Group-based intervention to improve developmental status among children age 6-18 months in rural Shanxi province, China: a study protocol for a cluster randomised controlled trial.

Abstract:

INTRODUCTION:Early childhood development (ECD) is a critical component for building the foundation of future physical and emotional health and subsequent academic success. The quality of the home environment to promote development is an important factor in ECD. Since large rural-urban disparities in the home environment exist in China, there is a critical need to develop and evaluate interventions to promote ECD in rural areas. Individual center-based or home-based interventions dominate the current ECD programmes in rural China. However, group-based interventions offer potential advantages in terms of both effectiveness and cost. Thus, we aim to: (1) evaluate the effectiveness of an integrated group-based intervention, the Care Group Intervention, in enhancing ECD among children age 6-18 months and (2) conduct a cost-effectiveness analysis. METHODS AND ANALYSIS:The Care Group Intervention uses a cluster (by township) randomised controlled trial conducted in Fenxi county, Shanxi province, China, from July 2019, for 1 year. The intervention focuses on five key components of nurturing care including good health, adequate nutrition, responsive caregiving, security and safety, and opportunities for early learning. The intervention comprises small groups of 3-10 children within a certain age range and their primary caregivers that are led by well-trained local facilitators. Outcomes includes infants' developmental quotient (Bayley Scales of Infant Development III, Ages & Stages Questionnaire: Social-Emotional, second edition); anaemia (HemoCue Hb 301+); nurturing environment (Infant/Toddler Home Observation for Measurement of the Environment), parent-child interaction (Teaching Scale) and caregiver depression (Center for Epidemiological Studies Depression). Cost data are collected throughout the entire study to carry out a cost-effectiveness analysis. ETHICS AND DISSEMINATION:This study was approved by the Ethical Committee of Capital Institute of Pediatrics, Beijing, China on 10 July 2018 (SHERLL2018014). Findings and results from this project will be disseminated via publications and presentations. TRIAL REGISTRATION NUMBER:Chinese Clinical Trials Registry: ChiCTR1900022894. Registered on 30 April 2019.

journal_name

BMJ Open

journal_title

BMJ open

authors

Xu M,Liu A,Zhao C,Fang H,Huang X,Berman S,Guan H

doi

10.1136/bmjopen-2020-037156

subject

Has Abstract

pub_date

2020-10-19 00:00:00

pages

e037156

issue

10

issn

2044-6055

pii

bmjopen-2020-037156

journal_volume

10

pub_type

杂志文章

相关文献

BMJ Open文献大全
  • Use of the SONET score to evaluate Urgent Care Center overcrowding: a prospective pilot study.

    abstract:OBJECTIVES:To derive a tool to determine Urgent Care Center (UCC) crowding and investigate the association between different levels of UCC overcrowding and negative patient care outcomes. DESIGN:Prospective pilot study. SETTING:Single centre study in the USA. PARTICIPANTS:3565 patients who registered at UCC during t...

    journal_title:BMJ open

    pub_type: 杂志文章

    doi:10.1136/bmjopen-2014-006860

    authors: Wang H,Robinson RD,Cowden CD,Gorman VA,Cook CD,Gicheru EK,Schrader CD,Jayswal RD,Zenarosa NR

    更新日期:2015-04-14 00:00:00

  • Quantifying the incidence and burden of herpes zoster in New Zealand general practice: a retrospective cohort study using a natural language processing software inference algorithm.

    abstract:OBJECTIVE:To investigate the incidence of primary care presentations for herpes zoster (zoster) in a representative New Zealand population and to evaluate the utilisation of primary healthcare services following zoster diagnosis. DESIGN:A cross-sectional retrospective cohort study used a natural language processing so...

    journal_title:BMJ open

    pub_type: 杂志文章

    doi:10.1136/bmjopen-2017-021241

    authors: Turner NM,MacRae J,Nowlan ML,McBain L,Stubbe MH,Dowell A

    更新日期:2018-05-31 00:00:00

  • Automatic brain lesion segmentation on standard magnetic resonance images: a scoping review.

