Frailty measurement and outcomes in interventional studies: protocol for a systematic review of randomised control trials.

abstract：PURPOSE:Cardiovascular disease (CVD) is a major challenge to global health. The same epidemiological transition scenario is replayed as countries develop, but with variations based on environment, culture and ethnic mixture. The Baependi Heart Study was set up in 2005 to develop a longitudinal family-based cohort study...

journal_title：BMJ open

authors： Egan KJ,von Schantz M,Negrão AB,Santos HC,Horimoto AR,Duarte NE,Gonçalves GC,Soler JM,de Andrade M,Lorenzi-Filho G,Vallada H,Taporoski TP,Pedrazzoli M,Azambuja AP,de Oliveira CM,Alvim RO,Krieger JE,Pereira AC

更新日期：2016-10-21 00:00:00

abstract：OBJECTIVE:To determine the feasibility of a randomised controlled trial (RCT) assessing the effects of an experience-based website as a resource for the self-management of chronic asthma. DESIGN AND SETTING:Feasibility, single-blind RCT in 2 regions of England. Randomisation used computer-generated random number seque...

journal_title：BMJ open

authors： Newhouse N,Martin A,Jawad S,Yu LM,Davoudianfar M,Locock L,Ziebland S,Powell J

更新日期：2016-12-28 00:00:00

abstract：OBJECTIVES:We conducted a systematic survey of the methodological literature to identify recommended approaches for how and what randomised clinical trial (RCT) authors should report on missing participant data and, on the basis of these approaches, to propose guidance for RCT authors. METHODS:We defined missing parti...

journal_title：BMJ open

authors： Akl EA,Shawwa K,Kahale LA,Agoritsas T,Brignardello-Petersen R,Busse JW,Carrasco-Labra A,Ebrahim S,Johnston BC,Neumann I,Sola I,Sun X,Vandvik P,Zhang Y,Alonso-Coello P,Guyatt GH

更新日期：2015-12-30 00:00:00

abstract：INTRODUCTION:Little is known about the applicability of mindfulness-based interventions in Spanish adults with overweight/obesity. The objective of the present study protocol is to describe the methods that will be used in a cluster randomised trial (CRT) that aims to evaluate the effectiveness of a mindfulness eating ...

journal_title：BMJ open

authors： Morillo Sarto H,Barcelo-Soler A,Herrera-Mercadal P,Pantilie B,Navarro-Gil M,Garcia-Campayo J,Montero-Marin J

更新日期：2019-11-21 00:00:00

abstract：INTRODUCTION:Glaucoma is the second leading cause of age-related vision loss worldwide; it is an umbrella term that is used to describe a set of complex ocular disorders with a multifactorial aetiology. Both genetic and lifestyle risk factors for glaucoma are well established. Thus far, however, systematic reviews on t...

journal_title：BMJ open

authors： Asefa NG,Neustaeter A,Jansonius NM,Snieder H

更新日期：2018-02-28 00:00:00

abstract：OBJECTIVES:Respiratory symptoms are associated with spirometry results but more strongly with smoking history, suggesting that alterations in the lung other than those revealed by spirometry contribute to cause symptoms. Smoking may cause obstruction of peripheral airways that is poorly detected by spirometry. The slop...

journal_title：BMJ open

authors： Olofson JY,Houltz B,Nilsson Tengelin M,Bake B

更新日期：2012-11-27 00:00:00

abstract：OBJECTIVE:To describe help seeking behaviour from a medical doctor and antimicrobial use for common infections among rural residents of Anhui province, China. DESIGN:A cross-sectional retrospective household survey. SETTING:12 administrative villages from rural Anhui, China. PARTICIPANTS:2760 rural residents selecte...

journal_title：BMJ open

authors： Chai J,Coope C,Cheng J,Oliver I,Kessel A,Hu Z,Wang D

更新日期：2019-04-11 00:00:00

abstract：OBJECTIVES:To determine whether there was variation in nurse staffing across hospitals in Queensland prior to implementation of nurse-to-patient ratio legislation targeting medical-surgical wards, and if so, the extent to which nurse staffing variation was associated with poor outcomes for patients and nurses. DESIGN:...

journal_title：BMJ open

authors： McHugh MD,Aiken LH,Windsor C,Douglas C,Yates P

更新日期：2020-09-06 00:00:00

abstract：INTRODUCTION:Orthotopic liver transplantation (OLT) has emerged as the mainstay of treatment for end-stage liver disease. In an attempt to improve the availability of donor allografts and reduce waiting list mortality, graft acceptance criteria were extended increasingly over the decades. The use of extended criteria d...

journal_title：BMJ open

authors： Czigany Z,Schöning W,Ulmer TF,Bednarsch J,Amygdalos I,Cramer T,Rogiers X,Popescu I,Botea F,Froněk J,Kroy D,Koch A,Tacke F,Trautwein C,Tolba RH,Hein M,Koek GH,Dejong CHC,Neumann UP,Lurje G

更新日期：2017-10-10 00:00:00

abstract：INTRODUCTION:Early childhood development (ECD) is a critical component for building the foundation of future physical and emotional health and subsequent academic success. The quality of the home environment to promote development is an important factor in ECD. Since large rural-urban disparities in the home environmen...

