESIGN:Immunohistochemistry...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：10.4317/medoral.17970
更新日期：2013-01-01 00:00:00
abstract：OBJECTIVES:Several medical and dental schools have described their experience in the transition from conventional to digital microscopy in the teaching of general pathology and histology disciplines; however, this transitional process has scarcely been reported in the teaching of oral pathology. Therefore, the objectiv...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：10.4317/medoral.19863
更新日期：2015-01-01 00:00:00
abstract：:Worldwide, the use of cocaine has an increased over the years, various secondary effects have been described. Here we present a 48 years old female with a 2-month evolution bucconasal ulcer in the hard palate induced by cocaine usage accompanied by swallow and phonation dysfunctions. Ethiopathogenesis, differential di...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：
更新日期：2006-05-01 00:00:00
abstract：OBJECTIVE:To assess the microbiological effects of an antiseptic, non-alcohol based mouth-rinse containing chlorhexidine and cetylpyridinium chloride, in patients undergoing radiation therapy for head-and-neck cancer. STUDY DESIGN:This was a parallel, double-blind, prospective, randomized clinical trial, including pat...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2011-11-01 00:00:00
abstract：:Sarcoidosis is a multisystemic granulomatous disease of unknown aetiology that usually presents with bilateral hiliar adenopathies, pulmonary infiltrations, and ocular and cutaneous lesions. The specific cutaneous lesions, or granulomatous, are produced in from 9% to 37% of patients with systemic sarcoidosis. Neverthe...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：
更新日期：2010-05-01 00:00:00
abstract：:Angioleiomyoma is an uncommon benign soft tissue tumor usually found in the lower extremities and rarely observed in oral tissues. It is microscopically characterized as a proliferation of smooth muscle cells intermingled with abundant vascular channels. Oral angioleiomyomas affect mostly the lips, palate, buccal muco...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章,评审
doi：10.4317/medoral.16.e482
更新日期：2011-07-01 00:00:00
abstract：BACKGROUND:It is now well established that IL-4 has a central role in the development of monocytes to multinucleated giant cells (MGCs) by inducing the expression of integrins on the surface of monocytes. The aim of this study was to investigate the potential role of IL-4 in induction of β5 integrin expression in the p...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：10.4317/medoral.20935
更新日期：2017-01-01 00:00:00
abstract：BACKGROUND:Osteonecrosis of the jaw (ONJ) is a destructive bone process in patients undergoing bisphosphonate therapy and it is modulated by local and systemic factors. The purpose of this article is to determine the prevalence of ONJ in patients who have undergone intravenous bisphosphonate therapy, and relate the ris...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：10.4317/medoral.20092
更新日期：2015-05-01 00:00:00
abstract：OBJECTIVES:The aim of this report is to present the results of a scanning electron microscopic study on the presence of matrix vesicles (MVs) found in human dentine. STUDY DESIGN:Dentin tissue from 20 human bicuspids was analyzed by means of scanning electron microscopy. RESULTS:MVs were found as outgrowths of the ce...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：10.4317/medoral.18650
更新日期：2013-05-01 00:00:00
abstract：BACKGROUND:Lichen sclerosus is a mucocutaneous autoimmune disease which might be initiated by infectious pathogens as Borrelia Bugrdorferi and HPV. This disease shows destructive potential and is rarely diagnosed in oral mucosa. The purpose of this paper is to evaluate the characteristics of cases described in literatu...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章,评审
doi：10.4317/medoral.21606
更新日期：2017-07-01 00:00:00
abstract：BACKGROUND:The aim of this study was to evaluate and compare the postoperative effect of a topic gel containing chlorhexidine, chitosan, allantoine and dexpanthenol versus a placebo for pain and inflammation control after third molar surgery. MATERIAL AND METHODS:A gel combining 0.2% chlorhexdine, 0.5% chitosan, 5% de...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章,随机对照试验
doi：10.4317/medoral.23661
更新日期：2020-09-01 00:00:00
abstract：OBJECTIVE:To evaluate the effectiveness in the formation of resin tags, adhesive lateral branches and hybrid layers of five adhesive systems, when bonding to dentine. MATERIAL AND METHODS:Flat dentin surfaces from 25 molars were bonded with several adhesive systems according to the manufacturers' instructions. Composi...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：10.4317/medoral.15.e112
更新日期：2010-01-01 00:00:00
abstract：BACKGROUND:Extensive literature exists about the use of the BFP in the treatment of oral defects but, to our knowledge, no article refers to the use of the BFP as a substitute of the membrane barriers for treatment of peri-implant bone defects. The aim was to evaluate the use of the buccal fat pad as a coating material...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：10.4317/medoral.20212
更新日期：2015-11-01 00:00:00
abstract：OBJECTIVES:The objective was to analyze the impact of preventive programmes on oral quality of life in school students aged 11-12 yrs. STUDY DESIGN:In the school year 1996/97, a quasi-experimental study was initiated in Granada province with four groups of students aged 6-7 yrs: Sealant + Fluoride (sealants on first p...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：
更新日期：2007-09-01 00:00:00
abstract：BACKGROUND:The Franciscan Hospital for Children Oral Health-Related Quality of Life questionnaire (FHC-OHRQOL-Q) is an instrument designed specifically for parents and caregivers of patients with special needs that has not yet been applied in Spain. The aim of this study was to adapt it to Spanish and evaluate its reli...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：10.4317/medoral.22553
更新日期：2018-09-01 00:00:00
abstract：BACKGROUND:This study aimed to identify (1) the predilection site of postoperative infection after third molar extraction surgery, (2) risk factors associated with postoperative infection, and (3) the cause of the difference between delayed- and early-onset infections. MATERIALS AND METHODS:This retrospective study in...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：10.4317/medoral.22556
更新日期：2019-01-01 00:00:00
abstract：:Denture hyperplasia is a reactive lesion of the oral mucosa, usually associated to an ill-fitting denture. This lesion is easily diagnosed and in some cases distinct microscopic variations such as osseous, oncocytic and squamous metaplasia may be found. These metaplastic alterations probably are associated with the ly...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：
更新日期：2005-07-01 00:00:00
