Oral contraceptives and antibiotics. A cross-sectional study about patients' knowledge in general practice.

Abstract:

BACKGROUND:The evidence regarding oral contraceptives and its effectiveness with concomitant ingestion of antibiotics is conflicting. Until evidence becomes clearer, patients should be aware of this possible interaction. The aim of this study was to assess the knowledge and the source of information about this interaction in GP patients in Austria. METHODS:Within the framework of the APRES study, 20 Austrian GPs were purposefully selected from among a GP research network and were asked to recruit 200 patients each. The patient cohort was asked to complete a questionnaire. Subsequent analysis included descriptive statistics, statistical tests and logistic regression models. FINDINGS:Overall, 3280 questionnaires could be used for analysis. Of these, 29.7 % (n = 974) of patients acknowledged an awareness of the interaction of antibiotics with OCPs. Women under the age of 46 years acknowledged this interaction in 52.3 % of cases. Positive associations for the belief in an existing interaction in women were identified with age (OR 2.2) and having read the package inserts (OR 1.6). Further, belief was recognized in males based on age (OR 2.5) and tertiary education (OR 2.0). The main source of information regarding antibiotics was the GP (55.9 %). CONCLUSIONS:Less than one-third of all participants and half of the women in the reproductive age acknowledged an interaction between antibiotics and OCPs. Since the GP is the main source of information, this finding depicts a large potential for knowledge transfer within the primary health care setting. A multifaceted strategy is needed at both the population and the GP level to improve awareness and to address these educational gaps.

journal_name

Reprod Health

journal_title

Reproductive health

authors

Hoffmann K,George A,Heschl L,Leifheit AK,Maier M

doi

10.1186/s12978-015-0037-4

subject

Has Abstract

pub_date

2015-05-14 00:00:00

pages

43

issn

1742-4755

pii

10.1186/s12978-015-0037-4

journal_volume

12

pub_type

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