Abstract:
:The consequences of deep wound infections before, during, and after coronary artery bypass grafting have prompted research to clarify risk factors and explore preventive measures to keep infection rates at an irreducible minimum. An analysis of 42 studies in which investigators used multivariate logistic regression analysis revealed that diabetes mellitus and obesity are by far the chief preoperative risk factors. A 4-point preoperative scoring system based on a patient's body mass index and the presence or absence of diabetes is one practical way to determine the risk of mediastinitis, and other risk-estimate methods are being refined. Intraoperative risk factors include prolonged perfusion time, the use of one or more internal mammary arteries as grafts, blood transfusion, and mechanical circulatory assistance. The chief postoperative risk factor is reoperation, usually for bleeding. Unresolved issues include the optimal approach to Staphylococcus aureus nasal colonization and the choice of a prophylactic antibiotic regimen. We recommend that cardiac surgery programs supplement their audit processes and ongoing vigilance for infections with periodic, multidisciplinary reviews of best-practice standards for preoperative, intraoperative, and postoperative patient care.
journal_name
Tex Heart Inst Jjournal_title
Texas Heart Institute journalauthors
Bryan CS,Yarbrough WMsubject
Has Abstractpub_date
2013-01-01 00:00:00pages
125-39issue
2eissn
0730-2347issn
1526-6702journal_volume
40pub_type
杂志文章,评审abstract::Glucose-6-phosphate dehydrogenase (G6PD) protects erythrocytes from oxidative stress and hemolysis; G6PD deficiency is the most prevalent enzymopathy. The United States military routinely performs tests to prevent exposing G6PD-deficient personnel to antimalarial drugs that might cause life-threatening hemolytic react...
journal_title:Texas Heart Institute journal
pub_type: 杂志文章,多中心研究
doi:10.14503/THIJ-16-6052
更新日期:2018-06-01 00:00:00
abstract::We present a case of aortic valve replacement combined with aortic root enlargement, performed on an achondroplastic dwarf with severe calcific aortic stenosis. There are no data about the incidence of valvular diseases in achondroplastic patients. To our knowledge, this is the 1st time that an aortic valve replacemen...
journal_title:Texas Heart Institute journal
pub_type: 杂志文章
doi:
更新日期:2005-01-01 00:00:00
abstract::Our goal was to investigate the efficacy of degradable poly(D,L-lactic-coglycolic acid) (PLGA) scaffolds loaded with basic fibroblast growth factor (bFGF) in inducing cardiac neovascularization, increasing perfusion, and improving cardiac function.For ease of scaffold implantation into the ventricular wall, we develop...
journal_title:Texas Heart Institute journal
pub_type: 杂志文章
doi:
更新日期:2009-01-01 00:00:00
abstract::The development of accelerated coronary artery disease after heart transplantation remains the limiting factor for long-term survival. The most widely accepted hypothesis to explain the development of this vascular lesion is chronic immunologic injury to the vessel wall, which leads to recruitment of monocytes and lym...
journal_title:Texas Heart Institute journal
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract::Orthoclone OKT3 (muromonab-CD3), a murine monoclonal antibody that virtually eliminates circulating T cells and inhibits medullary lymphocyte function, has recently been found effective in reversing stubborn severe allograft rejection after heart transplantation. To determine the influence of OKT3 therapy on the devel...
journal_title:Texas Heart Institute journal
pub_type: 杂志文章
doi:
更新日期:1988-01-01 00:00:00
abstract::The inflammatory response induced by cardiopulmonary bypass decreases vascular tone, which in turn can lead to vasoplegic syndrome. Indeed the hypotension consequent to on-pump cardiac surgery often necessitates vasopressor and intravenous fluid support. Methylene blue counteracts vasoplegic syndrome by inhibiting the...
journal_title:Texas Heart Institute journal
pub_type: 杂志文章
doi:10.14503/THIJ-14-4470
更新日期:2015-10-01 00:00:00
abstract::Fulminant myocarditis is a rare but potentially life-threatening illness caused by 5-fluorouracil cardiotoxicity. Data supporting the use of extracorporeal membrane oxygenation for the treatment of fulminant myocarditis are limited. A 49-year-old, previously healthy white man, recently diagnosed with anal squamous cel...
journal_title:Texas Heart Institute journal
pub_type: 杂志文章
doi:10.14503/THIJ-15-5100
更新日期:2016-04-01 00:00:00
abstract::Celiac artery aneurysms are rare and typically warrant surgical treatment. Atherosclerosis is their chief cause. Symptomatic patients usually present with abdominal pain. Surgical resection of celiac artery aneurysms is associated with low morbidity and mortality rates. We report the case of a patient whose 2.2-cm cel...
