Association among cytokine profiles of innate and adaptive immune responses and clinical-virological features in untreated patients with chronic hepatitis B.

abstract：BACKGROUND:Tuberculosis (TB) is a major global health problem and remains the leading cause of morbidity and mortality in developing countries. Routinely used TB diagnostic methods, in most endemic areas, are time-consuming, often less-sensitive, expensive and inaccessible to most patients. Therefore, there is an urgen...

journal_title：BMC infectious diseases

authors： Bentaleb EM,Abid M,El Messaoudi MD,Lakssir B,Ressami EM,Amzazi S,Sefrioui H,Ait Benhassou H

更新日期：2016-09-27 00:00:00

abstract：BACKGROUND:ProvLab Alberta provides all laboratory testing for Bordetella pertussis including sporadic cases and outbreak investigations through collaborations with provincial public health partners. We describe B. pertussis activity in Alberta from July 2004 to December 2012. METHODS:Laboratory testing for pertussis ...

journal_title：BMC infectious diseases

authors： Fathima S,Ferrato C,Lee BE,Simmonds K,Yan L,Mukhi SN,Li V,Chui L,Drews SJ

更新日期：2014-01-30 00:00:00

abstract：BACKGROUND:Increasing the dosage of daptomycin may be advantageous in severe infection by enhancing bactericidal activity and pharmacodynamics. However, clinical data on using daptomycin at doses above 6 mg/kg in Asian population are limited. METHODS:A retrospective observational cohort study of all hospitalized adult...

journal_title：BMC infectious diseases

authors： Lai CC,Sheng WH,Wang JT,Cheng A,Chuang YC,Chen YC,Chang SC

更新日期：2013-02-04 00:00:00

abstract：BACKGROUND:Pulmonary nocardiosis frequently occurs in immunocompromised hosts and in some immunocompetent hosts with chronic lung disease; however, few reports have described pulmonary nocardiosis with nontuberculous mycobacterial lung infection. Here we report for the first time two cases of pulmonary nocardiosis caus...

journal_title：BMC infectious diseases

authors： Yagi K,Ishii M,Namkoong H,Asami T,Fujiwara H,Nishimura T,Saito F,Kimizuka Y,Asakura T,Suzuki S,Kamo T,Tasaka S,Gonoi T,Kamei K,Betsuyaku T,Hasegawa N

更新日期：2014-12-10 00:00:00

abstract：BACKGROUND:Benefits using the 13-valent pneumococcal conjugate vaccine (PCV13) in adults are controversial. This study investigated clinical effectiveness of PCV13 vaccination in preventing hospitalisation from pneumonia among middle-aged and older adults. METHODS:Population-based cohort study involving 2,025,730 indi...

journal_title：BMC infectious diseases

authors： Vila-Corcoles A,Ochoa-Gondar O,de Diego C,Satue E,Aragón M,Vila-Rovira A,Gomez-Bertomeu F,Magarolas R,Figuerola-Massana E,Raga X,Perez MO,Ballester F

更新日期：2018-04-27 00:00:00

abstract：BACKGROUND:Viral central nervous system (CNS) infections are common in countries where malaria is endemic but, due to limited laboratory facilities, few studies have systematically examined the prevalence and clinical consequences of the presence of viruses in cerebrospinal fluid (CSF) from children with suspected CNS ...

journal_title：BMC infectious diseases

authors： Laman M,Hwaiwhanje I,Bona C,Warrel J,Aipit S,Smith D,Noronha J,Siba P,Mueller I,Betuela I,Davis TM,Manning L

更新日期：2014-11-26 00:00:00

abstract：BACKGROUND:During the fifth wave of human H7N9 infections, a novel highly pathogenic (HP) H7N9 variant emerged with an insertion of multiple basic amino acids in the HA cleavage site. Moreover, a neuraminidase inhibitor (NAI) resistance (R292K in NA) mutation was found in H7N9 isolates from humans, poultry and the envi...

