Abstract:
BACKGROUND:Comprehensive data are needed to evaluate the burden of low birthweight. Analysis of routine data on health-care utilization during early childhood were used to test the hypothesis that infants with low birthweight have (i) increased inpatient health-care utilization, (ii) higher hospital costs and (iii) different morbidity pattern in early childhood when compared with normal birthweight infants. METHODS:Children born between 2007 and 2013 that were insured at birth with the statutory health insurance AOK PLUS were included (N = 118,166, equaling 49% of the Saxon newborns) and classified into very low (< 1500 g, VLBW), low (1500-2499 g, LBW) birthweight and reference group (> 2500 g). Outcomes were: inpatient health-care utilization quantified by number and length of hospital stays; costs of hospitalizations including medication; reasons of hospitalizations for each year of life (YOL). RESULTS:72, 38 and 22% of VLBW-, LBW- and reference group were hospitalized after perinatal period within the first YOL with a more than 5-fold increased risk in VLBW to be hospitalized for hemangioma, convulsions, hydrocephalus, hernia and respiratory problems. Median (IQR) cumulative cost of inpatient care during the first four YOLs was 2953 (1213-7885), 1331 (0-3451) and 0 (0-2062) Euro for respective groups. Inpatient early childhood health-care utilization (after first YOL) was higher in VLBW compared to healthy, normal birth weight infants (RR 3.92 [95%-CI 3.63, 4.23]), residents of rural areas (RR 1.37 [95%-CI 1.35, 1.40]) and in boys (RR 1.31 [95%-CI 1.29, 1.33]). CONCLUSION:This large population-based birth-cohort study indicates a high clinical and economic burden of low birthweight which is not restricted to the first year of life.
journal_name
BMC Pediatrjournal_title
BMC pediatricsauthors
Rüdiger M,Heinrich L,Arnold K,Druschke D,Reichert J,Schmitt Jdoi
10.1186/s12887-019-1424-8subject
Has Abstractpub_date
2019-03-01 00:00:00pages
69issue
1issn
1471-2431pii
10.1186/s12887-019-1424-8journal_volume
19pub_type
杂志文章相关文献
BMC Pediatrics文献大全abstract:BACKGROUND:To explore the relationship between the pathological changes of the colon, terminal ileum, lung, liver and kidney, and the changes of Bax, PCNA and PAF in a rat model of NEC. METHODS:One hundred and forty neonatal SD rats were randomly divided into NEC group and control group (70 in each group). NEC group w...
journal_title:BMC pediatrics
pub_type: 杂志文章
doi:10.1186/s12887-020-02304-5
更新日期:2020-09-02 00:00:00
abstract:BACKGROUND:Rhabdomyolysis is a potentially life-threatening syndrome that can develop from a variety of causes. The aim of the work is to analyze the clinical spectrum and to evaluate the prevalence of various etiologies in children, who present to the emergency department (ED) with rhabdomyolysis. METHODS:During a 6-...
journal_title:BMC pediatrics
pub_type: 杂志文章
doi:10.1186/1471-2431-13-134
更新日期:2013-09-03 00:00:00
abstract:BACKGROUND:In preterm infants with Respiratory Distress Syndrome (RDS), Less Invasive Surfactant Administration (LISA) has been established to reduce the need of mechanical ventilation and might improve survival rates without bronchopulmonary dysplasia. The aim of this study was to investigate whether NICU care has cha...
journal_title:BMC pediatrics
pub_type: 杂志文章
doi:10.1186/s12887-020-02325-0
更新日期:2020-09-03 00:00:00
abstract:BACKGROUND:Lung recruitment at birth has been advocated as an effective method of improving the respiratory transition at birth. Sustained inflations (SI) and dynamic positive end-expiratory pressure (PEEP) were assessed in clinical and animal studies to define the optimal level. Our working hypothesis was that very lo...
journal_title:BMC pediatrics
pub_type: 杂志文章
doi:10.1186/s12887-020-02055-3
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND:To determine the effect of human milk, maternal and donor, on in-hospital growth of very low birthweight (VLBW) infants. We performed a retrospective cohort study comparing in-hospital growth in VLBW infants by proportion of human milk diet, including subgroup analysis by maternal or donor milk type. Primary...
journal_title:BMC pediatrics
pub_type: 杂志文章
doi:10.1186/1471-2431-12-124
更新日期:2012-08-17 00:00:00
abstract:BACKGROUND:The study evaluates children in schools that participate in the School Health Program in the Northern region of Brazil with the objective of assessing whether their schools interfered in the development of overweight/obesity and how individual and school environment variables behave according to contextual a...
journal_title:BMC pediatrics
pub_type: 杂志文章
doi:10.1186/s12887-020-02096-8
更新日期:2020-04-28 00:00:00
abstract:BACKGROUND:The COVID-19 pandemic has disrupted healthcare systems worldwide. In addition to the direct impact of the virus on patient morbidity and mortality, the effect of lockdown strategies on health and healthcare utilization have become apparent. Little is known on the effect of the pandemic on pediatric and adole...
