Abstract:
OBJECTIVES:Dyslipidaemia is a major risk factor to cardiovascular disease (CVD)--the leading cause of death worldwide. Limited data are available about the prevalence of various dyslipidaemia in Canada. The objective of this study is to describe the prevalence of various single and mixed dyslipidaemia within the Canadian population in a primary care setting. SETTING:A cross-sectional study, using the Canadian Primary Care Sentinel Surveillance Network (CPCSSN), was undertaken. PARTICIPANTS:Non-pregnant adults older than 20 years were included. OUTCOME MEASURES:Canadian guidelines were used to define dyslipidaemia. Descriptive statistics and multivariate regression analyses were conducted to compare the prevalence of single/mixed dyslipidaemia. RESULTS:134,074 individuals with a mean age of 59.2 (55.8% women) were identified. 34.8% of this population had no lipid abnormality, whereas 35.8%, 17.3% and 3.2% had abnormalities in one, two and three lipid components, respectively. Approximately 86% of these patients did not receive any lipid-lowering medication. Among the medication users (14%), approximately 12% were on statin monotherapy. Statin users (n=16,036) had a lower rate of low-density lipoprotein dyslipidaemia compared to non-medication users (3% vs 17%), whereas the prevalence of high-density lipoprotein (HDL) (20% vs 12%) and triglycerides (TG) (12% vs 7%) dyslipidaemia were higher in statin users. Statin users had a greater prevalence of HDL, TG and combined HDL-TG dyslipidaemia compared to non-medication users (OR 1.44, 95% CI 1.36 to 153), (OR 1.18, 95% CI 1.10 to 1.27) and (OR 1.30, 95% CI 1.22 to 1.38), respectively, (all p values<0.0001). CONCLUSIONS:One of every five patients in primary care settings in Canada is suffering from mixed dyslipidaemia. The overall prevalence of dyslipidaemia remains the same between treated and untreated groups, although the type of abnormal lipid component is considerably different. Among the CVD risk factors, obesity has the greatest effect on the prevalence of all types of dyslipidaemia.
journal_name
BMJ Openjournal_title
BMJ openauthors
Asghari S,Aref-Eshghi E,Godwin M,Duke P,Williamson T,Mahdavian Mdoi
10.1136/bmjopen-2015-007954subject
Has Abstractpub_date
2015-12-11 00:00:00pages
e007954issue
12issn
2044-6055pii
bmjopen-2015-007954journal_volume
5pub_type
杂志文章相关文献
BMJ Open文献大全abstract:INTRODUCTION:Ageing-related processes such as cellular senescence are believed to underlie the accumulation of diseases in time, causing (co)morbidity, including cancer, thromboembolism and stroke. Interfering with these processes may delay, stop or reverse morbidity. The aim of this study is to investigate the link be...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2020-039560
更新日期:2020-12-17 00:00:00
abstract:OBJECTIVE:To determine the extent of agreement and patterns of disagreement between wound swab and tissue samples in patients with an infected diabetic foot ulcer (DFU). DESIGN:Multicentre, prospective, cross-sectional study. SETTING:Primary and secondary care foot ulcer/diabetic outpatient clinics and hospital wards...
journal_title:BMJ open
pub_type: 杂志文章,多中心研究
doi:10.1136/bmjopen-2017-019437
更新日期:2018-01-31 00:00:00
abstract:OBJECTIVES:To define the core competencies essential for specialist training in neurocritical care in China. DESIGN:Modified Delphi method and nominal group (NG) technique. SETTING:National. PARTICIPANTS:A total of 1094 respondents from 33 provinces in China participated in the online survey. A NG of 11 members was ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-033441
更新日期:2020-01-06 00:00:00
abstract:INTRODUCTION:The incidence of head and neck cancer (HNC) in the UK is rising, with an average of 31 people diagnosed daily. Patients affected by HNC suffer significant short-term and long-term post-treatment morbidity as a result of dysphagia, which affects daily functioning and quality of life (QOL). Pretreatment swal...
