A Reminder of Methylene Blue's Effectiveness in Treating Vasoplegic Syndrome after On-Pump Cardiac Surgery.

Abstract:

:The inflammatory response induced by cardiopulmonary bypass decreases vascular tone, which in turn can lead to vasoplegic syndrome. Indeed the hypotension consequent to on-pump cardiac surgery often necessitates vasopressor and intravenous fluid support. Methylene blue counteracts vasoplegic syndrome by inhibiting the formation of nitric oxide. We report the use of methylene blue in a 75-year-old man who developed vasoplegic syndrome after cardiac surgery. After the administration of methylene blue, his hypotension improved to the extent that he could be weaned from vasopressors. The use of methylene blue should be considered in patients who develop hypotension refractory to standard treatment after cardiac surgery.

journal_name

Tex Heart Inst J

authors

Manghelli J,Brown L,Tadros HB,Munfakh NA

doi

10.14503/THIJ-14-4470

subject

Has Abstract

pub_date

2015-10-01 00:00:00

pages

491-4

issue

5

eissn

0730-2347

issn

1526-6702

journal_volume

42

pub_type

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