Brain Amyloid Burden and Resting-State Functional Connectivity in Late Middle-Aged Hispanics.

abstract：Objective:The aim of this study was to detect the key changes during sit-to-stand (STS) movement cycle in hemiparetic stroke survivors using a five-phase kinematic and kinetic analysis. Methods:Twenty-five subacute stroke survivors and 17 age-matched healthy adults participated in this study. The kinematic and kinetic...

journal_title：Frontiers in neurology

authors： Mao YR,Wu XQ,Zhao JL,Lo WLA,Chen L,Ding MH,Xu ZQ,Bian RH,Huang DF,Li L

更新日期：2018-03-26 00:00:00

abstract：:Background: Matrix metalloproteinases (MMPs) are pleiotropic enzymes involved in extracellular protein degradation and turnover. MMPs are implicated in the pathogenesis of many neurological diseases, including multiple sclerosis (MS). Objective: To search the level of MMPs in the cerebrospinal fluid (CSF) of MS patien...

journal_title：Frontiers in neurology

authors： Castellazzi M,Ligi D,Contaldi E,Quartana D,Fonderico M,Borgatti L,Bellini T,Trentini A,Granieri E,Fainardi E,Mannello F,Pugliatti M

更新日期：2018-12-18 00:00:00

abstract：:Rhythmic auditory cueing is a well-accepted tool for gait rehabilitation in Parkinson's disease (PD), which can now be applied in a performance-adapted fashion due to technological advance. This study investigated the immediate differences on gait during a prolonged, 30 min, walk with performance-adapted (intelligent)...

journal_title：Frontiers in neurology

authors： Ginis P,Heremans E,Ferrari A,Dockx K,Canning CG,Nieuwboer A

更新日期：2017-04-06 00:00:00

abstract：:Introduction: Mutations in the Parkin gene are the most common cause of autosomal recessive early-onset Parkinson's disease (PD). However, little is known about the quality of life (QoL) in Parkin-related PD. Here, we investigated the patterns of QoL in newly diagnosed Parkin-related PD patients. Methods: Newly diagno...

journal_title：Frontiers in neurology

authors： Zhou XY,Liu FT,Chen C,Luo SS,Zhao J,Tang YL,Shen B,Yu WB,Zuo CT,Wu JJ,Ding ZT,Wang J,Sun YM

更新日期：2020-12-18 00:00:00

abstract：:We previously reported that persistent application of the non-specific cholinergic agonist carbachol (CAR) increased the frequency of calcium channel-mediated oscillatory activity in pedunculopontine nucleus (PPN) neurons, which we identified as dependent on voltage-gated, high-threshold P/Q-type channels. Here, we te...

journal_title：Frontiers in neurology

authors： Kezunovic N,Hyde J,Goitia B,Bisagno V,Urbano FJ,Garcia-Rill E

更新日期：2013-11-06 00:00:00

abstract：:Patients with epilepsy and treated with antiepileptic drugs (AEDs) may develop metabolic bone disease; however, the exact pathogenesis of bone loss with AEDs is still unclear. Included were 75 adults with epilepsy (mean age: 31.90 ± 5.62 years; duration of treatment with AEDs: 10.57 ± 3.55 years) and 40 matched health...

journal_title：Frontiers in neurology

authors： Hamed SA,Moussa EM,Youssef AH,Abd ElHameed MA,NasrEldin E

更新日期：2014-08-04 00:00:00

abstract：BACKGROUND:A possible link between 3D movies and headache (HA) has never been a target of specific and systematic investigations. The aim of this study was to investigate the relationship between 3D cinema and HA and to evaluate possible risk factors of developing HA during or after watching a 3D movie. METHODS:This w...

journal_title：Frontiers in neurology

authors： Braschinsky M,Raidvee A,Sabre L,Zmachinskaja N,Zukovskaja O,Karask A,Saar B,Rakitin A

更新日期：2016-03-23 00:00:00

abstract：:Neuroinflammation is one of the most important processes involved in the pathogenesis of Parkinson's disease (PD). The current concept of neuroinflammation comprises an inflammation process, which occurs in the central nervous system due to molecules released from brain-resident and/or blood-derived immune cells. Furt...

journal_title：Frontiers in neurology

authors： Troncoso-Escudero P,Parra A,Nassif M,Vidal RL

更新日期：2018-10-15 00:00:00

abstract：:Dizziness and imbalance are clinically poorly defined terms, which affect ~30% of people over 65 years of age. In these people, it is often difficult to define the primary cause of dizziness, as it can stem from cardiovascular, vestibular, psychological, and neuromuscular causes. However, identification of the primary...

journal_title：Frontiers in neurology

authors： Chau AT,Menant JC,Hübner PP,Lord SR,Migliaccio AA

更新日期：2015-12-24 00:00:00

abstract：Background:There is increasing interest in stem cell therapy as another treatment modality in stroke, particularly for patients who are unable to receive endovascular clot retrieval or thrombolysis therapies, or for whom standard treatment has failed. We have recently shown that human amniotic epithelial cells (hAECs) ...

