Abstract:
BACKGROUND:Epilepsy is the third most common disease affecting the brain in the elderly. Current demographic trends will lead to an increased prevalence of epilepsy in the general population. METHOD:A selective literature search revealed 102 relevant publications as of September 2008, 50 of which were original articles. RESULTS:The level of evidence was found to be very low. No guidelines, systematic reviews or meta-analyses are available, and there have been only three randomized, double-blind trials of treatment for epilepsy in the elderly. The seizures often escape clinical attention, because premonitory symptoms (aura) and secondary generalization into tonic-clonic seizures are both rarer in older patients. On the other hand, sudden loss of consciousness from various causes becomes more common with increasing age, presenting a challenge in differential diagnosis. Treatment is often more complex because of comorbidities and multiple other drugs, and requires a cautious approach. Drug interactions, in particular, require special attention. On the positive side, epileptic seizures in the elderly seem to be more easily controlled by medications than they are in young adults. CONCLUSIONS:Epilepsy is often more difficult to recognize in old age. The treatment is hampered by side effects and drug interactions. Thus, certainty about the diagnosis is indispensable, and the treatment often requires the use of newer-generation antiepileptic drugs.
journal_name
Dtsch Arztebl Intjournal_title
Deutsches Arzteblatt internationalauthors
Werhahn KJdoi
10.3238/arztebl.2009.0135subject
Has Abstractpub_date
2009-02-01 00:00:00pages
135-42issue
9issn
1866-0452journal_volume
106pub_type
杂志文章,评审abstract:BACKGROUND:Cirrhosis of the liver is the end stage of chronic liver disease. Among the many liver disorders that can lead to cirrhosis, some progress rapidly (years) and others more slowly (decades). In Germany, cirrhosis is often a consequence of fatty liver disease due to alcoholism or other causes, but can also be c...
journal_title:Deutsches Arzteblatt international
pub_type: 杂志文章,评审
doi:10.3238/arztebl.2013.0085
更新日期:2013-02-01 00:00:00
abstract:BACKGROUND:Adverse drug events (ADE) are a common cause of hospital admission as well as a common complication of inpatient care. The current reporting systems in Germany are of only limited use for the identification of ADE. The aim of this study is to examine the potential usefulness of ICD-10 coded diagnoses in rout...
journal_title:Deutsches Arzteblatt international
pub_type: 杂志文章
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abstract:BACKGROUND:Delirium is a common complication in elderly hospitalized patients. It prolongs the length of hospital stay, raises costs, increases the workload of the nursing staff, and may necessitate transfer of the patient to a nursing home. The risk of postoperative delirium is particularly high in elderly patients wi...
journal_title:Deutsches Arzteblatt international
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更新日期:2015-04-24 00:00:00
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journal_title:Deutsches Arzteblatt international
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doi:10.3238/artzebl.2008.0207
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journal_title:Deutsches Arzteblatt international
pub_type: 杂志文章
doi:10.3238/arztebl.2014.0003
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journal_title:Deutsches Arzteblatt international
pub_type: 杂志文章,评审
doi:10.3238/arztebl.2014.0301
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abstract:BACKGROUND:Isolated non-compaction cardiomyopathy (NCCM) was first described in 1984. This disorder, a primary genetic cardiomyopathy, is now attracting increased attention. METHOD:The current state of the epidemiology, pathogenesis, pathophysiology, clinical features, diagnosis, treatment, and prognosis of NCCM are d...
journal_title:Deutsches Arzteblatt international
pub_type: 杂志文章,评审
doi:10.3238/arztebl.2010.0206
更新日期:2010-03-01 00:00:00
abstract:BACKGROUND:In Germany, public interest in a vegan diet is steadily growing. There are, however, no current data on the macro- and micronutrient status of vegans. METHODS:In a cross-sectional study entitled "The Risks and Benefits of a Vegan Diet" (RBVD), we investigated the dietary intake, basic laboratory parameters,...
journal_title:Deutsches Arzteblatt international
pub_type: 杂志文章
doi:10.3238/arztebl.2020.0575
更新日期:2020-08-31 00:00:00
abstract:BACKGROUND:The German Standing Committee on Vaccination (STIKO) recommends vaccination against human papillomaviruses (HPV) of the high-risk types 16 and 18. The duration of protection afforded by HPV vaccines has been reported in multiple studies to date but has not been systematically evaluated. METHOD:Systematic li...
