How can the response to volume expansion in patients with spontaneous respiratory movements be predicted?

abstract：INTRODUCTION:In critically ill patients, delirium is a serious and frequent disorder that is associated with a prolonged intensive care and hospital stay and an increased morbidity and mortality. Without the use of a delirium screening instrument, delirium is often missed by ICU nurses and physicians. The effects of im...

journal_title：Critical care (London, England)

authors： van den Boogaard M,Pickkers P,van der Hoeven H,Roodbol G,van Achterberg T,Schoonhoven L

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:The present study assessed the opinion of general practitioners (GPs) concerning their relationships with intensivists. METHODS:An anonymous questionnaire was mailed to 7,239 GPs. GPs were asked about their professional activities, postgraduate intensive care unit (ICU) training, the rate of patient admit...

journal_title：Critical care (London, England)

authors： Etesse B,Jaber S,Mura T,Leone M,Constantin JM,Michelet P,Zoric L,Capdevila X,Malavielle F,Allaouchiche B,Orban JC,Fabbro-Peray P,Lefrant JY,AzuRéa Group.

更新日期：2010-01-01 00:00:00

abstract：:Diagnosis of sepsis is complicated by non-specific clinical definitions and delays in laboratory analysis using tests which may have very poor predictive values. The use of host biomarker signature sets, which when measured in combination have high predictive values, offers a paradigm shift forwards for rapid, near-pa...

journal_title：Critical care (London, England)

authors： Silman NJ

更新日期：2013-12-04 00:00:00

abstract：INTRODUCTION:Norepinephrine, regularly used to increase systemic arterial blood pressure and thus improve cerebral perfusion following severe traumatic brain injury (TBI), may activate platelets. This, in turn, could promote microthrombosis formation and induce additional brain damage. METHODS:The objective of this st...

journal_title：Critical care (London, England)

authors： Tschuor C,Asmis LM,Lenzlinger PM,Tanner M,Härter L,Keel M,Stocker R,Stover JF

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Chemokine (C-X3-C motif) receptor 1 (CX3CR1) was identified as the most differentially expressed gene between survivors and non-survivors in two independent cohorts of septic shock patients and was proposed as a marker of sepsis-induced immunosuppression. Whether such a biomarker is associated with mortality...

journal_title：Critical care (London, England)

authors： Friggeri A,Cazalis MA,Pachot A,Cour M,Argaud L,Allaouchiche B,Floccard B,Schmitt Z,Martin O,Rimmelé T,Fontaine-Kesteloot O,Page M,Piriou V,Bohé J,Monneret G,Morisset S,Textoris J,Vallin H,Blein S,Maucort-Boulch D,

更新日期：2016-06-30 00:00:00

abstract：:Certain noble gases, though inert, exhibit remarkable biological properties. Notably, xenon and argon provide neuroprotection in animal models of central nervous system injury. In the previous issue of Critical Care, Loetscher and colleagues provided further evidence that argon may have therapeutic properties for neur...

journal_title：Critical care (London, England)

authors： Sanders RD,Ma D,Maze M

更新日期：2010-01-01 00:00:00

abstract：INTRODUCTION:Delayed gastric emptying occurs frequently in critically ill patients and has the potential to adversely affect both the rate, and extent, of nutrient absorption. However, there is limited information about nutrient absorption in the critically ill, and the relationship between gastric emptying (GE) and ab...

journal_title：Critical care (London, England)

authors： Chapman MJ,Fraser RJ,Matthews G,Russo A,Bellon M,Besanko LK,Jones KL,Butler R,Chatterton B,Horowitz M

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Neurocritical illness is a growing healthcare problem with profound socioeconomic effects. We assessed differences in healthcare costs and long-term outcome for different forms of neurocritical illnesses treated in the intensive care unit (ICU). METHODS:We used the prospective Finnish Intensive Care Consort...

journal_title：Critical care (London, England)

authors： Raj R,Bendel S,Reinikainen M,Hoppu S,Laitio R,Ala-Kokko T,Curtze S,Skrifvars MB

更新日期：2018-09-20 00:00:00

abstract：BACKGROUND:The acute respiratory distress syndrome (ARDS) is characterized by disruption of the alveolar-capillary barrier resulting in accumulation of proteinaceous edema and increased inflammatory cells in the alveolar space. We previously found that endothelial progenitor cell (EPC) exosomes prevent endothelial dysf...

journal_title：Critical care (London, England)

authors： Zhou Y,Li P,Goodwin AJ,Cook JA,Halushka PV,Chang E,Zingarelli B,Fan H

更新日期：2019-02-13 00:00:00

abstract：:The rapid response system concept is one of the first patient-centered and organizational-wide systems aimed at preventing deaths and serious adverse events. It has been strongly argued that we need a benchmark that reflects the care of a deteriorating patient across the organization using a 'score to door time'; that...

