Enlightening chronic obstructive pulmonary disease through patients' and caregivers' narratives.

abstract：BACKGROUND:Patients with chronic obstructive pulmonary disease (COPD) often have multiple underlying comorbidities, which may lead to increased health care resource utilization (HCRU) and costs. OBJECTIVE:To describe the comorbidity profiles of COPD patients and examine the associations between the presence of comorbi...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Schwab P,Dhamane AD,Hopson SD,Moretz C,Annavarapu S,Burslem K,Renda A,Kaila S

更新日期：2017-02-23 00:00:00

abstract：INTRODUCTION:Effects of pulmonary rehabilitation (PR) in chronic obstructive pulmonary disease (COPD) patients with severely impaired health status are poorly documented since these patients are usually excluded from clinical trials. This retrospective, observational study aims to study the impact of disease on health ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： van Ranst D,Otten H,Meijer JW,van 't Hul AJ

更新日期：2011-01-01 00:00:00

abstract：:Background: The Global Initiative for Chronic Obstructive Lung Disease (GOLD) released an updated document in 2017 that excluded the spirometric parameter in the classification of patients. The validity of this new classification system in predicting mortality and respiratory hospitalization is still uncertain. Method...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Lee SJ,Yun SS,Ju S,You JW,Cho YJ,Jeong YY,Kim JY,Kim HC,Lee JD

更新日期：2019-04-29 00:00:00

abstract：Background:Endoscopic lung volume reduction (eLVR) is a therapeutic option for selected patients with COPD and severe emphysema. Infectious exacerbations are serious events in these vulnerable patients; hence, prophylactic antibiotics are often prescribed postinterventionally. However, data on the microbiological airwa...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Trudzinski FC,Seiler F,Wilkens H,Metz C,Kamp A,Bals R,Gärtner B,Lepper PM,Becker SL

更新日期：2017-12-19 00:00:00

abstract：OBJECTIVE:To determine the feasibility and efficacy of a six-month, cell phone-based exercise persistence intervention for patients with chronic obstructive pulmonary disease (COPD) following pulmonary rehabilitation. METHODS:Participants who completed a two-week run-in were randomly assigned to either MOBILE-Coached ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Nguyen HQ,Gill DP,Wolpin S,Steele BG,Benditt JO

更新日期：2009-01-01 00:00:00

abstract：:COPD exerts a substantial burden on health and health care systems globally and will continue to do so for the foreseeable future. Treatment however can be costly and health care providers are interested in both whether treatments can offer improvements in disease burden and whether they represent value for money. Eco...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Starkie HJ,Briggs AH,Chambers MG

更新日期：2008-01-01 00:00:00

abstract：Background:COPD is characterized by a persistent inflammatory response, especially against cigarette smoke. COPD patients may develop varying degrees of emphysematous destruction of the lungs. A pathophysiological role for miRNAs in COPD has been suggested in several studies. We examined changes in microRNAs expression...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Cazorla-Rivero S,Mura-Escorche G,Gonzalvo-Hernández F,Mayato D,Córdoba-Lanús E,Casanova C

更新日期：2020-10-29 00:00:00

abstract：STUDY OBJECTIVES:Patients with chronic obstructive pulmonary disease (COPD) have low exercise capacity and low content of high energetic phosphates in their skeletal muscles. The aim of the present study was to investigate whether creatine supplementation together with exercise training may increase physical performanc...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Faager G,Söderlund K,Sköld CM,Rundgren S,Tollbäck A,Jakobsson P

更新日期：2006-01-01 00:00:00

abstract：Rationale:Individual socioeconomic status has been shown to influence the outcomes of patients with chronic obstructive pulmonary disease (COPD). However, contextual factors may also play a role. The objective of this study is to evaluate the association between neighborhood socioeconomic disadvantage measured by the a...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Galiatsatos P,Woo H,Paulin LM,Kind A,Putcha N,Gassett AJ,Cooper CB,Dransfield MT,Parekh TM,Oates GR,Barr RG,Comellas AP,Han MK,Peters SP,Krishnan JA,Labaki WW,McCormack MC,Kaufman JD,Hansel NN

更新日期：2020-05-05 00:00:00

abstract：Background:Frailty can inform management approaches for individuals with COPD. However, inpatient measures of frailty are seldom employed because they are time-consuming or inapplicable for bed-bound patients. We investigated the feasibility and potential of an innovative sensor-based upper-extremity function (UEF) tes...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Ehsani H,Mohler MJ,Golden T,Toosizadeh N