journal_title：Frontiers in neurology

authors： Phan TG,Ma H,Lim R,Sobey CG,Wallace EM

更新日期：2018-06-07 00:00:00

abstract：Objective:We investigated the reliability and accuracy of a bedside diagnostic algorithm for patients presenting with vertigo/unsteadiness to the emergency department. Methods:We enrolled consecutive adult patients presenting with vertigo/unsteadiness at a tertiary hospital. STANDING, the acronym for the four-step alg...

journal_title：Frontiers in neurology

authors： Vanni S,Pecci R,Edlow JA,Nazerian P,Santimone R,Pepe G,Moretti M,Pavellini A,Caviglioli C,Casula C,Bigiarini S,Vannucchi P,Grifoni S

更新日期：2017-11-07 00:00:00

abstract：:In task-specific focal hand dystonia (tspFHD), the temporal dynamics of cortical activity in the motor system and how these processes are related to impairments in sensory and motor function are poorly understood. Here, we use time-frequency reconstructions of magnetoencephalographic (MEG) data to elaborate the tempor...

journal_title：Frontiers in neurology

authors： Hinkley LB,Dolberg R,Honma S,Findlay A,Byl NN,Nagarajan SS

更新日期：2012-11-28 00:00:00

abstract：:Approaches to furthering our understanding of the bioeffects, behavioral changes, and treatment options following exposure to blast are a worldwide priority. Of particular need is a more concerted effort to employ animal models to determine possible sex differences, which have been reported in the clinical literature....

journal_title：Frontiers in neurology

authors： McCabe JT,Tucker LB

更新日期：2020-09-30 00:00:00

abstract：:Fatigue is one of the most disabling side effects in people with multiple sclerosis. While this fact is well known, there has been a remarkable lack of progress in determining the pathophysiological mechanisms behind fatigue and the establishment of effective treatments. The main barrier has been the lack of a unified...

journal_title：Frontiers in neurology

authors： Rudroff T,Kindred JH,Ketelhut NB

更新日期：2016-08-02 00:00:00

abstract：:Background: Increasing evidence indicates that early radiation-induced subtle cerebral changes may be the precursors to permanent brain dysfunction at the late-delayed (LDS) post-radiotherapy (RT) stage. In this study, we aim to track the RT-related longitudinal brain activity in nasopharyngeal carcinoma (NPC) patient...

journal_title：Frontiers in neurology

authors： Yang Y,Lin X,Li J,Han L,Li Z,Liu S,Hou G,Xie C,Lv X,Qiu Y

更新日期：2019-07-16 00:00:00

abstract：:The purpose of the study was to test the utility of unique panel of blood biomarkers as a means to reflect one's recovery process after sport-related neurotrauma. We established a panel of biomarkers that reacted positive with CD81 (extracellular vesicle marker) and various neuron- and glia-specific antigens [e.g., ne...

journal_title：Frontiers in neurology

authors： Kawata K,Mitsuhashi M,Aldret R

更新日期：2018-04-12 00:00:00

abstract：:Purpose: Whole-brain functional network analysis is an emerging methodology for exploring the mechanisms underlying hepatic encephalopathy (HE). This study aimed to identify the brain subnetwork that is significantly altered within the functional connectome in minimal HE (MHE), the earliest stage of HE. Materials and ...

journal_title：Frontiers in neurology

authors： Zhan C,Chen HJ,Gao YQ,Zou TX

更新日期：2019-01-29 00:00:00

abstract：:Animal models of concussion, traumatic brain injury (TBI), and chronic traumatic encephalopathy (CTE) are widely available and routinely deployed in laboratories around the world. Effective animal modeling requires careful consideration of four basic principles. First, animal model use must be guided by clarity of def...

journal_title：Frontiers in neurology

authors： Wojnarowicz MW,Fisher AM,Minaeva O,Goldstein LE

更新日期：2017-06-01 00:00:00

abstract：:Huntington's disease (HD) is an autosomal dominant neurodegenerative genetic disorder characterized by motor, cognitive, and psychiatric symptoms. It is well established that regular physical activity supports brain health, benefiting cognitive function, mental health as well as brain structure and plasticity. Exercis...

journal_title：Frontiers in neurology

authors： Paré MF,Jasmin BJ

更新日期：2017-09-27 00:00:00

abstract：:Stroke is becoming one of the leading causes of adult disability and death in sub-Saharan African countries. The aim of the present study is to provide an up-to-date account of the clinical and demographic characteristics of patients with stroke admitted to the University of Gondar College of Medicine and Health Scien...

journal_title：Frontiers in neurology

authors： Baye M,Hintze A,Gordon-Murer C,Mariscal T,Belay GJ,Gebremariam AA,Hughes CML

更新日期：2020-05-19 00:00:00

abstract：:Background: Disorders of consciousness are challenging to diagnose, with inconsistent behavioral responses, motor and cognitive disabilities, leading to approximately 40% misdiagnoses. Heart rate variability (HRV) reflects the complexity of the heart-brain two-way dynamic interactions. HRV entropy analysis quantifies ...

