Information diversity in structure and dynamics of simulated neuronal networks.

abstract：:Neuron encodes and transmits information through generating sequences of output spikes, which is a high energy-consuming process. The spike is initiated when membrane depolarization reaches a threshold voltage. In many neurons, threshold is dynamic and depends on the rate of membrane depolarization (dV/dt) preceding a...

journal_title：Frontiers in computational neuroscience

authors： Yi GS,Wang J,Tsang KM,Wei XL,Deng B

更新日期：2015-05-27 00:00:00

abstract：:Biological realism of dendritic morphologies is important for simulating electrical stimulation of brain tissue. By adding point process modeling and conditional sampling to existing generation strategies, we provide a novel means of reproducing the nuanced branching behavior that occurs in different layers of granule...

journal_title：Frontiers in computational neuroscience

authors： Chou ZZ,Yu GJ,Berger TW

更新日期：2020-04-09 00:00:00

abstract：:The motor system generates time-varying commands to move our limbs and body. Conventional descriptions of motor control and learning rely on dynamical representations of our body's state (forward and inverse models), and control policies that must be integrated forward to generate feedforward time-varying commands; th...

journal_title：Frontiers in computational neuroscience

authors： Berniker M,Kording KP

更新日期：2015-03-19 00:00:00

abstract：:The mechanisms underlying electrophysiologically observed two-way transitions between absence and tonic-clonic epileptic seizures in cerebral cortex remain unknown. The interplay within thalamocortical network is believed to give rise to these epileptic multiple modes of activity and transitions between them. In parti...

journal_title：Frontiers in computational neuroscience

authors： Fan D,Duan L,Wang Q,Luan G

更新日期：2017-07-07 00:00:00

abstract：:Recently, biologically inspired models are gradually proposed to solve the problem in text analysis. Convolutional neural networks (CNN) are hierarchical artificial neural networks, which include a various of multilayer perceptrons. According to biological research, CNN can be improved by bringing in the attention mod...

journal_title：Frontiers in computational neuroscience

authors： Fu H,Niu Z,Zhang C,Ma J,Chen J

更新日期：2016-07-14 00:00:00

abstract：:Scientific research produces new knowledge, technologies, and clinical treatments that can lead to enormous returns. Often, the path from basic research to new paradigms and direct impact on society takes time. Precise quantification of scientific output in the short-term is not an easy task but is critical for evalua...

journal_title：Frontiers in computational neuroscience

authors： Kreiman G,Maunsell JH

更新日期：2011-11-10 00:00:00

abstract：:Statistical learning is a learning mechanism based on transition probability in sequences such as music and language. Recent computational and neurophysiological studies suggest that the statistical learning contributes to production, action, and musical creativity as well as prediction and perception. The present stu...

journal_title：Frontiers in computational neuroscience

authors： Daikoku T

更新日期：2019-10-02 00:00:00

abstract：:Deep brain stimulation (DBS) leads with radially distributed electrodes have potential to improve clinical outcomes through more selective targeting of pathways and networks within the brain. However, increasing the number of electrodes on clinical DBS leads by replacing conventional cylindrical shell electrodes with ...

journal_title：Frontiers in computational neuroscience

authors： Teplitzky BA,Zitella LM,Xiao Y,Johnson MD

更新日期：2016-06-10 00:00:00

abstract：:We describe a model for cortical development that resolves long-standing difficulties of earlier models. It is proposed that, during embryonic development, synchronous firing of neurons and their competition for limited metabolic resources leads to selection of an array of neurons with ultra-small-world characteristic...

journal_title：Frontiers in computational neuroscience

authors： Wright JJ,Bourke PD

更新日期：2013-02-15 00:00:00

abstract：:Persistent activity observed during delayed-response tasks for spatial working memory (Funahashi et al., 1989) has commonly been modeled by recurrent networks whose dynamics is described as a bump attractor (Compte et al., 2000). We examine the effects of interareal architecture on the dynamics of bump attractors in s...

