Immunoglobulin M profile of viral and atypical pathogens among children with community acquired lower respiratory tract infections in Luzhou, China.

Abstract:

BACKGROUND:Community-acquired lower respiratory tract infections (CA-LRTIs) are the primary cause of hospitalization among children globally. A better understanding of the role of atypical pathogen infections in native conditions is essential to improve clinical management and preventive measures. The main objective of this study was to detect the presence of 7 respiratory viruses and 2 atypical pathogens among hospitalized infants and children with community-acquired lower respiratory tract infections in Luzhou via an IgM test. METHODS:Overall, 6623 cases of local hospitalized children with 9 pathogen-IgM results from 1st July 2013 to 31st Dec 2016 were included; multidimensional analysis was performed. RESULTS:1) Out of 19,467 hospitalized children with lower respiratory tract infections, 6623 samples were collected, for a submission ratio of 33.96% (6623 /19467). Of the total 6623 serum samples tested, 5784 IgM stains were positive, for a ratio of 87.33% (5784 /6623). Mycoplasma pneumoniae (MP) was the dominant pathogen (2548 /6623, 38.47%), with influenza B (INFB) (1606 /6623, 24.25%), Legionella pneumophila serogroup 1 (LP1) (485 /6623, 7.32%) and parainfluenza 1, 2 and 3(PIVs) (416 /6623, 6.28%) ranking second, third and fourth, respectively. 2) The distribution of various pathogen-IgM by age group was significantly different (χ2 = 455.039, P < 0.05). 3) Some pathogens were found to be associated with a certain age of children and seasons statistically. CONCLUSIONS:The dominant positive IgM in the area was MP, followed by INFB, either of which prefers to infect children between 2 years and 5 years in autumn. The presence of atypical pathogens should not be underestimated clinically as they were common infections in the respiratory tract of children in the hospital.

journal_name

BMC Pediatr

journal_title

BMC pediatrics

authors

Chen A,Song L,Chen Z,Luo X,Jiang Q,Yang Z,Hu L,He J,Zhou L,Yu H

doi

10.1186/s12887-019-1649-6

subject

Has Abstract

pub_date

2019-08-13 00:00:00

pages

280

issue

1

issn

1471-2431

pii

10.1186/s12887-019-1649-6

journal_volume

19

pub_type

杂志文章
  • Bacterial profile and antibacterial susceptibility of otitis media among pediatric patients in Hawassa, Southern Ethiopia: cross-sectional study.

    abstract:BACKGROUND:Otitis Media (OM) is the most common disease of childhood. Twenty thousand people die each year from otitis media. It is an important cause of preventable hearing loss, affects children's intellectual performance and language development. There are very small numbers of studies done in Ethiopia concerning th...

    journal_title:BMC pediatrics

    pub_type: 杂志文章,多中心研究

    doi:10.1186/s12887-019-1781-3

    authors: Tadesse B,Shimelis T,Worku M

    更新日期:2019-11-01 00:00:00

  • Improving the outcome of infants born at

    abstract:BACKGROUND:Early developmental interventions to prevent the high rate of neurodevelopmental problems in very preterm children, including cognitive, motor and behavioral impairments, are urgently needed. These interventions should be multi-faceted and include modules for caregivers given their high rates of mental healt...

    journal_title:BMC pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1186/1471-2431-9-73

    authors: Spittle AJ,Ferretti C,Anderson PJ,Orton J,Eeles A,Bates L,Boyd RN,Inder TE,Doyle LW

    更新日期:2009-12-03 00:00:00

  • Pain, motor function and health-related quality of life in children with cerebral palsy as reported by their physiotherapists.

    abstract:BACKGROUND:Children and adolescents with cerebral palsy suffer from higher levels of pain than their peers without disability. The aim of this study was to explore the impact of pain on health-related quality of life and motor function in individuals with cerebral palsy as reported by health professionals. METHODS:Cro...

