Anti-Anisakis IgE seroprevalence in the healthy Croatian coastal population and associated risk factors.

abstract：BACKGROUND:Though Nepal declared leprosy elimination in 2010, its burden is constantly rising in Terai communities for the past 2 years with 3000 new leprosy cases being diagnosed annually. Community's perception is important for prevention and control of leprosy and enhancing quality of life of leprosy patients. Poor ...

journal_title：PLoS neglected tropical diseases

authors： Singh R,Singh B,Mahato S

更新日期：2019-01-11 00:00:00

abstract：:Dengue, a vector-borne disease spread by Aedes mosquitoes, is a global threat. In the absence of an efficacious dengue vaccine, vector control is the key intervention tool in Singapore. A good understanding of vector habitats is essential to formulate operational strategies. We examined the distribution, long-term tre...

journal_title：PLoS neglected tropical diseases

authors： Rajarethinam J,Ong J,Neo ZW,Ng LC,Aik J

更新日期：2020-04-20 00:00:00

abstract：BACKGROUND:The control of neglected tropical diseases (NTDs) has primarily focused on preventive chemotherapy and case management. Less attention has been placed on the role of ensuring access to adequate water, sanitation, and hygiene and personal preventive measures in reducing exposure to infection. Our aim was to a...

journal_title：PLoS neglected tropical diseases

authors： Tomczyk S,Deribe K,Brooker SJ,Clark H,Rafique K,Knopp S,Utzinger J,Davey G

更新日期：2014-11-13 00:00:00

abstract：:Mycetoma is considered a neglected tropical disease globally. However, data on its burden and the associated complications in Uganda are limited. Hence we aimed to estimate its burden in Uganda. Firstly, a systematic PubMed search for all studies of any design on mycetoma in Uganda without restriction to the year of p...

journal_title：PLoS neglected tropical diseases

authors： Kwizera R,Bongomin F,Meya DB,Denning DW,Fahal AH,Lukande R

更新日期：2020-04-29 00:00:00

abstract：BACKGROUND:A Global Programme to Eliminate Lymphatic Filariasis was launched in 2000, with mass drug administration (MDA) as the core strategy of the programme. After completing 13 years of operations through 2012 and with MDA in place in 55 of 73 endemic countries, the impact of the MDA programme on microfilaraemia, h...

journal_title：PLoS neglected tropical diseases

authors： Ramaiah KD,Ottesen EA

更新日期：2014-11-20 00:00:00

abstract：BACKGROUND:Leishmaniasis is a serious multifactorial parasitic disease with limited treatment options. Current chemotherapy is mainly consisted of drugs with serious drawbacks such as toxicity, variable efficacy and resistance. Alternative bioactive phytocompounds may provide a promising source for discovering new anti...

journal_title：PLoS neglected tropical diseases

authors： Karampetsou K,Koutsoni OS,Gogou G,Angelis A,Skaltsounis LA,Dotsika E

更新日期：2021-01-11 00:00:00

abstract：BACKGROUND:In the Americas, leishmaniasis is endemic in 18 countries, and from 2001 through 2015, 17 countries reported 843,931 cases of cutaneous and mucocutaneous leishmaniasis, and 12 countries reported 52,176 cases of visceral leishmaniasis. A Regional Information System (SisLeish) was created in order to provide k...

journal_title：PLoS neglected tropical diseases

authors： Maia-Elkhoury ANS,O B Valadas SY,Puppim-Buzanovsky L,Rocha F,Sanchez-Vazquez MJ

更新日期：2017-09-05 00:00:00

abstract：BACKGROUND:Schistosomiasis remains a global public health challenge, with 93% of the ~237 million infections occurring in sub-Saharan Africa. Though rarely fatal, its recurring nature makes it a lifetime disorder with significant chronic health burdens. Much of its negative health impact is due to non-specific conditio...

journal_title：PLoS neglected tropical diseases

authors： Terer CC,Bustinduy AL,Magtanong RV,Muhoho N,Mungai PL,Muchiri EM,Kitron U,King CH,Mutuku FM

