Abstract：
OBJECTIVE:To assess the microbiological effects of an antiseptic, non-alcohol based mouth-rinse containing chlorhexidine and cetylpyridinium chloride, in patients undergoing radiation therapy for head-and-neck cancer. STUDY DESIGN:This was a parallel, double-blind, prospective, randomized clinical trial, including patients irradiated as part of the therapy of head-and-neck cancer, aged 18-75, with at least 10 teeth, and willing to sign an informed consent. Cancer patients were randomly assigned to one of the two treatments (test mouth-rinse or a placebo). Three visits were scheduled (baseline, 14 and 28 days). Microbiological findings were evaluated in tongue, mucosa and subgingival samples, by means of culture. Microbiological variables were assessed by means of the Mann-Whitney, Wilcoxon and chi-square tests. RESULTS:70 patients were screened and 36 were included. The detection of Candida species in mucosa and tongue samples showed significant reductions in the test group. Total bacterial counts decreased in both groups from baseline to the 2-week visit, while minor changes occurred between 2 and 4 weeks (effects on P. gingivalis, P. intermedia, C. rectus, E. corrodens). CONCLUSIONS:Within the limitations of the small sample size, this study suggests that the use of the tested mouth-rinse may lead to improvements in microbiological parameters in patients irradiated for head-and-neck cancer.
journal_name
Med Oral Patol Oral Cir Bucaljournal_title
Medicina oral, patologia oral y cirugia bucalauthors
Lanzós I,Herrera D,Santos S,O'Connor A,Peña C,Lanzós E,Sanz Msubject
Has Abstractpub_date
2011-11-01 00:00:00pages
e1036-42issue
7eissn
1698-4447issn
1698-6946pii
17234journal_volume
16pub_type
杂志文章,随机对照试验abstract：BACKGROUND:A single-blinded randomized controlled trial among patients requiring an upper third molar extraction was performed to evaluate the anxiety degree after receiving information or not about the functioning of The Wand system. Secondarily, perceived pain and the need of re-anesthesia were assessed. MATERIAL AN...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章,随机对照试验
doi：10.4317/medoral.23315
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journal_title：Medicina oral, patologia oral y cirugia bucal
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更新日期：2017-01-01 00:00:00
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journal_title：Medicina oral, patologia oral y cirugia bucal
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journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：10.4317/medoral.15.e14
更新日期：2010-01-01 00:00:00
abstract：OBJECTIVES:It has been reported that clinical changes due to hypersensitivity reactions to various foods, preservatives, and oral hygiene products may be consistent with the characteristic signs of orofacial granulomatosis (OFG). The objective of this study was to examine 37 well-documented cases of cinnamon-induced co...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
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更新日期：2007-10-01 00:00:00
abstract：BACKGROUND:Bromelain is a cysteine protease isolated from pineapple with a range of biological properties including platelet aggregation inhibition and anti-inflammatory effects. Recent studies have evaluated the clinical implications of bromelain in reducing postoperative inflammatory complications after third molar s...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章,meta分析
doi：10.4317/medoral.22731
更新日期：2019-01-01 00:00:00
abstract：OBJECTIVE:The purpose of the present study was to investigate the expression of the α2-integrin subunit and heat shock protein 47 (Hsp47) in two families with isolated gingival fibromatosis (GF) form and one family with GF associated with dental abnormalities and normal gingival (NG). STUDY DESIGN:Immunohistochemistry...
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更新日期：2013-01-01 00:00:00
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journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章,评审
doi：
更新日期：2008-10-01 00:00:00
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journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章,随机对照试验
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更新日期：2014-05-01 00:00:00
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journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：
更新日期：2009-02-01 00:00:00
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journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：
更新日期：2009-07-01 00:00:00
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journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章,评审
doi：
更新日期：2007-08-01 00:00:00
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journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
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更新日期：2013-01-01 00:00:00
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pub_type： 杂志文章
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更新日期：2019-09-01 00:00:00
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更新日期：2012-07-01 00:00:00
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journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：
更新日期：2011-09-01 00:00:00
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journal_title：Medicina oral, patologia oral y cirugia bucal
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journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
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更新日期：2011-03-01 00:00:00
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pub_type： 临床试验,杂志文章
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更新日期：2011-01-01 00:00:00
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journal_title：Medicina oral, patologia oral y cirugia bucal
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更新日期：2011-03-01 00:00:00
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journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
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更新日期：2013-01-01 00:00:00
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journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
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更新日期：2011-07-01 00:00:00
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journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
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更新日期：2011-05-01 00:00:00
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journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：
更新日期：2011-07-01 00:00:00
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journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：10.4317/medoral.20491
更新日期：2015-09-01 00:00:00
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journal_title：Medicina oral, patologia oral y cirugia bucal
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更新日期：2005-04-01 00:00:00
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journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：
更新日期：2004-01-01 00:00:00
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pub_type： 杂志文章
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abstract：BACKGROUND:TORS has become one of the latest surgical alternatives in the treatment of oropharynx squamous cell carcinomas (OPSCC) and has become increasingly accepted by surgeons as a treatment option. Surgical robots were designed for various purposes, such as allowing remote telesurgery, and eliminating human factor...
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pub_type： 杂志文章,meta分析
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更新日期：2020-09-01 00:00:00