    journal_title:BMC pediatrics

    pub_type: 杂志文章

    doi:10.1186/1471-2431-14-192

    authors: Badia M,Riquelme I,Orgaz B,Acevedo R,Longo E,Montoya P

    更新日期:2014-07-27 00:00:00

  • Prevalence of underweight, overweight and obesity among Palestinian school-age children and the associated risk factors: a cross sectional study.

    abstract:BACKGROUND:Childhood obesity is rising in developed and developing countries, while childhood underweight is rising mainly in developing countries. Childhood underweight has been shown to increase a child's risk of rapid weight gain. Overweight and obese children are more likely to become obese adults, which increases ...

    journal_title:BMC pediatrics

    pub_type: 杂志文章

    doi:10.1186/s12887-019-1842-7

    authors: Al-Lahham S,Jaradat N,Altamimi M,Anabtawi O,Irshid A,AlQub M,Dwikat M,Nafaa F,Badran L,Mohareb R,Haji R,Aqqad T,Jayyab S,Ghosh BA,Taher R,Al Zabadi H

    更新日期:2019-12-09 00:00:00

  • Mode of delivery and other risk factors for Escherichia coli infections in very low birth weight infants.

    abstract:BACKGROUND:Infections in newborns remain one of the most significant problems in modern medicine. Escherichia coli is an important cause of neonatal bloodstream and respiratory tract infections and is associated with high mortality. The aim of our study was to investigate the epidemiology of E. coli infection in Polish...

    journal_title:BMC pediatrics

    pub_type: 杂志文章

    doi:10.1186/1471-2431-14-274

    authors: Chmielarczyk A,Wójkowska-Mach J,Romaniszyn D,Adamski P,Helwich E,Lauterbach R,Pobiega M,Borszewska-Kornacka M,Gulczyńska E,Kordek A,Heczko PB

    更新日期:2014-10-18 00:00:00

  • Australian national birthweight percentiles by sex and gestational age for twins, 2001-2010.

    abstract:BACKGROUND:Birthweight remains one of the strongest predictors of perinatal mortality and disability. Birthweight percentiles form a reference that allows the detection of neonates at higher risk of neonatal and postneonatal morbidity. The aim of the study is to present updated national birthweight percentiles by gesta...

    journal_title:BMC pediatrics

    pub_type: 杂志文章

    doi:10.1186/s12887-015-0464-y

    authors: Li Z,Umstad MP,Hilder L,Xu F,Sullivan EA

    更新日期:2015-10-08 00:00:00

  • A systematic review of the psychometric properties of Quality of Life measures for school aged children with cerebral palsy.

    abstract:BACKGROUND:This systematic review aimed to evaluate the psychometric properties and clinical utility of all condition specific outcome measures used to assess quality of life (QOL) in school aged children with cerebral palsy (CP). METHODS:Relevant outcome measures were identified by searching 8 electronic databases, s...

    journal_title:BMC pediatrics

    pub_type: 杂志文章,评审

    doi:10.1186/1471-2431-10-81

    authors: Carlon S,Shields N,Yong K,Gilmore R,Sakzewski L,Boyd R

    更新日期:2010-11-09 00:00:00

  • Parents' reported preference scores for childhood atopic dermatitis disease states.

    abstract:BACKGROUND:We sought to elicit preference weights from parents for health states corresponding to children with various levels of severity of atopic dermatitis. We also evaluated the hypothesis that parents with children who had been diagnosed with atopic dermatitis would assign different preferences to the health stat...

    journal_title:BMC pediatrics

    pub_type: 杂志文章

    doi:10.1186/1471-2431-4-21

    authors: Friedman JY,Reed SD,Weinfurt KP,Kahler KH,Walter EB,Schulman KA

    更新日期:2004-10-18 00:00:00

  • Undernourished children presenting to an urban emergency department of a tertiary hospital in Tanzania: a prospective descriptive study.