    abstract:OBJECTIVES:Medical image analysis practices face challenges that can potentially be addressed with algorithm-based segmentation tools. In this study, we map the field of automatic MR brain lesion segmentation to understand the clinical applicability of prevalent methods and study designs, as well as challenges and limi...

    journal_title:BMJ open

    pub_type: 杂志文章

    doi:10.1136/bmjopen-2020-042660

    authors: Gryska E,Schneiderman J,Björkman-Burtscher I,Heckemann RA

    更新日期:2021-01-29 00:00:00

  • Family history of non-communicable diseases and associations with weight and movement behaviours in Australian school-aged children: a prospective study.

    abstract:OBJECTIVE:To assess differences in weight status and movement behaviour guideline compliance among children aged 5-12 years with and without a family history of non-communicable diseases (NCDs). DESIGN:Prospective. SETTING AND PARTICIPANTS:Women born between 1973 and 1978 were recruited to the Australian Longitudinal...

    journal_title:BMJ open

    pub_type: 杂志文章

    doi:10.1136/bmjopen-2020-038789

    authors: Downing KL,Hesketh KD,Timperio A,Salmon J,Moss K,Mishra G

    更新日期:2020-11-03 00:00:00

  • Early PARacetamol (EPAR) trial: a study protocol for a randomised controlled trial of early paracetamol to promote closure of the ductus arteriosus in preterm infants.

    abstract:INTRODUCTION:The optimal management of patent ductus arteriosus (PDA) remains contentious. The medications used to treat PDA are often non-steroidal anti-inflammatory drugs, which are associated with a number of unwanted adverse effects. Paracetamol is a medication with an excellent safety profile in infants and has be...

    journal_title:BMJ open

    pub_type: 杂志文章

    doi:10.1136/bmjopen-2019-031428

    authors: Schindler T,Smyth J,Bolisetty S,Michalowski J,Lui K

    更新日期:2019-10-30 00:00:00

  • Prescribing practice of pregabalin/gabapentin in pain therapy: an evaluation of German claim data.

    abstract:OBJECTIVES:To analyse the prevalence and incidence of pregabalin and gabapentin (P/G) prescriptions, typical therapeutic uses of P/G with special attention to pain-related diagnoses and discontinuation rates. DESIGN:Secondary data analysis. SETTING:Primary and secondary care in Germany. PARTICIPANTS:Four million pat...

    journal_title:BMJ open

    pub_type: 杂志文章

    doi:10.1136/bmjopen-2018-021535

    authors: Viniol A,Ploner T,Hickstein L,Haasenritter J,Klein KM,Walker J,Donner-Banzhoff N,Becker A

    更新日期:2019-03-30 00:00:00

  • Development of an optimised 1:1 physiotherapy intervention post first-time lumbar discectomy: a mixed-methods study.

    abstract:OBJECTIVES:To develop an optimised 1:1 physiotherapy intervention that reflects best practice, with flexibility to tailor management to individual patients, thereby ensuring patient-centred practice. DESIGN:Mixed-methods combining evidence synthesis, expert review and focus groups. SETTING:Secondary care involving 5 ...

    journal_title:BMJ open

    pub_type: 杂志文章,多中心研究

    doi:10.1136/bmjopen-2015-009409

    authors: Rushton A,White L,Heap A,Calvert M,Heneghan N,Goodwin P

    更新日期:2016-02-25 00:00:00

  • Does childhood adversity account for poorer mental and physical health in second-generation Irish people living in Britain? Birth cohort study from Britain (NCDS).

    abstract:OBJECTIVES:Worldwide, the Irish diaspora experience elevated mortality and morbidity across generations, not accounted for through socioeconomic position. The main objective of the present study was to assess if childhood disadvantage accounts for poorer mental and physical health in adulthood, in second-generation Iri...

