Principal Component Analysis of the Effects of Environmental Enrichment and (-)-epigallocatechin-3-gallate on Age-Associated Learning Deficits in a Mouse Model of Down Syndrome.

abstract：:First-line treatment of major depression includes administration of a selective serotonin reuptake inhibitor (SSRI), yet studies suggest that remission rates following two trials of an SSRI are <50%. The authors examine the putative biological substrates underlying "treatment resistant depression (TRD)" with the goal ...

journal_title：Frontiers in behavioral neuroscience

authors： Coplan JD,Gopinath S,Abdallah CG,Berry BR

更新日期：2014-05-20 00:00:00

abstract：:Exergames are increasingly used to train both physical and cognitive functioning, but direct evidence whether and how exergames affect cortical activity is lacking. Although portable electroencephalography (EEG) can be used while exergaming, it is unknown whether brain activity will be obscured by movement artifacts. ...

journal_title：Frontiers in behavioral neuroscience

authors： Anders P,Lehmann T,Müller H,Grønvik KB,Skjæret-Maroni N,Baumeister J,Vereijken B

更新日期：2018-05-18 00:00:00

abstract：:In animals, emotional memory is classically assessed through pavlovian fear conditioning in which a neutral novel stimulus (conditioned stimulus) is paired with an aversive unconditioned stimulus. After conditioning, the conditioned stimulus elicits a fear response characterized by a wide range of behavioral and physi...

journal_title：Frontiers in behavioral neuroscience

authors： Hegoburu C,Shionoya K,Garcia S,Messaoudi B,Thévenet M,Mouly AM

更新日期：2011-05-19 00:00:00

abstract：:Selective serotonin reuptake inhibitors (SSRIs) are used extensively in the treatment of depression and anxiety disorders. The therapeutic benefits of SSRIs typically require several weeks of continuous treatment. Intriguingly, according to clinical reports, symptoms of anxiety may actually increase during the early s...

journal_title：Frontiers in behavioral neuroscience

authors： Ravinder S,Pillai AG,Chattarji S

更新日期：2011-12-28 00:00:00

abstract：:Rationale: Given datasets with a large or diverse set of predictors of aggression, machine learning (ML) provides efficient tools for identifying the most salient variables and building a parsimonious statistical model. ML techniques permit efficient exploration of data, have not been widely used in aggression researc...

journal_title：Frontiers in behavioral neuroscience

authors： Suchting R,Gowin JL,Green CE,Walss-Bass C,Lane SD

更新日期：2018-05-07 00:00:00

abstract：:Immediate early and constitutively expressed products of the Homer1 gene regulate the functional assembly of post-synaptic density proteins at glutamatergic synapses to influence excitatory neurotransmission and synaptic plasticity. Earlier studies of Homer1 gene knock-out (KO) mice indicated active, but distinct, rol...

journal_title：Frontiers in behavioral neuroscience

authors： Datko MC,Hu JH,Williams M,Reyes CM,Lominac KD,von Jonquieres G,Klugmann M,Worley PF,Szumlinski KK

更新日期：2017-11-01 00:00:00

abstract：:Maternal exposure to infection occurring mid-gestation produces a three-fold increase in the risk of schizophrenia in the offspring. The critical initiating factor appears to be the maternal immune activation (MIA) that follows infection. This process can be induced in rodents by exposure of pregnant dams to the viral...

journal_title：Frontiers in behavioral neuroscience

authors： Dickerson DD,Bilkey DK

更新日期：2013-12-27 00:00:00

abstract：:5-aza-2'-deoxycytidine (5-aza), an inhibitor of DNA methyltransferases (DNMTs), has been implicated in aversive memory and the function of brain region involved in processing emotion. However, little is known about the role of 5-aza in the reconsolidation of opiate withdrawal memory. In the present study, using the mo...

journal_title：Frontiers in behavioral neuroscience

authors： Liu P,Zhang J,Li M,Sui N

更新日期：2016-03-15 00:00:00

abstract：:Violence is widespread throughout the natural world, prominent examples being predatory violence between species, seasonal violent competition for mating rights and territories within species and food competition both within and between species. These interactions are generally between unrelated individuals with no so...

journal_title：Frontiers in behavioral neuroscience

authors： Broom M

更新日期：2009-11-16 00:00:00

abstract：:Anatomical investigations have revealed connections between the intralaminar thalamic nuclei and areas such as the superior colliculus (SC) that receive short latency input from visual and auditory primary sensory areas. The intralaminar nuclei in turn project to the major input nucleus of the basal ganglia, the stria...

