Abstract：
BACKGROUND:Hypertension affects about 10% of pregnancies and is responsible for both maternal and neonatal devastating complications such as eclampsia, HELLP syndrome, prematurity and maternal and neonatal death. The resolution of the disease occurs in the first twelve weeks postpartum. The behavior of blood pressure and occurrence of very high blood pressure episodes among women with severe preeclampsia is related to remodeling of the dynamics of body fluids with consequent increase in intravascular volume. The persistence of hypertension in critical levels results in increased puerperal morbidity. OBJECTIVES:To evaluate the effectiveness of furosemide in accelerating blood pressure recovery among women with severe preeclampsia. METHODS/DESIGN:A triple-masked placebo controlled clinical trial, will be conducted including 120 postpartum women with severe preeclampsia, after eclampsia prophylaxis with magnesium sulfate and with adequate diuresis. Women with chronic hypertension and users of diuretics will be deleted. Informed consent will be obtained from all participants. Patients will be randomized to receive furosemide (40 mg orally every twenty four hours) or placebo. The variables are systolic and diastolic blood pressure, frequency of hypertensive crises, need for maintenance of antihypertensive therapy, number of antihypertensive agents used to control blood pressure, urine output, length of hospital stay, adverse effects and maternal complications. This study was approved by the Research Ethics Committee in humans of our institution. All participants will be duly informed about the aims of the project and will be included only if they agree to participate voluntarily, signing the informed consent. TRIAL REGISTRATION:This study was registered on Clinical Trials.gov under the number NCT02163655. ( http://clinicaltrials.gov/show/NCT02163655).
journal_name
Reprod Healthjournal_title
Reproductive healthauthors
Cursino T,Katz L,Coutinho I,Amorim Mdoi
10.1186/s12978-015-0057-0subject
Has Abstractpub_date
2015-08-05 00:00:00pages
66issn
1742-4755pii
10.1186/s12978-015-0057-0journal_volume
12pub_type
杂志文章,随机对照试验abstract：:Abortion is legally restricted in most of Latin America where 95% of the 4.4 million abortions performed annually are unsafe. Medical abortion (MA) refers to the use of a drug or a combination of drugs to terminate pregnancy. Mifepristone followed by misoprostol is the most effective and recommended regime. In setting...
journal_title：Reproductive health
pub_type： 杂志文章,评审
doi：10.1186/1742-4755-9-34
更新日期：2012-12-22 00:00:00
abstract：BACKGROUND:Turkey hosts the world's largest community of Syrians displaced by the conflict. The Minimum Initial Service Package (MISP) is a coordinated set of priority reproductive health services. There is not any scoping review assessing the RH situation of Syrian refugees in Turkey within the framework of the MISP o...
journal_title：Reproductive health
pub_type： 杂志文章,评审
doi：10.1186/s12978-020-00948-1
更新日期：2020-06-22 00:00:00
abstract：BACKGROUND:Stringent donor-screening criteria and legislation prohibiting payment for donor gametes have contributed to the radical decline of donor insemination (DI) using sperm provided by Canadian men. Thus, many individuals rely on imported sperm. This paper examines the feasibility of an altruistic sperm donation ...
journal_title：Reproductive health
pub_type： 杂志文章
doi：10.1186/s12978-016-0275-0
更新日期：2017-01-14 00:00:00
abstract：BACKGROUND:Having a health worker with midwifery skills present at delivery is one of the key interventions to reduce maternal and newborn mortality. We sought to estimate the frequencies of (a) skilled birth attendant coverage, (b) institutional delivery, and (c) the combination of place of delivery and type of attend...
journal_title：Reproductive health
pub_type： 杂志文章
doi：10.1186/s12978-016-0192-2
更新日期：2016-06-17 00:00:00
abstract：BACKGROUND:Parents play an important role in promoting the sexual health of their adolescents. However, many parents experience several challenges. The purpose of this study was to explore the concerns and educational needs of Iranian parents regarding the sexual health of their male adolescents. METHODS:This qualitat...
journal_title：Reproductive health
pub_type： 杂志文章
doi：10.1186/s12978-020-0883-6
更新日期：2020-02-14 00:00:00
abstract：BACKGROUND:Globally, an estimated 287 000 maternal deaths occurred in 2010 annually as a result of complications of pregnancy and childbirth. Sub-Saharan Africa and Southern Asia were accounted for 85% of the global burden (245 000 maternal deaths) including Ethiopia. Obstetric related complications cannot be reliably ...
journal_title：Reproductive health
pub_type： 杂志文章
doi：10.1186/1742-4755-11-55
更新日期：2014-07-20 00:00:00
abstract：BACKGROUND:Worldwide, about 287 000 women die each year from mostly preventable complications related to pregnancy and childbirth. A disproportionately high number of these deaths occur in sub-Saharan Africa. The Abiye ('Safe Motherhood') project in the Ifedore Local Government Area (LGA) of Ondo-State of Nigeria aimed...
