Gap between real-world data and clinical research within hospitals in China: a qualitative study.

abstract：OBJECTIVES:To establish the prevalence of self-reported vision impairment (VI) in Southwest Cameroon and describe associated care-seeking practices, functional limitations and economic hardships. DESIGN:A three-stage clustered sampling household community-based survey. SETTING:The Southwest region of Cameroon. PARTI...

journal_title：BMJ open

authors： Mbeboh SN,Christie SA,Carvalho M,Dickson D,Nana T,Embolo F,Dicker R,Juillard C,Chichom Mefire A

更新日期：2020-11-26 00:00:00

abstract：OBJECTIVE:To assess the impact of chronic kidney disease (CKD) and cardiovascular comorbidity on mortality in a multiethnic primary care population. DESIGN:Retrospective cohort study. SETTING:Inner-city primary care trust in West Midlands, UK. PARTICIPANTS:Individuals aged 40 years and older, of South Asian, black o...

journal_title：BMJ open

authors： Jesky M,Lambert A,Burden AC,Cockwell P

更新日期：2013-12-03 00:00:00

abstract：OBJECTIVES:The prevalence of neck/back pain (NBP) is high worldwide. Limited number of studies have investigated workers with occasional NBP regarding the risk of developing long-duration activity limiting NBP (LNBP). The objectives were to assess (1) the effect of poor work ability and sleep disturbances in persons wi...

journal_title：BMJ open

authors： Holm LW,Bohman T,Lekander M,Magnusson C,Skillgate E

更新日期：2020-06-03 00:00:00

abstract：OBJECTIVES:To investigate factors associated with movement behaviours among White British (WB) and South Asian (SA) children aged 6-8 years during school terms and holidays. DESIGN:Cross-sectional. SETTING:Three primary schools from the Bradford area, UK. PARTICIPANTS:One hundred and sixty WB and SA children aged 6-...

journal_title：BMJ open

authors： Nagy LC,Faisal M,Horne M,Collings P,Barber S,Mohammed M

更新日期：2019-08-18 00:00:00

abstract：OBJECTIVES:Injection drug use is the most important risk factor for the spread of HIV in China over the past two decades. People who use drugs (PWUD) who were diagnosed at an early stage with HIV have gradually developed AIDS. This study investigated the factors associated with disease progression following HIV diagnos...

journal_title：BMJ open

authors： Luo H,Sun M,Du J

更新日期：2019-07-03 00:00:00

abstract：INTRODUCTION:Psoriasis vulgaris often leads to a significant impaired quality of life and dissatisfaction with the existing therapeutic approaches. However, patients' quality of life and treatment satisfaction are of utmost importance, since it is positively related to therapy adherence and encourages patient's complia...

journal_title：BMJ open

authors： Fink C,Schank TE,Trenkler N,Uhlmann L,Schäkel K

更新日期：2017-06-30 00:00:00

abstract：OBJECTIVE:The study aims to identify the mediating factors of the relationship between education achievement and incident type 2 diabetes mellitus (T2DM) in older adults. DESIGN:Population-based cohort study. SETTING:Participants were recruited from the German federal state of Saarland. PARTICIPANTS:Participants wer...

journal_title：BMJ open

authors： Steele CJ,Schöttker B,Marshall AH,Kouvonen A,O'Doherty MG,Mons U,Saum KU,Boffetta P,Trichopoulou A,Brenner H,Kee F

更新日期：2017-04-17 00:00:00

abstract：OBJECTIVES:To identify patterns in euthanasia requests and practices relating to psychiatric patients; to generate recommendations for future research. DESIGN:Retrospective analysis of data obtained through medical file review. SETTING:Outpatient psychiatric clinical setting in the Dutch-speaking region of Belgium, b...

journal_title：BMJ open

authors： Thienpont L,Verhofstadt M,Van Loon T,Distelmans W,Audenaert K,De Deyn PP

更新日期：2015-07-27 00:00:00

abstract：INTRODUCTION:Physical activity (PA) has diverse benefits for physical and mental health and can reduce symptoms of mental illness. Adults with mental illness face practical, psychosocial and socioeconomic barriers to adopting and maintaining PA, and it is unclear how to effectively promote PA in this group. Supervised ...

journal_title：BMJ open

authors： Chapman JJ,Suetani S,Siskind D,Kisely S,Breakspear M,Byrne JH,Patterson S

更新日期：2018-09-08 00:00:00

abstract：INTRODUCTION:Chronic inguinal pain is a frequently occurring problem in athletes. A diagnosis of inguinal disruption is performed by exclusion of other conditions causing groin pain. Up to now, conservative medical management is considered to be the primary treatment for this condition. Relevant large and prospective c...

journal_title：BMJ open

authors： Voorbrood CE,Goedhart E,Verleisdonk EJ,Sanders F,Naafs D,Burgmans JP

更新日期：2016-01-06 00:00:00

abstract：OBJECTIVES:The aim of this study was to develop a single blood test that could determine gestational age and estimate the risk of preterm birth by measuring serum metabolites. We hypothesised that serial metabolic modelling of serum analytes throughout pregnancy could be used to describe fetal gestational age and proje...

