Modeling spontaneous activity across an excitable epithelium: Support for a coordination scenario of early neural evolution.

abstract：:Balanced states in large networks are a usual hypothesis for explaining the variability of neural activity in cortical systems. In this regime the statistics of the inputs is characterized by static and dynamic fluctuations. The dynamic fluctuations have a Gaussian distribution. Such statistics allows to use reverse c...

journal_title：Frontiers in computational neuroscience

authors： Pool RR,Mato G

更新日期：2011-10-12 00:00:00

abstract：:We present a high-capacity model for one-shot association learning (hetero-associative memory) in sparse networks. We assume that basic patterns are pre-learned in networks and associations between two patterns are presented only once and have to be learned immediately. The model is a combination of an Amit-Fusi like ...

journal_title：Frontiers in computational neuroscience

authors： Einarsson H,Lengler J,Steger A

更新日期：2014-11-07 00:00:00

abstract：:With the emergence of online publishing, opportunities to maximize transparency of scientific research have grown considerably. However, these possibilities are still only marginally used. We argue for the implementation of (1) peer-reviewed peer review, (2) transparent editorial hierarchies, and (3) online data publi...

journal_title：Frontiers in computational neuroscience

authors： Wicherts JM,Kievit RA,Bakker M,Borsboom D

更新日期：2012-04-03 00:00:00

abstract：:Automatic segmentation of Multiple Sclerosis (MS) lesions from Magnetic Resonance Imaging (MRI) images is essential for clinical assessment and treatment planning of MS. Recent years have seen an increasing use of Convolutional Neural Networks (CNNs) for this task. Although these methods provide accurate segmentation,...

journal_title：Frontiers in computational neuroscience

authors： Ackaouy A,Courty N,Vallée E,Commowick O,Barillot C,Galassi F

更新日期：2020-03-09 00:00:00

abstract：:Synaptic transmission is both history-dependent and stochastic, resulting in varying responses to presentations of the same presynaptic stimulus. This complicates attempts to infer synaptic parameters and has led to the proposal of a number of different strategies for their quantification. Recently Bayesian approaches...

journal_title：Frontiers in computational neuroscience

authors： Bird AD,Wall MJ,Richardson MJ

更新日期：2016-11-25 00:00:00

abstract：:Proprioceptive afferents from muscle spindles encode information about peripheral joint movements for the central nervous system (CNS). The sensitivity of muscle spindle is nonlinearly dependent on the activation of gamma (γ) motoneurons in the spinal cord that receives inputs from the motor cortex. How fusimotor cont...

journal_title：Frontiers in computational neuroscience

authors： Lan N,He X

更新日期：2012-08-30 00:00:00

abstract：:Image registration and segmentation are the two most studied problems in medical image analysis. Deep learning algorithms have recently gained a lot of attention due to their success and state-of-the-art results in variety of problems and communities. In this paper, we propose a novel, efficient, and multi-task algori...

journal_title：Frontiers in computational neuroscience

authors： Estienne T,Lerousseau M,Vakalopoulou M,Alvarez Andres E,Battistella E,Carré A,Chandra S,Christodoulidis S,Sahasrabudhe M,Sun R,Robert C,Talbot H,Paragios N,Deutsch E

更新日期：2020-03-20 00:00:00

abstract：:We present a phenomenological model of electrically stimulated auditory nerve fibers (ANFs). The model reproduces the probabilistic and temporal properties of the ANF response to both monophasic and biphasic stimuli, in isolation. The main contribution of the model lies in its ability to reproduce statistics of the AN...

journal_title：Frontiers in computational neuroscience

authors： Horne CD,Sumner CJ,Seeber BU

更新日期：2016-02-08 00:00:00

abstract：:The correlation structure of neural activity is believed to play a major role in the encoding and possibly the decoding of information in neural populations. Recently, several methods were developed for exactly controlling the correlation structure of multi-channel synthetic spike trains (Brette, 2009; Krumin and Shoh...

journal_title：Frontiers in computational neuroscience

authors： Krumin M,Reutsky I,Shoham S

更新日期：2010-11-19 00:00:00

abstract：:The output of primary visual cortex (V1) is a piecemeal representation of the visual scene and the response of any one cell cannot unambiguously guide sensorimotor behavior. It remains unsolved how subsequent stages of cortical processing combine ("pool") these early visual signals into a coherent representation. We (...