    journal_title:BMJ open

    pub_type: 杂志文章

    doi:10.1136/bmjopen-2012-001335

    authors: Das-Munshi J,Clark C,Dewey ME,Leavey G,Stansfeld SA,Prince MJ

    更新日期:2013-03-01 00:00:00

  • Spatial epidemiology of gestational age and birth weight in Switzerland: census-based linkage study.

    abstract:BACKGROUND:Gestational age and birth weight are strong predictors of infant morbidity and mortality. Understanding spatial variation can inform policies to reduce health inequalities. We examined small-area variation in gestational age and birth weight in Switzerland. METHODS:All singleton live births recorded in the ...

    journal_title:BMJ open

    pub_type: 杂志文章

    doi:10.1136/bmjopen-2018-027834

    authors: Skrivankova V,Zwahlen M,Adams M,Low N,Kuehni C,Egger M

    更新日期:2019-10-30 00:00:00

  • What are the prevalence and predictors of psychosocial healthcare among patients with heart disease? A nationwide population-based cohort study.

    abstract:OBJECTIVES:Psychosocial healthcare is recommended, but little is known about how patients perceive the level of care and whether subgroups of patients experience less psychosocial healthcare than others. We examined the prevalence of patient-reported psychosocial healthcare and factors predicting patient-reported lack ...

    journal_title:BMJ open

    pub_type: 杂志文章

    doi:10.1136/bmjopen-2020-037691

    authors: Zinckernagel L,Ersbøll AK,Holmberg T,Pedersen SS,Timm HU,Zwisler AD

    更新日期:2020-10-10 00:00:00

  • Oxidative stress and DNA damage in a long-term hexavalent chromium-exposed population in North China: a cross-sectional study.

    abstract:OBJECTIVE:The International Agency for Research on Cancer classifies hexavalent chromium (Cr(VI)) as a human carcinogen. As reported, cancer mortality was higher in Cr(VI)-contaminated areas. Scientists have recommended studying its health impact on people living in contaminated areas. This study aims to evaluate the h...

    journal_title:BMJ open

    pub_type: 杂志文章

    doi:10.1136/bmjopen-2017-021470

    authors: Xu J,Zhao M,Pei L,Zhang R,Liu X,Wei L,Yang M,Xu Q

    更新日期:2018-06-27 00:00:00

  • OPtimising Treatment for MIld Systolic hypertension in the Elderly (OPTiMISE): protocol for a randomised controlled non-inferiority trial.

    abstract:INTRODUCTION:Recent evidence suggests that larger blood pressure reductions and multiple antihypertensive drugs may be harmful in older people, particularly frail individuals with polypharmacy and multimorbidity. However, there is a lack of evidence to support deprescribing of antihypertensives, which limits the practi...

    journal_title:BMJ open

    pub_type: 杂志文章,随机对照试验

    doi:10.1136/bmjopen-2018-022930

    authors: Sheppard JP,Burt J,Lown M,Temple E,Benson J,Ford GA,Heneghan C,Hobbs FDR,Jowett S,Little P,Mant J,Mollison J,Nickless A,Ogburn E,Payne R,Williams M,Yu LM,McManus RJ

    更新日期:2018-10-04 00:00:00

  • Access to medicines in Latin America and the Caribbean (LAC): a scoping study.

    abstract:OBJECTIVE:To assess scientific publication and map research gaps on access to medicines (ATM) in Latin American and the Caribbean low-income and middle-income countries (LMIC). DESIGN:Scoping review. Two independent reviewers assessed studies for inclusion and extracted data from each study. INFORMATION SOURCES:Searc...

    journal_title:BMJ open

    pub_type: 杂志文章

    doi:10.1136/bmjopen-2012-002224

    authors: Emmerick IC,Oliveira MA,Luiza VL,Azeredo TB,Bigdeli M

    更新日期:2013-05-03 00:00:00

  • Triple-arm trial of pH (Tri-pH) effect on live birth after ICSI in Egyptian IVF facilities: protocol of a randomised controlled trial.

