Abstract:
:The histograms of response times of optimal YES/NO decisions that are computed from a single sensory Poisson neuron are highly structured. In particular, response times in NO decisions are quantized to a small set of times, while response times in YES decisions have a multimodal structure. Both the times of NO decisions, as well as the modes of the the histogram of YES decisions, are associated to the number of action potentials that were necessary to reach the decision. Their value is a function of the firing rate of the neuron in response to the states of the stimulus.
journal_name
Front Comput Neuroscijournal_title
Frontiers in computational neuroscienceauthors
Perona Pdoi
10.3389/fncom.2014.00042subject
Has Abstractpub_date
2014-04-11 00:00:00pages
42issn
1662-5188journal_volume
8pub_type
杂志文章abstract::Predictive coding appears to be one of the fundamental working principles of brain processing. Amongst other aspects, brains often predict the sensory consequences of their own actions. Predictive coding resembles Kalman filtering, where incoming sensory information is filtered to produce prediction errors for subsequ...
journal_title:Frontiers in computational neuroscience
pub_type: 杂志文章
doi:10.3389/fncom.2015.00047
更新日期:2015-04-30 00:00:00
abstract::The mechanisms underlying electrophysiologically observed two-way transitions between absence and tonic-clonic epileptic seizures in cerebral cortex remain unknown. The interplay within thalamocortical network is believed to give rise to these epileptic multiple modes of activity and transitions between them. In parti...
journal_title:Frontiers in computational neuroscience
pub_type: 杂志文章
doi:10.3389/fncom.2017.00059
更新日期:2017-07-07 00:00:00
abstract::We often encounter pairs of variables in the world whose mutual relationship can be described by a function. After training, human responses closely correspond to these functional relationships. Here we study how humans predict unobserved segments of a function that they have been trained on and we compare how human p...
journal_title:Frontiers in computational neuroscience
pub_type: 杂志文章
doi:10.3389/fncom.2014.00121
更新日期:2014-09-30 00:00:00
abstract::We present a high-capacity model for one-shot association learning (hetero-associative memory) in sparse networks. We assume that basic patterns are pre-learned in networks and associations between two patterns are presented only once and have to be learned immediately. The model is a combination of an Amit-Fusi like ...
journal_title:Frontiers in computational neuroscience
pub_type: 杂志文章
doi:10.3389/fncom.2014.00140
更新日期:2014-11-07 00:00:00
abstract::VISUAL RECEPTIVE FIELD (RF) ATTRIBUTES IN VISUAL CORTEX OF PRIMATES HAVE BEEN EXPLAINED MAINLY FROM CORTICAL CONNECTIONS: visual RFs progress from simple to complex through cortico-cortical pathways from lower to higher levels in the visual hierarchy. This feedforward flow of information is paired with top-down proces...
journal_title:Frontiers in computational neuroscience
pub_type: 杂志文章
doi:10.3389/fncom.2012.00029
更新日期:2012-05-28 00:00:00
abstract::Statistical models for describing the probability distribution over the states of biological systems are commonly used for dimensional reduction. Among these models, pairwise models are very attractive in part because they can be fit using a reasonable amount of data: knowledge of the mean values and correlations betw...
journal_title:Frontiers in computational neuroscience
pub_type: 杂志文章
doi:10.3389/neuro.10.022.2009
更新日期:2009-11-17 00:00:00
abstract::A vast amount of information about the external world continuously flows into the brain, whereas its capacity to process such information is limited. Attention enables the brain to allocate its resources of information processing to selected sensory inputs for reducing its computational load, and effects of attention ...
journal_title:Frontiers in computational neuroscience
pub_type: 杂志文章
doi:10.3389/fncom.2011.00031
更新日期:2011-07-08 00:00:00
abstract::The cerebellum is known to play a critical role in learning relevant patterns of activity for adaptive motor control, but the underlying network mechanisms are only partly understood. The classical long-term synaptic plasticity between parallel fibers (PFs) and Purkinje cells (PCs), which is driven by the inferior oli...
journal_title:Frontiers in computational neuroscience
pub_type: 杂志文章,评审
doi:10.3389/fncom.2014.00097
更新日期:2014-08-15 00:00:00
abstract::We address a question on the effect of common stochastic inputs on the correlation of the spike trains of two neurons when they are coupled through direct connections. We show that the change in the correlation of small amplitude stochastic inputs can be better detected when the neurons are connected by direct excitat...
