Abstract:
INTRODUCTION:The appropriateness of using routinely collected laboratory data combined with administrative data for estimating influenza vaccine effectiveness (VE) is still being explored. This paper outlines a protocol to estimate influenza VE using linked laboratory and administrative data which could act as a companion to estimates derived from other methods. METHODS AND ANALYSIS:We will use the test-negative design to estimate VE for each influenza type/subtype and season. Province-wide individual-level records of positive and negative influenza tests at the Provincial Laboratory for Public Health in Alberta will be linked, by unique personal health numbers, to administrative databases and vaccination records held at the Ministry of Health in Alberta to determine covariates and influenza vaccination status, respectively. Covariates of interests include age, sex, immunocompromising chronic conditions and healthcare setting. Cases will be defined based on an individual's first positive influenza test during the season, and potential controls will be defined based on an individual's first negative influenza test during the season. One control for each case will be randomly selected based on the week the specimen was collected. We will estimate VE using multivariable logistic regression. ETHICS AND DISSEMINATION:Ethics approval was obtained from the University of Alberta's Health Research Ethics Board-Health Panel under study ID Pro00075997. Results will be disseminated by public health officials in Alberta.
journal_name
BMJ Openjournal_title
BMJ openauthors
Scott AN,Buchan SA,Kwong JC,Drews SJ,Simmonds KA,Svenson LWdoi
10.1136/bmjopen-2019-029708subject
Has Abstractpub_date
2019-09-30 00:00:00pages
e029708issue
9issn
2044-6055pii
bmjopen-2019-029708journal_volume
9pub_type
杂志文章相关文献
BMJ Open文献大全abstract:PURPOSE:Patients receiving extracorporeal membrane oxygenation (ECMO) generally receive proton pump inhibitors (PPIs) or histamine-2 receptor antagonists (H2RAs) to avoid major gastrointestinal bleeding. Our aim was to compare outcomes between patients receiving PPIs and H2RAs for stress ulcer prophylaxis during ECMO. ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2020-037534
更新日期:2020-09-29 00:00:00
abstract:OBJECTIVE:This study aimed to evaluate the factor structure of the Chinese version of the 22-item Zarit Burden Interview (ZBI) among family caregivers of patients with schizophrenia in China. METHODS:Using one-stage cluster-sampling design, 324 primary caregivers of patients with schizophrenia in Ningxiang County, Hun...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2016-015621
更新日期:2017-09-29 00:00:00
abstract:OBJECTIVE:To determine ethnic differences in the progression of chronic kidney disease (CKD) and risk of end-stage renal failure (ESRF) and death in adults with type 2 diabetes mellitus (T2DM), and to identify predictors of rapid renal decline. DESIGN:Observational community-based cohort study undertaken from 2006 to ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2017-020145
更新日期:2018-03-27 00:00:00
abstract:OBJECTIVE:To assess differences in weight status and movement behaviour guideline compliance among children aged 5-12 years with and without a family history of non-communicable diseases (NCDs). DESIGN:Prospective. SETTING AND PARTICIPANTS:Women born between 1973 and 1978 were recruited to the Australian Longitudinal...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2020-038789
更新日期:2020-11-03 00:00:00
abstract:INTRODUCTION:Rotator cuff injuries account for up to 70% of pain in the shoulder. However, there remains no consensus on the best surgical treatment for patients with rotator cuff injuries, in terms of the cost-effectiveness and cost-utility of open and arthroscopic methods for rotator cuff repair. The objective of thi...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2020-043126
更新日期:2020-12-28 00:00:00
abstract:INTRODUCTION:Internal temporomandibular joint (TMJ) disorders are present in approximately 80% of patients with symptomatic temporomandibular disorders. Among the minimally invasive therapies, we find the intra-articular infiltration of substances, such as corticosteroids, hyaluronic acid or platelet-rich plasma accomp...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-034327
更新日期:2020-09-06 00:00:00
abstract:INTRODUCTION:Trabeculotomy and combined trabeculotomy-trabeculectomy (CTT) are major surgical options for primary congenital glaucoma (PCG). However, it is unclear which of these two surgical procedures should be recommended as the optimum first-line treatment for PCG. This trial aims to determine whether the outcomes ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-032957
更新日期:2020-02-25 00:00:00
abstract:OBJECTIVES:This review aims to understand what elements of psychosocial interventions are associated with improved outcomes for people with dementia to inform implementation in care homes. DESIGN:A systematic review of qualitative and quantitative intervention studies was undertaken. ELIGIBILITY CRITERIA FOR INCLUDED...
