Guiding outbreak management by the use of influenza A(H7Nx) virus sequence analysis.

Abstract:

:The recently identified human infections with avian influenza A(H7N9) viruses in China raise important questions regarding possible source and risk to humans. Sequence comparison with an influenza A(H7N7) outbreak in the Netherlands in 2003 and an A(H7N1) epidemic in Italy in 1999–2000 suggests that widespread circulation of A(H7N9) viruses must have occurred in China. The emergence of human adaptation marker PB2 E627K in human A(H7N9) cases parallels that of the fatal A(H7N7) human case in the Netherlands.

journal_name

Euro Surveill

authors

Jonges M,Meijer A,Fouchier RA,Koch G,Li J,Pan JC,Chen H,Shu YL,Koopmans MP

subject

Has Abstract

pub_date

2013-04-18 00:00:00

pages

20460

issue

16

eissn

1025-496X

issn

1560-7917

journal_volume

18

pub_type

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