journal_title：Frontiers in computational neuroscience

authors： Kilpatrick ZP

更新日期：2013-07-01 00:00:00

abstract：:Head direction cells fire to signal the direction in which an animal's head is pointing. They are able to track head direction using only internally-derived information (path integration)In this simulation study we investigate the factors that affect path integration accuracy. Specifically, two major limiting factors ...

journal_title：Frontiers in computational neuroscience

authors： Page HJ,Walters D,Stringer SM

更新日期：2015-02-06 00:00:00

abstract：:Molecular switches, such as the protein kinase CaMKII, play a fundamental role in cell signaling by decoding inputs into either high or low states of activity; because the high activation state can be turned on and persist after the input ceases, these switches have earned a reputation as "digital." Although this on/o...

journal_title：Frontiers in computational neuroscience

authors： Clarke SE

更新日期：2018-11-22 00:00:00

abstract：:Pitch is a perceptual correlate of periodicity. Sounds with distinct spectra can elicit the same pitch. Despite the importance of pitch perception, understanding the cellular mechanism of pitch perception is still a major challenge and a mechanistic model of pitch is lacking. A multi-stage neuronal network model is de...

journal_title：Frontiers in computational neuroscience

authors： Huang C,Rinzel J

更新日期：2016-06-16 00:00:00

abstract：:Brain computer interfaces allow users to preform various tasks using only the electrical activity of the brain. BCI applications often present the user a set of stimuli and record the corresponding electrical response. The BCI algorithm will then have to decode the acquired brain response and perform the desired task....

journal_title：Frontiers in computational neuroscience

authors： Manor R,Mishali L,Geva AB

更新日期：2016-12-20 00:00:00

abstract：:The human brain is a complex system composed by several large scale intrinsic networks with distinct functions. The low frequency oscillation (LFO) signal of blood oxygen level dependent (BOLD), measured through resting-state fMRI, reflects the spontaneous neural activity of these networks. We propose to characterize ...

journal_title：Frontiers in computational neuroscience

authors： Qi S,Gao Q,Shen J,Teng Y,Xie X,Sun Y,Wu J

更新日期：2018-08-03 00:00:00

abstract：:Short-term synaptic plasticity is highly diverse across brain area, cortical layer, cell type, and developmental stage. Since short-term plasticity (STP) strongly shapes neural dynamics, this diversity suggests a specific and essential role in neural information processing. Therefore, a correct characterization of sho...

journal_title：Frontiers in computational neuroscience

authors： Costa RP,Sjöström PJ,van Rossum MC

更新日期：2013-06-06 00:00:00

abstract：:Cortical neurons are typically driven by several thousand synapses. The precise spatiotemporal pattern formed by these inputs can modulate the response of a post-synaptic cell. In this work, we explore how the temporal structure of pre-synaptic inhibitory and excitatory inputs impact the post-synaptic firing of a cond...

journal_title：Frontiers in computational neuroscience

authors： Scheller B,Castellano M,Vicente R,Pipa G

更新日期：2011-12-16 00:00:00

abstract：:Many of the synapses in the basal ganglia display short-term plasticity. Still, computational models have not yet been used to investigate how this affects signaling. Here we use a model of the basal ganglia network, constrained by available data, to quantitatively investigate how synaptic short-term plasticity affect...

journal_title：Frontiers in computational neuroscience

authors： Lindahl M,Kamali Sarvestani I,Ekeberg O,Kotaleski JH

更新日期：2013-06-19 00:00:00

abstract：:Single-unit measurements have reported many different effects of attention on contrast-response (e.g., contrast-gain, response-gain, additive-offset dependent on visibility), while functional imaging measurements have more uniformly reported increases in response across all contrasts (additive-offset). The normalizati...

journal_title：Frontiers in computational neuroscience

authors： Hara Y,Pestilli F,Gardner JL

更新日期：2014-02-19 00:00:00

abstract：:Objective: To study the effect of directional deep brain stimulation (DBS) electrode configuration and vertical electrode spacing on the volume of tissue activated (VTA) in the globus pallidus, pars interna (GPi). Background: Directional DBS leads may allow clinicians to precisely direct current fields to different fu...