journal_title：Critical care (London, England)

authors： Hillman KM

更新日期：2011-01-01 00:00:00

abstract：:The pathogenesis of sepsis-induced multiple organ failure may crucially depend on the development of mitochondrial dysfunction and consequent cellular energetic failure. According to this hypothesis, interventions aimed at preventing or reversing mitochondrial damage may have major clinical relevance, although the tim...

journal_title：Critical care (London, England)

authors： Protti A,Singer M

更新日期：2006-01-01 00:00:00

abstract：:Three pulse contour systems for monitoring cardiac output - LiDCO Plus™, PiCCO Plus™ and FloTrac™ - were compared in postcardiac surgery patients. None of the three methods demonstrated good trending ability according to concordance analysis. Pulse contour systems remain unreliable in the haemodynamically unstable pat...

journal_title：Critical care (London, England)

authors： Critchley LA

更新日期：2011-01-19 00:00:00

abstract：INTRODUCTION:Little is known about mortality rates following general surgical procedures in the United Kingdom. Deaths are most common in the 'high-risk' surgical population consisting mainly of older patients, with coexisting medical disease, who undergo major surgery. Only limited data are presently available to desc...

journal_title：Critical care (London, England)

authors： Pearse RM,Harrison DA,James P,Watson D,Hinds C,Rhodes A,Grounds RM,Bennett ED

更新日期：2006-01-01 00:00:00

abstract：:Critical care medicine in China has made great advances in recent decades. This has led to an unavoidable issue: end-of-life ethics. With advances in medical technology and therapeutics allowing the seemingly limitless maintenance of life, the exact time of death of an individual patient is often determined by the dec...

journal_title：Critical care (London, England)

authors： Li LB

更新日期：2013-12-04 00:00:00

abstract：INTRODUCTION:The accurate assessment of intravascular volume status for the therapy of severe hypovolemia and shock is difficult and critical to critically ill patients. Non-invasive evaluation of fluid responsiveness by the rapid infusion of a very limited amount of volume is an important clinical goal. This study aim...

journal_title：Critical care (London, England)

authors： Wu Y,Zhou S,Zhou Z,Liu B

更新日期：2014-05-27 00:00:00

abstract：INTRODUCTION:Bacterial meningitis (BM) is a severe complication in patients with aneurysmal subarachnoid haemorrhage (SAH). Clinical signs of meningitis are often masked by SAH-related symptoms, and routine cerebrospinal fluid (CSF) analysis fails to indicate BM. Microdialysis (MD) is a technique for monitoring cerebra...

journal_title：Critical care (London, England)

authors： Schlenk F,Frieler K,Nagel A,Vajkoczy P,Sarrafzadeh AS

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:Ultrasound of the lung and quantification of B lines was recently introduced as a novel tool to detect overhydration. In the present study, we aimed to evaluate a four-region protocol of lung ultrasound to determine the pulmonary fluid status in ventilated patients in the intensive care unit. METHODS:Fift...

journal_title：Critical care (London, England)

authors： Enghard P,Rademacher S,Nee J,Hasper D,Engert U,Jörres A,Kruse JM

更新日期：2015-02-06 00:00:00

abstract：INTRODUCTION:Prompt diagnosis of candidaemia and invasive candidosis is crucial to the early initiation of antifungal therapy. The poor sensitivity of blood cultures (BCs) has led to the development of fungal glycan tests as a diagnostic adjunct. We analysed the performance of tests for the detection of circulating β-D...

journal_title：Critical care (London, England)

authors： Poissy J,Sendid B,Damiens S,Ichi Ishibashi K,François N,Kauv M,Favory R,Mathieu D,Poulain D

更新日期：2014-06-29 00:00:00

abstract：:In a group of postoperative patients, Taniguchi and coworkers compared the effect of a computerized system for weaning against 'manual care'. The computerized system involved automatic adjustments to the level of pressure support to achieve a target respiratory rate. Manual care involved adjustments to the level of pr...

journal_title：Critical care (London, England)

authors： Adigüzel N,Güngör G,Tobin MJ

更新日期：2009-01-01 00:00:00

abstract：:Controversy exists on the role of hyperoxia in major trauma with brain injury. Hyperoxia on arterial blood gas has been associated with acute lung injury and pulmonary complications, impacting clinical outcome. The hyperoxia could be reflective of the physiological interventions following major systemic trauma. Despit...

