当前位置： SCI文献检索 > BMJ Open期刊下所有文献 > Determinants of return at work of breast cancer patients: results from the OPTISOINS01 French prospective study.

Determinants of return at work of breast cancer patients: results from the OPTISOINS01 French prospective study.

Abstract：

INTRODUCTION:Return to work (RTW) after breast cancer (BC) is still a new field of research. The factors determining shorter sick leave duration of patients with BC have not been clearly identified. The aim of this study was to describe work during BC treatment and to identify factors associated with sick leave duration. MATERIALS AND METHODS:An observational, prospective, multicentre study was conducted among women with operable BC. A logbook was given to all working patients to record sociodemographic and work-related data over a 1-year period. RESULTS:Work-related data after BC were available for 178 patients (60%). The median age at diagnosis was 50 years (27-77), 87.9% of patients had an invasive form of BC and 25.3% a lymph node involvement. 25.9% had a radical surgery and 24.2% had an axillary dissection. Radiotherapy was performed in 90.9% of patients and chemotherapy in 48.1%. Sick leave was prescribed for 165 patients (92.7%) for a median of 155 days. On univariate analysis, invasive BC (p=0.025), lymph node involvement (p=0.005), radical surgery (p=0.025), axillary dissection (p=0.004), chemotherapy (p<0.001), personal income <€1900/month (p=0.03) and not having received the patient information booklet on RTW (p=0.047) were found to be associated with a longer duration of sick leave. On multivariate analysis, chemotherapy was found to be associated with longer sick leave (OR: 3.5; 95% CI 1.6 to 7.9; p=0.002). The cost of sick leave to French National Health Insurance was fourfold higher in the case of chemotherapy (p<0.001). CONCLUSION:Advanced disease and chemotherapy are major factors that influence sick leave duration during the management of BC. TRIAL REGISTRATION NUMBER:NCT02813317.

journal_name

BMJ Open

journal_title

BMJ open

authors

Arfi A,Baffert S,Soilly AL,Huchon C,Reyal F,Asselain B,Neffati S,Rouzier R,Héquet D

doi

10.1136/bmjopen-2017-020276

subject

Has Abstract

pub_date

2018-05-18 00:00:00

pages

e020276

issue

5

issn

2044-6055

pii

bmjopen-2017-020276

journal_volume

8

pub_type

杂志文章,多中心研究

相关文献

BMJ Open文献大全