Addressing clinical equipoise for hearing devices: the qualitative COACH (q-COACH) study protocol for Australian stakeholder involvement in the design of a randomised controlled trial.

abstract：INTRODUCTION:The large number of treatment modalities for patients diagnosed with Menière's disease (MD) complicates the selection of the best available treatment as the comparative efficacy of these interventions is not clear. We aim to identify the treatment or treatments with the highest efficacy of current pharmaco...

journal_title：BMJ open

authors： van Esch BF,van der Zaag-Loonen HJ,Bruintjes TD,van Benthem PP

更新日期：2016-06-09 00:00:00

abstract：OBJECTIVE:This study aimed to build an understanding of how the process of singing impacts on those who are affected by cancer, including patients, staff, carers and those who have been bereaved. DESIGN:A qualitative study, informed by a grounded theory approach. SETTING AND PARTICIPANTS:Patients with cancer, staff, ...

journal_title：BMJ open

authors： Warran K,Fancourt D,Wiseman T

更新日期：2019-01-07 00:00:00

abstract：OBJECTIVES:To measure work-related burnout in all groups of health service staff during the COVID-19 pandemic and to identify factors associated with work-related burnout. DESIGN:Cross-sectional staff survey. SETTING:All staff grades and types across primary and secondary care in a single National Health Service orga...

journal_title：BMJ open

authors： Gemine R,Davies GR,Tarrant S,Davies RM,James M,Lewis K

更新日期：2021-01-28 00:00:00

abstract：OBJECTIVES:This study aimed to investigate whether violent and non-violent offending were related to elevated risk of suicide. We also investigated whether the risk was higher among those with repeated offences and how experiences of substance misuse and suicide attempt modified the relationship. DESIGN:A nationwide p...

journal_title：BMJ open

authors： Stenbacka M,Romelsjö A,Jokinen J

更新日期：2014-02-03 00:00:00

abstract：INTRODUCTION:Carotid intima-media thickness (CIMT) is a surrogate marker of atherosclerosis that is measured in adults and children to better understand the natural history of cardiovascular disease (CVD). In adults, CIMT is predictive of myocardial infarction and stroke. In children and adolescents, CIMT is used to as...

journal_title：BMJ open

authors： Epure AM,Leyvraz M,Mivelaz Y,Di Bernardo S,da Costa BR,Chiolero A,Sekarski N

更新日期：2018-06-04 00:00:00

abstract：:The serial interval is the time between symptom onsets in an infector-infectee pair. The generation time, also known as the generation interval, is the time between infection events in an infector-infectee pair. The serial interval and the generation time are key parameters for assessing the dynamics of a disease. A n...

journal_title：BMJ open

authors： Griffin J,Casey M,Collins Á,Hunt K,McEvoy D,Byrne A,McAloon C,Barber A,Lane EA,More S

更新日期：2020-11-23 00:00:00

abstract：INTRODUCTION:Current management of primary spontaneous pneumothorax (PSP) is variable, with little evidence from randomised controlled trials to guide treatment. Guidelines emphasise intervention in many patients, which involves chest drain insertion, hospital admission and occasionally surgery. However, there is evide...

journal_title：BMJ open

authors： Brown SG,Ball EL,Perrin K,Read CA,Asha SE,Beasley R,Egerton-Warburton D,Jones PG,Keijzers G,Kinnear FB,Kwan BC,Lee YC,Smith JA,Summers QA,Simpson G,PSP Study Group.

更新日期：2016-09-13 00:00:00

abstract：INTRODUCTION:Ageing--along with its associated physiological and pathological changes--places individuals at a higher risk of multimorbidity and treatment-related complications. Today, polypharmacy, a common and important problem related to drug use, occurs subsequent to this multimorbidity in the elderly in all popula...

journal_title：BMJ open

authors： Mortazavi SS,Shati M,Keshtkar A,Malakouti SK,Bazargan M,Assari S

更新日期：2016-03-24 00:00:00

abstract：OBJECTIVE:To examine the associations between consumption of sweetened products, daytime sleepiness (DS) and psychological distress (PD) in a Catholic Middle-Eastern Canadian community, and to test the hypothesis that the association between DS and consumption of sweetened products is mediated by PD. DESIGN:A cross-se...

journal_title：BMJ open

authors： Moubarac JC,Cargo M,Receveur O,Daniel M

更新日期：2013-02-13 00:00:00

abstract：OBJECTIVES:Anxiety disorders (ADs) are common after traumatic brain injury (TBI). However, the risk factors of new-onset ADs remain unclear. This study was aimed at evaluating the incidence and risk factors for new-onset ADs, including pre-existing hyperlipidaemia and three major comorbidities (diabetes mellitus, hyper...

