Trends in serum creatinine testing in Oxfordshire, UK, 1993-2013: a population-based cohort study.

abstract：OBJECTIVE:The human leucocyte antigen-DO (HLA-DO) gene located in the HLA non-classical class-II region may play a role in treatment response to hepatitis C virus (HCV). This study was conducted to explore the role of single nucleotide polymorphisms (SNPs) in HLA-DO in responding to HCV therapy. SETTING:All patients w...

journal_title：BMJ open

authors： Yao Y,Liu M,Zang F,Yue M,Xia X,Feng Y,Fan H,Zhang Y,Huang P,Yu R

更新日期：2018-04-12 00:00:00

abstract：OBJECTIVES:To assess non-health literature, identify key strategies in promoting more networked teams and groups, apply external ideas to healthcare, and build a model based on these strategies. DESIGN:A systematic review of the literature outside of healthcare. METHOD:Searches guided by Preferred Reporting Items for...

journal_title：BMJ open

authors： Braithwaite J

更新日期：2015-09-24 00:00:00

abstract：OBJECTIVES:The study aimed to understand through qualitative research what patients considered material in their decision to consent to an acute surgical intervention. PARTICIPANTS, SETTING AND INTERVENTION:The patients selected aged between 18 and 90, having been admitted to a major trauma centre to undergo an acute ...

journal_title：BMJ open

authors： Howard A,Webster J,Quinton N,Giannoudis PV

更新日期：2020-10-08 00:00:00

abstract：OBJECTIVES:For people with end-stage renal disease requiring haemodialysis, exercise can improve aspects of quality of life (QoL). However, the relative benefits and risks of different types of exercise in this population are unknown. Therefore, this pilot study aimed to evaluate the feasibility of a main study evaluat...

journal_title：BMJ open

authors： Thompson S,Klarenbach S,Molzahn A,Lloyd A,Gabrys I,Haykowsky M,Tonelli M

更新日期：2016-09-06 00:00:00

abstract：OBJECTIVE:To identify the combination of factors most protective of developmental delay at age 2 among children exposed to poor maternal mental health. DESIGN:Observational cohort study. SETTING:Pregnant women were recruited from primary healthcare offices, the public health laboratory service and community posters i...

journal_title：BMJ open

authors： McDonald SW,Kehler HL,Tough SC

更新日期：2016-11-10 00:00:00

abstract：OBJECTIVES:To assess changes in depressive symptoms and health-related quality of life (HRQOL) after screening for cognitive impairment in people with type 2 diabetes. DESIGN:A prospective cohort study, part of the Cognitive Impairment in Diabetes (Cog-ID) study. SETTING:Participants were screened for cognitive impai...

journal_title：BMJ open

authors： Janssen J,Koekkoek PS,Biessels GJ,Kappelle JL,Rutten GEHM,Cog-ID study group.

更新日期：2019-01-17 00:00:00

abstract：OBJECTIVES:To identify the top 10 unanswered research questions for primary care patient safety research. DESIGN:A modified nominal group technique. SETTING:UK. PARTICIPANTS:Anyone with experience of primary care including: patients, carers and healthcare professionals. 341 patients and 86 healthcare professionals s...

journal_title：BMJ open

authors： Morris RL,Stocks SJ,Alam R,Taylor S,Rolfe C,Glover SW,Whitcombe J,Campbell SM

更新日期：2018-02-28 00:00:00

abstract：INTRODUCTION:Hypercholesterolaemia is estimated to cause 2.6 million deaths annually and one-third of the cases of ischaemic heart disease. In Argentina, the prevalence of hypercholesterolaemia increased between 2005 and 2013 from 27.9% to 29.8%. Only one out of four subjects with a self-reported diagnosis of coronary ...

journal_title：BMJ open

authors： Gulayin P,Irazola V,Lozada A,Chaparro M,Santero M,Gutierrez L,Poggio R,Beratarrechea A,Rubinstein A

更新日期：2017-01-31 00:00:00

abstract：INTRODUCTION:Severe and persistent mental illness (SPMI) can significantly impact a person's social, personal and professional life. Previous studies have demonstrated pharmacists' roles in mental healthcare; however, limited studies to date have focused on pharmacists' roles in providing healthcare services, specifica...

journal_title：BMJ open

authors： El-Den S,McMillan SS,Wheeler AJ,Ng R,Roennfeldt H,O'Reilly CL

更新日期：2020-07-13 00:00:00

abstract：INTRODUCTION:Bicycling is promoted as a transportation and population health strategy globally. Yet bicycling has low uptake in North America (1%-2% of trips) compared with European bicycling cities (15%-40% of trips) and shows marked sex and age trends. Safety concerns due to collisions with motor vehicles are primary...