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Visceral leishmaniasis (VL) or Kala-azar has been a major public health problem in Bihar, India, for several decades. A few VL infected districts including Vaishali have reported >600 cases annually. Hence, in 2015, the Government of India entrusted ICMR-Rajendra Memorial Research Institute of Medical Scienc...

journal_title：PLoS neglected tropical diseases

authors： Kumar V,Mandal R,Das S,Kesari S,Dinesh DS,Pandey K,Das VR,Topno RK,Sharma MP,Dasgupta RK,Das P

更新日期：2020-05-04 00:00:00

abstract：:The circulation of vector-borne zoonotic viruses is largely determined by the overlap in the geographical distributions of virus-competent vectors and reservoir hosts. What is less clear are the factors influencing the distribution of virus-specific lineages. Japanese encephalitis virus (JEV) is the most important eti...

journal_title：PLoS neglected tropical diseases

authors： Schuh AJ,Ward MJ,Brown AJ,Barrett AD

更新日期：2013-08-29 00:00:00

abstract：:Snakebites are a major Collective Health problem worldwide. In Brazil, Bothrops jararaca snake venom (BjV) evokes hemostatic disturbances, bleeding manifestations, and redox status imbalance. Specific antivenom therapy, although efficacious to revert most snakebite-induced manifestations, is incapable of treating seco...

journal_title：PLoS neglected tropical diseases

authors： Sachetto ATA,Rosa JG,Santoro ML

更新日期：2018-10-11 00:00:00

abstract：:Eukaryotes, protozoan, and helminth parasites make extensive use of protein kinases to control cellular functions, suggesting that protein kinases may represent novel targets for the development of anti-parasitic drugs. Because of their central role in intracellular signaling pathways, cyclic nucleotide-dependent kina...

journal_title：PLoS neglected tropical diseases

authors： Swierczewski BE,Davies SJ

更新日期：2009-08-25 00:00:00

abstract：BACKGROUND:Transmission of dengue virus (DENV) from humans to mosquitoes represents a critical component of dengue epidemiology. Examinations of this process have generally been hampered by a lack of methods that adequately represent natural acquisition of DENV by mosquitoes from humans. In this study, we assessed arti...

journal_title：PLoS neglected tropical diseases

authors： Long KC,Sulca J,Bazan I,Astete H,Jaba HL,Siles C,Kocher C,Vilcarromero S,Schwarz J,Escobedo-Vargas KS,Castro-Llanos F,Angulo L,Flores G,Ramal-Asayag C,Halsey ES,Hontz RD,Paz-Soldan VA,Scott TW,Lambrechts L,Morrison

更新日期：2019-02-12 00:00:00

abstract：:Rabies virus kills tens of thousands of people globally each year, especially in resource-limited countries. Yet, there are genetically- and antigenically-related lyssaviruses, all capable of causing the disease rabies, circulating globally among bats without causing conspicuous disease outbreaks. The species richness...

journal_title：PLoS neglected tropical diseases

authors： Hayman DT,Fooks AR,Marston DA,Garcia-R JC

更新日期：2016-12-30 00:00:00

abstract：:Filoviruses such as Ebola virus (EBOV) cause outbreaks of viral hemorrhagic fevers for which no FDA-approved vaccines or drugs are available. The 2014-2016 EBOV outbreak in West Africa infected approximately 30,000 people, killing more than 11,000 and affecting thousands more in areas still suffering from the effects ...

journal_title：PLoS neglected tropical diseases

authors： Haun BK,Kamara V,Dweh AS,Garalde-Machida K,Forkay SSE,Takaaze M,Namekar M,Wong TAS,Bell-Gam Woto AER,Humphreys P,Weeks OI,Fallah MP,Berestecky JM,Nerurkar VR,Lehrer AT

更新日期：2019-07-22 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Hookworm infection is among the major causes of anaemia in poor communities, but its importance in causing maternal anaemia is poorly understood, and this has hampered effective lobbying for the inclusion of anthelmintic treatment in maternal health packages. We sought to review existing evide...

journal_title：PLoS neglected tropical diseases

authors： Brooker S,Hotez PJ,Bundy DA

更新日期：2008-09-17 00:00:00

abstract：BACKGROUND:During the 2014-2016 West Africa Ebola Virus Disease (EVD) epidemic, the public health community had concerns that sexual transmission of the Ebola virus (EBOV) from EVD survivors was a risk, due to EBOV persistence in body fluids of EVD survivors, particularly semen. The Sierra Leone Ebola Virus Persistence...