journal_title：Frontiers in behavioral neuroscience

authors： Fisher SD,Reynolds JN

更新日期：2014-04-02 00:00:00

abstract：:Ecstatic epileptic seizures are a rare but compelling epileptic entity. During the first seconds of these seizures, ecstatic auras provoke feelings of well-being, intense serenity, bliss, and "enhanced self-awareness." They are associated with the impression of time dilation, and can be described as a mystic experienc...

journal_title：Frontiers in behavioral neuroscience

authors： Gschwind M,Picard F

更新日期：2016-02-17 00:00:00

abstract：:Opioid use is a widespread epidemic, and traumatic stress exposure is a critical risk factor in opioid use and relapse. There is a significant gap in our understanding of how stress contributes to heroin use, and there are limited studies investigating individual differences underlying stress reactivity and subsequent...

journal_title：Frontiers in behavioral neuroscience

authors： Stafford NP,Kazan TN,Donovan CM,Hart EE,Drugan RC,Charntikov S

更新日期：2019-06-25 00:00:00

abstract：:The ability to accurately integrate or bind stimuli from more than one sensory modality is highly dependent on the features of the stimuli, such as their intensity and relative timing. Previous studies have demonstrated that the ability to perceptually bind stimuli is impaired in various clinical conditions such as au...

journal_title：Frontiers in behavioral neuroscience

authors： Schormans AL,Allman BL

更新日期：2018-10-31 00:00:00

abstract：:In a conventional view of motor control, the human brain might employ an optimization principle that leads a stereotypical motor behavior which we observe as an averaged behavioral data over subjects. In this scenario, the inter-individual motor variability is considered as an observation noise. Here, we challenged th...

journal_title：Frontiers in behavioral neuroscience

authors： Kita K,Osu R,Hosoda C,Honda M,Hanakawa T,Izawa J

更新日期：2019-03-06 00:00:00

abstract：:Background: Women are twice as likely as men to develop major depression. The brain mechanisms underlying this sex disparity are not clear. Disruption of the glutamate-glutamine cycle has been implicated in psychiatric disturbances. This study identifies sex-based impairments in the glutamate-glutamine cycle involving...

journal_title：Frontiers in behavioral neuroscience

authors： Rappeneau V,Blaker A,Petro JR,Yamamoto BK,Shimamoto A

更新日期：2016-12-06 00:00:00

abstract：:Marijuana is a prevalent illicit substance used by adolescents, and several studies have indicated that adolescent use can lead to long-term cognitive deficits including problems with attention and memory. However, preclinical animal studies that observe cognitive deficits after cannabinoid exposure during adolescence...

journal_title：Frontiers in behavioral neuroscience

authors： Kirschmann EK,McCalley DM,Edwards CM,Torregrossa MM

更新日期：2017-07-21 00:00:00

abstract：:Adolescent behavior is typified by increased risk-taking, reward- and novelty-seeking, as well as an augmented need for social and environmental stimulation. This behavioral phenotype may result from alterations in outcome valuation or reward learning. In the present set of experiments, we directly compared adult and ...

journal_title：Frontiers in behavioral neuroscience

authors： Stolyarova A,Izquierdo A

更新日期：2015-05-07 00:00:00

abstract：:We previously developed rat experimental models based on the conditioned place preference (CPP) paradigm in which only four 15-min episodes of dyadic social interaction with a sex- and weight-matched male Sprague Dawley (SD) rat (1) reversed CPP from cocaine to social interaction despite continuing cocaine training, a...

journal_title：Frontiers in behavioral neuroscience

authors： Kummer KK,Hofhansel L,Barwitz CM,Schardl A,Prast JM,Salti A,El Rawas R,Zernig G

更新日期：2014-10-17 00:00:00

abstract：:DARPP-32 (PPP1R1B) was discovered as a substrate of cAMP-dependent protein kinase (PKA) enriched in dopamine-innervated brain areas. It is one of three related, PKA-regulated inhibitors of protein phosphatase-1 (PP1). These inhibitors seem to have appeared in early vertebrate ancestors, possibly Gnathostomes. DARPP-32...

journal_title：Frontiers in behavioral neuroscience

authors： Yger M,Girault JA

更新日期：2011-09-08 00:00:00

abstract：:Parkinsonian patients experience not only the physical discomfort of motor disorders but also the considerable psychological distress caused by cognitive deficits and behavioral disorders. These two factors can result in a disruption of social relationships during the symptomatic and even the presymptomatic motor stat...

journal_title：Frontiers in behavioral neuroscience

authors： Durand E,Petit O,Tremblay L,Zimmer C,Sgambato-Faure V,Chassain C,Laurent M,Pereira B,Silberberg C,Durif F