journal_title：BMJ open

authors： Ho CH,Hsieh KY,Liang FW,Li CJ,Wang JJ,Chio CC,Chang CH,Kuo JR

更新日期：2014-07-17 00:00:00

abstract：OBJECTIVES:To evaluate the health outcomes and economics associated with the current guidance relating to the prevention of falls in the elderly through vitamin D supplementation. SETTING:UK. PARTICIPANTS:UK population aged 60 years and above. INTERVENTIONS:A Markov health state transition model simulated patient tr...

journal_title：BMJ open

authors： Poole CD,Smith J,Davies JS

更新日期：2015-09-29 00:00:00

abstract：OBJECTIVES:To investigate the prevalence of mild cognitive impairment and the relationship with plasma aluminium among aluminium workers. DESIGN:This was a cross-sectional case-control study in the SH Aluminium Factory, China. SETTING:The university and affiliated hospital cooperated in the study. PARTICIPANTS:There...

journal_title：BMJ open

authors： Meng H,Wang S,Guo J,Zhao Y,Zhang S,Zhao Y,Niu Q

更新日期：2019-06-16 00:00:00

abstract：OBJECTIVES:In the context of tightening fiscal budgets and increased commissioning responsibility, local decision-makers across the UK healthcare sector have found themselves in charge of the implementation and evaluation of a greater range of healthcare interventions and services. However, there is often little experi...

journal_title：BMJ open

authors： Hinde S,Bojke L,Richardson G

更新日期：2019-11-21 00:00:00

abstract：OBJECTIVES:For characterisation of mineral bone disease in chronic kidney disease (CKD), laboratory surrogates have been suggested. This observational should investigate the association of total and skeletal alkaline phosphatase (AP) with mortality of patients undergoing maintenance renal replacement therapy. SETTING:...

journal_title：BMJ open

authors： Beige J,Wendt R,Girndt M,Queck KH,Fiedler R,Jehle P

更新日期：2014-02-27 00:00:00

abstract：INTRODUCTION:Case management allows us to respond to the complex needs of a vulnerable clientele through a structured approach that promotes enhanced interaction between partners. Syntheses on the subject converge towards a need for a better description of the relationships between programmes and their local context, a...

journal_title：BMJ open

authors： Hudon C,Chouinard MC,Couture M,Brousselle A,Couture EM,Dubois MF,Fortin M,Freund T,Loignon C,Mireault J,Pluye P,Roberge P,Rodriguez C

更新日期：2014-12-02 00:00:00

abstract：INTRODUCTION:Recreational drug use in the nightlife setting carries the risk of many negative consequences, such as violence, injuries, aberrant driving and sexual risk-taking. The aim of this study is to investigate recreational drug use and user characteristics among people visiting licensed premises, for example, ni...

journal_title：BMJ open

authors： Nordfjærn T,Edland-Gryt M,Bretteville-Jensen AL,Buvik K,Gripenberg J

更新日期：2016-04-22 00:00:00

abstract：OBJECTIVE:The aim of this pilot study was to determine risk factors, including Staphylococcus aureus nasal carriage, for dermatitis in submariners during a submarine patrol. PARTICIPANTS AND METHODS:36 submariners undertaking a submerged 6-week patrol participated in the study. Severity of dermatitis and its impact wa...

journal_title：BMJ open

authors： Flaxman A,Allen E,Lindemann C,Yamaguchi Y,O'Shea MK,Fallowfield JL,Lindsay M,Gunner F,Knox K,Wyllie DH

更新日期：2016-06-02 00:00:00

abstract：INTRODUCTION:Down syndrome results in neuromotor impairment that affects selective motor control, compromising the acquisition of motor skills and functional independence. The aim of the proposed study is to evaluate and compare the effects of multiple-monopolar anodal transcranial direct current stimulation and sham s...

journal_title：BMJ open

authors： Lopes JBP,Grecco LAC,Moura RCF,Lazzari RD,Duarte NAC,Miziara I,Melo GEL,Dumont AJL,Galli M,Santos Oliveira C

更新日期：2017-08-11 00:00:00

abstract：OBJECTIVES:To assess the communication potential of three-dimensional (3D) patient-specific models of congenital heart defects and their acceptability in clinical practice for cardiology consultations. DESIGN:This was a questionnaire-based study in which participants were randomised into two groups: the 'model group' ...

journal_title：BMJ open

authors： Biglino G,Capelli C,Wray J,Schievano S,Leaver LK,Khambadkone S,Giardini A,Derrick G,Jones A,Taylor AM

更新日期：2015-04-30 00:00:00

abstract：OBJECTIVE:To investigate the incidence of primary care presentations for herpes zoster (zoster) in a representative New Zealand population and to evaluate the utilisation of primary healthcare services following zoster diagnosis. DESIGN:A cross-sectional retrospective cohort study used a natural language processing so...

journal_title：BMJ open

authors： Turner NM,MacRae J,Nowlan ML,McBain L,Stubbe MH,Dowell A

更新日期：2018-05-31 00:00:00

abstract：INTRODUCTION:Current perspectives present feedback as a dynamic, dialogic process. It is widely accepted that feedback can have an impact on workplace performance, however, how dialogic feedback is enacted with the learner in authentic healthcare settings is less apparent. This paper seeks to describe the design and de...

