Abstract:
:We found that a single nucleotide polymorphism (SNP) in the nucleoprotein gene of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from a patient interfered with detection in a widely used commercial assay. Some 0.2% of the isolates in the EpiCoV database contain this SNP. Although SARS-CoV-2 was still detected by the other probe in the assay, this underlines the necessity of targeting two independent essential regions of a pathogen for reliable detection.
journal_name
Euro Surveilljournal_title
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletinauthors
Ziegler K,Steininger P,Ziegler R,Steinmann J,Korn K,Ensser Adoi
10.2807/1560-7917.ES.2020.25.39.2001650subject
Has Abstractpub_date
2020-10-01 00:00:00issue
39eissn
1025-496Xissn
1560-7917journal_volume
25pub_type
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