journal_title：BMJ open

authors： Sylvester KG,Hao S,You J,Zheng L,Tian L,Yao X,Mo L,Ladella S,Wong RJ,Shaw GM,Stevenson DK,Cohen HJ,Whitin JC,McElhinney DB,Ling XB

更新日期：2020-12-02 00:00:00

abstract：OBJECTIVE:To investigate the incidence of primary care presentations for herpes zoster (zoster) in a representative New Zealand population and to evaluate the utilisation of primary healthcare services following zoster diagnosis. DESIGN:A cross-sectional retrospective cohort study used a natural language processing so...

journal_title：BMJ open

authors： Turner NM,MacRae J,Nowlan ML,McBain L,Stubbe MH,Dowell A

更新日期：2018-05-31 00:00:00

abstract：CONTEXT AND OBJECTIVE:Standards for clinical practice guidelines require explicit statements regarding how values and preferences influence recommendations. However, no cancer screening guideline has addressed the key question of what magnitude of benefit people require to undergo screening, given its harms and burdens...

journal_title：BMJ open

authors： Helsingen LM,Zeng L,Siemieniuk RA,Lytvyn L,Vandvik PO,Agoritsas T,Bretthauer M,Guyatt G

更新日期：2020-12-02 00:00:00

abstract：OBJECTIVES:Current clinical guidelines discourage long-term prescription of benzodiazepines and Z-drugs (BZD); however, the practice continues to exist. The aim of this study was to investigate the proportion of long-term BZD prescriptions and its risk factors. DESIGN:Retrospective cohort study using a health insuranc...

journal_title：BMJ open

authors： Takano A,Ono S,Yamana H,Matsui H,Matsumoto T,Yasunaga H,Kawakami N

更新日期：2019-07-26 00:00:00

abstract：OBJECTIVE:To classify wear and non-wear time of accelerometer data for accurately quantifying physical activity in public health or population level research. DESIGN:A bi-moving-window-based approach was used to combine acceleration and skin temperature data to identify wear and non-wear time events in triaxial accele...

journal_title：BMJ open

authors： Zhou SM,Hill RA,Morgan K,Stratton G,Gravenor MB,Bijlsma G,Brophy S

更新日期：2015-05-11 00:00:00

abstract：INTRODUCTION:In western countries, early visiting services (EVS) have been proposed as a recent intervention to reduce both general practitioner workload and hospital admissions among housebound individuals experiencing a healthcare need within the community. EVS involves the delegation of the patient home visits to ot...

journal_title：BMJ open

authors： Abrams R,Wong G,Mahtani KR,Tierney S,Boylan AM,Roberts N,Park S

更新日期：2018-11-13 00:00:00

abstract：INTRODUCTION:Mortality and morbidity following surgery are pressing public health concerns in the USA. Traditional prediction models for postoperative adverse outcomes demonstrate good discrimination at the population level, but the ability to forecast an individual patient's trajectory in real time remains poor. We pr...

journal_title：BMJ open

authors： Fritz BA,Chen Y,Murray-Torres TM,Gregory S,Ben Abdallah A,Kronzer A,McKinnon SL,Budelier T,Helsten DL,Wildes TS,Sharma A,Avidan MS

更新日期：2018-04-10 00:00:00

abstract：INTRODUCTION:Home-based self-rehabilitation programmes combined with botulinum toxin injections (BTIs) appear to be a relevant approach to increase the recommended intensive rehabilitation of patients with spasticity following a stroke. The literature highlights a lack of evidence of beneficial effects of this adjuvant...

journal_title：BMJ open

authors： Bonnyaud C,Gallien P,Decavel P,Marque P,Aymard C,Pellas F,Isner ME,Boyer FC,Muller F,Daviet JC,Dehail P,Perrouin-Verbe B,Bayle N,Coudeyre E,Perennou D,Laffont I,Ropers J,Domingo-Saidji NY,Bensmail D,Roche N,ADJU-T

更新日期：2018-08-30 00:00:00

abstract：INTRODUCTION:International prevalence rates for problem gambling are estimated at 2.3%. Problem gambling is a serious global public health concern due to adverse personal and social consequences. Previous research evaluating the effectiveness of psychological interventions for the treatment of problem gambling has been...

journal_title：BMJ open

authors： Thomas SA,Merkouris SS,Browning CJ,Radermacher H,Feldman S,Enticott J,Jackson AC

更新日期：2015-11-24 00:00:00

abstract：INTRODUCTION:Smoking remains the leading cause of preventable death in the USA but can be reduced through policy interventions. Computational models of smoking can provide estimates of the projected impact of tobacco control policies and can be used to inform public health decision making. We outline a protocol for sim...

journal_title：BMJ open

authors： Tam J,Levy DT,Jeon J,Clarke J,Gilkeson S,Hall T,Feuer EJ,Holford TR,Meza R

