Pharmacological interventions for prevention and management of delirium in intensive care patients: a systematic overview of reviews and meta-analyses.

abstract：OBJECTIVES:There is growing evidence that antihypertensive agents, particularly centrally acting ACE inhibitors (CACE-Is), which cross the blood-brain barrier, are associated with a reduced rate of cognitive decline. Given this, we compared the rates of cognitive decline in clinic patients with dementia receiving CACE-...

journal_title：BMJ open

authors： Gao Y,O'Caoimh R,Healy L,Kerins DM,Eustace J,Guyatt G,Sammon D,Molloy DW

更新日期：2013-07-25 00:00:00

abstract：OBJECTIVES:Differentiation of delirium and dementia is a key diagnostic challenge but there has been limited study of features that distinguish these conditions. We examined neuropsychiatric and neuropsychological symptoms in elderly medical inpatients to identify features that distinguish major neurocognitive disorder...

journal_title：BMJ open

authors： Leonard M,McInerney S,McFarland J,Condon C,Awan F,O'Connor M,Reynolds P,Meaney AM,Adamis D,Dunne C,Cullen W,Trzepacz PT,Meagher DJ

更新日期：2016-03-08 00:00:00

abstract：OBJECTIVES:To determine the availability of continuous positive airway pressure (CPAP) and to provide an overview of its use in neonatal units in government hospitals across India. SETTING:Cross-sectional cluster survey of a nationally representative sample of government hospitals from across India. PRIMARY OUTCOMES:...

journal_title：BMJ open

authors： Dewez JE,Nangia S,Chellani H,White S,Mathai M,van den Broek N

更新日期：2020-02-28 00:00:00

abstract：PURPOSE:The Buffalo Osteoporosis and Periodontal Disease (OsteoPerio) study is a prospective cohort study focused on the relationship between the microbiome and oral and systemic health outcomes in postmenopausal women. The cohort was established to examine how the oral microbiome is affected by (and how it affects) pe...

journal_title：BMJ open

authors： Banack HR,Genco RJ,LaMonte MJ,Millen AE,Buck MJ,Sun Y,Andrews CA,Hovey KM,Tsompana M,McSkimming DI,Zhao J,Wactawski-Wende J,OsteoPerio Study Group.

更新日期：2018-12-04 00:00:00

abstract：OBJECTIVES:(1) Summarise chest ultrasound accuracy to diagnose radiological consolidation, referenced to chest CT in patients with acute respiratory failure (ARF). (2) Directly compared ultrasound with chest X-ray. SETTING:Hospitalised patients. PARTICIPANTS:Studies were eligible if adult participants in respiratory ...

journal_title：BMJ open

authors： Hew M,Corcoran JP,Harriss EK,Rahman NM,Mallett S

更新日期：2015-05-19 00:00:00

abstract：INTRODUCTION:Improving healthcare for all is one of the global health priorities, particularly in disease burdened settings such as sub-Saharan Africa (SSA). Considering the high penetration rate of mobile phones in SSA, mobile health (mHealth) could be used to achieve universal health coverage. The proposed study will...

journal_title：BMJ open

authors： Osei E,Kuupiel D,Mashamba-Thompson TP

更新日期：2020-10-20 00:00:00

abstract：OBJECTIVES:Childhood asthma is a complex condition where many environmental factors are implicated in causation. The aim of this study was to complete a systematic review of the literature describing associations between environmental exposures and the development of asthma in young children. SETTING:A systematic revi...

journal_title：BMJ open

authors： Dick S,Friend A,Dynes K,AlKandari F,Doust E,Cowie H,Ayres JG,Turner SW

更新日期：2014-11-24 00:00:00

abstract：OBJECTIVE:The study aimed to determine if and how environmental factors correlated with asthma admission rates in geographically different parts of Guangxi province in China. SETTING:Guangxi, China. PARTICIPANTS:This study was done among 7804 asthma patients. PRIMARY AND SECONDARY OUTCOME MEASURES:Spearman correlati...

journal_title：BMJ open

authors： Ma R,Liang L,Kong Y,Chen M,Zhai S,Song H,Hou Y,Zhang G

更新日期：2020-10-07 00:00:00

abstract：OBJECTIVE:To map out the current provision of interventional oncology (IO) services in the UK. DESIGN:Cross-sectional multicentre study. SETTING:All National Health Service (NHS) trusts in England and Scottish, Welsh and Northern Ireland health boards. PARTICIPANTS:Interventional radiology (IR) departments in all NH...

journal_title：BMJ open

authors： Zhong J,Atiiga P,Alcorn DJ,Kay D,Illing R,Breen DJ,Railton N,McCafferty IJ,Haslam PJ,Wah TM