journal_title:BMJ open
pub_type: 杂志文章,随机对照试验
doi:10.1136/bmjopen-2016-014167
更新日期:2017-03-27 00:00:00
abstract:INTRODUCTION:Preterm babies are among the highest users of parenteral nutrition (PN) of any patient group, but there is wide variation in commencement, duration, and composition of PN and uncertainty around which groups will benefit from early introduction. Recent studies in critically unwell adults and children sugges...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-029065
更新日期:2019-07-09 00:00:00
abstract:OBJECTIVE:We aimed to determine the key predictors of perinatal deaths using machine learning models compared with the logistic regression model. DESIGN:A secondary data analysis using the Kilimanjaro Christian Medical Centre (KCMC) Medical Birth Registry cohort from 2000 to 2015. We assessed the discriminative abilit...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2020-040132
更新日期:2020-10-19 00:00:00
abstract:OBJECTIVES:Our aim was to provide nationwide age-standardised rates (ASR) on the usage of endovascular coiling and neurosurgical clipping for unruptured intracranial aneurysm (UIA) treatment in Germany. SETTING:Nationwide observational study using the Diagnosis-Related-Groups (DRG) statistics for the years 2005-2009 (...
journal_title:BMJ open
pub_type: 杂志文章,多中心研究
doi:10.1136/bmjopen-2016-012294
更新日期:2017-01-17 00:00:00
abstract:OBJECTIVES:To evaluate the impact of a patient-specific national programme targeting older Australians and health professionals that aimed to increase use of emollient moisturisers to reduce to the risk of skin tears. DESIGN:A prospective cohort intervention. PARTICIPANTS:The intervention targeted 52 778 Australian G...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2020-039579
更新日期:2020-10-29 00:00:00
abstract:INTRODUCTION:Holistic healthcare considers the whole person-their body, mind, spirit and emotions-and has been associated with narrative medicine practice. Narrative medicine is medicine performed with narrative skill and has been offered as a model for humanism and effective medical practice. Narrative medicine interv...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-029588
更新日期:2019-08-02 00:00:00
abstract:OBJECTIVE:Older patients with hip fractures who are undergoing surgery are at high risk of significant mortality and morbidity including postoperative delirium. It is unclear whether different types of anaesthesia may reduce the incidence of postoperative delirium. This systematic review will investigate the impact of ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2017-020757
更新日期:2018-12-04 00:00:00
abstract:OBJECTIVES:The objective of this study was to investigate the role stressors, sociodemographic characteristics and job tasks of health surveillance assistants (HSAs) and to explore major predictors of role stressors and job satisfaction of HSAs in Malawi. SETTING:Data were collected from health centres and hospitals o...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2020-037000
更新日期:2020-11-14 00:00:00
abstract:OBJECTIVE:Increased physical activity (PA) may be beneficial for children with asthma. Knowledge about how to intervene and encourage children with asthma to be physically active is required. In the present study, we aimed to pilot a 6-week exercise intervention designed as active play and examine attendance rate, exer...
journal_title:BMJ open
pub_type: 临床试验,杂志文章
doi:10.1136/bmjopen-2015-009721
更新日期:2016-01-05 00:00:00
abstract:INTRODUCTION:The ongoing opioid epidemic has necessitated increasing prescriptions of buprenorphine, which is an evidence-based treatment for opioid use disorder, and also shown to reduce harms associated with unsafe opioid administration. A systematic review of perioperative management strategies for patients taking b...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-027374
更新日期:2019-05-22 00:00:00
abstract:OBJECTIVES:Ethiopia is a developing country striving to achieve universal health coverage using the health extension programme. There is limited evidence about Ethiopian women's satisfaction with their urban health extension programme. Thus, this study was aimed at assessing the level of women's satisfaction with their...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2020-039390
更新日期:2020-12-13 00:00:00
abstract:OBJECTIVES:Medical image analysis practices face challenges that can potentially be addressed with algorithm-based segmentation tools. In this study, we map the field of automatic MR brain lesion segmentation to understand the clinical applicability of prevalent methods and study designs, as well as challenges and limi...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2020-042660
更新日期:2021-01-29 00:00:00
abstract:OBJECTIVES:Given many countries' ageing populations, policymakers must consider how to mitigate or reduce health problems associated with old age, within budgetary constraints. Evidence of use of digital technology in delaying the onset of illness and reducing healthcare service use is mixed, with no clear consensus as...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2017-015839
更新日期:2017-07-21 00:00:00
abstract:PURPOSE:Despite the growing evidence that physical activity and familial factors play a role in low back pain (LBP), there is a lack of robust longitudinal studies that (1) investigate the types and dosages of physical activity that are protective or harmful for LBP, (2) employ objective measures of physical activity a...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-036301
更新日期:2020-07-28 00:00:00
abstract:INTRODUCTION:The mainstay treatment for reducing the symptoms of angina and long-term risk of heart attacks in patients with heart disease is stent implantation in the diseased coronary artery. While this procedure has revolutionised treatment, the incidence of secondary events remains a concern. These repeat events ar...