journal_title：BMJ open

authors： Xu M,Liu A,Zhao C,Fang H,Huang X,Berman S,Guan H

更新日期：2020-10-19 00:00:00

abstract：BACKGROUND:Childhood obesity studies rely on parentally reported anthropometrics. However, the accuracy of such data has not been evaluated for 12-month-old children. Moreover, methods to improve the accuracy of reported data have not been assessed in prior studies. METHODS:A total of 185 children enrolled in a northe...

journal_title：BMJ open

authors： Hazrati S,Hourigan SK,Waller A,Yui Y,Gilchrist N,Huddleston K,Niederhuber J

更新日期：2016-08-04 00:00:00

abstract：OBJECTIVES:To clarify the relationship between social deprivation and age as two factors associated with emergency admissions to hospital. DESIGN:Emergency admissions for 12 months were analysed for patients in the NHS NEW Devon CCG. Social deprivation was measured by the Index of Multiple Deprivation (IMD). Logistic ...

journal_title：BMJ open

authors： Pereira Gray D,Henley W,Chenore T,Sidaway-Lee K,Evans P

更新日期：2017-02-14 00:00:00

abstract：OBJECTIVES:Hospice care (HC) is seen as a comprehensive approach, that enhances quality of end-of-life (EOL) care, for terminally ill patients. Despite its positive aspects, HC enrolment is disproportionate for rural patients, who are less likely to use HC in comparison to their urban counterparts. The purpose of this ...

journal_title：BMJ open

authors： Ko E,Fuentes D,Singh-Carlson S,Nedjat-Haiem F

更新日期：2020-07-01 00:00:00

abstract：INTRODUCTION:Healthcare systems around the world are looking for solutions to the growing problem of mental disorders. RECOVER is the synonym for an evidence-based, stepped and cross-sectoral coordinated care service model for mental disorders. RECOVER implements a cross-sectoral network with managed care, comprehensiv...

journal_title：BMJ open

authors： Lambert M,Karow A,Gallinat J,Lüdecke D,Kraft V,Rohenkohl A,Schröter R,Finter C,Siem AK,Tlach L,Werkle N,Bargel S,Ohm G,Hoff M,Peter H,Scherer M,Mews C,Pruskil S,Lüke J,Härter M,Dirmaier J,Schulte-Markwort M,Lö

更新日期：2020-05-04 00:00:00

abstract：OBJECTIVE:To assess the association of socioeconomic deprivation (SED) with survival after stroke in China. DESIGN:A systematic literature review and a new population-based cohort study. SETTING AND PARTICIPANTS:In urban and rural communities in Anhui, China, 2978 residents aged ≥60 years took part in baseline invest...

journal_title：BMJ open

authors： Chen R,Hu Z,Chen RL,Zhang D,Xu L,Wang J,Wei L

更新日期：2015-01-30 00:00:00

abstract：OBJECTIVE:To evaluate the appropriateness of the initial prescribed daily dose of non-vitamin K antagonist oral anticoagulants (NOACs) according to label in patients with non-valvular atrial fibrillation (NVAF) in the UK. DESIGN:Population-based cross-sectional study. SETTING:UK primary care. POPULATION:30 467 patie...

journal_title：BMJ open

authors： García Rodríguez LA,Martín-Pérez M,Vora P,Roberts L,Balabanova Y,Brobert G,Fatoba S,Suzart-Woischnik K,Schaefer B,Ruigomez A

更新日期：2019-09-20 00:00:00

abstract：INTRODUCTION:Trigeminal neuralgia (TN) affects 4 to 28.9/100 000 people worldwide, and antiepileptic drugs such as carbamazepine and oxcarbazepine are the firstline treatment options. However, the efficacy and safety of other antiepileptic drugs remain unclear due to insufficient direct comparisons. OBJECTIVE:To compa...

journal_title：BMJ open

authors： Qin Z,Xie S,Mao Z,Liu Y,Wu J,Furukawa TA,Kwong JSW,Tian J,Liu Z

更新日期：2018-01-21 00:00:00

abstract：INTRODUCTION:Dextro-transposition of the great arteries (d-TGA) is a life-threatening congenital health defect that requires rapid surgery. The most widely used approach is the arterial switch operation (ASO) developed by Jatene in the 1970s. The first set of children who received this intervention are now adults. The ...

journal_title：BMJ open

authors： Mbuagbaw L,Forlemu-Kamwa D,Chu A,Thabane L,Dillenberg R

更新日期：2014-06-11 00:00:00

abstract：INTRODUCTION:Recurrent urinary tract infections (RUTIs) have a significant negative impact on quality of life and healthcare costs. To date, daily prophylactic antibiotics are the only treatment which have been shown to help prevent RUTIs. D-mannose is a type of sugar which is believed to inhibit bacterial adherence to...

journal_title：BMJ open

authors： Franssen M,Cook J,Robinson J,Williams N,Glogowska M,Yang Y,Allen J,Butler CC,Thomas N,Hay A,Moore M,Hayward G

更新日期：2021-01-13 00:00:00

abstract：INTRODUCTION:Persistent postconcussive symptoms (PCSs) is the persistence of somatic, cognitive, physical, psychological and/or behavioural changes lasting more than 1 month following concussion. Persistent concussion impacts the quality of life through impaired cognition, memory and attention affecting school performa...

journal_title：BMJ open

authors： Zemek R,Osmond MH,Barrowman N,Pediatric Emergency Research Canada (PERC) Concussion Team.