    abstract:BACKGROUND:Childhood undernutrition causes significant morbidity and mortality in low- and middle-income countries (LMICs). In Tanzania, the in-hospital prevalence of undernutrition in children under five years of age is approximated to be 30% with a case fatality rate of 8.8%. In Tanzania, the burden of undernourished...

    journal_title:BMC pediatrics

    pub_type: 杂志文章

    doi:10.1186/s12887-019-1706-1

    authors: Bashaka PJ,Sawe HR,Mwafongo V,Mfinanga JA,Runyon MS,Murray BL

    更新日期:2019-09-11 00:00:00

  • Methemoglobin and nitric oxide therapy in Ugandan children hospitalized for febrile illness: results from a prospective cohort study and randomized double-blind placebo-controlled trial.

    abstract:BACKGROUND:Exposure of red blood cells to oxidants increases production of methemoglobin (MHb) resulting in impaired oxygen delivery to tissues. There are no reliable estimates of methemoglobinemia in low resource clinical settings. Our objectives were to: i) evaluate risk factors for methemoglobinemia in Ugandan child...

    journal_title:BMC pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1186/s12887-016-0719-2

    authors: Conroy AL,Hawkes M,Hayford K,Hermann L,McDonald CR,Sharma S,Namasopo S,Opoka RO,John CC,Liles WC,Miller C,Kain KC

    更新日期:2016-11-04 00:00:00

  • Passive smoking as a risk factor of anemia in young children aged 0-35 months in Jordan.

    abstract:BACKGROUND:Passive smoking unfavorably affects pregnancy, child birth and child health. Passive smoking associates with still-birth, premature birth as well as acute respiratory infection, asthma, disorder in red blood cell metabolism in children. This study examined the effects of passive smoking on anemia in young ch...

    journal_title:BMC pediatrics

    pub_type: 杂志文章

    doi:10.1186/1471-2431-7-16

    authors: Hong R,Betancourt JA,Ruiz-Beltran M

    更新日期:2007-04-10 00:00:00

  • Selected hematologic and biochemical measurements in African HIV-infected and uninfected pregnant women and their infants: the HIV Prevention Trials Network 024 protocol.

    abstract:BACKGROUND:Reference values for hematological and biochemical assays in pregnant women and in newborn infants are based primarily on Caucasian populations. Normative data are limited for populations in sub-Saharan Africa, especially comparing women with and without HIV infection, and comparing infants with and without ...

    journal_title:BMC pediatrics

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1186/1471-2431-9-49

    authors: Mwinga K,Vermund SH,Chen YQ,Mwatha A,Read JS,Urassa W,Carpenetti N,Valentine M,Goldenberg RL

    更新日期:2009-08-07 00:00:00

  • Correction to: Decision-making at the limit of viability: differing perceptions and opinions between neonatal physicians and nurses.

    abstract::After publication of our article [1] it was brought to our attention that we did not have permission to reproduce the questionnaire in Additional File 1. ...

    journal_title:BMC pediatrics

    pub_type: 已发布勘误

    doi:10.1186/s12887-019-1890-z

    authors: Bucher HU,Klein SD,Hendriks MJ,Baumann-Hölzle R,Berger TM,Streuli JC,Fauchère JC,Swiss Neonatal End-of-Life Study Group.

