Abstract：
BACKGROUND:Cheilitis granulomatosa (CG) is a disturbing and persistent idiopathic lip swelling. The cause and treatment has not been wholly elucidated. Some reports infer that CG is mainly associated with dental infection but no firm or reliable microbiological evidence has been provided for a causative organism. This study aimed to evaluate whether microorganisms contribute to the etiology of CG in order to inform appropriate treatment op tions in clinic. MATERIAL AND METHODS:Unstimulated saliva was collected from 15 CG patients who were diagnosed clinically and pathologically and 15 healthy controls (HC). DNA was extracted from the precipitate of the centrifuged saliva for 16s rRNA high-throughput sequencing using the Miseq PE300 platform. The distribution of the microbiome between the two groups was compared. RESULTS:CG patients had a greater microbial flora that was more diverse than the HC. Prevotella, Alloprevotella, Porphyromonas, Actinomyces, Rothia, Fusobacterium, Haemophilus, and Aggregatibacter had a significantly higher abundance in CG patients. In contrast, Streptococcus and Campylobacter were the most abundant genera in HC with a mean relative abundance of 63% and 2%, respectively. The microbiological network indicated that most of the bacteria that were enriched at greater levels in CG patients were likely to be Prevotella, Actinomyces, and Rothia. These have been shown to co-exist with other bacteria. CONCLUSIONS:The composition and structure of bacterial communities in CG patients were different from HC. Most of the genera observed in CG patients were associated with periodontitis and pulp infection. These findings might be helpful in understanding the etiology of CG. Further study will be needed to confirm these findings and explore the underlying pathological mechanism.
journal_name
Med Oral Patol Oral Cir Bucaljournal_title
Medicina oral, patologia oral y cirugia bucalauthors
Liu Y,Zhang Q,Hu X,Chen F,Hua Hdoi
10.4317/medoral.23041subject
Has Abstractpub_date
2019-11-01 00:00:00pages
e719-e725issue
6eissn
1698-4447issn
1698-6946pii
23041journal_volume
24pub_type
杂志文章abstract：OBJECTIVES:Recent developments of new direct oral anticoagulants that target specific clotting factors necessitate understanding of coagulation biology. The objective of this tutorial is to offer dental professionals a review of coagulation mechanisms and the pharmacodynamics of the conventional and new oral anticoagul...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章,评审
doi：10.4317/medoral.19140
更新日期：2013-05-01 00:00:00
abstract：OBJECTIVES:1. - To measure the alveolar resorption processes that occur in patients wearing mandibular overdentures on 2 implants and fully-removable maxillary dentures, and to evaluate the same process on patients wearing fully-removable dentures on both arches. 2.- To verify whether Kelly's Combination Syndrome occur...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：
更新日期：2009-04-01 00:00:00
abstract：OBJECTIVE:A systematic review is made to determine whether human immunodeficiency virus (HIV) infection has an impact upon dental implant osseointegration. STUDY DESIGN:A PubMed (MEDLINE) literature search was made of articles published up until 14 April 2014. The systematic review was conducted based on the Preferred...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章,评审
doi：10.4317/medoral.20408
更新日期：2015-05-01 00:00:00
abstract：OBJECTIVE:To assess the microbiological effects of an antiseptic, non-alcohol based mouth-rinse containing chlorhexidine and cetylpyridinium chloride, in patients undergoing radiation therapy for head-and-neck cancer. STUDY DESIGN:This was a parallel, double-blind, prospective, randomized clinical trial, including pat...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2011-11-01 00:00:00
abstract：AIM:To assess the prevalence of oral mucosa lesions (OL) in a group of kidney transplant (KT) patients, and analyze possible OL associations with one another and with drugs use and relevant clinical and laboratory variables. METHODOLOGY:Transversal study, in which consecutive KT patients from the nephrology outpatient...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：
更新日期：2005-05-01 00:00:00
abstract：BACKGROUND:Mandibular sagittal split osteotomy (MSSO) may incur unfavorable split and sensorineural injuries. Knowledge of the anatomic location of the mandibular canal (MC) and bone thickness in the region of interest for MSSO, and the possible variations by age and gender can assist in avoiding such complications. Pu...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：10.4317/medoral.22969
更新日期：2019-07-01 00:00:00
abstract：:Merkel cell carcinoma is a rare and aggressive primary cutaneous neoplasm. Clinically it is characterized by innocuous appearance, as a fast growing asymptomatic nodule or plaque. Head and neck are the most common sites of presentation (50%). The treatment is based on local surgery completed with cervical lymph node d...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章,评审