    abstract:INTRODUCTION:One potential stressor that can affect preimplantation and postimplantation embryonic growth after in vitro fertilisation (IVF) is the pH of the human embryo culture medium, but no evidence exists to indicate which pH level is optimal for IVF. Based on anecdotal evidence or mouse models, culture media manu...

    journal_title:BMJ open

    pub_type: 杂志文章

    doi:10.1136/bmjopen-2019-034194

    authors: Fawzy M,Emad M,Wilkinson J,Mansour R,Mahran A,Fetih A,Abdelrahman M,AbdelGhafar H

    更新日期:2020-02-04 00:00:00

  • Factors that affect the uptake of community-based health insurance in low-income and middle-income countries: a systematic protocol.

    abstract:INTRODUCTION:Many people residing in low-income and middle-income countries (LMICs) are regularly exposed to catastrophic healthcare expenditure. It is therefore pertinent that LMICs should finance their health systems in ways that ensure that their citizens can use needed healthcare services and are protected from pot...

    journal_title:BMJ open

    pub_type: 杂志文章

    doi:10.1136/bmjopen-2013-004167

    authors: Adebayo EF,Ataguba JE,Uthman OA,Okwundu CI,Lamont KT,Wiysonge CS

    更新日期:2014-02-14 00:00:00

  • Discrete choice experiment to evaluate preferences of patients with cystic fibrosis among alternative treatment-related health outcomes: a protocol.

    abstract:INTRODUCTION:Clinical decision-making is a complex process. Patient preference information regarding desirable health states should inform treatment and is critical to agreeing on goals of therapy. Cystic fibrosis (CF) is a common, inheritable multisystem disorder for which the major manifestation is progressive, chron...

    journal_title:BMJ open

    pub_type: 杂志文章

    doi:10.1136/bmjopen-2019-030348

    authors: McLeod C,Norman R,Schultz A,Mascaro S,Webb S,Snelling T

    更新日期:2019-08-18 00:00:00

  • Protocol for intraoperative assessment of the human cerebrovascular glycocalyx.

    abstract:INTRODUCTION:Adequate functioning of the blood-brain barrier (BBB) is important for brain homoeostasis and normal neuronal function. Disruption of the BBB has been described in several neurological diseases. Recent reports suggest that an increased permeability of the BBB also contributes to increased seizure susceptib...

    journal_title:BMJ open

    pub_type: 杂志文章,多中心研究

    doi:10.1136/bmjopen-2016-013954

    authors: Haeren RH,Vink H,Staals J,van Zandvoort MA,Dings J,van Overbeeke JJ,Hoogland G,Rijkers K,Schijns OE

    更新日期:2017-01-05 00:00:00

  • Moderation of alcohol consumption as a recommendation in European hypertension management guidelines: a survey on awareness, screening and implementation among European physicians.

    abstract:OBJECTIVES:Moderation of alcohol consumption is included as a class I, level of evidence A recommendation in the current European guidelines for the management of hypertension. We investigated its awareness and self-reported implementation among European physicians across different specialties and workplaces. DESIGN A...

    journal_title:BMJ open

    pub_type: 杂志文章

    doi:10.1136/bmjopen-2018-022026

    authors: Zaidi Touis L,Bolbrinker J,Riemer TG,Kreutz R

    更新日期:2018-10-21 00:00:00

  • Activities to support the implementation of complex interventions as part of routine care: a review of the quality of reporting in cluster randomised controlled trials.

    abstract:OBJECTIVE:To review a sample of cluster randomised controlled trials and explore the quality of reporting of (1) enabling or support activities provided to the staff during the trial, (2) strategies used to monitor fidelity throughout the trial and (3) the extent to which the intervention being tested was delivered as ...