    更新日期:2020-01-31 00:00:00

  • Early Check: translational science at the intersection of public health and newborn screening.

    abstract:BACKGROUND:Newborn screening (NBS) occupies a unique space at the intersection of translational science and public health. As the only truly population-based public health program in the United States, NBS offers the promise of making the successes of translational medicine available to every infant with a rare disorde...

    journal_title:BMC pediatrics

    pub_type: 杂志文章

    doi:10.1186/s12887-019-1606-4

    authors: Bailey DB Jr,Gehtland LM,Lewis MA,Peay H,Raspa M,Shone SM,Taylor JL,Wheeler AC,Cotten M,King NMP,Powell CM,Biesecker B,Bishop CE,Boyea BL,Duparc M,Harper BA,Kemper AR,Lee SN,Moultrie R,Okoniewski KC,Paquin RS,Pe

    更新日期:2019-07-17 00:00:00

  • Randomized, controlled trial comparing laryngeal mask versus endotracheal intubation during neonatal resuscitation---a secondary publication.

    abstract:BACKGROUND:This study aimed to study the feasibility, efficacy and safety of using laryngeal mask (LM) ventilation compared with endotracheal intubation (ETI) during neonatal resuscitation. METHODS:Neonates with a heart rate below 60 beats per minute despite 30 s of face mask ventilation were assigned quasi-randomly (...

    journal_title:BMC pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1186/s12887-016-0553-6

    authors: Yang C,Zhu X,Lin W,Zhang Q,Su J,Lin B,Ye H,Yu R

    更新日期:2016-01-25 00:00:00

  • Brain biomarkers and pre-injury cognition are associated with long-term cognitive outcome in children with traumatic brain injury.

    abstract:BACKGROUND:Children with traumatic brain injury (TBI) are frequently at risk of long-term impairments of attention and executive functioning but these problems are difficult to predict. Although deficits have been reported to vary with injury severity, age at injury and sex, prognostication of outcome remains imperfect...

    journal_title:BMC pediatrics

    pub_type: 杂志文章,多中心研究

    doi:10.1186/s12887-017-0925-6

    authors: Wilkinson AA,Dennis M,Simic N,Taylor MJ,Morgan BR,Frndova H,Choong K,Campbell C,Fraser D,Anderson V,Guerguerian AM,Schachar R,Hutchison J,Canadian Critical Care Trials Group (CCCTG).,Canadian Critical Care Translational Biolo

    更新日期:2017-07-24 00:00:00

  • Antenatal and postnatal diagnoses of visible congenital malformations in a sub-Saharan African setting: a prospective multicenter cohort study.

    abstract:BACKGROUND:Visible congenital malformations (VCMs) are one of the principal causes of disability in the world. Prenatal diagnosis is a paramount mandatory integral part of the follow up of pregnancies with VCM of the foetus in high-income setting. We aimed to determine the incidence of prenatal diagnosis of VCMs in a l...

    journal_title:BMC pediatrics

    pub_type: 杂志文章,多中心研究

    doi:10.1186/s12887-019-1831-x

    authors: Kamla I,Kamgaing N,Billong S,Tochie JN,Tolefac P,de Paul Djientcheu V

    更新日期:2019-11-25 00:00:00

  • Cross-cultural adaptation of the Participation and Environment Measure for Children and Youth (PEM-CY) into German: a qualitative study in three countries.

    abstract:BACKGROUND:Concepts such as participation and environment may differ across cultures. Consequently, to use a measure like the Participation and Environment Measure for Children and Youth (PEM-CY) in other than the original English-speaking contexts, cultural adaptation needs to be assured. The aim of this study was to ...

    journal_title:BMC pediatrics

    pub_type: 杂志文章

    doi:10.1186/s12887-020-02343-y

    authors: Krieger B,Schulze C,Boyd J,Amann R,Piškur B,Beurskens A,Teplicky R,Moser A

    更新日期:2020-10-24 00:00:00

  • Health, schooling, needs, perspectives and aspirations of HIV infected and affected children in Botswana: a cross-sectional survey.

    abstract:BACKGROUND:Antiretroviral treatment means many HIV infected children are surviving with a highly stigmatised condition. There is a paucity of data to inform policies for this growing cohort. Hence we carried out a study on the health, schooling, needs, aspirations, perspectives and knowledge of HIV infected and affecte...