更新日期：2018-03-23 00:00:00

abstract：OBJECTIVE:This study aimed to characterise rheumatic manifestations and autoantibodies in 432 patients diagnosed with infective endocarditis (IE) in Shanghai. DESIGN, SETTING AND PARTICIPANTS:A retrospective study was conducted in Ruijin Hospital from 1997 to 2017. The clinical and laboratory characteristics of a tota...

journal_title：BMJ open

authors： Zhou Z,Ye J,Teng J,Liu H,Cheng X,Sun Y,Su Y,Chi H,Wang F,Yang C,Jin W

更新日期：2020-02-12 00:00:00

abstract：OBJECTIVES:To evaluate the implementation of a new procedure for screening and treatment of malnutrition for older people in community settings and to identify factors promoting or inhibiting its implementation as a routine aspect of care. DESIGN:Prospective process evaluation using mixed methods with pre/post-impleme...

journal_title：BMJ open

authors： Bracher M,Steward K,Wallis K,May CR,Aburrow A,Murphy J

更新日期：2019-08-10 00:00:00

abstract：INTRODUCTION:Substantial resources are required to provide lifelong postoperative care to people with cochlear implants. Most patients visit the clinic annually. We introduced a person-centred remote follow-up pathway, giving patients telemedicine tools to use at home so they would only visit the centre when interventi...

journal_title：BMJ open

authors： Cullington H,Kitterick P,Weal M,Margol-Gromada M

更新日期：2018-04-20 00:00:00

abstract：OBJECTIVE:Mild traumatic brain injury (mTBI) has been insufficiently researched, and its definition remains elusive. Investigators are confronted by heterogeneity in patients, mechanism of injury and outcomes. Findings are thus often limited in generalisability and clinical application. Serum protein biomarkers are inc...

journal_title：BMJ open

authors： Mercier E,Tardif PA,Emond M,Ouellet MC,de Guise É,Mitra B,Cameron P,Le Sage N

更新日期：2017-09-27 00:00:00

abstract：OBJECTIVE:To examine the associations between consumption of sweetened products, daytime sleepiness (DS) and psychological distress (PD) in a Catholic Middle-Eastern Canadian community, and to test the hypothesis that the association between DS and consumption of sweetened products is mediated by PD. DESIGN:A cross-se...

journal_title：BMJ open

authors： Moubarac JC,Cargo M,Receveur O,Daniel M

更新日期：2013-02-13 00:00:00

abstract：OBJECTIVE:Recent data on sustained hypertension and obesity among school-going children and adolescents in India are limited. This study evaluates the prevalence of sustained hypertension and obesity and their risk factors among urban and rural adolescents in northern India. SETTING:A school-based, cross-sectional sur...

journal_title：BMJ open

authors： Mohan B,Verma A,Singh K,Singh K,Sharma S,Bansal R,Tandon R,Goyal A,Singh B,Chhabra ST,Aslam N,Wander GS,Roy A,Prabhakaran D

更新日期：2019-09-08 00:00:00

abstract：OBJECTIVES:Two oral targeted therapies, gefitinib and erlotinib, were first approved and then launched into the market for treatment of late-stage non-small cell lung cancer (NSCLC) in Taiwan in 2003 and 2006, respectively. The aim of this study were to determine the trends in lung cancer burden and examine changes in ...

journal_title：BMJ open

authors： Hsu JC,Wei CF,Yang SC,Lin PC,Lee YC,Lu CY

更新日期：2020-05-10 00:00:00

abstract：PURPOSE:Depression is the most common psychiatric disorder and the largest contributor to global disability. The Australian Genetics of Depression study was established to recruit a large cohort of individuals who have been diagnosed with depression at some point in their lifetime. The purpose of establishing this coho...

journal_title：BMJ open

authors： Byrne EM,Kirk KM,Medland SE,McGrath JJ,Colodro-Conde L,Parker R,Cross S,Sullivan L,Statham DJ,Levinson DF,Licinio J,Wray NR,Hickie IB,Martin NG

更新日期：2020-05-26 00:00:00

abstract：INTRODUCTION:Individuals with Parkinson's disease (PD) have to deal with several aspects of voice and speech decline and thus alteration of communication ability during the course of the disease. Among these communication impairments, 3 major challenges include: (1) dysarthria, consisting of orofacial motor dysfunction...

journal_title：BMJ open

authors： Pinto S,Cardoso R,Sadat J,Guimarães I,Mercier C,Santos H,Atkinson-Clement C,Carvalho J,Welby P,Oliveira P,D'Imperio M,Frota S,Letanneux A,Vigario M,Cruz M,Martins IP,Viallet F,Ferreira JJ

更新日期：2016-11-17 00:00:00

abstract：INTRODUCTION:Physical activity, healthy eating and maintaining a healthy weight are associated with reduced risk of cardiovascular disease, type 2 diabetes and cancer and with improved mental health. Despite these benefits, many men do not meet recommended physical activity guidelines and have poor eating behaviours. M...

journal_title：BMJ open

authors： Caperchione CM,Bottorff JL,Oliffe JL,Johnson ST,Hunt K,Sharp P,Fitzpatrick KM,Price R,Goldenberg SL

更新日期：2017-09-06 00:00:00