Abstract:
:In Parkinson's disease (PD), internal cueing mechanisms are impaired leading to symptoms like hypokinesia. However, external cues can improve movement execution by using cortical resources. These cortical processes can be affected by cognitive decline in dementia. It is still unclear how dementia in PD influences external cueing. We investigated a group of 25 PD patients with dementia (PDD) and 25 non-demented PD patients (PDnD) matched by age, sex, and disease duration in a simple reaction time task using an additional acoustic cue. PDD patients benefited from the additional cue in similar magnitude as did PDnD patients. However, withdrawal of the cue led to a significantly increased reaction time in the PDD group compared to the PDnD patients. Our results indicate that even PDD patients can benefit from strategies using external cue presentation but the process of cognitive worsening can reduce the effect when cues are withdrawn.
journal_name
Front Neuroljournal_title
Frontiers in neurologyauthors
Gräber S,Liepelt-Scarfone I,Csoti I,Maetzler W,Sultan F,Berg Ddoi
10.3389/fneur.2014.00236subject
Has Abstractpub_date
2014-11-17 00:00:00pages
236issn
1664-2295journal_volume
5pub_type
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journal_title:Frontiers in neurology
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pub_type: 杂志文章
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journal_title:Frontiers in neurology
pub_type: 杂志文章
doi:10.3389/fneur.2020.00058
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pub_type: 杂志文章
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pub_type: 杂志文章
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pub_type: 杂志文章
doi:10.3389/fneur.2017.00128
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journal_title:Frontiers in neurology
pub_type: 杂志文章
doi:10.3389/fneur.2019.00390
更新日期:2019-04-17 00:00:00
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pub_type: 杂志文章,评审
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pub_type: 杂志文章
doi:10.3389/fneur.2020.529930
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pub_type: 杂志文章
doi:10.3389/fneur.2019.00945
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journal_title:Frontiers in neurology
pub_type: 杂志文章,评审
doi:10.3389/fneur.2014.00105
更新日期:2014-06-25 00:00:00
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pub_type: 杂志文章
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journal_title:Frontiers in neurology
pub_type: 杂志文章,评审
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pub_type: 杂志文章
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journal_title:Frontiers in neurology
pub_type: 杂志文章
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pub_type: 杂志文章
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