journal_title：BMC infectious diseases

authors： Yang Y,Li S,Wong G,Ma S,Xu Z,Zhao X,Li H,Xu W,Zheng H,Lin J,Zhao Q,Liu W,Liu Y,Gao GF,Bi Y

更新日期：2018-08-15 00:00:00

abstract：BACKGROUND:Blood stream infections (BSI) are life-threatening infections in intensive care units (ICU), and prognosis is highly dependent on early detection. Procalcitonin levels have been shown to accurately and quickly distinguish between BSI and noninfectious inflammatory states in critically ill patients. It is, ho...

journal_title：BMC infectious diseases

authors： Charles PE,Ladoire S,Snauwaert A,Prin S,Aho S,Pechinot A,Olsson NO,Blettery B,Doise JM,Quenot JP

更新日期：2008-12-02 00:00:00

abstract：BACKGROUND:Refugees in sub-Saharan Africa face both the risk of HIV infection and barriers to HIV testing. We conducted a pilot study to determine the feasibility and acceptability of home-based HIV testing in Nakivale Refugee Settlement in Uganda and to compare home-based and clinic-based testing participants in Nakiv...

journal_title：BMC infectious diseases

authors： O'Laughlin KN,He W,Greenwald KE,Kasozi J,Chang Y,Mulogo E,Faustin ZM,Njogu P,Walensky RP,Bassett IV

更新日期：2018-07-16 00:00:00

abstract：BACKGROUND:Australia is developing a chlamydia screening program. This study aimed to determine the attitudes of young women to the introduction of chlamydia screening in Australian General Practice. METHODS:In-depth face-to-face interviews with 24 young women from across Victoria, Australia, attending a randomly sele...

journal_title：BMC infectious diseases

authors： Pavlin NL,Parker R,Fairley CK,Gunn JM,Hocking J

更新日期：2008-05-09 00:00:00

abstract：BACKGROUND:Helicobacter cinaedi is rarely identified as a cause of infected aneurysms; however, the number of reported cases has been increasing over several decades, especially in Japan. We report three cases of aortic aneurysm infected by H. cinaedi that were successfully treated using meropenem plus surgical stent g...

journal_title：BMC infectious diseases

authors： Matsuo T,Mori N,Mizuno A,Sakurai A,Kawai F,Starkey J,Ohkushi D,Abe K,Yamasaki M,Ito J,Yoshino K,Mikami Y,Uehara Y,Furukawa K

更新日期：2020-11-17 00:00:00

abstract：BACKGROUND:The study of the endotoxin tolerance phenomenon in light of the recently defined roles of mast cells and toll-like receptors as essential components of the innate immune response and as orchestrators of acquired immunity may reveal potentially useful mechanisms of immunomodulation of infectious and allergic ...

journal_title：BMC infectious diseases

authors： Saturnino SF,Prado RO,Cunha-Melo JR,Andrade MV

更新日期：2010-08-14 00:00:00

abstract：BACKGROUND:Syndromic management of STIs has been advocated as simplified and cheap approach. Youth have been reported to be at increased risk of acquiring STIs which can facilitate HIV transmission. We have investigated the relationship between the syndromic management and specific aetiology diagnosis and its relations...

journal_title：BMC infectious diseases

authors： Chalamilla G,Mbwana J,Mhalu F,Mmari E,Majigo M,Swai A,Urassa W,Sandstrom E

更新日期：2006-02-10 00:00:00

abstract：BACKGROUND:Rubella infection in pregnant women can result in serious effects, such as miscarriages, stillbirths, and congenital rubella syndrome (CRS). However, very little is known about the rubella seroprevalence among pregnant women in China. METHODS:This is a cross-sectional and hospital-based study. From June 201...

journal_title：BMC infectious diseases

authors： Meng Q,Luo J,Li L,Shi W,Yu J,Shen Y,Li L,Wang Y,Yao K

更新日期：2018-03-15 00:00:00

abstract：BACKGROUND:Diarrhea is the second most common cause of death among children less than 5 years of age worldwide. The etiological agents of diarrhea in the southeast coastal area of China were studied from July 2009 to December 2014. METHODS:A total of the 2318 patients were enrolled in this study and examined for the p...