更新日期：2013-08-01 00:00:00

abstract：INTRODUCTION:Evidence from animal studies suggest that the rate of ageing may be influenced not only by genetic and lifestyle factors, but also by the prenatal environment. We have previously shown that people who were exposed to famine during early gestation performed worse on a selective attention task, which may be ...

journal_title：BMJ open

authors： de Rooij SR,Roseboom TJ

更新日期：2013-06-20 00:00:00

abstract：OBJECTIVES:In the UK there are approximately 850 000 new fractures seen each year. Rates of non-union of 5-10% of fractures have been suggested, the cost to the National Health Service of treating non-union has been reported to range between £7000 and £79 000 per person yet there are little actual data available. The o...

journal_title：BMJ open

authors： Mills LA,Simpson AH

更新日期：2013-02-08 00:00:00

abstract：OBJECTIVES:Pain is linked to an increased risk of sickness absence (SA); however, the extent to which unmeasured time-invariant differences explain this association is yet unknown. Therefore, we determined the within-individual associations between pain and short-term (in the survey year) and long-term (2 years followi...

journal_title：BMJ open

authors： Hiilamo A,Butterworth P,Shiri R,Ropponen A,Pietiläinen O,Mänty M,Kouvonen A,Lahelma E,Rahkonen O,Lallukka T

更新日期：2019-03-30 00:00:00

abstract：INTRODUCTION:Emergency admission risk prediction models are increasingly used to identify patients, typically with one or more chronic conditions, for proactive management in primary care to avoid admissions, save costs and improve patient experience. AIM:To identify and review the published evidence on the costs, eff...

journal_title：BMJ open

authors： Kingston MR,Evans BA,Nelson K,Hutchings H,Russell I,Snooks H

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVES:To explore gender disparities in infant routine preventive care across maternal countries of birth (MCOB) and by mother tongue among infants of Indian-born mothers. SETTING:Retrospective population-based administrative cohort in Ontario, Canada (births between 2002 and 2014). PARTICIPANTS:350 366 (inclusiv...

journal_title：BMJ open

authors： Pulver A,Guttmann A,Ray JG,O'Campo PJ,Urquia ML

更新日期：2020-07-31 00:00:00

abstract：INTRODUCTION:So-Cheong-Ryong-Tang (SCRT) is a herbal medicine widely used in traditional medicine for treating allergic rhinitis (AR). In animal studies, SCRT has suppressed the progression of AR. The main purpose of this study is to assess the efficacy and safety of the SCRT for the treatment of perennial allergic rhi...

journal_title：BMJ open

authors： Kim MH,Ko Y,Ahn JH,Yun Y,Yun MN,Ko SG,Choi I

更新日期：2017-09-27 00:00:00

abstract：OBJECTIVE:To identify the main areas of uncertainty and subsequent research priorities to inform the ongoing debate around assisted dying. DESIGN:Two-round electronic modified Delphi consultation with experts and interested bodies. SETTING AND PARTICIPANTS:110 groups and individuals interested in the subject of end-o...

journal_title：BMJ open

authors： Rodgers M,Booth A,Norman G,Sowden A

更新日期：2016-06-07 00:00:00

abstract：OBJECTIVES:Development of medical test guidelines differs from intervention guideline development. These differences can pose unique challenges in building evidence-based recommendations to guide clinical practice. The aim of our study was to better understand these challenges, explore reasons behind them and identify ...

journal_title：BMJ open

authors： Gopalakrishna G,Leeflang MM,Davenport C,Sanabria AJ,Alonso-Coello P,McCaffery K,Bossuyt P,Langendam MW

更新日期：2016-09-16 00:00:00

abstract：INTRODUCTION:Severe behavioural problems (SBPs) are a common contributor to morbidity and reduced quality of life in children with intellectual disability (ID). Current medication treatment for SBP is associated with a high risk of side effects. Innovative and safe interventions are urgently needed. Anecdotal reports a...

journal_title：BMJ open

authors： Efron D,Taylor K,Payne JM,Freeman JL,Cranswick N,Mulraney M,Prakash C,Lee KJ,Williams K

更新日期：2020-03-08 00:00:00

abstract：INTRODUCTION:Exposure to secondhand smoke (SHS) increases children's risk of acquiring chest and ear infections, tuberculosis, meningitis and asthma. Smoking bans in public places (where implemented) have significantly reduced adults' exposure to SHS. However, for children, homes remain the most likely place for them t...

journal_title：BMJ open

authors： Siddiqi K,Huque R,Jackson C,Parrott S,Dogar O,Shah S,Thomson H,Sheikh A

更新日期：2015-08-25 00:00:00