journal_title:BMC pediatrics
pub_type: 杂志文章
doi:10.1186/s12887-020-02303-6
更新日期:2020-09-07 00:00:00
abstract:BACKGROUND:Globally pneumonia is the leading cause of under-five child mortality. Several risk factors for pneumonia mortality have been identified, including delay in seeking health care. For successful reduction of delay in seeking healthcare, further evidence is crucial on its magnitude and factors associated with i...
journal_title:BMC pediatrics
pub_type: 杂志文章
doi:10.1186/s12887-019-1869-9
更新日期:2019-12-09 00:00:00
abstract:BACKGROUND:To determine the prevalence and severity of bone deficits in a cohort of childhood cancer survivors (CCS) compared to a healthy sibling control group, and the modifiable factors associated with bone deficits in CCS. METHODS:Cross-sectional study of bone health in 319 CCS and 208 healthy sibling controls. Bo...
journal_title:BMC pediatrics
pub_type: 杂志文章
doi:10.1186/1471-2431-12-40
更新日期:2012-03-28 00:00:00
abstract:BACKGROUND:Complications during pregnancy, childbirth and/or the postnatal period may result in the admission of a baby to a neonatal unit (NNU). While the survival and long-term prospects of high-risk infants are enhanced by admission, the enforced separation of the parent and child may have psychological consequences...
journal_title:BMC pediatrics
pub_type: 杂志文章
doi:10.1186/s12887-017-0917-6
更新日期:2017-07-11 00:00:00
abstract:BACKGROUND:Mutations in the PIGV, PIGO, PIGL, PIGY, PGAP2, PGAP3, and PIGW genes have recently been reported to cause hyperphosphatasia accompanied by mental retardation syndrome (HPMRS); the latter is an autosomal-recessive neurological disorder typically characterised by recurrent seizures, intellectual disability, a...
journal_title:BMC pediatrics
pub_type: 杂志文章
doi:10.1186/s12887-019-1440-8
更新日期:2019-02-27 00:00:00
abstract:BACKGROUND:Early detection of and intervention in childhood adversity has powerful potential to improve the health and well-being of children. A systematic review was conducted to better understand the pediatric health outcomes associated with childhood adversity. METHODS:PubMed, PsycArticles, and CINAHL were searched...
journal_title:BMC pediatrics
pub_type: 杂志文章,评审
doi:10.1186/s12887-018-1037-7
更新日期:2018-02-23 00:00:00
abstract:BACKGROUND:Stimulation is the most common intervention during neonatal resuscitation at birth, but scarce information is available on the actual methods, timing and efficacy of this basic step. To evaluate the occurrence, patterns and response to tactile stimulation at birth in a low-resource setting. METHODS:We revie...
journal_title:BMC pediatrics
pub_type: 杂志文章
doi:10.1186/s12887-018-1279-4
更新日期:2018-09-20 00:00:00
abstract:BACKGROUND:Obesity is a serious childhood health problem today. Studies have shown that overweight and obesity tend to be stable (track) from birth, through childhood and adolescence, to adulthood. However, existing studies are heterogeneous; there is still no consensus on the strength of the association between high b...
journal_title:BMC pediatrics
pub_type: 杂志文章
doi:10.1186/s12887-016-0599-5
更新日期:2016-05-10 00:00:00
abstract:BACKGROUND:The diagnosis of infantile hypertrophic pyloric stenosis (IHPS), although traditionally clinical, is now increasingly dependent on radiological corroboration. The rate of negative exploration in IHPS has been reported as 4%. The purpose of our study was to look at elements of supportive clinical evidence lea...
journal_title:BMC pediatrics
pub_type: 杂志文章
doi:10.1186/1471-2431-8-37
更新日期:2008-09-24 00:00:00
abstract:BACKGROUND:For treatment of Graf class IIb dysplastic hips at walking onset a treatment concept with abduction splints allowing patterns as walking and crawling under constant abduction control was investigated. However, as the splint still incapacitates child movements the research question remains whether the physiol...
journal_title:BMC pediatrics
pub_type: 杂志文章
doi:10.1186/1471-2431-5-17
更新日期:2005-06-15 00:00:00
abstract:BACKGROUND:Intussusception decreases blood flow to the bowel, and tissue hypoperfusion results in increased lactic acid levels. We aimed to determine whether lactic acid levels are associated with pediatric intussusception outcomes. METHODS:The electronic medical records of our emergency department pediatric patients ...
journal_title:BMC pediatrics
pub_type: 杂志文章
doi:10.1186/s12887-020-02095-9
更新日期:2020-04-24 00:00:00
abstract:BACKGROUND:In Brazil, the prevalence of prematurity has increased in recent years and it is a major cause of death in the neonatal period. Therefore, this study aims at assessing perinatal factors associated with early neonatal deaths in very low birth weight preterm infants born in a region of Brazil with low Human De...
journal_title:BMC pediatrics
pub_type: 杂志文章
doi:10.1186/s12887-014-0312-5
更新日期:2014-12-20 00:00:00
abstract:BACKGROUND:Coronavirus disease 2019 (COVID-19) has impacted the provision of health services in all specialties. We aim to study the impact of COVID-19 on the utilization of pediatric hospital services including emergency department (ED) attendances, hospitalizations, diagnostic categories and resource utilization in S...
