Defining polypharmacy in the elderly: a systematic review protocol.

abstract：INTRODUCTION:Although cardiologists were 'late-comers' to the multidisciplinary team-contributing to the complex care of patients with Duchenne muscular dystrophy (DMD), they now recognise the importance of systematic cardiac surveillance and timely therapy to prolonged survival in patients with DMD. Empirical deployme...

journal_title：BMJ open

authors： Bourke JP,Watson G,Muntoni F,Spinty S,Roper H,Guglieri M,Speed C,McColl E,Chikermane A,Jayawant S,Adwani S,Willis T,Wilkinson J,Bryant A,Chadwick T,Wood R,Bushby K,DMD Heart Protection study group.

更新日期：2018-12-19 00:00:00

abstract：OBJECTIVE:The current study aimed to better understand trends and risk factors associated with non-fatal drowning of infants and children in the USA using two large, national databases. METHODS:A secondary data analysis was conducted using the National Inpatient Sample and the Nationwide Emergency Department Sample da...

journal_title：BMJ open

authors： Felton H,Myers J,Liu G,Davis DW

更新日期：2015-12-15 00:00:00

abstract：OBJECTIVES:To derive a tool to determine Urgent Care Center (UCC) crowding and investigate the association between different levels of UCC overcrowding and negative patient care outcomes. DESIGN:Prospective pilot study. SETTING:Single centre study in the USA. PARTICIPANTS:3565 patients who registered at UCC during t...

journal_title：BMJ open

authors： Wang H,Robinson RD,Cowden CD,Gorman VA,Cook CD,Gicheru EK,Schrader CD,Jayswal RD,Zenarosa NR

更新日期：2015-04-14 00:00:00

abstract：INTRODUCTION:Physical activity (PA) has diverse benefits for physical and mental health and can reduce symptoms of mental illness. Adults with mental illness face practical, psychosocial and socioeconomic barriers to adopting and maintaining PA, and it is unclear how to effectively promote PA in this group. Supervised ...

journal_title：BMJ open

authors： Chapman JJ,Suetani S,Siskind D,Kisely S,Breakspear M,Byrne JH,Patterson S

更新日期：2018-09-08 00:00:00

abstract：BACKGROUND:COVID-19 has posed several medical, psychosocial and economic impacts among the majority of the society. The ambiguity of its transmission, the intense desire of self-protection, family, and friends, the unknown impact of catching the disease itself, unstoppable spread, the panic and outright misinformation ...

journal_title：BMJ open

authors： Yitayih Y,Lemu YK,Mekonen S,Mecha M,Ambelu A

更新日期：2021-01-06 00:00:00

abstract：OBJECTIVE:This study aimed to evaluate the factor structure of the Chinese version of the 22-item Zarit Burden Interview (ZBI) among family caregivers of patients with schizophrenia in China. METHODS:Using one-stage cluster-sampling design, 324 primary caregivers of patients with schizophrenia in Ningxiang County, Hun...

journal_title：BMJ open

authors： Tang B,Yu Y,Liu Z,Lin M,Chen Y,Zhao M,Xiao S

更新日期：2017-09-29 00:00:00

abstract：OBJECTIVES:Literature on associations between female genital mutilation/cutting (FGM/C) and fistula points to a common belief that FGM/C predisposes women to developing fistula. This study explores this association using nationally representative survey data. DESIGN:A secondary statistical analysis of cross-sectional ...

journal_title：BMJ open

authors： Matanda DJ,Sripad P,Ndwiga C

更新日期：2019-07-29 00:00:00

abstract：BACKGROUND:Kawasaki disease (KD) is a self-limited acute systemic vasculitis of unknown aetiology that predominantly affects infants and young children eventually associated with immunological abnormalities. Coeliac disease (CD) is an inflammatory autoimmune disease characterised by a permanent gluten intolerance, whic...

journal_title：BMJ open

authors： Dos Santos Domingues A,Selleski N,Uenishi RH,Medeiros Ribeiro de Magalhães C,Gandolfi L,Pratesi CB

更新日期：2018-02-14 00:00:00

abstract：OBJECTIVES:Few studies of tornado injuries have considered differences related to damage levels and Enhanced-Fujita (EF) scale ratings. This study aimed to evaluate the pattern, spectrum and geographical distribution of injuries related to the Yancheng tornado and provide guidelines for effective emergency medical stra...

journal_title：BMJ open

authors： Deng Q,Lv Y,Xue C,Kang P,Dong J,Zhang L

更新日期：2018-06-22 00:00:00

abstract：INTRODUCTION:Secondary prevention drugs for cardiac disease have been demonstrated by clinical trials to be effective in reducing future cardiovascular and mortality events (WAMACH is the Western Australian Medication Adherence and Costs in Heart disease study). Hence, most countries have adopted health policies and gu...

journal_title：BMJ open

authors： Gunnell AS,Knuiman MW,Geelhoed E,Hobbs MS,Katzenellenbogen JM,Hung J,Rankin JM,Nedkoff L,Briffa TG,Ortiz M,Gillies M,Cordingley A,Messer M,Gardner C,Lopez D,Atkins E,Mai Q,Sanfilippo FM