journal_title：Reproductive health
pub_type： 杂志文章
doi：10.1186/1742-4755-11-8
更新日期：2014-01-20 00:00:00
abstract：BACKGROUND:Greater paternal engagement is positively associated with improved access to and utilization of maternal services. Despite evidence that male involvement increased uptake of maternal and child services, studies show that few men are participating in MNCH programs. Community leaders have long been engaged in ...
journal_title：Reproductive health
pub_type： 杂志文章
doi：10.1186/s12978-019-0752-3
更新日期：2019-06-21 00:00:00
abstract：:The practice and timing of routine antenatal visits for healthy pregnant women, introduced arbitrarily and without evidence of effectiveness, have become entrenched in obstetric practice over the last century. In 2001 the large, cluster randomized WHO Antenatal Care Trial concluded that a goal-orientated package of an...
journal_title：Reproductive health
pub_type： 杂志文章
doi：10.1186/1742-4755-10-20
更新日期：2013-04-12 00:00:00
abstract：BACKGROUND:Disrespectful and abusive treatment during childbirth is a violation of women's right to dignified, respectful healthcare throughout pregnancy and childbirth. Although reports point out that marginalized groups in society such as single mothers are particularly vulnerable to abusive and disrespectful care, t...
journal_title：Reproductive health
pub_type： 杂志文章
doi：10.1186/s12978-017-0290-9
更新日期：2017-03-04 00:00:00
abstract：BACKGROUND:Sub-Saharan Africa accounts for approximately 66% of global maternal deaths. Poor person-centered maternity care, which emphasizes the quality of patient experience, contributes both directly and indirectly to these poor outcomes. Yet, few studies in low resource settings have examined what is important to w...
journal_title：Reproductive health
pub_type： 杂志文章
doi：10.1186/s12978-017-0446-7
更新日期：2017-12-29 00:00:00
abstract：BACKGROUND:Healthcare providers have a responsibility to provide pain management support to women during labor. Labor pain management in low and middle income countries primarily relies on non-pharmacological methods, as there is little access to pharmacologic pain management. This study aimed to determine the utilizat...
journal_title：Reproductive health
pub_type： 杂志文章
doi：10.1186/s12978-020-01043-1
更新日期：2020-11-23 00:00:00
abstract：BACKGROUND:Utilization of reproductive health services is an important component in preventing adolescents from different sexual and reproductive health problems. As a result, the extent of their service utilization should be determined before implementing any kind of interventions. Therefore, this study was aimed at a...
journal_title：Reproductive health
pub_type： 杂志文章
doi：10.1186/s12978-018-0659-4
更新日期：2018-12-27 00:00:00
abstract：BACKGROUND:Female genital mutilation/cutting (FGM/C) is a common harmful traditional practice in many communities in Africa and to a lesser extent in Middle East and other regions in the world. In order to better understand publishing on this topic, we conducted a bibliometric study on FGM/C. Bibliometric analyses can ...
journal_title：Reproductive health
pub_type： 杂志文章
doi：10.1186/s12978-016-0243-8
更新日期：2016-10-10 00:00:00
abstract：BACKGROUND:After the 1968 United Nations International Conference on Human Rights, access to family planning services became a human right. Such a service is of central importance to women's empowerment and is empirically needed to provide adequate healthcare. For registered refugees and asylum seekers in Germany compl...
journal_title：Reproductive health
pub_type： 杂志文章
doi：10.1186/s12978-020-00962-3
更新日期：2020-07-29 00:00:00
abstract：BACKGROUND:Female Genital Mutilation/Cutting (FGM/C) is a harmful traditional practice with severe health complications, deeply rooted in many Sub-Saharan African countries. In The Gambia, the prevalence of FGM/C is 78.3% in women aged between 15 and 49 years. The objective of this study is to perform a first evaluatio...
journal_title：Reproductive health
pub_type： 杂志文章
doi：10.1186/1742-4755-8-26
更新日期：2011-10-03 00:00:00
abstract：BACKGROUND:To find out about the prenatal diagnosis rate of myelomeningocele (MMC) by ultrasound scan in patients referred to the Children's Hospital Medical Center in Tehran, Iran from July 2004 to July 2005. METHODS:We included 140 children born with MMC and who were referred for management, surgery and treatment of...
journal_title：Reproductive health
pub_type： 杂志文章
doi：10.1186/1742-4755-3-6
更新日期：2006-07-18 00:00:00
abstract：BACKGROUND:The introduction of home digital ovulation tests (OTs) has provided a simple solution for women wishing to optimise the timing of intercourse when trying to conceive. However, despite this, very little is understood about women's experiences of using these tests. METHODS:We carried out qualitative, semi-str...
journal_title：Reproductive health
pub_type： 杂志文章,随机对照试验
doi：10.1186/s12978-015-0103-y
更新日期：2015-12-21 00:00:00
abstract：BACKGROUND:A cultural preference for sons has been well documented in India, resulting in skewed sex ratios, especially exhibited in northwest India. Previous research has shown that family sex composition is associated with family planning (FP) use and couples' desire for more children. This study examines family sex ...