journal_title：PLoS neglected tropical diseases

authors： Abad N,Malik T,Ariyarajah A,Ongpin P,Hogben M,McDonald SLR,Marrinan J,Massaquoi T,Thorson A,Ervin E,Bernstein K,Ross C,Liu WJ,Kroeger K,Durski KN,Broutet N,Knust B,Deen GF,Sierra Leone Ebola Virus Persistence Study Gr

更新日期：2017-09-11 00:00:00

abstract：BACKGROUND:The initial response to Leishmania parasites is essential in determining disease development or resistance. In vitro, a divergent response to Leishmania, characterized by high or low IFN-γ production has been described as a potential tool to predict both vaccine response and disease susceptibility in vivo. ...

journal_title：PLoS neglected tropical diseases

authors： Carneiro MW,Fukutani KF,Andrade BB,Curvelo RP,Cristal JR,Carvalho AM,Barral A,Van Weyenbergh J,Barral-Netto M,de Oliveira CI

更新日期：2016-11-21 00:00:00

abstract：BACKGROUND:In the Brazilian Amazon, clinical and epidemiological frameworks of Chagas disease are very dissimilar in relation to the endemic classical areas of transmission, possibly due to genetic and biological characteristics of the circulating Trypanosoma cruzi stocks. Twenty six T. cruzi stocks from Western Amazon...

journal_title：PLoS neglected tropical diseases

authors： Monteiro WM,Margioto Teston AP,Gruendling AP,dos Reis D,Gomes ML,de Araújo SM,Bahia MT,Magalhães LK,de Oliveira Guerra JA,Silveira H,Toledo MJ,Vale Barbosa Md

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Salmonella enterica serovar Typhi is transmitted by fecally contaminated food and water and causes approximately 22 million typhoid fever infections worldwide each year. Most cases occur in developing countries, where approximately 4% of patients develop intestinal perforation (IP). In Kasese District, Ugand...

journal_title：PLoS neglected tropical diseases

authors： Walters MS,Routh J,Mikoleit M,Kadivane S,Ouma C,Mubiru D,Mbusa B,Murangi A,Ejoku E,Rwantangle A,Kule U,Lule J,Garrett N,Halpin J,Maxwell N,Kagirita A,Mulabya F,Makumbi I,Freeman M,Joyce K,Hill V,Downing R,Mint

更新日期：2014-03-06 00:00:00

abstract：BACKGROUND:Lymphatic filariasis (LF) is a so-called neglected tropical disease, currently overshadowed by higher-profile efforts to address malaria, tuberculosis, and HIV/AIDS. Despite recent successes in arresting transmission, some 40 million people who already have the disease have been largely neglected. This study...

journal_title：PLoS neglected tropical diseases

authors： Perera M,Whitehead M,Molyneux D,Weerasooriya M,Gunatilleke G

更新日期：2007-11-21 00:00:00

abstract：:Genomic data generated from clinical Vibrio cholerae O1 isolates collected over a five year period in an area of Kolkata, India with seasonal cholera outbreaks allowed a detailed genetic analysis of serotype switching that occurred from Ogawa to Inaba and back to Ogawa. The change from Ogawa to Inaba resulted from mut...

journal_title：PLoS neglected tropical diseases

authors： Karlsson SL,Thomson N,Mutreja A,Connor T,Sur D,Ali M,Clemens J,Dougan G,Holmgren J,Lebens M

更新日期：2016-10-05 00:00:00

abstract：BACKGROUND:Yellow fever is endemic in some countries in Africa, and Aedes aegpyti is one of the most important vectors implicated in the outbreak. The mapping of the nation-wide distribution and the detection of insecticide resistance of vector mosquitoes will provide the beneficial information for forecasting of dengu...

journal_title：PLoS neglected tropical diseases

authors： Kawada H,Higa Y,Futami K,Muranami Y,Kawashima E,Osei JH,Sakyi KY,Dadzie S,de Souza DK,Appawu M,Ohta N,Suzuki T,Minakawa N