更新日期：2014-09-18 00:00:00

abstract：OBJECTIVES:The aim of this study was to develop a single blood test that could determine gestational age and estimate the risk of preterm birth by measuring serum metabolites. We hypothesised that serial metabolic modelling of serum analytes throughout pregnancy could be used to describe fetal gestational age and proje...

journal_title：BMJ open

authors： Sylvester KG,Hao S,You J,Zheng L,Tian L,Yao X,Mo L,Ladella S,Wong RJ,Shaw GM,Stevenson DK,Cohen HJ,Whitin JC,McElhinney DB,Ling XB

更新日期：2020-12-02 00:00:00

abstract：OBJECTIVES:To investigate the relationship between low-density lipoprotein cholesterol (LDL-C) and all-cause mortality among middle-aged and elderly Chinese population. DESIGN:Prospective cohort study. SETTING:This study used data from the China Health and Retirement Longitudinal Study. PARTICIPANTS:Middle-aged and ...

journal_title：BMJ open

authors： Zhou L,Wu Y,Yu S,Shen Y,Ke C

更新日期：2020-08-16 00:00:00

abstract：OBJECTIVE:To explore the views of sick doctors on the obstacles preventing them returning to work. DESIGN:Qualitative study. SETTING:Single participating centre recruiting doctors from all over the UK. PARTICIPANTS:Doctors who had been away from work for at least 6 months with physical or mental health problems, dru...

journal_title：BMJ open

authors： Henderson M,Brooks SK,Del Busso L,Chalder T,Harvey SB,Hotopf M,Madan I,Hatch S

更新日期：2012-10-15 00:00:00

abstract：OBJECTIVES:To analyse the clinical features, inflammatory markers and radiographs of community-acquired pneumonia (CAP) cases with lobe or multi foci infiltration; with a special focus on factors which allow the differential diagnosis of viral and mycoplasma pneumonia. SETTING:Retrospective chart review of CAP cases i...

journal_title：BMJ open

authors： Guo WL,Wang J,Zhu LY,Hao CL

更新日期：2015-01-16 00:00:00

abstract：INTRODUCTION:Α substantial corpus of literature has sought to describe the information-seeking behaviour of patients with cancer. Yet, available evidence comes mainly from cross-sectional studies, which provide 'snapshots' of patients' information needs and information-seeking styles at a single time point. Only a few ...

journal_title：BMJ open

authors： Germeni E,Bianchi M,Valcarenghi D,Schulz PJ

更新日期：2015-10-06 00:00:00

abstract：OBJECTIVES:To identify the differential effects of patient, health service, temporal and geographic factors on length of stay (LOS) for chronic obstructive pulmonary disease (COPD)-related admissions. DESIGN:We used stratified Cox proportional hazard model to evaluate the association between LOS and patient, health se...

journal_title：BMJ open

authors： Agboado G,Peters J,Donkin L

更新日期：2012-09-01 00:00:00

abstract：INTRODUCTION:Chronic inguinal pain is a frequently occurring problem in athletes. A diagnosis of inguinal disruption is performed by exclusion of other conditions causing groin pain. Up to now, conservative medical management is considered to be the primary treatment for this condition. Relevant large and prospective c...

journal_title：BMJ open

authors： Voorbrood CE,Goedhart E,Verleisdonk EJ,Sanders F,Naafs D,Burgmans JP

更新日期：2016-01-06 00:00:00

abstract：OBJECTIVE:To estimate the costs and outcomes associated with treating non-asthmatic adults (nor suffering from other lung-disease) presenting to primary care with acute lower respiratory tract infection (ALRTI) with oral corticosteroids compared with placebo. DESIGN:Cost-consequence analysis alongside a randomised con...

journal_title：BMJ open

authors： Moure-Fernandez A,Hollinghurst S,Carroll FE,Downing H,Young G,Brookes S,May M,El-Gohary M,Harnden A,Kendrick D,Lafond N,Little P,Moore M,Orton E,Thompson M,Timmins D,Wang K,Hay AD

更新日期：2020-02-18 00:00:00

abstract：OBJECTIVES:To determine the availability of continuous positive airway pressure (CPAP) and to provide an overview of its use in neonatal units in government hospitals across India. SETTING:Cross-sectional cluster survey of a nationally representative sample of government hospitals from across India. PRIMARY OUTCOMES:...

journal_title：BMJ open

authors： Dewez JE,Nangia S,Chellani H,White S,Mathai M,van den Broek N

更新日期：2020-02-28 00:00:00

abstract：INTRODUCTION:The need for organs is comparatively higher among people of Indian origin due to the higher prevalence of end-stage organ failure. In spite of the higher need, they have a lower number of organ donors. Studies have been carried out among people of Indian origin living globally to understand the reasons for...

journal_title：BMJ open

authors： Vincent BP,Randhawa G,Cook E

更新日期：2020-06-21 00:00:00

abstract：PURPOSE:Acute-on-chronic liver failure (ACLF) is a clinical syndrome with high short-term mortality, unclear mechanism and controversial diagnosis criteria. The Chinese Acute-on-Chronic Liver Failure (CATCH-LIFE) study has been conducted in China to fill the gaps. In the first phase (the CATCH-LIFE investigation cohort...