journal_title：Reproductive health
pub_type： 杂志文章
doi：10.1186/1742-4755-10-48
更新日期：2013-09-11 00:00:00
abstract：BACKGROUND:Pregnancy and parenthood are known to be high-risk times for mental health. However, less is known about the mental health of pregnant adolescents or adolescent parents. Despite the substantial literature on the risks associated with adolescent pregnancy, there is limited evidence on best practices for preve...
journal_title：Reproductive health
pub_type： 杂志文章,评审
doi：10.1186/s12978-020-00913-y
更新日期：2020-05-14 00:00:00
abstract：OBJECTIVE:To evaluate the effectiveness and safety of polyunsaturated fatty acids for the treatment of the premenstrual syndrome (PMS) using a graded symptom scale and to assess the effect of this treatment on basal plasma levels of prolactin and total cholesterol. METHODS:A randomized, double-blind, placebo-controlle...
journal_title：Reproductive health
pub_type： 杂志文章,随机对照试验
doi：10.1186/1742-4755-8-2
更新日期：2011-01-17 00:00:00
abstract：BACKGROUND:Paternal preconception risk factors such as smoking, exposure to environmental substances, medication use, overweight and advanced age correlate with the occurrence of malformations and birth defects in the offspring. Nonetheless, the prevalence of risk factors for adverse pregnancy outcomes in the male popu...
journal_title：Reproductive health
pub_type： 杂志文章
doi：10.1186/s12978-016-0156-6
更新日期：2016-04-14 00:00:00
abstract：BACKGROUND:The decreased reproductive capacity of men is an important factor contributing to infertility. Accumulating evidence has shown that Electromagnetic radiation potentially has negative effects on human health. However, whether radio frequency electromagnetic radiation (RF-EMR) affects the human reproductive sy...
journal_title：Reproductive health
pub_type： 杂志文章
doi：10.1186/s12978-015-0062-3
更新日期：2015-08-04 00:00:00
abstract：BACKGROUND:Human papillomavirus (HPV) infection plays key role in the development of cervical cancer. The purpose of this study was to investigate socioeconomic and lifestyle factors associated with HPV infection in pregnant women in Beijing, China. METHODS:An age matched case-control study designed with 66 women as t...
journal_title：Reproductive health
pub_type： 杂志文章
doi：10.1186/s12978-018-0645-x
更新日期：2018-12-06 00:00:00
abstract：BACKGROUND:Mother-to-child transmission of HIV (MTCT) accounts for over 95% of all paediatric HIV infections worldwide. Several studies have shown that male participation in the antenatal care of their spouses together with couple counselling and testing for HIV, increases use of the interventions for HIV prevention. T...
journal_title：Reproductive health
pub_type： 杂志文章
doi：10.1186/1742-4755-7-12
更新日期：2010-06-23 00:00:00
abstract：:Traditional approaches to improving adolescent sexual and reproductive health (ASRH) have focused on changing individual behavior, with little emphasis on addressing the factors that contribute to this behavior: biological changes; the influence of family and friends; the communities in which young people live; and ac...
journal_title：Reproductive health
pub_type： 杂志文章
doi：10.1186/s12978-016-0191-3
更新日期：2016-06-13 00:00:00
abstract：BACKGROUND:The physical and psychological impact of female genital mutilation / cutting (FGM/C) can be substantial, long term, and irreversible. Parts of the health sector in Australia have developed guidelines in the management of FGM/C, but large gaps exist in community and professional knowledge of the consequences ...
journal_title：Reproductive health
pub_type： 杂志文章,评审
doi：10.1186/s12978-017-0324-3
更新日期：2017-05-18 00:00:00
abstract：BACKGROUND:It is well-established that couples' fecundities vary widely. Each couple has a relatively constant monthly probability of conceiving, which can vary from zero to quite high. This underlying probability is usually expressed as the time (number of menstrual cycles) the couple requires to conceive. Couples wit...
journal_title：Reproductive health
pub_type： 杂志文章
doi：10.1186/s12978-019-0754-1
更新日期：2019-06-24 00:00:00
abstract：BACKGROUND:Adolescent girls between 15 and 19 years give birth to around 16 million babies each year, around 11% of births worldwide. We sought to determine whether adolescent mothers are at higher risk of maternal and perinatal adverse outcomes compared with mothers aged 20-24 years in a prospective, population-based ...
journal_title：Reproductive health
pub_type： 杂志文章,多中心研究
doi：10.1186/1742-4755-12-S2-S8
更新日期：2015-01-01 00:00:00
abstract：:Over the last 30 years, conservative power in the United States, financed and organized by Christian fundamentalist sects, the Catholic Church, and conservative corporate and political leadership, has become more threatening and potentially destabilizing of progressive democratic principles and practices. Powerful int...
journal_title：Reproductive health
pub_type： 杂志文章
doi：10.1186/1742-4755-8-1
更新日期：2011-01-05 00:00:00