journal_title：BMC infectious diseases

authors： Zheng S,Yu F,Chen X,Cui D,Cheng Y,Xie G,Yang X,Han D,Wang Y,Zhang W,Chen Y

更新日期：2016-08-20 00:00:00

abstract：BACKGROUND:This retrospective study evaluated the performance of a lipoarabinomannan (LAM)-based immunological method for diagnosing pleural tuberculosis (TB) from pleural effusion samples. Results were compared to those obtained using conventional culture and molecular testing methods. METHODS:Suspected pleural TB pa...

journal_title：BMC infectious diseases

authors： Liang Q,Pang Y,Yang Y,Li H,Guo C,Yang X,Chen X

更新日期：2019-06-21 00:00:00

abstract：BACKGROUND:Models of infectious disease are increasingly utilising empirical contact data to quantify the number of potentially infectious contacts between age groups. While a growing body of data is being collected on contact patterns across many populations, less attention has been paid to the social contacts of youn...

journal_title：BMC infectious diseases

authors： Campbell PT,McVernon J,Shrestha N,Nathan PM,Geard N

更新日期：2017-09-20 00:00:00

abstract：BACKGROUND:Estimation of pre-immunisation prevalence of HPV and distribution of HPV types is fundamental to understanding the subsequent impact of HPV vaccination. We describe the type specific prevalence of HPV in females aged 20-21 in Scotland who attended or defaulted from cervical screening using three specimen typ...

journal_title：BMC infectious diseases

authors： Kavanagh K,Sinka K,Cuschieri K,Love J,Potts A,Pollock KG,Cubie H,Donaghy M,Robertson C

更新日期：2013-11-05 00:00:00

abstract：BACKGROUND:HIV-related stigma always is major obstacles to an effective HIV response worldwide. The effect of HIV-related stigma on HIV prevention and treatment is particularly serious in China. This study was to examine stigma attitude towards people living with HIV/AIDS (PLWHA) among general individuals in Heilongjia...

journal_title：BMC infectious diseases

authors： Li X,Yuan L,Li X,Shi J,Jiang L,Zhang C,Yang X,Zhang Y,Zhao D,Zhao Y

更新日期：2017-02-17 00:00:00

abstract：BACKGROUND:While cultivation of pathogens represents a foundational diagnostic approach in the study of infectious diseases, its value for the confirmation of clinical diagnosis of Buruli ulcer is limited by the fact that colonies of Mycobacterium ulcerans appear only after about eight weeks of incubation at 30°C. Howe...

journal_title：BMC infectious diseases

authors： Bratschi MW,Bolz M,Grize L,Kerber S,Minyem JC,Um Boock A,Yeboah-Manu D,Ruf MT,Pluschke G

更新日期：2014-11-30 00:00:00

abstract：BACKGROUND:High-risk strains of human papillomavirus (HPV) cause cervical cancer. American Indian (AI) women in the Northern Plains of the U.S. have significantly higher incidence and mortality rates for cervical cancer than White women in the same geographical area. We compared HPV prevalence, patterns of HPV types, a...

journal_title：BMC infectious diseases

authors： Schmidt-Grimminger DC,Bell MC,Muller CJ,Maher DM,Chauhan SC,Buchwald DS

更新日期：2011-09-24 00:00:00

abstract：BACKGROUND:Low density Plasmodium falciparum infections, below the microscopic detection limit, may play an important role in maintaining malaria transmission in low endemic areas as well as contribute to the maintenance of acquired immunity. Little is known about factors influencing the occurrence of sub-microscopic p...

journal_title：BMC infectious diseases

authors： Shekalaghe S,Alifrangis M,Mwanziva C,Enevold A,Mwakalinga S,Mkali H,Kavishe R,Manjurano A,Sauerwein R,Drakeley C,Bousema T