    journal_title:BMJ open

    pub_type: 杂志文章,评审

    doi:10.1136/bmjopen-2015-008251

    authors: McMahon NE,Holland EJ,Miller C,Patel K,Connell LA

    更新日期:2015-10-09 00:00:00

  • Sources of information used by patients prior to elective surgery: a scoping review.

    abstract:OBJECTIVE:To describe the range and nature of available research regarding sources of information that patients access to inform their decisions about elective surgery. DESIGN:Scoping review. DATA SOURCES:Peer-reviewed studies published until February 2019 from the six scientific literature databases were searched an...

    journal_title:BMJ open

    pub_type: 杂志文章,评审

    doi:10.1136/bmjopen-2018-023080

    authors: Atlas A,Milanese S,Grimmer K,Barras S,Stephens JH

    更新日期:2019-08-05 00:00:00

  • How do doctors and nurses manage delirium in intensive care units? A qualitative study using focus groups.

    abstract:OBJECTIVES:The aim of this study was to explore the experiences of doctors and nurses caring for patients with delirium in the intensive care unit (ICU) and to describe the process of delirium management. SETTING:This study was performed in 5 ICUs located within 4 hospitals in Madrid (Spain). PARTICIPANTS:Purposeful ...

    journal_title:BMJ open

    pub_type: 杂志文章

    doi:10.1136/bmjopen-2015-009678

    authors: Palacios-Ceña D,Cachón-Pérez JM,Martínez-Piedrola R,Gueita-Rodriguez J,Perez-de-Heredia M,Fernández-de-las-Peñas C

    更新日期:2016-01-29 00:00:00

  • Role of community health workers in improving cost efficiency in an active case finding tuberculosis programme: an operational research study from rural Bihar, India.

    abstract:OBJECTIVES:Cost-efficient active case finding (ACF) approaches are needed for their large-scale adoption in national tuberculosis (TB) programmes. Our aim was to assess if community health workers' (CHW) knowledge about families' health status can improve the cost efficiency of the ACF programme without adversely affec...

    journal_title:BMJ open

    pub_type: 杂志文章

    doi:10.1136/bmjopen-2019-036625

    authors: Garg T,Bhardwaj M,Deo S

    更新日期:2020-10-01 00:00:00

  • Epidemiology of multimorbidity among people living with HIV in sub-Saharan Africa: a systematic review protocol.

    abstract:INTRODUCTION:Sub-Saharan Africa remains the epicentre of the HIV pandemic, yet enormous knowledge gaps still exist to elicit a comprehensive portrait of multimorbidity and HIV linkage. This study aims to conduct a systematic meta-analysis of peer-reviewed literature to investigate the current status of multimorbidity e...

    journal_title:BMJ open

    pub_type: 杂志文章

    doi:10.1136/bmjopen-2020-036988

    authors: Oladimeji KE,Dzomba A,Adetokunboh O,Zungu L,Yaya S,Goon DT

    更新日期:2020-12-12 00:00:00

  • Mental health informed physical activity for first responders and their support partner: a protocol for a stepped-wedge evaluation of an online, codesigned intervention.

    abstract:BACKGROUND:First responders (police, fire and ambulance officers) are at a significantly increased risk of experiencing poor mental health, including depression and post-traumatic stress disorder. These conditions are associated with high rates of cardiovascular disease, in part due to low levels of physical activity (...

    journal_title:BMJ open

    pub_type: 杂志文章

    doi:10.1136/bmjopen-2019-030668

    authors: McKeon G,Steel Z,Wells R,Newby JM,Hadzi-Pavlovic D,Vancampfort D,Rosenbaum S

    更新日期:2019-09-11 00:00:00

  • Use of dating sites and applications by women and their risk of sexually transmitted infections: a systematic review and meta-analysis protocol.

    abstract:INTRODUCTION:The use of social networks has been increasing worldwide. Mobile websites and applications (apps) allow people to network more quickly and have more partners for sex. This can facilitate risky sexual behaviours, such as having multiple partners and unprotected sex, which can lead to a higher incidence of s...