    journal_title:BMC pediatrics

    pub_type: 杂志文章

    doi:10.1186/s12887-016-0643-5

    authors: Anabwani G,Karugaba G,Gabaitiri L

    更新日期:2016-07-22 00:00:00

  • Feeding and smoking habits as cumulative risk factors for early childhood caries in toddlers, after adjustment for several behavioral determinants: a retrospective study.

    abstract:BACKGROUND:Several maternal health determinants during the first period of life of the child, as feeding practice, smoking habit and socio-economic level, are involved in early childhood health problems, as caries development. The potential associations among early childhood caries, feeding practices, maternal and envi...

    journal_title:BMC pediatrics

    pub_type: 杂志文章

    doi:10.1186/1471-2431-14-45

    authors: Majorana A,Cagetti MG,Bardellini E,Amadori F,Conti G,Strohmenger L,Campus G

    更新日期:2014-02-15 00:00:00

  • Low serum vitamin-D status is associated with high prevalence and early onset of type-1 diabetes mellitus in Kuwaiti children.

    abstract:BACKGROUND:Type 1 diabetes mellitus (T1DM) is highly prevalent in Kuwait with incidence of around 40.1/100,000 individuals. Evidence indicate that vitamin D plays an important role in modulating the immune system and could thus impact the onset and high prevalence of T1DM. We report serum vitamin D levels in Kuwaiti ch...

    journal_title:BMC pediatrics

    pub_type: 杂志文章

    doi:10.1186/s12887-016-0629-3

    authors: Rasoul MA,Al-Mahdi M,Al-Kandari H,Dhaunsi GS,Haider MZ

    更新日期:2016-07-16 00:00:00

  • The Linked CENTURY Study: linking three decades of clinical and public health data to examine disparities in childhood obesity.

    abstract:BACKGROUND:Despite the need to identify the causes of disparities in childhood obesity, the existing epidemiologic studies of early life risk factors have several limitations. We report on the construction of the Linked CENTURY database, incorporating CENTURY (Collecting Electronic Nutrition Trajectory Data Using Recor...

    journal_title:BMC pediatrics

    pub_type: 杂志文章

    doi:10.1186/s12887-016-0567-0

    authors: Hawkins SS,Gillman MW,Rifas-Shiman SL,Kleinman KP,Mariotti M,Taveras EM

    更新日期:2016-03-09 00:00:00

  • Structured on-the-job training to improve retention of newborn resuscitation skills: a national cohort Helping Babies Breathe study in Tanzania.

    abstract:BACKGROUND:Newborn resuscitation is a life-saving intervention for birth asphyxia, a leading cause of neonatal mortality. Improving provider newborn resuscitation skills is critical for delivering quality care, but the retention of these skills has been a challenge. Tanzania implemented a national newborn resuscitation...

    journal_title:BMC pediatrics

    pub_type: 杂志文章

    doi:10.1186/s12887-019-1419-5

    authors: Drake M,Bishanga DR,Temu A,Njozi M,Thomas E,Mponzi V,Arlington L,Msemo G,Azayo M,Kairuki A,Meda AR,Isangula KG,Nelson BD

    更新日期:2019-02-07 00:00:00

  • Dynamics of toxigenic Clostridium perfringens colonisation in a cohort of prematurely born neonatal infants.

    abstract:BACKGROUND:Clostridium perfringens forms part of the human gut microbiota and has been associated with life-threatening necrotising enterocolitis (NEC) in premature infants. Whether specific toxigenic strains are responsible is unknown, as is the extent of diversity of strains in healthy premature babies. We investigat...

    journal_title:BMC pediatrics

    pub_type: 杂志文章

    doi:10.1186/s12887-020-1976-7

    authors: Shaw AG,Cornwell E,Sim K,Thrower H,Scott H,Brown JCS,Dixon RA,Kroll JS

    更新日期:2020-02-18 00:00:00

  • Reporting and methodologic quality of Cochrane Neonatal review group systematic reviews.