journal_title：Frontiers in computational neuroscience

authors： Rocchi F,Ledgeway T,Webb BS

更新日期：2013-11-18 00:00:00

abstract：:A neural code based on sequences of spikes can consume a significant portion of the brain's energy budget. Thus, energy considerations would dictate that spiking activity be kept as low as possible. However, a high spike-rate improves the coding and representation of signals in spike trains, particularly in sensory sy...

journal_title：Frontiers in computational neuroscience

authors： Jones DL,Johnson EC,Ratnam R

更新日期：2015-06-02 00:00:00

abstract：:Despite an abundance of computational models for learning of synaptic weights, there has been relatively little research on structural plasticity, i.e., the creation and elimination of synapses. Especially, it is not clear how structural plasticity works in concert with spike-timing-dependent plasticity (STDP) and wha...

journal_title：Frontiers in computational neuroscience

authors： Spiess R,George R,Cook M,Diehl PU

更新日期：2016-09-08 00:00:00

abstract：:Drosophila larvae crawl by peristaltic waves of muscle contractions, which propagate along the animal body and involve the simultaneous contraction of the left and right side of each segment. Coordinated propagation of contraction does not require sensory input, suggesting that movement is generated by a central patte...

journal_title：Frontiers in computational neuroscience

authors： Gjorgjieva J,Berni J,Evers JF,Eglen SJ

更新日期：2013-04-04 00:00:00

abstract：:Parkinson's disease (PD) is a neurodegenerative disorder which follows from cell loss of dopaminergic neurons in the substantia nigra pars compacta (SNc), a nucleus in the basal ganglia (BG). Deep brain stimulation (DBS) is an electrical therapy that modulates the pathological activity to treat the motor symptoms of P...

journal_title：Frontiers in computational neuroscience

authors： Summerson SR,Aazhang B,Kemere C

更新日期：2015-06-26 00:00:00

abstract：:Biological realism of dendritic morphologies is important for simulating electrical stimulation of brain tissue. By adding point process modeling and conditional sampling to existing generation strategies, we provide a novel means of reproducing the nuanced branching behavior that occurs in different layers of granule...

journal_title：Frontiers in computational neuroscience

authors： Chou ZZ,Yu GJ,Berger TW

更新日期：2020-04-09 00:00:00

abstract：:Often we need to perform tasks in an environment that changes stochastically. In these situations it is important to learn the statistics of sequences of events in order to predict the future and the outcome of our actions. The statistical description of many of these sequences can be reduced to the set of probabiliti...

journal_title：Frontiers in computational neuroscience

authors： Ostojic S,Fusi S

更新日期：2013-04-12 00:00:00

abstract：:Over the last decade robotics has attracted a great deal of interest from teachers and researchers as a valuable educational tool from preschool to highschool levels. The implementation of social-support behaviors in robot tutors, in particular in the emotional dimension, can make a significant contribution to learnin...

journal_title：Frontiers in computational neuroscience

authors： Imbernón Cuadrado LE,Manjarrés Riesco Á,De La Paz López F

更新日期：2016-08-03 00:00:00

abstract：:Many of the synapses in the basal ganglia display short-term plasticity. Still, computational models have not yet been used to investigate how this affects signaling. Here we use a model of the basal ganglia network, constrained by available data, to quantitatively investigate how synaptic short-term plasticity affect...

journal_title：Frontiers in computational neuroscience

authors： Lindahl M,Kamali Sarvestani I,Ekeberg O,Kotaleski JH

更新日期：2013-06-19 00:00:00

abstract：:Previous studies have shown that the auditory cortex can enhance the perception of behaviorally important sounds in the presence of background noise, but the mechanisms by which it does this are not yet elucidated. Rapid plasticity of spectrotemporal receptive fields (STRFs) in the primary (A1) cortical neurons is obs...

journal_title：Frontiers in computational neuroscience

authors： Chambers JD,Elgueda D,Fritz JB,Shamma SA,Burkitt AN,Grayden DB

更新日期：2019-05-24 00:00:00

abstract：:In vivo and in vitro experimental studies have found that blocking electrical interactions connecting GABAergic interneurons reduces oscillatory activity in the gamma range in cortex. However, recent theoretical works have shown that the ability of electrical synapses to promote or impede synchrony, when alone, depend...