journal_title:Deutsches Arzteblatt international
pub_type: 杂志文章,meta分析,评审
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更新日期:2014-09-01 00:00:00
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journal_title:Deutsches Arzteblatt international
pub_type: 杂志文章
doi:10.3238/arztebl.2014.0732
更新日期:2014-10-24 00:00:00
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journal_title:Deutsches Arzteblatt international
pub_type: 杂志文章,多中心研究
doi:10.3238/arztebl.2015.0585
更新日期:2015-08-31 00:00:00
abstract:BACKGROUND:Atrial fibrillation is the most common type of cardiac arrhythmia and is associated with elevated rates of stroke, heart failure, hospital admission, and death. Its prevalence in the overall population is 1.5% to 2%. To convert atrial fibrillation to sinus rhythm, cardioversion is needed. METHODS:This revie...
journal_title:Deutsches Arzteblatt international
pub_type: 杂志文章,评审
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更新日期:2015-12-11 00:00:00
abstract:BACKGROUND:The German Federal Law on Radiation Control contains no special provisions for X-ray studies in children and adolescents, even though exposure to ionizing radiation must be kept especially low in young persons, because their tissues are highly radiosensitive. Children, who have many years left to live, are m...
journal_title:Deutsches Arzteblatt international
pub_type: 杂志文章
doi:10.3238/arztebl.2011.0407
更新日期:2011-06-01 00:00:00
abstract:BACKGROUND:Medication reviews and medication management are being used more and more around the world to improve medication safety. Both of these tools were originally conceived as pharmaceutical care activities and have recently been developed into interdisciplinary approaches. We studied the efficacy of interprofessi...
journal_title:Deutsches Arzteblatt international
pub_type: 杂志文章,随机对照试验
doi:10.3238/arztebl.2016.0741
更新日期:2016-11-04 00:00:00
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pub_type: 杂志文章,实务指引
doi:10.3238/arztebl.2016.0729
更新日期:2016-10-28 00:00:00
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journal_title:Deutsches Arzteblatt international
pub_type: 杂志文章,评审
doi:10.3238/arztebl.2011.0347
更新日期:2011-05-01 00:00:00
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journal_title:Deutsches Arzteblatt international
pub_type: 杂志文章
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abstract:BACKGROUND:Prostatic cancer (PCa) is the most common cancer in men in Germany. The goal of this review is to define the indication for hormonal treatment in patients over age 70. METHODS:A selective search of the literature up to 2008 for the terms "prostate cancer", "androgen suppression and deprivation", "hormone th...
journal_title:Deutsches Arzteblatt international
pub_type: 杂志文章,meta分析,评审
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journal_title:Deutsches Arzteblatt international
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更新日期:2018-11-05 00:00:00
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journal_title:Deutsches Arzteblatt international
pub_type: 杂志文章,评审
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journal_title:Deutsches Arzteblatt international
pub_type: 杂志文章,meta分析,评审
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journal_title:Deutsches Arzteblatt international
pub_type: 杂志文章
doi:10.3238/arztebl.2012.0849
更新日期:2012-12-01 00:00:00
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journal_title:Deutsches Arzteblatt international
pub_type: 杂志文章,评审
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abstract:BACKGROUND:The percentage of organ donors among the German population is very low, and the supply of organs does not meet the demand. Relatively few organ explantations are performed in Germany, compared to other countries. The central element leading up to organ explantation is the donor's consent. This can be express...
journal_title:Deutsches Arzteblatt international
pub_type: 杂志文章
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更新日期:2020-03-13 00:00:00
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journal_title:Deutsches Arzteblatt international
pub_type: 杂志文章,评审
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更新日期:2010-05-01 00:00:00
abstract::[This corrects the article DOI: 10.3238/arztebl.2017.0661.]. ...
journal_title:Deutsches Arzteblatt international
pub_type: 已发布勘误
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更新日期:2017-11-01 00:00:00
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journal_title:Deutsches Arzteblatt international
pub_type: 杂志文章,评审
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更新日期:2011-10-01 00:00:00
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pub_type: 杂志文章
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更新日期:2016-07-01 00:00:00
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pub_type: 杂志文章
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