journal_title：Critical care (London, England)

authors： Narotam PK

更新日期：2013-10-16 00:00:00

abstract：:Mechanotransduction holds the underlying mechanisms of ventilator-induced lung injury. Research on this subject, however, could be difficult for clinicians, especially when results are controversial. A recent study by Li and co-workers is used as an example, to explain how to critically read literatures related to bas...

journal_title：Critical care (London, England)

authors： Liu M

更新日期：2007-01-01 00:00:00

abstract：:High-mobility group box 1 (HMGB1) is a DNA-binding protein that also exhibits proinflammatory cytokine-like activity. HMGB1 is passively released by necrotic cells and also is actively secreted by immunostimulated macrophages, dendritic cells, and enterocytes. Although circulating HMGB1 levels are increased relative t...

journal_title：Critical care (London, England)

authors： Fink MP

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Sepsis is a major health issue in preterm infants. Biomarkers are used to diagnose and monitor patients with sepsis, but C-reactive protein (CRP) is proven not predictive at onset of late onset neonatal sepsis (LONS) diagnosis. The aim of this study was to evaluate the association of interleukin-6(IL-6), pro...

journal_title：Critical care (London, England)

authors： Kurul Ş,Simons SHP,Ramakers CRB,De Rijke YB,Kornelisse RF,Reiss IKM,Taal HR

更新日期：2021-01-06 00:00:00

abstract：BACKGROUND:In order to improve assessment and outcome prediction in patients suffering from traumatic brain injury (TBI), cerebral protein levels in serum have been suggested as biomarkers of injury. However, despite much investigation, biomarkers have yet to reach broad clinical utility in TBI. This study is a 9-year ...

journal_title：Critical care (London, England)

authors： Thelin EP,Jeppsson E,Frostell A,Svensson M,Mondello S,Bellander BM,Nelson DW

更新日期：2016-09-08 00:00:00

abstract：:During the past 50 years, caring for the critically ill has become increasingly complex and the need for an intensivist has become more evident. Management by intensivists has become a quality indicator for many ICUs. Numerous small studies have demonstrated the beneficial effect of intensivists on outcomes in the cri...

journal_title：Critical care (London, England)

authors： Levy MM

更新日期：2013-10-14 00:00:00

abstract：INTRODUCTION:Data on the incidence of a hypercoagulable state in trauma, as measured by thromboelastometry (ROTEM), is limited and the prognostic value of hypercoagulability after trauma on outcome is unclear. We aimed to determine the incidence of hypercoagulability after trauma, and to assess whether early hypercoagu...

journal_title：Critical care (London, England)

authors： Müller MC,Balvers K,Binnekade JM,Curry N,Stanworth S,Gaarder C,Kolstadbraaten KM,Rourke C,Brohi K,Goslings JC,Juffermans NP

更新日期：2014-12-25 00:00:00

abstract：INTRODUCTION:Acute respiratory distress syndrome (ARDS) has heterogeneous etiologies, rapid progressive change and a high mortality rate. To improve the outcome of ARDS, accurate diagnosis is essential to the application of effective early treatment. The present study investigated the clinical effects and safety of ope...

journal_title：Critical care (London, England)

authors： Kao KC,Tsai YH,Wu YK,Chen NH,Hsieh MJ,Huang SF,Huang CC

更新日期：2006-01-01 00:00:00

abstract：INTRODUCTION:Down-regulation of ex-vivo cytokine production is a specific feature in patients with sepsis. Cytokine downregulation was studied focusing on caspase-1 activation and conversion of pro-interleukin-1β into interleukin-1β (IL-1β). METHODS:Peripheral blood mononuclear cells were isolated from a) 92 patients ...

journal_title：Critical care (London, England)

authors： Giamarellos-Bourboulis EJ,van de Veerdonk FL,Mouktaroudi M,Raftogiannis M,Antonopoulou A,Joosten LA,Pickkers P,Savva A,Georgitsi M,van der Meer JW,Netea MG

更新日期：2011-01-01 00:00:00

abstract：:Outcomes studies of infections with resistant bacteria often do not account appropriately for intermediate variables--events in the causal pathway between the exposure and the outcome--when controlling for confounders. We discuss how failure to distinguish between confounders and intermediate variables can bias the an...

journal_title：Critical care (London, England)

authors： Schwaber MJ,Carmeli Y

更新日期：2006-01-01 00:00:00

abstract：INTRODUCTION:The interdependence between endotoxemia, gram negative (GN) bacteremia and mortality has been extensively studied. Underlying patient risk and GN bacteremia types are possible confounders of the relationship. METHODS:Published studies with ≥ 10 patients in either ICU or non-ICU settings, endotoxemia detec...

journal_title：Critical care (London, England)

authors： Hurley JC,Guidet B,Offenstadt G,Maury E

更新日期：2012-08-07 00:00:00