更新日期：2018-12-18 00:00:00

abstract：BACKGROUND:Long-acting inhaled bronchodilators, including anticholinergic tiotropium, are recommended for the maintenance therapy of chronic obstructive pulmonary disease (COPD). It has been shown in a number of studies that treatment with tiotropium alleviates symptoms, improves exercise tolerance, health status, and ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Jahnz-Różyk K,Szepiel P

更新日期：2015-03-18 00:00:00

abstract：BACKGROUND:The chronic obstructive pulmonary disease (COPD) assessment test (CAT) is a short questionnaire that has facilitated health status measurements in subjects with COPD. However, it remains controversial as to whether the CAT can be used as a suitable substitute for the St George's Respiratory Questionnaire (SG...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Morishita-Katsu M,Nishimura K,Taniguchi H,Kimura T,Kondoh Y,Kataoka K,Ogawa T,Watanabe F,Arizono S,Nishiyama O,Nakayasu K,Imaizumi K,Hasegawa Y

更新日期：2016-07-07 00:00:00

abstract：INTRODUCTION:COPD exacerbation negatively impacts the patient's quality of life and lung function, increases mortality, and increases socioeconomic costs. In a real-world setting, the majority of patients with COPD have mild-to-moderate airflow limitation. Therefore, it is important to evaluate COPD exacerbation in pat...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Kim JK,Lee SH,Lee BH,Lee CY,Kim do J,Min KH,Kim SK,Yoo KH,Jung KS,Hwang YI

更新日期：2016-06-16 00:00:00

abstract：:The course of COPD is punctuated by acute exacerbations that are associated with an increase in the morbidity and mortality related to this chronic disease and may contribute to its rate of progression. Therefore, preventing and treating exacerbations are major goals of COPD management. The role of tiotropium in the p...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Tashkin DP

更新日期：2010-02-18 00:00:00

abstract：BACKGROUND:The purpose of this study was to describe the prevalence of renal and hepatic disease, related laboratory abnormalities, and potentially hepatotoxic and nephrotoxic medication use in a population-based cohort of persons with chronic obstructive pulmonary disease (COPD). METHODS:This was a retrospective case...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Mapel DW,Marton JP

更新日期：2013-01-01 00:00:00

abstract：Purpose:Previous studies have described the incidence, risk factors, and outcomes for patients with acute exacerbations of COPD (AECOPD) developing acute kidney injury (AKI). However, little is known about the differences between community-acquired AKI (CA-AKI) and hospital-acquired AKI (HA-AKI) in patients with AECOPD...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Cao CC,Chen DW,Li J,Ma MQ,Chen YB,Cao YZ,Hua X,Shao W,Wan X

更新日期：2018-07-17 00:00:00

abstract：BACKGROUND:Smoking is a major risk factor for chronic obstructive pulmonary disease (COPD); however, the similarities and differences in clinical presentation between smokers and nonsmokers are not fully described in patients with COPD. This study was designed to address this issue in a general teaching hospital in the...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Zhang J,Lin XF,Bai CX

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:indacaterol is a novel, inhaled once-daily ultra-long-acting β(2)-agonist for the treatment of chronic obstructive pulmonary disease (COPD). OBJECTIVES:this study compared the onset of action of single doses of indacaterol 150 and 300 μg with salbutamol 200 μg, salmeterol-fluticasone 50/500 μg, and placebo ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Balint B,Watz H,Amos C,Owen R,Higgins M,Kramer B,INSURE Study Investigators.

更新日期：2010-09-07 00:00:00

abstract：Aim:The aim of the current study was to assess the serum levels of trace minerals/heavy metals in COPD patients with and without pulmonary hypertension (PH) and to investigate their correlations to demographic, clinical, and biochemical variables. Materials and methods:This cross-sectional study was performed in Van Y...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Asker S,Asker M,Yeltekin AC,Aslan M,Ozbay B,Demir H,Turan H

更新日期：2018-05-31 00:00:00

abstract：Background:Previous studies have suggested that β2-adrenergic receptor (ADRB2) is associated with COPD. However, the role of genetic polymorphisms in ADRB2 on COPD has not been evaluated yet. Methods:In this study, SNaPshot genotyping, luciferase assay, chromatin immunoprecipitation and real-time polymerase chain reac...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Li JX,Fu WP,Zhang J,Zhang XH,Sun C,Dai LM,Zhong L,Yu L,Zhang YP