    journal_title:BMJ open

    pub_type: 杂志文章

    doi:10.1136/bmjopen-2020-038738

    authors: Queiroz JF,Medeiros KS,Sarmento ACA,Monteiro MN,Cobucci RN,Stransky B,Gonçalves AK

    更新日期:2020-11-19 00:00:00

  • Transdisciplinary research for impact: protocol for a realist evaluation of the relationship between transdisciplinary research collaboration and knowledge translation.

    abstract:INTRODUCTION:Transdisciplinary teams are increasingly regarded as integral to conducting effective research. Similarly, knowledge translation is often seen as a solution to improving the relevance and benefits of health research. Yet, whether, how, for whom and under which circumstances transdisciplinary research influ...

    journal_title:BMJ open

    pub_type: 杂志文章

    doi:10.1136/bmjopen-2018-021775

    authors: Archibald MM,Lawless M,Harvey G,Kitson AL

    更新日期:2018-04-07 00:00:00

  • Vitamin D, obesity and leptin in relation to bladder cancer incidence and survival: prospective protocol study.

    abstract:INTRODUCTION:Bladder cancer (BC) (including renal pelvis, ureter and urethra) is one of the most common urogenital cancers and the fourth most frequent cancer in men in the USA. In Norway, the incidence of BC has increased over the last decades. The age-standardised incidence rates per 100 000 for 2011-2015 were 53.7 i...

    journal_title:BMJ open

    pub_type: 杂志文章

    doi:10.1136/bmjopen-2017-019309

    authors: Gislefoss RE,Stenehjem JS,Hektoen HH,Andreassen BK,Langseth H,Axcrona K,Weiderpass E,Mondul A,Robsahm TE

    更新日期:2018-03-30 00:00:00

  • Increasing the uptake of long-acting reversible contraception in general practice: the Australian Contraceptive ChOice pRoject (ACCORd) cluster randomised controlled trial protocol.

    abstract:INTRODUCTION:The increased use of long-acting reversible contraceptives (LARCs), such as intrauterine devices and hormonal implants, has the potential to reduce unintended pregnancy and abortion rates. However, use of LARCs in Australia is very low, despite clinical practice guidance and statements by national and inte...

    journal_title:BMJ open

    pub_type: 杂志文章,随机对照试验

    doi:10.1136/bmjopen-2016-012491

    authors: Mazza D,Black K,Taft A,Lucke J,McGeechan K,Haas M,McKay H,Peipert JF

    更新日期:2016-10-07 00:00:00

  • How do time trends in inhospital mortality compare? A retrospective study of England and Scotland over 17 years using administrative data.

    abstract:OBJECTIVES:To examine the trends in inhospital mortality for England and Scotland over a 17-year period to determine whether and if so to what extent the time trends differ after controlling for differences in the patients treated. DESIGN:Analysis of retrospective administrative hospital data using descriptive aggrega...

    journal_title:BMJ open

    pub_type: 杂志文章,多中心研究

    doi:10.1136/bmjopen-2017-017195

    authors: Aragón MJ,Chalkley M

    更新日期:2018-02-21 00:00:00

  • Adiposity change and mortality in middle-aged to older Chinese: an 8-year follow-up of the Guangzhou Biobank Cohort Study.

    abstract:OBJECTIVE:To examine the associations of change in body mass index (BMI) and waist circumference (WC) over an average of 4 years with subsequent mortality risk in middle-aged to older Chinese. DESIGN:Prospective cohort study based on the Guangzhou Biobank Cohort Study. SETTING:Community-based sample. PARTICIPANTS:17...

    journal_title:BMJ open

    pub_type: 杂志文章

    doi:10.1136/bmjopen-2020-039239

    authors: Huang YY,Jiang CQ,Xu L,Zhang WS,Zhu F,Jin YL,Thomas GN,Cheng KK,Lam TH

    更新日期:2020-12-04 00:00:00