journal_title:Texas Heart Institute journal
pub_type: 杂志文章
doi:10.14503/THIJ-16-5802
更新日期:2017-02-01 00:00:00
abstract::Newer generations of assist devices for postcardiotomy support in patients with ventricular failure have eliminated bearings and incorporated suspended impellers, smaller cannulae and hardware, and simplified insertion techniques. We describe the use of a surgically implanted, percutaneous, continuous-flow centrifugal...
journal_title:Texas Heart Institute journal
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract::Pseudoaneurysm of the mitral-aortic intervalvular fibrosa is a rare but serious sequela of endocarditis or valve replacement surgery. Because open-heart surgery is a high-risk treatment option, alternative methods are sought. We present the case of a 77-year-old man with a noninfected mechanical mitral valve whose pse...
journal_title:Texas Heart Institute journal
pub_type: 杂志文章
doi:10.14503/THIJ-14-4156
更新日期:2015-06-01 00:00:00
abstract::Blunt thoracoabdominal trauma is most often caused by high-velocity motor-vehicle accidents or by falls from a height. The clinical spectrum of cardiac injuries arising from this type of trauma varies from myocardial contusion to valvular rupture. Intracardiac valvular rupture is rarely observed, and few cases have be...
journal_title:Texas Heart Institute journal
pub_type: 杂志文章
doi:
更新日期:2009-01-01 00:00:00
abstract::Within a 40-month period ending in June 1992, we used the transseptal approach in performing mitral valve surgery on 18 patients. The patients selected had 1 or more of the following indications: small left atrium; adhesions from previous cardiac surgery or rheumatic activity; large, organized left atrial thrombus: th...
journal_title:Texas Heart Institute journal
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract::Since the adoption of off-pump coronary artery bypass surgery (OPCAB), numerous investigators have compared its short- and long-term results with those of on-pump coronary bypass surgery. Some reports of OPCAB were quite favorable, whereas others were critical, claiming that it resulted in incomplete revascularization...
journal_title:Texas Heart Institute journal
pub_type: 杂志文章
doi:
更新日期:2009-01-01 00:00:00
abstract::Legionella infection can manifest itself in many clinical forms, most commonly as pneumonia, but rarely in the form of myocardial involvement. Legionella with myocardial involvement independent of pneumonia is almost never seen in the adult population and therefore is cited only a handful of times in the medical liter...
journal_title:Texas Heart Institute journal
pub_type: 杂志文章
doi:
更新日期:2009-01-01 00:00:00
abstract::Cardiac amyloidosis is an infiltrative cardiomyopathy with a grave prognosis. Its clinical manifestations include restrictive cardiomyopathy, diastolic heart failure, conduction defects, and arrhythmias. Isolated cardiac involvement and significant conduction disturbances are reported very infrequently. We report a ra...
journal_title:Texas Heart Institute journal
pub_type: 杂志文章
doi:
更新日期:2013-01-01 00:00:00
abstract::The Model 6120 ball valve prosthesis introduced in 1965 is still strongly supported as a mitral valve substitute in many centers around the world. A current reassessment of the performance of this prosthesis is therefore pertinent to current medical practice. In this institution since 1974, 227 Starr-Edwards caged bal...
journal_title:Texas Heart Institute journal
pub_type: 杂志文章
doi:
更新日期:1985-03-01 00:00:00
abstract::We present a case in which endovascular stenting was used for recurrent proximal para-anastomotic stenosis 11 years after aorto-bi-iliac bypass grafting for severe aorto-iliac occlusive disease. A 55-year-old woman presented with worsening bilateral hip and buttock claudication. At presentation, her resting ankle-brac...
journal_title:Texas Heart Institute journal
pub_type: 杂志文章
doi:
更新日期:2002-01-01 00:00:00
abstract::Many patients who undergo cardiac transplantation do so as a result of end-stage dilated cardiomyopathy (DC). Little is known about the causes of this condition, but long-term follow-up studies reveal a high incidence of DC in patients who have had acute viral myocarditis. The following article examines the role of my...
journal_title:Texas Heart Institute journal
pub_type: 杂志文章
doi:
更新日期:1987-09-01 00:00:00
abstract::There is mounting evidence in support of a significant role for influenza infection in the development of atherosclerosis and the triggering of its complications. Here we review the biologic basis of this relationship, with special emphasis on the pro-inflammatory and pro-thrombotic effects of influenza infection. We ...