更新日期：2018-03-16 00:00:00

abstract：Background:Few studies have examined changes in the pain experience of patients with COPD and predictors of pain in these patients. Objectives:The objectives of the study were to examine whether distinct groups of COPD patients could be identified based on changes in the occurrence and severity of pain over 12 months ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Bentsen SB,Miaskowski C,Cooper BA,Christensen VL,Henriksen AH,Holm AM,Rustøen T

更新日期：2018-03-06 00:00:00

abstract：BACKGROUND:Concerns have been raised that treatment of COPD with inhaled corticosteroids may increase pneumonia risk. Responding to a request from the European Medicines Agency Pharmacovigilance Risk Assessment Committee, a pooled analysis of interventional studies compared pneumonia risk with inhaled budesonide-contai...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Hollis S,Jorup C,Lythgoe D,Martensson G,Regnell P,Eckerwall G

更新日期：2017-04-05 00:00:00

abstract：:The landmark study of Fletcher and Peto on the natural history of tobacco smoke-related chronic airflow obstruction suggested that decline in the forced expiratory volume in the first second (FEV(1)) in chronic obstructive pulmonary disease (COPD) is slow at the beginning, becoming faster with more advanced disease. T...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Tantucci C,Modina D

更新日期：2012-01-01 00:00:00

abstract：Background:The use of inhaled corticosteroid (ICS) in patients with chronic obstructive pulmonary disease (COPD) decreases the frequency of COPD exacerbations. Recently, pneumonia was reported as a complication of ICS in patients with COPD. However, there have been few reports concerning the relationship between ICS an...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Hirano R,Fujita M,Matsumoto T,On R,Watanabe K

更新日期：2018-10-23 00:00:00

abstract：Purpose:Acute exacerbation of COPD (AECOPD) is among the most frequent causes for hospital admission, causing morbidity and mortality. Infection is the most frequent cause, and studies on pollution have shown higher hospital admission and mortality with inconsistent results. The objective was to identify if there is a ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Morantes-Caballero JA,Fajardo Rodriguez HA

更新日期：2019-07-11 00:00:00

abstract：INTRODUCTION:Noninvasive ventilation (NIV) improves survival among patients with hypercapnic respiratory failure in hospital, but evidence for its use in domiciliary settings is limited. A patient's underlying risk of having an exacerbation may affect any potential benefit that can be gained from domiciliary NIV. This ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Dretzke J,Moore D,Dave C,Mukherjee R,Price MJ,Bayliss S,Wu X,Jordan RE,Turner AM

更新日期：2016-09-16 00:00:00

abstract：BACKGROUND:The aim of this study was to determine whether long-term intermittent azithromycin therapy reduces the frequency of exacerbation in severe chronic obstructive pulmonary disease (COPD). METHODS:We retrospectively investigated the clinical benefits of long-term azithromycin (500 mg orally three times per week...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Pomares X,Montón C,Espasa M,Casabon J,Monsó E,Gallego M

更新日期：2011-01-01 00:00:00

abstract：:Bronchiectasis is defined by permanent and abnormal widening of the bronchi. This process occurs in the context of chronic airway infection and inflammation. It is usually diagnosed using computed tomography scanning to visualize the larger bronchi. Bronchiectasis is also characterized by mild to moderate airflow obst...

journal_title：International journal of chronic obstructive pulmonary disease

authors： King PT

更新日期：2009-01-01 00:00:00

abstract：Objective:To determine the clinical and economic consequences of inhaled corticosteroid doses and particle size in patients on triple-inhalation therapy for COPD. Methods:Patients aged ≥40 years who initiated treatment with multi-inhaler triple-inhaled therapy between 1 January 2015 and 31 March were included and foll...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Sicras-Mainar A,de Abajo FJ,Izquierdo-Alonso JL

更新日期：2020-12-09 00:00:00

abstract：Introduction:Understanding the breadth of patients' support needs is important for the delivery of person-centered care, particularly in progressive long-term conditions such as chronic obstructive pulmonary disease (COPD). Existing reviews identify important aspects of managing life with COPD with which patients may n...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Gardener AC,Ewing G,Kuhn I,Farquhar M

更新日期：2018-03-26 00:00:00