更新日期：2016-06-15 00:00:00

abstract：BACKGROUND:Urinary Schistosomiasis is a neglected tropical disease endemic in many sub Saharan -African countries. Collectin Kidney 1 (CL-K1, encoded by COLEC11 on chromosome 2p25.3), a member of the vertebrate C-type lectin super family, has recently been identified as pattern-recognition molecule (PRR) of the lectin ...

journal_title：PLoS neglected tropical diseases

authors： Antony JS,Ojurongbe O,Kremsner PG,Velavan TP

更新日期：2015-03-25 00:00:00

abstract：:Most treatments of leishmaniasis require hospitalization and present side effects or parasite resistance; innovations in drug formulation/reposition can overcome these barriers and must be pursued to increase therapeutic alternatives. Therefore, we tested polymyxin B (polB) potential to kill Leishmania amazonensis, ad...

journal_title：PLoS neglected tropical diseases

authors： Souza Ribeiro Costa J,Medeiros M,Yamashiro-Kanashiro EH,Rocha MC,Cotrim PC,Stephano MA,Lancellotti M,Tavares GD,Oliveira-Nascimento L

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:The caterpillar of the moth Premolis semirufa (Lepidoptera: Arctiidae), commonly named Pararama, is endemic of the Amazon basin. Accidental contact with these caterpillar bristles causes local symptoms such as intense heat, pain, edema and itching which last for three to seven days; however, after multiples ...

journal_title：PLoS neglected tropical diseases

authors： Villas-Boas IM,Gonçalves-de-Andrade RM,Pidde-Queiroz G,Assaf SL,Portaro FC,Sant'Anna OA,van den Berg CW,Tambourgi DV

更新日期：2012-01-01 00:00:00

abstract：:Response to Zika virus (ZIKV) invasion in Brazil lagged a year from its estimated February 2014 introduction, and was triggered by the occurrence of severe congenital malformations. Dengue (DENV) and chikungunya (CHIKV) invasions tend to show similar response lags. We analyzed geo-coded symptomatic case reports from t...

journal_title：PLoS neglected tropical diseases

authors： Bisanzio D,Dzul-Manzanilla F,Gomez-Dantés H,Pavia-Ruz N,Hladish TJ,Lenhart A,Palacio-Vargas J,González Roldan JF,Correa-Morales F,Sánchez-Tejeda G,Kuri Morales P,Manrique-Saide P,Longini IM,Halloran ME,Vazquez-Prokopec GM

更新日期：2018-03-15 00:00:00

abstract：BACKGROUND:Primary infection of Toxoplasma gondii during pregnancy can be transmitted to the unborn child and may have serious consequences, including retinochoroiditis, hydrocephaly, cerebral calcifications, encephalitis, splenomegaly, hearing loss, blindness, and death. Austria, a country with moderate seroprevalence...

journal_title：PLoS neglected tropical diseases

authors： Prusa AR,Kasper DC,Sawers L,Walter E,Hayde M,Stillwaggon E

更新日期：2017-07-10 00:00:00

abstract：BACKGROUND:The factors influencing variation in the clinical forms of Chagas disease have not been elucidated; however, it is likely that the genetics of both the host and the parasite are involved. Several studies have attempted to correlate the T. cruzi strains involved in infection with the clinical forms of the dis...

journal_title：PLoS neglected tropical diseases

authors： Mendes TA,Reis Cunha JL,de Almeida Lourdes R,Rodrigues Luiz GF,Lemos LD,dos Santos AR,da Câmara AC,Galvão LM,Bern C,Gilman RH,Fujiwara RT,Gazzinelli RT,Bartholomeu DC

更新日期：2013-10-31 00:00:00

abstract：:Adenosine-5'-triphosphate (ATP) is an important phosphate metabolite abundantly found in Mycobacterium leprae bacilli. This pathogen does not derive ATP from its host but has its own mechanism for the generation of ATP. Interestingly, this molecule as well as several antigenic proteins act as bio-markers for the detec...

journal_title：PLoS neglected tropical diseases

authors： Nandi SK,Chakraborty A,Panda AK,Ray SS,Kar RK,Bhunia A,Biswas A

更新日期：2015-03-26 00:00:00