journal_title:BMJ open
pub_type: 杂志文章,评审
doi:10.1136/bmjopen-2016-014177
更新日期:2017-02-09 00:00:00
abstract:OBJECTIVE:Treatment gradients by socioeconomic status have been observed within cancer care in several countries. The objective of this study was to explore whether patients' educational level and social network influence oncologists' clinical decision-making. DESIGN:Semi-structured interviews on factors considered wh...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2012-001248
更新日期:2012-08-24 00:00:00
abstract:INTRODUCTION:Return to work (RTW) after breast cancer (BC) is still a new field of research. The factors determining shorter sick leave duration of patients with BC have not been clearly identified. The aim of this study was to describe work during BC treatment and to identify factors associated with sick leave duratio...
journal_title:BMJ open
pub_type: 杂志文章,多中心研究
doi:10.1136/bmjopen-2017-020276
更新日期:2018-05-18 00:00:00
abstract:OBJECTIVES:To investigate the impact of first eye and second eye cataract surgery on the level of physical activity undertaken by older adults with bilateral cataract. DESIGN:Prospective cohort study. SETTING:Three public ophthalmology clinics in Western Australia. PARTICIPANTS:Fifty-five older adults with bilateral...
journal_title:BMJ open
pub_type: 杂志文章,多中心研究
doi:10.1136/bmjopen-2018-024491
更新日期:2019-03-20 00:00:00
abstract:OBJECTIVE:Nearly 100 000 primary total knee replacements (TKR) are performed in the UK annually. The primary aim of TKR is pain relief, but 10%-34% of patients report chronic pain. The aim of this systematic review was to evaluate the effectiveness of presurgical interventions in preventing chronic pain after TKR. DES...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-033248
更新日期:2020-01-20 00:00:00
abstract:OBJECTIVE:Despite the increasing numbers of published trials of quality improvement (QI) interventions in diabetes, little is known about the risk of bias in this literature. DESIGN:Secondary analysis of a systematic review. DATA SOURCES:Medline, the Cochrane Effective Practice and Organisation of Care (EPOC) databas...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2013-002727
更新日期:2013-04-09 00:00:00
abstract:INTRODUCTION:Antimicrobial resistance has been described as a global crisis-more prudent prescribing is part of the solution. Behaviour change interventions are needed to improve prescribing practice. Presently, the literature documents that context impacts on prescribing decisions, yet insufficient evidence exists to ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2015-009059
更新日期:2015-10-22 00:00:00
abstract:OBJECTIVES:Few studies have investigated the prevalence of adverse drug reactions (ADRs) leading to hospitalisation in Japan. The aim of this study was to determine the prevalence of ADRs leading to hospitalisation and to evaluate the preventability of these ADRs in Japan. DESIGN:A single-centre cross-sectional study ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-030515
更新日期:2019-08-05 00:00:00
abstract:INTRODUCTION:Improving healthcare for all is one of the global health priorities, particularly in disease burdened settings such as sub-Saharan Africa (SSA). Considering the high penetration rate of mobile phones in SSA, mobile health (mHealth) could be used to achieve universal health coverage. The proposed study will...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-036641
更新日期:2020-10-20 00:00:00
abstract:BACKGROUND:Achilles tendon injuries give rise to substantial long-lasting morbidity and pose considerable challenges for clinicians and patients during the lengthy healing period. Current treatment strategies struggle to curb the burden of this injury on health systems and society due to lengthy rehabilitation, work ab...
journal_title:BMJ open
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1136/bmjopen-2017-018135
更新日期:2017-11-16 00:00:00
abstract:OBJECTIVE:To explore how patients who are wait-listed for or who have received a kidney transplant understand the current UK kidney allocation system, and their views on ways to allocate kidneys in the future. DESIGN:Qualitative study using semistructured interviews and thematic analysis based on a pragmatic approach....