更新日期：2009-05-21 00:00:00

abstract：BACKGROUNDS:Several studies have evaluated the impact of matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry (MS) combined with antimicrobial stewardship in patients with positive blood cultures; clinical outcomes improved. However, in many hospitals, antimicrobial stewardship is no...

journal_title：BMC infectious diseases

authors： Jeon YD,Seong H,Kim D,Ahn MY,Jung IY,Jeong SJ,Choi JY,Song YG,Yong D,Lee K,Kim JM,Ku NS

更新日期：2018-08-09 00:00:00

abstract：BACKGROUND:Risk of pneumocystosis after discontinuation of primary or secondary prophylaxis among HIV-infected patients before CD4 counts increase to >==200 cells/microL (early discontinuation) after receiving highly active antiretroviral therapy (HAART) is rarely investigated. METHODS:Medical records of 660 HIV-infec...

journal_title：BMC infectious diseases

authors： Cheng CY,Chen MY,Hsieh SM,Sheng WH,Sun HY,Lo YC,Liu WC,Hung CC

更新日期：2010-05-21 00:00:00

abstract：BACKGROUND:Collecting adequate information on key epidemiological indicators is a prerequisite to informing a public health response to reduce the impact of hepatitis C virus (HCV) infection in Malaysia. Our goal was to overcome the acute data shortage typical of low/middle income countries using statistical modelling ...

journal_title：BMC infectious diseases

authors： McDonald SA,Mohamed R,Dahlui M,Naning H,Kamarulzaman A

更新日期：2014-11-07 00:00:00

abstract：:The ongoing transmission of Mycobacterium (M.) leprae reflected in a very slow decline in leprosy incidence, forces us to be innovative and conduct cutting-edge research. Single dose rifampicin (SDR) as post-exposure prophylaxis (PEP) for contacts of leprosy patients, reduces their risk to develop leprosy by 60%. This...

journal_title：BMC infectious diseases

authors： Mieras LF,Taal AT,van Brakel WH,Cambau E,Saunderson PR,Smith WCS,Prakoeswa CRS,Astari L,Scollard DM,do Nascimento DC,Grosset J,Kar HK,Izumi S,Gillini L,Virmond MCL,Sturkenboom MGG

更新日期：2018-10-05 00:00:00

abstract：BACKGROUND:Staphylococcus aureus strains are now regarded as zoonotic agents. In pastoral settings where human-animal interaction is intimate, multi-drug resistant microorganisms have become an emerging zoonotic issue of public health concern. The study of S. aureus prevalence, antimicrobial resistance and clonal linea...

journal_title：BMC infectious diseases

authors： Asiimwe BB,Baldan R,Trovato A,Cirillo DM

更新日期：2017-06-13 00:00:00

abstract：BACKGROUND:There is an established correlation between maternal education and reduction in childhood mortality. One proposed link is that an increase in maternal education will lead to an increase in health care access and vaccine uptake. Vaccinations are a central preventative child health tool, therefore demonstratin...

journal_title：BMC infectious diseases

authors： Forshaw J,Gerver SM,Gill M,Cooper E,Manikam L,Ward H

更新日期：2017-12-28 00:00:00

abstract：BACKGROUND:On 18 August 2015, Kyegegwa District reported eight deaths during a measles outbreak to the Uganda Ministry of Health (MoH). We investigated this death cluster to verify the cause, identify risk factors, and inform public health interventions. METHODS:We defined a probable measles case as onset of fever and...

journal_title：BMC infectious diseases

authors： Mafigiri R,Nsubuga F,Ario AR

更新日期：2017-07-03 00:00:00

abstract：BACKGROUND:Patients with HIV/AIDS on Antiretroviral Therapy (ART) suffer from physical, psychological and spiritual problems. Despite international policy explicitly stating that a multidimensional approach such as palliative care should be delivered throughout the disease trajectory and alongside treatment, the effect...

journal_title：BMC infectious diseases

authors： Lowther K,Simms V,Selman L,Sherr L,Gwyther L,Kariuki H,Ahmed A,Ali Z,Jenkins R,Higginson IJ,Harding R

更新日期：2012-11-06 00:00:00