journal_title:Frontiers in computational neuroscience
pub_type: 杂志文章
doi:10.3389/fncom.2013.00108
更新日期:2013-08-14 00:00:00
abstract::Head direction cells fire to signal the direction in which an animal's head is pointing. They are able to track head direction using only internally-derived information (path integration)In this simulation study we investigate the factors that affect path integration accuracy. Specifically, two major limiting factors ...
journal_title:Frontiers in computational neuroscience
pub_type: 杂志文章
doi:10.3389/fncom.2015.00010
更新日期:2015-02-06 00:00:00
abstract::The problem of cancer risk analysis is of great importance to health-service providers and medical researchers. In this study, we propose a novel Artificial Neural Network (ANN) algorithm based on the probabilistic framework, which aims to investigate patient patterns associated with their disease development. Compare...
journal_title:Frontiers in computational neuroscience
pub_type: 杂志文章
doi:10.3389/fncom.2020.00058
更新日期:2020-07-21 00:00:00
abstract::Neuron encodes and transmits information through generating sequences of output spikes, which is a high energy-consuming process. The spike is initiated when membrane depolarization reaches a threshold voltage. In many neurons, threshold is dynamic and depends on the rate of membrane depolarization (dV/dt) preceding a...
journal_title:Frontiers in computational neuroscience
pub_type: 杂志文章
doi:10.3389/fncom.2015.00062
更新日期:2015-05-27 00:00:00
abstract::Two important stimulus features represented within the rodent barrel cortex are velocity and angular direction of whisker deflection. Each cortical barrel receives information from thalamocortical (TC) cells that relay information from a single whisker, and TC input is decoded by barrel regular-spiking (RS) cells thro...
journal_title:Frontiers in computational neuroscience
pub_type: 杂志文章
doi:10.3389/fncom.2018.00045
更新日期:2018-06-12 00:00:00
abstract::With the emergence of online publishing, opportunities to maximize transparency of scientific research have grown considerably. However, these possibilities are still only marginally used. We argue for the implementation of (1) peer-reviewed peer review, (2) transparent editorial hierarchies, and (3) online data publi...
journal_title:Frontiers in computational neuroscience
pub_type: 杂志文章
doi:10.3389/fncom.2012.00020
更新日期:2012-04-03 00:00:00
abstract::To understand the function of the neocortex, which is a hierarchical distributed network, it is useful giving meaning to the signals transmitted between these areas from the computational viewpoint. The overall anatomical structure or organs related to this network, including the neocortex, thalamus, and basal ganglia...
journal_title:Frontiers in computational neuroscience
pub_type: 杂志文章
doi:10.3389/fncom.2020.00074
更新日期:2020-08-18 00:00:00
abstract::Neuronal networks exhibit a wide diversity of structures, which contributes to the diversity of the dynamics therein. The presented work applies an information theoretic framework to simultaneously analyze structure and dynamics in neuronal networks. Information diversity within the structure and dynamics of a neurona...
journal_title:Frontiers in computational neuroscience
pub_type: 杂志文章
doi:10.3389/fncom.2011.00026
更新日期:2011-06-01 00:00:00
abstract::Despite an abundance of computational models for learning of synaptic weights, there has been relatively little research on structural plasticity, i.e., the creation and elimination of synapses. Especially, it is not clear how structural plasticity works in concert with spike-timing-dependent plasticity (STDP) and wha...
journal_title:Frontiers in computational neuroscience
pub_type: 杂志文章
doi:10.3389/fncom.2016.00093
更新日期:2016-09-08 00:00:00
abstract::Over the last decade robotics has attracted a great deal of interest from teachers and researchers as a valuable educational tool from preschool to highschool levels. The implementation of social-support behaviors in robot tutors, in particular in the emotional dimension, can make a significant contribution to learnin...
journal_title:Frontiers in computational neuroscience
pub_type: 杂志文章
doi:10.3389/fncom.2016.00077
更新日期:2016-08-03 00:00:00
abstract::Cortical neurons are typically driven by several thousand synapses. The precise spatiotemporal pattern formed by these inputs can modulate the response of a post-synaptic cell. In this work, we explore how the temporal structure of pre-synaptic inhibitory and excitatory inputs impact the post-synaptic firing of a cond...
journal_title:Frontiers in computational neuroscience
pub_type: 杂志文章
doi:10.3389/fncom.2011.00060
更新日期:2011-12-16 00:00:00
abstract::Synchrony and asynchrony are essential aspects of the functioning of interconnected neuronal cells and networks. New information on neuronal synchronization can be expected to aid in understanding these systems. Synchronization provides insight in the functional connectivity and the spatial distribution of the informa...