journal_title：BMJ open

authors： Ossenberg C,Mitchell M,Henderson A

更新日期：2020-06-08 00:00:00

abstract：INTRODUCTION:Approximately 5%-20% of reproductive women suffer from polycystic ovary syndrome (PCOS). Auricular points acupressure (AA) may serve as alternative management for PCOS for its benefits in both physical and psychological well-being. However, the effects of AA for insulin resistance (IR) in overweight/obese ...

journal_title：BMJ open

authors： Li Y,Hou L,Wang Y,Xie L,Zhang M,Pan Z,Li Y,Ding Y,Sun M,Qu Y,Liu S

更新日期：2019-05-28 00:00:00

abstract：OBJECTIVES:Outcome and comparator choice strongly determine the validity and implementation of clinical trial results. We aimed to assess outcome and comparator choice in intervention studies on molar incisor hypomineralisation (MIH) using systematic review and social network analysis (SNA). DESIGN AND DATA SOURCES:Me...

journal_title：BMJ open

authors： Elhennawy K,Krois J,Jost-Brinkmann PG,Schwendicke F

更新日期：2019-08-02 00:00:00

abstract：OBJECTIVES:In response to public health concern about effects of arson at solid waste management plants in July 2012, we analysed vital statistics data to evaluate any potential effect on pregnancies at different gestational ages of pollutants emitted from the landfill on fire. SETTING:A community living near the larg...

journal_title：BMJ open

authors： Mazzucco W,Tavormina E,Macaluso M,Marotta C,Cusimano R,Alba D,Costantino C,Grammauta R,Cernigliaro A,Scondotto S,Vitale F

更新日期：2019-07-04 00:00:00

abstract：INTRODUCTION:The role of adjuvant chemotherapy after radical radiotherapy (RT) or chemoradiotherapy (CRT) in cervical cancer awaits further confirmation. Evidences have shown that persistent human papilloma virus (HPV) DNA in exfoliated cell post-RT is a potential biomarker of subclinical residual disease and thus incr...

journal_title：BMJ open

authors： Wang Y,Ouyang Y,Su J,Liu J,Cai Q,Xu Q,Bai Z,Cao X

更新日期：2019-10-07 00:00:00

abstract：OBJECTIVE:The evaluation of discomfort in paediatric research is scarcely evidence-based. In this study, we make a start in describing children's self-reported discomfort during common medical research procedures and compare this with discomfort during dental check-ups which can be considered as a reference level of a ...

journal_title：BMJ open

authors： Staphorst MS,Benninga MA,Bisschoff M,Bon I,Busschbach JJV,Diederen K,van Goudoever JB,Haarman EG,Hunfeld JAM,Jaddoe VVW,de Jong KJM,de Jongste JC,Kindermann A,Königs M,Oosterlaan J,Passchier J,Pijnenburg MW,Reneman L,

更新日期：2017-08-01 00:00:00

abstract：INTRODUCTION:Multimorbidity is a major challenge for current healthcare systems and professionals. From the different approaches that have been proposed to analyse this issue, the hypothesis of the existence of association patterns of different chronic conditions is gaining visibility. In addition, multimorbidity can b...

journal_title：BMJ open

authors： Baré M,Herranz S,Jordana R,Gorgas MQ,Ortonobes S,Sevilla D,De Jaime E,Ibarra O,Martín C,MoPIM study group.

更新日期：2020-01-26 00:00:00

abstract：INTRODUCTION:Smell and taste of milk are not generally considered when tube feeding preterm infants. Preterm infants have rapid growth, particularly of the brain, and high caloric needs. Enteral feeding is often poorly tolerated which may lead to growth failure and long-term neurodevelopmental impairment. Smell and tas...

journal_title：BMJ open

authors： Beker F,Macey J,Liley H,Hughes I,Davis PG,Twitchell E,Jacobs S

更新日期：2019-07-17 00:00:00

abstract：OBJECTIVE:Changing patient demographics make it ever more challenging to maintain the quality and safety of care. One approach to addressing this is the development of training for generalist doctors who can take a more holistic approach to care. The purpose of the work we report here is to consider whether a broad-bas...

journal_title：BMJ open

authors： Bullock A,Webb KL,Muddiman E,MacDonald J,Allery L,Pugsley L

更新日期：2018-04-12 00:00:00

abstract：OBJECTIVES:To conduct a fully independent, external validation of a research study based on one electronic health record database using a different database sampling from the same population. DESIGN:Retrospective cohort analysis of β-blocker therapy and all-cause mortality in patients with cancer. SETTING:Two UK nati...

journal_title：BMJ open

authors： Springate DA,Ashcroft DM,Kontopantelis E,Doran T,Ryan R,Reeves D

更新日期：2015-04-13 00:00:00