journal_title：BMJ open

authors： Qiao L,Wang X,Deng G,Huang Y,Chen J,Meng Z,Zheng X,Shi Y,Qian Z,Liu F,Gao Y,Lu X,Liu J,Gu W,Zhang Y,Wang T,Wu D,Dong F,Sun X,Li H

更新日期：2021-01-08 00:00:00

abstract：OBJECTIVES:CT colonography (CTC) may be an acceptable test for colorectal cancer screening but bowel preparation can be a barrier to uptake. This study tested the hypothesis that prospective screening invitees would prefer full-laxative preparation with higher sensitivity and specificity for polyps, despite greater bur...

journal_title：BMJ open

authors： Ghanouni A,Halligan S,Taylor SA,Boone D,Plumb A,Stoffel S,Morris S,Yao GL,Zhu S,Lilford R,Wardle J,von Wagner C

更新日期：2014-04-03 00:00:00

abstract：INTRODUCTION:Diabetic macular oedema (DMO) and proliferative diabetic retinopathy (PDR) are the major causes of sight loss in people with diabetes. Due to the increased prevalence of diabetes, the workload related to these complications is increasing making it difficult for Hospital Eye Services (HSE) to meet demands. ...

journal_title：BMJ open

authors： Lois N,Cook J,Aldington S,Waugh N,Mistry H,Sones W,McAuley D,Aslam T,Bailey C,Chong V,Ghanchi F,Scanlon P,Sivaprasad S,Steel D,Styles C,McNally C,Rice R,Prior L,Azuara-Blanco A,EMERALD Study Group.

更新日期：2019-06-28 00:00:00

abstract：OBJECTIVE:To evaluate sex-specific and age-specific associations of active living environments (ALEs) with premature cardiometabolic mortality. DESIGN:Population-based retrospective cohort study. SETTING:Residential neighbourhoods (1000-metre circular buffers from the centroids of dissemination areas) across Canada f...

journal_title：BMJ open

authors： Mah SM,Sanmartin C,Riva M,Dasgupta K,Ross NA

更新日期：2020-11-20 00:00:00

abstract：OBJECTIVE:To test the hypothesis that cancer mortality rates among the Moluccan-Dutch, the oldest non-Western migrant group to arrive in the Netherlands after the Second World War, are similar to those in the general Dutch population. DESIGN:Population-based retrospective study. SETTING:Data from the national cause o...

journal_title：BMJ open

authors： van der Wal JM,Bodewes A,Agyemang C,Kunst A

更新日期：2019-08-15 00:00:00

abstract：OBJECTIVE:To review and summarise the available literature regarding breastfeeding experiences of medical students, residents and physicians. ELIGIBILITY CRITERIA:Articles of any design, including non-peer reviewed data that examine the experiences of breast feeding of medical students, residents and staff physicians....

journal_title：BMJ open

authors： Frolkis A,Michaud A,Nguyen KT,Bruton Joe M,Lithgow K,Ruzycki SM

更新日期：2020-10-15 00:00:00

abstract：INTRODUCTION:Frailty is associated with reduced functional capacity, decreased resistance to stressors and is predictive of a range of adverse health outcomes, including dependency, hospitalisation and mortality. Early identification of frailty may prevent, reduce and postpone adverse health outcomes. However, there is...

journal_title：BMJ open

authors： Shears M,McGolrick D,Waters B,Jakab M,Boyd JG,Muscedere J

更新日期：2017-12-26 00:00:00

abstract：INTRODUCTION:Warfarin is an effective anticoagulant and the only oral anticoagulant available for patients with mechanical heart valves. The prothrombin time and the associated international normalised ratio (INR) are routinely tested to monitor the response to anticoagulation therapy in patients. Patients who undergo ...

journal_title：BMJ open

authors： Zhu Z,Li Y,Meng X,Han J,Li Y,Liu K,Shen J,Qin Y,Zhang H

更新日期：2019-12-05 00:00:00

abstract：INTRODUCTION:The acceptability and efficacy of existing ready-to-use supplementary and therapeutic foods has been low in Cambodia, thus limiting success in preventing and treating malnutrition among Cambodian children. In that context, UNICEF and IRD have developed a locally produced, multiple micronutrient fortified l...

journal_title：BMJ open

authors： Borg B,Mihrshahi S,Griffin M,Chamnan C,Laillou A,Wieringa FT

更新日期：2017-09-06 00:00:00

abstract：OBJECTIVES:Although successful airway management is essential for emergency trauma care, comprehensive studies are limited. We sought to characterise current trauma care practice of airway management in the emergency departments (EDs) in Japan. DESIGN:Analysis of data from a prospective, observational, multicentre reg...

journal_title：BMJ open

authors： Nakao S,Kimura A,Hagiwara Y,Hasegawa K,Japanese Emergency Medicine Network Investigators.

更新日期：2015-02-04 00:00:00