journal_title:BMJ open
pub_type: 杂志文章,随机对照试验
doi:10.1136/bmjopen-2016-012728
更新日期:2016-12-20 00:00:00
abstract:OBJECTIVES:Despite evidence for an association between the built environment and physical activity, less evidence exists regarding relations between the built environment and sedentary behaviour. This study investigated the extent to which objectively assessed and self-reported neighbourhood walkability, in addition to...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2015-009418
更新日期:2015-11-25 00:00:00
abstract:INTRODUCTION:Spondyloarthritis (SpA) is a heterogeneous spectrum of rheumatic diseases with either predominantly axial inflammatory symptoms of the spine and sacroiliac joints or predominantly peripheral arthritis. The two main entities of axial SpA (axSpA) are ankylosing spondylitis or non-radiographic axSpA (nr-axSpA...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2016-015536
更新日期:2017-07-10 00:00:00
abstract:OBJECTIVES:People who are marginalised (medically underserved) experience significant health disparities and their voices are often 'seldom heard'. Interventions to improve professional awareness and engagement with these groups are urgently needed. This study uses a co-production approach to develop an online digital ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-031548
更新日期:2019-09-17 00:00:00
abstract:INTRODUCTION:Cyclooxygenase 2 (COX-2) inhibitors have less upper gastrointestinal toxicity than traditional non-steroidal anti-inflammatory drugs (NSAIDs). However, both COX-2 inhibitors and traditional NSAIDs may be associated with adverse cardiovascular side effects. Data from randomised and observational studies sug...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2012-002295
更新日期:2013-01-29 00:00:00
abstract:INTRODUCTION:Maternal and perinatal death surveillance and response (MPDSR), or any related form of audit, is a systematic process used to prevent future maternal and perinatal deaths. While the existence of MPDSR policies is routinely measured, measurement and understanding of policy implementation has lagged behind. ...
journal_title:BMJ open
pub_type: 杂志文章,评审
doi:10.1136/bmjopen-2019-031328
更新日期:2019-11-27 00:00:00
abstract:OBJECTIVES:To investigate the impact of gender on multimorbidity in northern Iran. DESIGN:A cross-sectional analysis of the Golestan cohort data. SETTING:Golestan Province, Iran. STUDY POPULATION:49 946 residents (age 40-75 years) of Golestan Province, Iran. MAIN OUTCOME MEASURES:Researchers collected data related ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2016-013548
更新日期:2017-05-09 00:00:00
abstract:OBJECTIVES:Nursing home residents (NHRs) are frequently suffering from multimorbidity, functional and cognitive impairment, often leading to hospital admissions. Studies have found that male NHRs are more often hospitalised. The influence of age is inconclusive. We aimed to investigate the epidemiology of hospitalisati...
journal_title:BMJ open
pub_type: 杂志文章,评审
doi:10.1136/bmjopen-2016-011912
更新日期:2016-10-08 00:00:00
abstract:OBJECTIVE:This study evaluated knowledge, opinions and compliance related to Uganda's comprehensive smoke-free law among hospitality venues in Kampala Uganda. DESIGN:This multi-method study presents cross-sectional findings of the extent of compliance in the early phase of Uganda's comprehensive smoke-free law (2 mont...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2017-017601
更新日期:2018-01-05 00:00:00
abstract:INTRODUCTION:Children who have experienced abuse and neglect are at increased risk of mental and physical health problems throughout life. This places an enormous burden on individuals, families and society in terms of health services, education, social care and judiciary sectors. Evidence suggests that early intervent...
journal_title:BMJ open
pub_type: 杂志文章,随机对照试验
doi:10.1136/bmjopen-2017-020066
更新日期:2018-03-14 00:00:00
abstract:OBJECTIVE:To identify the advantages and disadvantages that group practices have on patients, physicians and healthcare systems. STUDY DESIGN:A scoping review was performed based on the methodology proposed by Arksey and O'Malley, and refined by Levac et al. Titles and abstracts were screened by two reviewers. A quant...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2020-041579
更新日期:2021-01-08 00:00:00
abstract:OBJECTIVES:Physical activity is widely recommended in the treatment and management of cystic fibrosis (CF). Despite the numerous physical and psychological benefits, many young people with CF are not achieving the recommended levels of physical activity. The aim of this systematic review was to identify and synthesise ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-035261
更新日期:2020-02-20 00:00:00
abstract:INTRODUCTION:As a combination of visual stimulation and motor imagery, mirror visual feedback (MVF) is an effective treatment for motor impairment after stroke; however, few studies have investigated its effects on relevant cognitive processes such as visual perception and motor imagery. Camera-based MVF (camMVF) overc...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-022828
更新日期:2019-03-03 00:00:00