doi：
更新日期：2008-06-01 00:00:00
abstract：:Bisphosphonates is a group of inorganic pyrophosphates analogues that suppress bone resorption by inducing osteoclast inactivation, being frequently used for management of diseases affecting bone metabolism, bone metastases and bone tumors. However, since 2003 many cases describing the presence of necrotic bone exposu...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章,评审
doi：10.4317/medoral.19094
更新日期：2014-03-01 00:00:00
abstract：BACKGROUND:Retrospective studies to assess the distribution of oral diseases (ODs) are helpful in estimating the prevalence of oral diagnoses in the population, and thus help in preventive and curative services. Prevalence and frequency data for ODs are available from many countries, but information from Chile is scarc...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章,评审
doi：10.4317/medoral.21665
更新日期：2017-05-01 00:00:00
abstract：BACKGROUND:The literature does not report any association between habitual snoring and sleep bruxism, but these situations can be a reason for frequent complaints of individuals, impairing the quality of life. This study was performed to investigate the sleep period and amount of habitual snoring in individuals with sl...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：10.4317/medoral.23136
更新日期：2019-11-01 00:00:00
abstract：:Traumatic neuromas are rare entities which characteristically arise subsequently to surgery and are usually accompanied by pain, typically neuralgic. We present an unusual case of an intraosseous traumatic neuroma of the inferior alveolar nerve following tooth extraction. A 56-year-old man consulted for paresthesias a...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：
更新日期：2008-03-01 00:00:00
abstract：OBJECTIVES:To asses whether dental eruption order can play a role in the early diagnosis of crossed laterality. STUDY DESIGN:Dental eruption pattern along with eye, ear, hand and foot lateralism were examined on 131 children between 6 to 8 years old from public schools from a multietnic population area of Barcelona ci...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：10.4317/medoral.19567
更新日期：2014-09-01 00:00:00
abstract：BACKGROUND:Among the oral potentially malignant disorders, leukoplakia stands out as the most prevalent. The purpose of this study was to analyse the clinical-pathological features of oral leukoplakia in groups of patients from three major pathology centers in two different regions of Brazil, in order to determine whic...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：10.4317/medoral.24175
更新日期：2020-11-28 00:00:00
abstract：AIMS:To evaluate the reliability and reproducibility of calculating the Bolton Index using cone-beam computed tomography (CBCT), and to compare this with measurements obtained using the 2D Digital Method. MATERIAL AND METHODS:Traditional study models were obtained from 50 patients, which were then digitized in order t...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：10.4317/medoral.18069
更新日期：2012-09-01 00:00:00
abstract：:Intraoral granulocytic sarcoma is an unusual manifestation of chronic or acute leukemia. The oral manifestations often involve enlargements of the gingival and mucosal tissue from direct leukemic cell infiltration. Only 38 cases have been reported in scientific literature to date. We present the case of a 47 year-old ...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：10.4317/medoral.15.e350
更新日期：2010-03-01 00:00:00
abstract：:Recently there have been reports of osteonecrosis of the jaw (ONJ) in patients with chronic therapy with bisphosphonates (Bps). So far three drugs have been linked: Pamidronate of disodium, Zoledronic acid and Alendronate of sodium. It is due to a non detected side effect in clinical trials before commercialization, a...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：
更新日期：2007-08-01 00:00:00
abstract：:The odontogenic myxoma is a rare entity located in mandible and upper maxilla. Due to its local aggressiveness, wide surgical excision is mandatory. Several surgical techniques have been described for the reconstruction of segmental mandibular defects. In comparison with other free flaps, the vascularized free fibular...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：
更新日期：2006-11-01 00:00:00
abstract：:Liposarcomas represent between 15 and 18% of all sarcomas with the most common site being the extremities and retroperitoneum. Liposarcomas of the head and neck are rare, with an estimated incidence representing 3 to 5.6% of all liposarcomas. Liposarcomas most commonly present in the soft tissues of the neck. Primary ...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：
更新日期：2009-05-01 00:00:00