journal_title:BMC pediatrics
pub_type: 杂志文章,多中心研究
doi:10.1186/s12887-020-02469-z
更新日期:2020-12-23 00:00:00
abstract:BACKGROUND:Infection causes neonatal mortality in both high and low income countries. While simple interventions to prevent neonatal infection are available, they are often poorly understood and implemented by clinicians. A basic understanding of healthcare providers' perceptions of infection control provides a platfor...
journal_title:BMC pediatrics
pub_type: 杂志文章
doi:10.1186/1471-2431-13-51
更新日期:2013-04-09 00:00:00
abstract:BACKGROUND:Oral antipyretics are commonly used to treat pediatric patients who develop fevers. However, patients presenting to the emergency department or undergoing surgery are frequently unable to tolerate oral antipyretics. Rectal formulations are available; however, this route of administration is unpredictable. Th...
journal_title:BMC pediatrics
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1186/s12887-017-0795-y
更新日期:2017-02-01 00:00:00
abstract:BACKGROUND:Seven years of age is a milestone for learning basic knowledge that is strongly related to attention abilities such as Alerting, Orienting, and Inhibition function, allowing for appropriate adaptation to primary school. These attention abilities are also influenced by gestational age at birth in a complex ma...
journal_title:BMC pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12887-018-1229-1
更新日期:2018-08-06 00:00:00
abstract:BACKGROUND:Daily pain and multi-site pain are both associated with reduction in work ability and health-related quality of life (HRQoL) among adults. However, no population-based studies have yet investigated the prevalence of daily and multi-site pain among adolescents and how these are associated with respondent char...
journal_title:BMC pediatrics
pub_type: 杂志文章
doi:10.1186/1471-2431-13-191
更新日期:2013-11-19 00:00:00
abstract:BACKGROUND:Prompt initiation of empiric therapy is common practice in case of suspected meningitis or encephalitis. However, in children the most common pathogens are viruses that usually do not require and are not covered by the applied anti-infective treatment. Novel multiplex PCR (mPCR) panels provide rapid on-site ...
journal_title:BMC pediatrics
pub_type: 杂志文章
doi:10.1186/s12887-020-1944-2
更新日期:2020-02-05 00:00:00
abstract:BACKGROUND:Imerslund-Gräsbeck syndrome is a rare genetic disease characterised by vitamin B12 deficiency and proteinuria. CASE PRESENTATION:A 4-year old Sri Lankan boy presented with gradually worsening difficulty in walking for two weeks duration. He was previously diagnosed and managed as having non-transfusion-depe...
journal_title:BMC pediatrics
pub_type: 杂志文章
doi:10.1186/s12887-021-02499-1
更新日期:2021-01-18 00:00:00
abstract:BACKGROUND:In order for infants and toddlers to meet recommended movement guidelines, their caregivers need to encourage play daily. This study used a qualitative approach to understand how mothers perceive and promote play and physical activity during the first 2 years of life. METHODS:Mothers with children between 0...
journal_title:BMC pediatrics
pub_type: 杂志文章
doi:10.1186/s12887-020-02321-4
更新日期:2020-09-09 00:00:00
abstract:BACKGROUND:Considerable heterogeneity has been observed in the selection and reporting of disease-specific pediatric outcome measures in randomized controlled trials (RCTs). This makes interpretation of results and comparison across trials challenging. Outcome measures in pediatric anaphylaxis trials have never previou...
journal_title:BMC pediatrics
pub_type: 杂志文章,评审
doi:10.1186/1471-2431-14-158
更新日期:2014-06-20 00:00:00
abstract:BACKGROUND:The Medical Home model recommends that Children with Special Health Care Needs (CSHCN) receive a medical care plan, outlining the child's major medical issues and care needs to assist with care coordination. While care plans are a primary component of effective care coordination, the creation and maintenance...
journal_title:BMC pediatrics
pub_type: 杂志文章
doi:10.1186/1471-2431-13-10
更新日期:2013-01-19 00:00:00
abstract:BACKGROUND:Sex comparisons between girls and boys in response to exercise in trained adolescents are missing and we investigated similarities and differences as a basis for clinical interpretation and guidance. METHODS:A total of 24 adolescent females and 27 adolescent males aged 13-19 years underwent a maximal bicycl...
journal_title:BMC pediatrics
pub_type: 杂志文章
doi:10.1186/1471-2431-12-127
更新日期:2012-08-20 00:00:00
abstract:BACKGROUND:In 2006, a new rotavirus vaccine (RotaTeq) was licensed in the US and recommended for routine immunization of all US infants. Because a previously licensed vaccine (Rotashield) was withdrawn from the US for safety concerns, identifying barriers to uptake of RotaTeq will help develop strategies to broaden vac...
journal_title:BMC pediatrics
pub_type: 杂志文章,多中心研究
doi:10.1186/1471-2431-7-32
更新日期:2007-10-18 00:00:00