journal_title：Frontiers in computational neuroscience

authors： Pfeuty B,Golomb D,Mato G,Hansel D

更新日期：2007-11-02 00:00:00

abstract：:Deep brain stimulation (DBS) leads with radially distributed electrodes have potential to improve clinical outcomes through more selective targeting of pathways and networks within the brain. However, increasing the number of electrodes on clinical DBS leads by replacing conventional cylindrical shell electrodes with ...

journal_title：Frontiers in computational neuroscience

authors： Teplitzky BA,Zitella LM,Xiao Y,Johnson MD

更新日期：2016-06-10 00:00:00

abstract：:The human brain is a complex system composed by several large scale intrinsic networks with distinct functions. The low frequency oscillation (LFO) signal of blood oxygen level dependent (BOLD), measured through resting-state fMRI, reflects the spontaneous neural activity of these networks. We propose to characterize ...

journal_title：Frontiers in computational neuroscience

authors： Qi S,Gao Q,Shen J,Teng Y,Xie X,Sun Y,Wu J

更新日期：2018-08-03 00:00:00

abstract：:Burst spike patterns are common in regions of the hippocampal formation such as the subiculum and medial entorhinal cortex (MEC). Neurons in these areas are immersed in extracellular electrical potential fluctuations often recorded as the local field potential (LFP). LFP rhythms within different frequency bands are li...

journal_title：Frontiers in computational neuroscience

authors： Constantinou M,Gonzalo Cogno S,Elijah DH,Kropff E,Gigg J,Samengo I,Montemurro MA

更新日期：2016-12-26 00:00:00

abstract：:Pitch is a perceptual correlate of periodicity. Sounds with distinct spectra can elicit the same pitch. Despite the importance of pitch perception, understanding the cellular mechanism of pitch perception is still a major challenge and a mechanistic model of pitch is lacking. A multi-stage neuronal network model is de...

journal_title：Frontiers in computational neuroscience

authors： Huang C,Rinzel J

更新日期：2016-06-16 00:00:00

abstract：:Scientific research produces new knowledge, technologies, and clinical treatments that can lead to enormous returns. Often, the path from basic research to new paradigms and direct impact on society takes time. Precise quantification of scientific output in the short-term is not an easy task but is critical for evalua...

journal_title：Frontiers in computational neuroscience

authors： Kreiman G,Maunsell JH

更新日期：2011-11-10 00:00:00

abstract：:The role of dendritic spiking mechanisms in neural processing is so far poorly understood. To investigate the role of calcium spikes in the functional properties of the single neuron and recurrent networks, we investigated a three compartment neuron model of the layer 5 pyramidal neuron with calcium dynamics in the di...

journal_title：Frontiers in computational neuroscience

authors： Chua Y,Morrison A

更新日期：2016-07-22 00:00:00

abstract：:Dopaminergic neurons in the mammalian substantia nigra display characteristic phasic responses to stimuli which reliably predict the receipt of primary rewards. These responses have been suggested to encode reward prediction-errors similar to those used in reinforcement learning. Here, we propose a model of dopaminerg...

journal_title：Frontiers in computational neuroscience

authors： Chorley P,Seth AK

更新日期：2011-05-18 00:00:00

abstract：:Neuronal action potentials or spikes provide a long-range, noise-resistant means of communication between neurons. As point processes single spikes contain little information in themselves, i.e., outside the context of spikes from other neurons. Moreover, they may fail to cross a synapse. A burst, which consists of a ...

journal_title：Frontiers in computational neuroscience

authors： Zeldenrust F,Wadman WJ,Englitz B

更新日期：2018-07-06 00:00:00

abstract：:What are the functional neuroimaging measurements required for more fully characterizing the events and locations of neocortical activity? A prime assumption has been that modulation of cortical activity will inevitably be reflected in changes in energy utilization (for the most part) changes of glucose and oxygen con...

journal_title：Frontiers in computational neuroscience

authors： Robinson SE,Mandell AJ,Coppola R

更新日期：2013-01-24 00:00:00

abstract：:Background: Convolution neural networks (CNN) is increasingly used in computer science and finds more and more applications in different fields. However, analyzing brain network with CNN is not trivial, due to the non-Euclidean characteristics of brain network built by graph theory. Method: To address this problem, we...

journal_title：Frontiers in computational neuroscience

authors： Meng L,Xiang J

更新日期：2018-12-10 00:00:00