journal_title:Frontiers in computational neuroscience
pub_type: 杂志文章
doi:10.3389/fncom.2016.00112
更新日期:2016-10-18 00:00:00
abstract::A neural code based on sequences of spikes can consume a significant portion of the brain's energy budget. Thus, energy considerations would dictate that spiking activity be kept as low as possible. However, a high spike-rate improves the coding and representation of signals in spike trains, particularly in sensory sy...
journal_title:Frontiers in computational neuroscience
pub_type: 杂志文章
doi:10.3389/fncom.2015.00061
更新日期:2015-06-02 00:00:00
abstract::In temporal lobe epilepsy (TLE), the variation of chemical receptor expression underlies the basis of neural network activity shifts, resulting in neuronal hyperexcitability and epileptiform discharges. However, dynamical mechanisms involved in the transitions of TLE are not fully understood, because of the neuronal d...
journal_title:Frontiers in computational neuroscience
pub_type: 杂志文章
doi:10.3389/fncom.2017.00061
更新日期:2017-07-11 00:00:00
abstract::Visual appearance of natural objects is profoundly affected by viewing conditions such as viewpoint and illumination. Human subjects can nevertheless compensate well for variations in these viewing conditions. The strategies that the visual system uses to accomplish this are largely unclear. Previous computational stu...
journal_title:Frontiers in computational neuroscience
pub_type: 杂志文章
doi:10.3389/fncom.2012.00056
更新日期:2012-08-24 00:00:00
abstract::Astrocytes actively shape the dynamics of neurons and neuronal ensembles by affecting several aspects critical to neuronal function, such as regulating synaptic plasticity, modulating neuronal excitability, and maintaining extracellular ion balance. These pathways for astrocyte-neuron interaction can also enhance the ...
journal_title:Frontiers in computational neuroscience
pub_type: 杂志文章
doi:10.3389/fncom.2012.00058
更新日期:2012-08-13 00:00:00
abstract::In vivo and in vitro experimental studies have found that blocking electrical interactions connecting GABAergic interneurons reduces oscillatory activity in the gamma range in cortex. However, recent theoretical works have shown that the ability of electrical synapses to promote or impede synchrony, when alone, depend...
journal_title:Frontiers in computational neuroscience
pub_type: 杂志文章
doi:10.3389/neuro.10.008.2007
更新日期:2007-11-02 00:00:00
abstract::The motor system generates time-varying commands to move our limbs and body. Conventional descriptions of motor control and learning rely on dynamical representations of our body's state (forward and inverse models), and control policies that must be integrated forward to generate feedforward time-varying commands; th...
journal_title:Frontiers in computational neuroscience
pub_type: 杂志文章
doi:10.3389/fncom.2015.00032
更新日期:2015-03-19 00:00:00
abstract::The striatum is an important subcortical structure with extensive connections to other regions of the brain. These connections are believed to play important roles in behaviors such as reward-related processes and impulse control, which show significant sex differences. However, little is known about sex differences i...
journal_title:Frontiers in computational neuroscience
pub_type: 杂志文章
doi:10.3389/fncom.2016.00100
更新日期:2016-09-23 00:00:00
abstract::This paper presents a new model-based method to define muscle synergies. Unlike the conventional factorization approach, which extracts synergies from electromyographic data, the proposed method employs a biomechanical model and formally defines the synergies as the solution of an optimal control problem. As a result,...
journal_title:Frontiers in computational neuroscience
pub_type: 杂志文章
doi:10.3389/fncom.2015.00121
更新日期:2015-10-06 00:00:00
abstract::Neuronal networks in rodent barrel cortex are characterized by stable low baseline firing rates. However, they are sensitive to the action potentials of single neurons as suggested by recent single-cell stimulation experiments that reported quantifiable behavioral responses in response to short spike trains elicited i...
journal_title:Frontiers in computational neuroscience
pub_type: 杂志文章
doi:10.3389/fncom.2013.00156
更新日期:2013-11-07 00:00:00
abstract::The human brain is a complex system composed by several large scale intrinsic networks with distinct functions. The low frequency oscillation (LFO) signal of blood oxygen level dependent (BOLD), measured through resting-state fMRI, reflects the spontaneous neural activity of these networks. We propose to characterize ...
journal_title:Frontiers in computational neuroscience
pub_type: 杂志文章
doi:10.3389/fncom.2018.00064
更新日期:2018-08-03 00:00:00