journal_title：BMJ open

authors： Winters M,Branion-Calles M,Therrien S,Fuller D,Gauvin L,Whitehurst DGT,Nelson T

更新日期：2018-01-21 00:00:00

abstract：OBJECTIVES:Few studies have focused on pulmonary arterial hypertension (PAH) associated with connective tissue diseases (CTDs). The optimal treatment for CTD-PAH has yet to be established. DESIGN:Meta-analysis of the data from evaluations of treatment for PAH generally (19 studies) and CTD-PAH specifically (nine studi...

journal_title：BMJ open

authors： Kuwana M,Watanabe H,Matsuoka N,Sugiyama N

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVE:Danish medical registries are widely used for cardiovascular research, but little is known about the data quality of cardiac interventions. We computed positive predictive values (PPVs) of codes for cardiac examinations, procedures and surgeries registered in the Danish National Patient Registry during 2010-2...

journal_title：BMJ open

authors： Adelborg K,Sundbøll J,Munch T,Frøslev T,Sørensen HT,Bøtker HE,Schmidt M

更新日期：2016-12-09 00:00:00

abstract：INTRODUCTION:Regular toothbrushing with fluoride toothpaste is a fundamental intervention for caries prevention. Professional fluoride application (PFA) is widely considered a beneficial supplement to the routine use of fluoride toothpaste. However, some recent studies have failed to demonstrate the preventive effect o...

journal_title：BMJ open

authors： Yu L,Yu X,Li Y,Li J,Hua F,Song G

更新日期：2020-09-21 00:00:00

abstract：OBJECTIVE:To assess the inclusion of patients as international research partners in Outcome Measures in Rheumatology (OMERACT) conferences and how this has influenced the scope and conduct of outcomes research in rheumatology. DESIGN:A thematic content analysis of OMERACT internal documents, publications and conferenc...

journal_title：BMJ open

authors： de Wit M,Abma T,Koelewijn-van Loon M,Collins S,Kirwan J

更新日期：2013-05-09 00:00:00

abstract：OBJECTIVES:This study examined National Health Insurance claims data to investigate the epidemiology of shoulder disorders in Korea. Detailed information on medical services and related costs was assessed by major shoulder disorder category. DESIGN AND SETTING:The 2014 National Patient Sample dataset provided by the H...

journal_title：BMJ open

authors： Joo H,Lee YJ,Shin JS,Lee J,Kim MR,Koh W,Park Y,Song YK,Cho JH,Ha IH

更新日期：2017-07-12 00:00:00

abstract：OBJECTIVES:To identify the reasons why some people do not participate in bowel cancer screening so that steps can be taken to improve informed decision-making. DESIGN:Qualitative study, using focus groups with thematic analysis of data to identify, analyse and report patterns. Transcripts were repeatedly read and indu...

journal_title：BMJ open

authors： Bradley DT,Treanor C,McMullan C,Owen T,Graham A,Anderson D

更新日期：2015-09-09 00:00:00

abstract：INTRODUCTION:Sarcoidosis is an incurable, chronic granulomatous disease primarily involving the lungs and lymph nodes of unknown aetiology, treated with non-specific anti-inflammatory/immunosuppressive drugs. Persistently symptomatic patients worsen with a disabling, potentially fatal clinical course. To determine a po...

journal_title：BMJ open

authors： Robinson LA,Smith P,Sengupta DJ,Prentice JL,Sandin RL

更新日期：2013-12-23 00:00:00

abstract：OBJECTIVE:In this study, we assess the performance of public hospitals in Saudi Arabia. We detect the sources of inefficiency and estimate the optimal levels of the resources that provide the current level of health services. We enrich our analysis by employing locations and capacities of the hospitals. DESIGN:We empl...

journal_title：BMJ open

authors： Alatawi AD,Niessen LW,Khan JAM

更新日期：2020-01-12 00:00:00

abstract：BACKGROUND:First responders (police, fire and ambulance officers) are at a significantly increased risk of experiencing poor mental health, including depression and post-traumatic stress disorder. These conditions are associated with high rates of cardiovascular disease, in part due to low levels of physical activity (...

journal_title：BMJ open

authors： McKeon G,Steel Z,Wells R,Newby JM,Hadzi-Pavlovic D,Vancampfort D,Rosenbaum S

更新日期：2019-09-11 00:00:00

abstract：OBJECTIVES:The objective of this study is to examine the temporal trend of antiplatelet prescribing pattern during index hospitalisation discharge in Hong Kong (HK) acute coronary syndrome (ACS) population. DESIGN:The study is a retrospective observational cohort study. SETTING:The study retrieved data from electroni...