    abstract:BACKGROUND:The Cochrane Neonatal Review Group (CNRG) has achieved a lot with limited resources in producing high quality systematic reviews to assist clinicians in evidence-based decision-making. A formal assessment of published CNRG systematic reviews has not been undertaken; we sought to provide a comprehensive asses...

    journal_title:BMC pediatrics

    pub_type: 杂志文章

    doi:10.1186/1471-2431-9-38

    authors: Al Faleh K,Al-Omran M

    更新日期:2009-06-17 00:00:00

  • Dietary intake in 6-year-old children from southern Poland: part 1--energy and macronutrient intakes.

    abstract:BACKGROUND:The studies on dietary intake in Polish children are sparse and the information about dietary intake in 6-year-olds in Europe is limited. The published studies on dietary intake in children rarely provide information on the intake of animal protein, plant protein and water. The purpose of the study was to an...

    journal_title:BMC pediatrics

    pub_type: 杂志文章

    doi:10.1186/1471-2431-14-197

    authors: Merkiel S

    更新日期:2014-08-03 00:00:00

  • Differing views regarding diet and physical activity: adolescents versus parents' perspectives.

    abstract:BACKGROUND:Today, approximately one in five United States adolescents age 12 to 19 years is obese and just over a third are either overweight or obese. This study examines how parents and peers influence diet and physical activity behaviors of older adolescents (14-18 years) with overweight or obesity to inform weight ...

    journal_title:BMC pediatrics

    pub_type: 杂志文章

    doi:10.1186/s12887-020-02038-4

    authors: Azar KMJ,Halley M,Lv N,Wulfovich S,Gillespie K,Liang L,Goldman Rosas L

    更新日期:2020-03-27 00:00:00

  • Thresholds for oximetry alarms and target range in the NICU: an observational assessment based on likely oxygen tension and maturity.

    abstract:BACKGROUND:Continuous monitoring of SpO2 in the neonatal ICU is the standard of care. Changes in SpO2 exposure have been shown to markedly impact outcome, but limiting extreme episodes is an arduous task. Much more complicated than setting alarm policy, it is fraught with balancing alarm fatigue and compliance. Informa...

    journal_title:BMC pediatrics

    pub_type: 杂志文章

    doi:10.1186/s12887-020-02225-3

    authors: Bachman TE,Iyer NP,Newth CJL,Ross PA,Khemani RG

    更新日期:2020-06-27 00:00:00

  • A program to respond to otitis media in remote Australian Aboriginal communities: a qualitative investigation of parent perspectives.

    abstract:BACKGROUND:Indigenous infants and children in Australia, especially in remote communities, experience early and chronic otitis media (OM) which is difficult to treat and has lifelong impacts in health and education. The LiTTLe Program (Learning to Talk, Talking to Learn) aimed to increase infants' access to spoken lang...

    journal_title:BMC pediatrics

    pub_type: 杂志文章

    doi:10.1186/s12887-018-1081-3

    authors: Jones C,Sharma M,Harkus S,McMahon C,Taumoepeau M,Demuth K,Mattock K,Rosas L,Wing R,Pawar S,Hampshire A

    更新日期:2018-03-06 00:00:00

  • End-user perspectives to inform policy and program decisions: a qualitative and quantitative content analysis of lifestyle treatment recommendations by adolescents with obesity.

    abstract:BACKGROUND:Lifestyle modifications represent the first line of treatment in obesity management; however, many adolescents with obesity do not meet lifestyle recommendations. Given that adolescents are rarely consulted during health policy development and in the design of lifestyle interventions, their first-hand experi...

    journal_title:BMC pediatrics

    pub_type: 杂志文章

    doi:10.1186/s12887-019-1749-3

    authors: Kebbe M,Perez A,Buchholz A,McHugh TF,Scott SD,Richard C,Dyson MP,Ball GDC

    更新日期:2019-11-08 00:00:00