journal_title:Texas Heart Institute journal
pub_type: 杂志文章,评审
doi:
更新日期:2004-01-01 00:00:00
abstract::We report a case of Carney's complex in a 12-year-old boy who had the characteristic features of multiple cutaneous tumors, pigmentation, and biatrial myxoma. His large right atrial myxoma almost occluded the tricuspid valve and presented a life-threatening emergency. Surgery saved his life, but recurrence of myxoma w...
journal_title:Texas Heart Institute journal
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract::In Part 1 of this review, we discussed how plaque rupture is the most common underlying cause of most cases of unstable angina/non-ST-segment-elevation myocardial infarction (UA/NSTEMI) and how early risk stratification is vital for the timely diagnosis and treatment of acute coronary syndromes (ACS). Now, in Part 2, ...
journal_title:Texas Heart Institute journal
pub_type: 杂志文章,评审
doi:
更新日期:2010-01-01 00:00:00
abstract::Ischemic mitral regurgitation, a complication of myocardial infarction, is associated with a poor prognosis and can result in postinfarction congestive heart failure. The preferred treatment of its chronic form is a matter of debate. Herein, we report the early and midterm results in 44 patients with chronic ischemic ...
journal_title:Texas Heart Institute journal
pub_type: 杂志文章
doi:
更新日期:2009-01-01 00:00:00
abstract::The Bentall procedure is the standard operation for patients who have lesions of the ascending aorta associated with aortic valve disease. In many cases, however, mechanical prosthetic conduits are not suitable. There are few reports in the English-language medical literature concerning the mid- to long-term outcome o...
journal_title:Texas Heart Institute journal
pub_type: 杂志文章
doi:
更新日期:2004-01-01 00:00:00
abstract::We report 4 consecutive cases in which the double-patch technique was used to repair an inferior postinfarction ventricular septal rupture. The ventricular septal perforation was closed directly by stitching, with the same sutures, 2 autologous pericardial patches onto both sides of the affected septum, through only a...
journal_title:Texas Heart Institute journal
pub_type: 杂志文章
doi:
更新日期:2005-01-01 00:00:00
abstract::The glutaraldehyde-preserved stented porcine xenograft valve has been durable in adult patients with a low incidence of valve-related complications. In children, however, early degeneration and calcification of this valve is now being reported. The etiology of the early degeneration is still unclear but may be related...
journal_title:Texas Heart Institute journal
pub_type: 杂志文章
doi:
更新日期:1982-03-01 00:00:00
abstract::We report a case of an 11-year-old girl who presented with a slowly enlarging mass in the right posterolateral chest wall. Computed tomography showed a soft-tissue mass 8.5 × 7.5 × 5.5 cm in size, arising from the right posterolateral 9th, 10th, and 11th intercostal spaces. Magnetic resonance imaging confirmed a vascu...
journal_title:Texas Heart Institute journal
pub_type: 杂志文章
doi:
更新日期:2010-01-01 00:00:00
abstract::The rupture of a mycotic femoral artery pseudoaneurysm in an intravenous drug abuser is a limb- and life-threatening condition that necessitates emergency intervention. Emergency stent-grafting appears to be a viable, minimally invasive alternative, or a bridge, to subsequent open surgery. Caution is required in cases...
journal_title:Texas Heart Institute journal
pub_type: 杂志文章
doi:10.14503/THIJ-13-3882
更新日期:2014-12-01 00:00:00
abstract::Lyme disease is the most prevalent tick-borne disease in the United States. It is caused by the spirochete Borrelia burgdorferi. Cardiac involvement is seen in 4% to 10% of patients with Lyme disease. The principal manifestation of Lyme carditis is self-limited conduction system disease, with predominant involvement o...
journal_title:Texas Heart Institute journal
pub_type: 杂志文章
doi:10.14503/THIJ-14-4126
更新日期:2015-06-01 00:00:00
abstract::In recent years, researchers have investigated the relationship between biological markers of inflammation and prognosis in patients who experience acute coronary syndromes; however, the association between plasma fibrinogen and coronary heart disease is still not clear. We studied the prognostic value of fibrinogen, ...
journal_title:Texas Heart Institute journal
pub_type: 杂志文章
doi:
更新日期:2010-01-01 00:00:00
abstract::Congenital pericardial diverticula and cysts are extremely uncommon lesions within the anterior mediastinum. Both lesions derive from the pericardial celom and represent different stages of a common embryogenesis. Initial reports date from the 19th century. Surgical pioneers were Otto Pickhardt, who removed a pericard...
journal_title:Texas Heart Institute journal
pub_type: 历史文章,杂志文章,评审
doi:
更新日期:2012-01-01 00:00:00