journal_title：BMJ open

authors： Lam AS,Yan BP,Lee VW

更新日期：2020-12-03 00:00:00

abstract：OBJECTIVE:Hepatitis B reactivation (HBr) is strongly associated with rituximab therapy. Guidelines advise hepatitis B screening and use of preventive nucleoside analogue (NA) in patients at risk. In this study, we examined screening trends, post-screening interventions and outcomes in patients receiving rituximab in li...

journal_title：BMJ open

authors： Haider M,Flocco G,Lopez R,Carey W

更新日期：2020-12-15 00:00:00

abstract：OBJECTIVES:We examined the level of agreement between biomedical and self-reported measurements of hypertension and diabetes in a Chinese national community sample, and explored associations of the agreement and possible contextual effects among provinces and geographic regions in China. DESIGN:Secondary analysis of a...

journal_title：BMJ open

authors： Ning M,Zhang Q,Yang M

更新日期：2016-01-04 00:00:00

abstract：OBJECTIVES:Increasing evidence suggests that low social support is associated with an elevated risk of coronary heart disease (CHD). Earlier studies in this field were conducted in predominantly middle-aged or older samples; thus, the associations reported previously may have been confounded by subclinical manifestatio...

journal_title：BMJ open

authors： Balog P,Janszky I,Chen H,Rafael B,Hemmingsson T,László KD

更新日期：2019-12-09 00:00:00

abstract：OBJECTIVES:Smoking prevalence is slow to reduce among Indigenous Australians of reproductive age. We analysed the relationships between age of smoking initiation, recalled initiation influences and self-assessment of smoking risks in Aboriginal smokers. DESIGN, SETTING AND PARTICIPANTS:A community-based cross-sectiona...

journal_title：BMJ open

authors： Gould GS,Watt K,West R,Cadet-James Y,Clough AR

更新日期：2016-07-07 00:00:00

abstract：OBJECTIVE:The aims of this study were to describe the experiences of senior students using mobile devices in a clinical setting while learning and interacting with clinical teachers, patients and each other, and to identify challenges that facilitated or impeded the use of such devices in the hospital. DESIGN:Interpre...

journal_title：BMJ open

authors： Rashid-Doubell F,Mohamed S,Elmusharaf K,O'Neill CS

更新日期：2016-05-03 00:00:00

abstract：OBJECTIVES:Atrial fibrillation (AF) is the most common cardiac rhythm disorder with a significant health burden. The aim of this study was to characterise patients with recently diagnosed AF and to estimate the rates of comorbidities and outcome events requiring hospitalisation in routine clinical practice. DESIGN:Pha...

journal_title：BMJ open

authors： Gallagher AM,van Staa TP,Murray-Thomas T,Schoof N,Clemens A,Ackermann D,Bartels DB

更新日期：2014-01-27 00:00:00

abstract：OBJECTIVES:Previous qualitative research investigating the experiences of women diagnosed with gestational diabetes (GD) has provided important insights into the development of behaviour change interventions. However, these studies often lack a theoretical underpinning. This study explored the use of the capability, op...

journal_title：BMJ open

authors： Boyd J,McMillan B,Easton K,Delaney B,Mitchell C

更新日期：2020-08-04 00:00:00

abstract：OBJECTIVE:To systematically review the literature for evidence of smoking and alcohol intake as independent risk factors for invasive pneumococcal disease (IPD). DESIGN:Systematic review. METHODS:MEDLINE (1946-May 2012) and EMBASE (1947-May 2012) were searched for studies investigating alcohol or smoking as risk fact...

journal_title：BMJ open

authors： Cruickshank HC,Jefferies JM,Clarke SC

更新日期：2014-06-20 00:00:00

abstract：OBJECTIVES:Cardiac rehabilitation (CR) improves outcomes after myocardial infarction (MI), but it is underused in China. The purpose of this study was to develop a set of quality indicators (QIs) to improve clinical practices and to confirm the measurability and performance of the developed QIs for CR in Chinese patien...

journal_title：BMJ open

authors： Zheng X,Zhang M,Zheng Y,Zhang Y,Wang J,Zhang P,Yang X,Li S,Ding R,Siqin G,Hou X,Chen L,Zhang M,Sun Y,Wu J,Yu B

更新日期：2020-12-30 00:00:00

abstract：OBJECTIVES:Explore the function of three specific modes of talk (discourse types) in decision-making processes. DESIGN:Ten real-life admissions of patients with critical illness were audio/video recorded and transcribed. Activity-type analysis (a qualitative discourse analytical method) was applied. SETTING:Interdisc...

journal_title：BMJ open

authors： Gundrosen S,Thomassen G,Wisborg T,Aadahl P

更新日期：2018-11-03 00:00:00