journal_title：Frontiers in computational neuroscience

authors： Zhang S,Tagliati M,Pouratian N,Cheeran B,Ross E,Pereira E

更新日期：2020-09-25 00:00:00

abstract：:Spatio-temporal brain activities with variable delay detectable in resting-state functional magnetic resonance imaging (rs-fMRI) give rise to highly reproducible structures, termed cortical lag threads, that propagate from one brain region to another. Using a computational topology of data approach, we found that pers...

journal_title：Frontiers in computational neuroscience

authors： Don APH,Peters JF,Ramanna S,Tozzi A

更新日期：2020-04-22 00:00:00

abstract：:What are the functional neuroimaging measurements required for more fully characterizing the events and locations of neocortical activity? A prime assumption has been that modulation of cortical activity will inevitably be reflected in changes in energy utilization (for the most part) changes of glucose and oxygen con...

journal_title：Frontiers in computational neuroscience

authors： Robinson SE,Mandell AJ,Coppola R

更新日期：2013-01-24 00:00:00

abstract：:Synaptic transmission is both history-dependent and stochastic, resulting in varying responses to presentations of the same presynaptic stimulus. This complicates attempts to infer synaptic parameters and has led to the proposal of a number of different strategies for their quantification. Recently Bayesian approaches...

journal_title：Frontiers in computational neuroscience

authors： Bird AD,Wall MJ,Richardson MJ

更新日期：2016-11-25 00:00:00

abstract：:In order to be able to examine the extracellular potential's influence on network activity and to better understand dipole properties of the extracellular potential, we present and analyze a three-dimensional formulation of the cable equation which facilitates numeric simulations. When the neuron's intra- and extracel...

journal_title：Frontiers in computational neuroscience

authors： Xylouris K,Wittum G

更新日期：2015-07-17 00:00:00

abstract：:Drosophila larvae crawl by peristaltic waves of muscle contractions, which propagate along the animal body and involve the simultaneous contraction of the left and right side of each segment. Coordinated propagation of contraction does not require sensory input, suggesting that movement is generated by a central patte...

journal_title：Frontiers in computational neuroscience

authors： Gjorgjieva J,Berni J,Evers JF,Eglen SJ

更新日期：2013-04-04 00:00:00

abstract：:The inverse problem for estimating model parameters from brain spike data is an ill-posed problem because of a huge mismatch in the system complexity between the model and the brain as well as its non-stationary dynamics, and needs a stochastic approach that finds the most likely solution among many possible solutions...

journal_title：Frontiers in computational neuroscience

authors： Hoang H,Yamashita O,Tokuda IT,Sato MA,Kawato M,Toyama K

更新日期：2015-05-21 00:00:00

abstract：:Dynamics of a homogeneous neural population interacting with active extracellular medium were considered. The corresponding mathematical model was tuned specifically to describe the behavior of interneurons with tonic GABA conductance under the action of non-stationary ambient GABA. The feedback provided by the GABA m...

journal_title：Frontiers in computational neuroscience

authors： Adamchik DA,Matrosov VV,Kazantsev VB

更新日期：2018-04-05 00:00:00

abstract：:Relatively recent advances in patch clamp recordings and iontophoresis have enabled unprecedented study of neuronal post-synaptic integration ("dendritic integration"). Findings support a separate layer of integration in the dendritic branches before potentials reach the cell's soma. While integration between branches...

journal_title：Frontiers in computational neuroscience

authors： Singh MF,Zald DH

更新日期：2015-08-10 00:00:00

abstract：:Cooperation and competition, as two common and opposite examples of interpersonal dynamics, are thought to be reflected by different cognitive, neural, and behavioral patterns. According to the conventional approach, they have been explored by measuring subjects' reactions during individual performance or turn-based i...

journal_title：Frontiers in computational neuroscience

authors： Balconi M,Vanutelli ME

更新日期：2017-09-29 00:00:00

abstract：:The study of sensory signaling in the visual cortex has been greatly advanced by the recording of neural activity simultaneously with the performance of a specific psychophysical task. Individual nerve cells may also increase their firing leading up to the particular choice or decision made on a single psychophysical ...

journal_title：Frontiers in computational neuroscience

authors： Parker AJ

更新日期：2013-08-13 00:00:00