journal_title：Frontiers in neurology

authors： Riganello F,Larroque SK,Bahri MA,Heine L,Martial C,Carrière M,Charland-Verville V,Aubinet C,Vanhaudenhuyse A,Chatelle C,Laureys S,Di Perri C

更新日期：2018-09-12 00:00:00

abstract：:Disrupted development of oropharyngeal structures as well as cranial nerve and brainstem circuits may lead to feeding and swallowing difficulties in children with 22q11. 2 deletion syndrome (22q11DS). We previously demonstrated aspiration-based dysphagia during early postnatal life in the LgDel mouse model of 22q11DS ...

journal_title：Frontiers in neurology

authors： Welby L,Caudill H,Yitsege G,Hamad A,Bunyak F,Zohn IE,Maynard T,LaMantia AS,Mendelowitz D,Lever TE

更新日期：2020-01-31 00:00:00

abstract：OBJECTIVE:(1) To determine the brain connectivity pattern associated with clinical rigidity scores in Parkinson's disease (PD) and (2) to determine the relation between clinically assessed rigidity and quantitative metrics of motor performance. BACKGROUND:Rigidity, the resistance to passive movement, is exacerbated in...

journal_title：Frontiers in neurology

authors： Baradaran N,Tan SN,Liu A,Ashoori A,Palmer SJ,Wang ZJ,Oishi MM,McKeown MJ

更新日期：2013-06-05 00:00:00

abstract：BACKGROUND:Parasympathetic innervation of meninges and ability of carbachol, acetylcholine (ACh) receptor (AChR) agonist, to induce headaches suggests contribution of cholinergic mechanisms to primary headaches. However, neurochemical mechanisms of cholinergic regulation of peripheral nociception in meninges, origin pl...

journal_title：Frontiers in neurology

authors： Shelukhina I,Mikhailov N,Abushik P,Nurullin L,Nikolsky EE,Giniatullin R

更新日期：2017-04-27 00:00:00

abstract：:Inflammatory myositis (IM) and myasthenia gravis (MG) are both immune disorders involving muscle. The concurrent presence of both conditions in the same patient is extremely rare and the diagnosis is important and challenging. Here, we report a case of concurrent myositis and myocarditis and MG without thymoma in a 69...

journal_title：Frontiers in neurology

authors： Zhou Z,Chen X,Liu G,Pu J,Wu J

更新日期：2019-07-16 00:00:00

abstract：:The persistent primitive hypoglossal artery (PPHA) is the second most common persistent carotid-vertebrobasilar anastomosis, with an incidence of 0.027-0.26%. PPHAs change the hemodynamics of the carotid and vertebrobasilar system and may be associated with intracranial vascular anomalies, but basilar bifurcation aneu...

journal_title：Frontiers in neurology

authors： Wang M,Gu J,Lan P,Wan S,Zhou Y,Zheng X,Zhan R

更新日期：2017-04-26 00:00:00

abstract：:Although ~50% of patients with Parkinson's disease (PD) experience depression, treatment for this important and debilitating comorbidity is relatively understudied. Deep brain stimulation (DBS) has been increasingly utilized for the management of tremors in progressive PD. Several preliminary studies have shown the po...

journal_title：Frontiers in neurology

authors： Gökbayrak NS,Piryatinsky I,Gavett RA,Ahmed OJ

更新日期：2014-08-11 00:00:00

abstract：BACKGROUND:Before implementation in clinical practice, biomarker assays need to be thoroughly analytically validated. There is currently a strong interest in implementation of the ratio of amyloid-β peptide 1-42 and 1-40 (Aβ42/Aβ40) in clinical routine. Therefore, in this study, we compared the analytical performance o...

journal_title：Frontiers in neurology

authors： van Waalwijk van Doorn LJC,Kulic L,Koel-Simmelink MJA,Kuiperij HB,Versleijen AAM,Struyfs H,Twaalfhoven HAM,Fourier A,Engelborghs S,Perret-Liaudet A,Lehmann S,Verbeek MM,Vanmechelen EJM,Teunissen CE

更新日期：2017-07-03 00:00:00

abstract：:Light impinging on the retina fulfils a dual function: it serves for vision and it is required for proper entrainment of the endogenous circadian timing system to the 24-h day, thus influencing behaviors that promote health and optimal quality of life but are independent of image formation. The circadian pacemaker loc...

journal_title：Frontiers in neurology

authors： Chellappa SL,Lasauskaite R,Cajochen C

更新日期：2017-10-20 00:00:00

abstract：:Hemiconvulsion-hemiplegia-epilepsy syndrome (HHE) is a rare outcome of prolonged hemiconvulsion that is followed by diffuse unilateral hemispheric edema, hemiplegia, and ultimately hemiatrophy of the affected hemisphere and epilepsy. Here, we describe the case of a 3-year-old male with a 1;3 translocation leading to a...

journal_title：Frontiers in neurology

authors： Robinson JE,Wolfe SM,Kaiser-Rogers K,Greenwood RS

更新日期：2016-05-04 00:00:00