更新日期：2015-02-26 00:00:00

abstract：:Somatostatin (SOM) and somatostatin receptors (SSTR1-4) are present in all olfactory structures, including the olfactory bulb (OB), where SOM modulates physiological gamma rhythms and olfactory discrimination responses. In this work, histological, viral tracing and transgenic approaches were used to characterize SOM c...

journal_title：Frontiers in behavioral neuroscience

authors： Nocera S,Simon A,Fiquet O,Chen Y,Gascuel J,Datiche F,Schneider N,Epelbaum J,Viollet C

更新日期：2019-04-09 00:00:00

abstract：:Down syndrome (DS) is an aneuploidy syndrome that is caused by trisomy for human chromosome 21 resulting in a characteristic cognitive and behavioral phenotype, which includes executive functioning and adaptive behavior difficulties possibly due to prefrontal cortex (PFC) deficits. DS also present a high risk for earl...

journal_title：Frontiers in behavioral neuroscience

authors： Del Hoyo L,Xicota L,Langohr K,Sánchez-Benavides G,de Sola S,Cuenca-Royo A,Rodriguez J,Rodríguez-Morató J,Farré M,Dierssen M,de la Torre R,TESDAD Study Group.

更新日期：2016-10-17 00:00:00

abstract：:Very preterm (VPT) infants need long-lasting hospitalization in the Neonatal Intensive Care Unit (NICU) during which they are daily exposed to pain-related stress. Alterations of DNA methylation at the promoter region of the SLC6A4 have been associated with early adverse experiences in infants. The main aim of the pre...

journal_title：Frontiers in behavioral neuroscience

authors： Provenzi L,Fumagalli M,Sirgiovanni I,Giorda R,Pozzoli U,Morandi F,Beri S,Menozzi G,Mosca F,Borgatti R,Montirosso R

更新日期：2015-04-21 00:00:00

abstract：:Invertebrates are used extensively as model species to investigate neuro-endocrine processes regulating behaviors, and many of these processes may be extrapolated to vertebrates. However, when it comes to reproductive processes, many of these model species differ notably in their mode of reproduction. A point in case ...

journal_title：Frontiers in behavioral neuroscience

authors： Koene JM

更新日期：2010-10-21 00:00:00

abstract：:Increased reactivity to stress is maladaptive and linked to abnormal behaviors and psychopathology. Chronic unpredictable stress (CUS) alters catecholaminergic neurotransmission and remodels neuronal circuits involved in learning, attention and decision making. Glial-derived neurotrophic factor (GDNF) is essential for...

journal_title：Frontiers in behavioral neuroscience

authors： Buhusi M,Brown CK,Buhusi CV

更新日期：2017-10-10 00:00:00

abstract：:Ecological communities are organized in trophic levels that share manifold interactions forming complex food webs. Infochemicals can further modify these interactions, e.g., by inducing defenses in prey. The micro-crustacean Daphnia is able to respond to predator-specific chemical cues indicating an increased predatio...

journal_title：Frontiers in behavioral neuroscience

authors： Weiss LC

更新日期：2019-01-18 00:00:00

abstract：:Emotionally arousing experiences and stress influence cognitive processes and vice versa. Understanding the relations and interactions between these three systems forms the core of this study. We tested two inbred mouse strains (BALB/c, C57BL/6J; male; 3-month-old) for glucocorticoid stress system markers (expression ...

journal_title：Frontiers in behavioral neuroscience

authors： Brinks V,van der Mark M,de Kloet R,Oitzl M

更新日期：2007-12-30 00:00:00

abstract：:Interactions between social experiences at different stages of development (e.g., with parents as juveniles and peers as subadults) can profoundly shape the expression of social behavior. Rarely are the influences of more than one stage of developmental sensitivity to social environment investigated simultaneously. Fu...

journal_title：Frontiers in behavioral neuroscience

authors： Prounis GS,Ophir AG

更新日期：2019-09-13 00:00:00

abstract：:Stimuli of the environment, like objects, systematically activate the actions they are associated to. These activations occur extremely fast. Nevertheless, behavioral data reveal that, in most cases, these activations are then automatically inhibited, around 100 ms after the occurrence of the stimulus. We thus tested ...

journal_title：Frontiers in behavioral neuroscience

authors： Debruille JB,Touzel M,Segal J,Snidal C,Renoult L

更新日期：2019-05-08 00:00:00

abstract：:Magnetoreception can play a substantial role in long distance navigation by animals. I hypothesize that locomotion guided by a magnetic compass sense could also play a role in short distance navigation. Animals identify mates, prey, or other short distance navigational goals using different sensory modalities (olfacti...

journal_title：Frontiers in behavioral neuroscience

authors： Wyeth RC

更新日期：2010-07-30 00:00:00