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2016-013896
更新日期:2017-01-27 00:00:00
abstract:OBJECTIVES:The number of women entering medicine has increased significantly, yet women are still under-represented at senior levels in academic medicine. To support the gender equality action plan at one School of Medicine, this study sought to (1) identify the range of viewpoints held by staff on how to address gende...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2017-015973
更新日期:2017-08-22 00:00:00
abstract:OBJECTIVE:To examine the association between obese-years and the risk of cardiovascular disease (CVD). STUDY DESIGN:Prospective cohort study. SETTING:Boston, USA. PARTICIPANTS:5036 participants of the Framingham Heart Study were examined. METHODS:Obese-years was calculated by multiplying for each participant the nu...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2014-005629
更新日期:2014-09-17 00:00:00
abstract:OBJECTIVES:Sierra Leone has one of the highest maternal mortality ratios in the world. Timely and well-coordinated referrals are necessary to reduce delays in providing adequate care for women with obstetric complications. This study describes factors affecting timely and adequate referral of women with obstetric compl...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2020-041746
更新日期:2020-12-10 00:00:00
abstract:INTRODUCTION:People are living longer; however, they are not necessarily experiencing good health and well-being as they age. Many older adults live with multiple chronic conditions (MCC), and complex health issues, which adversely affect their day-to-day functioning and overall quality of life. As a result, they frequ...
journal_title:BMJ open
pub_type: 杂志文章,评审
doi:10.1136/bmjopen-2017-018247
更新日期:2017-12-28 00:00:00
abstract:OBJECTIVES:(1) To establish the likelihood of dying within 12 months for a cohort of hospital inpatients in New Zealand (NZ) on a fixed census date; (2) to identify associations between likelihood of death and key sociodemographic, diagnostic and service-related factors and (3) to compare results with, and extend findi...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2017-016880
更新日期:2017-12-06 00:00:00
abstract:OBJECTIVES:University academic achievement may be inversely related to the performance of the secondary (high) school an entrant attended. Indeed, some medical schools already offer 'grade discounts' to applicants from less well-performing schools. However, evidence to guide such policies is lacking. In this study, we ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2017-020291
更新日期:2018-05-23 00:00:00
abstract:PURPOSE:Despite the growing evidence that physical activity and familial factors play a role in low back pain (LBP), there is a lack of robust longitudinal studies that (1) investigate the types and dosages of physical activity that are protective or harmful for LBP, (2) employ objective measures of physical activity a...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-036301
更新日期:2020-07-28 00:00:00
abstract:INTRODUCTION:Prescription-drug use in the USA has increased by more than 60% in the last three decades. Prevalence of prescription-drug use among pregnant women is currently estimated around 50%. Prevalence of illicit drug use in the USA is 14.6% among pregnant adolescents, 8.6% among pregnant young adults and 3.2% amo...
journal_title:BMJ open
pub_type: 杂志文章,多中心研究
doi:10.1136/bmjopen-2017-020248
更新日期:2018-02-17 00:00:00
abstract:INTRODUCTION:Whether acupuncture is efficacious for patients with functional dyspepsia is still controversial. So we designed a randomised controlled trial to settle the problem. METHODS AND ANALYSIS:We designed a multicentre, two-arm, sham-controlled clinical trial. 200 participants with functional dyspepsia will be ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2013-003377
更新日期:2013-07-30 00:00:00
abstract:INTRODUCTION:Australian Aboriginal children are more likely than non-Aboriginal children to have developmental vulnerability at school entry that tracks through to poorer literacy and numeracy outcomes and multiple social and health disadvantages in later life. Empirical evidence identifying the key drivers of positive...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2015-007898
更新日期:2015-05-18 00:00:00
abstract:OBJECTIVE:To review a sample of cluster randomised controlled trials and explore the quality of reporting of (1) enabling or support activities provided to the staff during the trial, (2) strategies used to monitor fidelity throughout the trial and (3) the extent to which the intervention being tested was delivered as ...
journal_title:BMJ open
pub_type: 杂志文章,评审
doi:10.1136/bmjopen-2015-008251
更新日期:2015-10-09 00:00:00
abstract:INTRODUCTION:Limb fractures in children are common yet there are few trials that compare treatments for these injuries. There is significant heterogeneity in the outcomes reported in the paediatric orthopaedic literature, which limits the ability to compare study results and draw firm conclusions. The aim of the CORE-K...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-036224
更新日期:2020-02-28 00:00:00