abstract：BACKGROUND:To investigate the occupational profile, educational level, marital status and deleterious habits to the health of patients with maxillofacial fractures of a population of northeastern Brazil. MATERIAL AND METHODS:A retrospective study of patients records admitted to the Division of Oral and Maxillofacial S...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：10.4317/medoral.21969
更新日期：2018-01-01 00:00:00
abstract：OBJECTIVES:It has been reported that clinical changes due to hypersensitivity reactions to various foods, preservatives, and oral hygiene products may be consistent with the characteristic signs of orofacial granulomatosis (OFG). The objective of this study was to examine 37 well-documented cases of cinnamon-induced co...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：
更新日期：2007-10-01 00:00:00
abstract：:We grouped as oral lichenoid disease (OLD) a series of chronic inflammatory processes with autoimmune base that affect the epithelium of the oral mucosa. This disease presents in 2% of the population with a marked predilection for the female gender, especially perimenopausal women. Clinically, it is characterized by t...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章,评审
doi：
更新日期：2009-03-01 00:00:00
abstract：BACKGROUND:Oropharyngeal mucositis (OM) is one of the main side-effects of oncological therapy. There is no treatment to prevent its occurrence, but some zinc-based therapies have been proven to help in decreasing its intensity. The objective of this study was to determine the effect of zinc in OM in children with acut...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：10.4317/medoral.23798
更新日期：2020-11-01 00:00:00
abstract：OBJECTIVE:To study nanostructural dentinal changes produced by endodontic irrigants. STUDY DESIGN:Experimental study. Nanoindentations were performed on peritubular (PD) and intertubular dentine (ID) with an atomic force microscopy. Stiffness and adhesion force were determined before and after application of 5.25% sod...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：10.4317/medoral.18713
更新日期：2013-07-01 00:00:00
abstract：PURPOSE:Chlorhexidine is a good prophylactic agent for post-extraction dry socket alveolitis. The bio-adhesive 0.2% chlorhexidine gel could improve this action since its intra-alveolar positioning would allow a more direct action on the alveolus and more prolonged action of the medication. MATERIALS AND METHOD:We pres...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2006-03-01 00:00:00
abstract：:Oral lichenoid lesions related to contact are defined as oral-cavity eruptions with an identifiable etiology, and are clinically and histologically similar to oral lichen planus. Within this group are found oral lichenoid lesions related to contact with dental materials (OLLC), the most common being those related to s...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章,评审
doi：10.4317/medoral.14.e514
更新日期：2009-10-01 00:00:00
abstract：:Bisphosphonates are recently acquiring increasing relevance in the treatment of several diseases. In line with the increased use of these compounds, cases of mandibular osteonecrosis, and to a lesser extent, maxillary osteonecrosis, are being reported. This necrosis is difficult to treat in patients who usually have a...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：
更新日期：2006-01-01 00:00:00
abstract：:Odontogenic Calcificant Cystic Tumor (OCCT) is an infrequent injury. It arises from odontogenic epithelial rests present in the maxilla, jaw or gum. Gorlin and col. described the OCCT for first time as an own pathological entity in 1962. Clinically, the OCCT represents 1% of the odontogenic injuries. It is possible to...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章,评审
doi：
更新日期：2007-03-01 00:00:00
abstract：OBJECTIVES:to describe a bench model (workshop of abilities) for sinus floor elevation (SFE) training that simulates the surgical environment and to assess its effectiveness in terms of trainees' perception. STUDY DESIGN:thirty-six randomly selected postgraduate students entered this cross-sectional pilot study and as...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：10.4317/medoral.17701
更新日期：2012-07-01 00:00:00
abstract：BACKGROUND:Extensive literature exists about the use of the BFP in the treatment of oral defects but, to our knowledge, no article refers to the use of the BFP as a substitute of the membrane barriers for treatment of peri-implant bone defects. The aim was to evaluate the use of the buccal fat pad as a coating material...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：10.4317/medoral.20212
更新日期：2015-11-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to compare the effects in terms of resistance to fracture of the mandibular condyle and femoral head following different doses of zoledronic acid in an animal model. STUDY DESIGN:A total of 80 adult male Sprague-Dawley rats were included in a prospective randomized study. The animal...
journal_title：Medicina oral, patologia oral y cirugia bucal
pub_type： 杂志文章
doi：10.4317/medoral.18449
更新日期：2013-05-01 00:00:00