更新日期：2017-10-22 00:00:00

abstract：OBJECTIVES:The aim of this study was to explore the experiences of doctors and nurses caring for patients with delirium in the intensive care unit (ICU) and to describe the process of delirium management. SETTING:This study was performed in 5 ICUs located within 4 hospitals in Madrid (Spain). PARTICIPANTS:Purposeful ...

journal_title：BMJ open

authors： Palacios-Ceña D,Cachón-Pérez JM,Martínez-Piedrola R,Gueita-Rodriguez J,Perez-de-Heredia M,Fernández-de-las-Peñas C

更新日期：2016-01-29 00:00:00

abstract：OBJECTIVES:The Maine Diversion Alert Program grants healthcare providers access to law enforcement data on drug charges. The objectives of this report were to analyse variations in drug charges by demographics and examine recent trends in arrests, prescriptions of controlled substances and overdoses. DESIGN:Observatio...

journal_title：BMJ open

authors： Simpson KJ,Moran MT,Foster ML,Shah DT,Chung DY,Nichols SD,McCall KL,Piper BJ

更新日期：2019-04-29 00:00:00

abstract：INTRODUCTION:Multimorbidity (MM) refers to the coexistence of two or more chronic conditions within one person, where no one condition is considered primary. As populations age and healthcare provision improves, MM is becoming increasingly common and poses a challenge to the single morbidity approach to illness managem...

journal_title：BMJ open

authors： Slattery BW,O'Connor L,Haugh S,Dwyer CP,O'Higgins S,Caes L,Egan J,McGuire BE

更新日期：2017-01-18 00:00:00

abstract：BACKGROUND:Genetic risk assessment for breast cancer and ovarian cancer (BCOC) is expected to make major inroads into mainstream clinical practice. It is important to evaluate the potential impact on women ahead of its implementation in order to maximise health benefits, as predictive genetic testing without adequate s...

journal_title：BMJ open

authors： Meisel SF,Fraser LSM,Side L,Gessler S,Hann KEJ,Wardle J,Lanceley A,PROMISE study team.

更新日期：2017-12-22 00:00:00

abstract：OBJECTIVES:Stroke is the leading cause of death and disability in China, but there is scare of evidence on whether and to what extent comorbidity affects the stroke-related costs in health system. We examined the association between comorbidity and stroke-related health service utilisation and costs in urban China. SE...

journal_title：BMJ open

authors： Ding R,Zhu D,Ma Y,Shi X,He P

更新日期：2020-12-10 00:00:00

abstract：:Background and objective The birth of a preterm infant can be an overwhelming experience of guilt, fear and helplessness for parents. Provision of interventions to support and engage parents in the care of their infant may improve outcomes for both the parents and the infant. The objective of this systematic review is...

journal_title：BMJ open

authors： Brett J,Staniszewska S,Newburn M,Jones N,Taylor L

更新日期：2011-06-02 00:00:00

abstract：OBJECTIVES:The aim of this study was to investigate the associations between surrounding greenness levels and asthma among children, and to explore a possible change of this association by the distance of the residence to a city park. DESIGN:A nested case-control study. SETTING:Children aged 4-6 years residing at the...

journal_title：BMJ open

authors： Andrusaityte S,Grazuleviciene R,Kudzyte J,Bernotiene A,Dedele A,Nieuwenhuijsen MJ

更新日期：2016-04-11 00:00:00

abstract：OBJECTIVE:To develop a novel sex independent anthropometric index, termed as angle index, related to type 2 diabetes. DESIGN:Case-control. PARTICIPANTS:The study comprised 121 participants and were divided into two groups. One group had no form of diabetes and served as controls (n=50). The other group had the condit...

journal_title：BMJ open

authors： Ramnanansingh TG,Nayak SB

更新日期：2019-02-19 00:00:00

abstract：OBJECTIVES:We investigated the clinical characteristics of patients with stroke recurrence in the first year after cardioembolic stroke, and determined the predictors associated with recurrence. DESIGN:A prospective cohort study. SETTING:Multicentre study at the Fukuoka prefecture in Japan. PARTICIPANTS:We enroled 2...

journal_title：BMJ open

authors： Kuwashiro T,Sugimori H,Ago T,Kuroda J,Kamouchi M,Kitazono T,FSR Investigators (see appendix).

更新日期：2013-11-14 00:00:00

abstract：OBJECTIVES:To examine the damage location distribution of five main body region injuries of maximum abbreviated injury score (MAIS) 3-6 injured occupants for nearside struck vehicle in front-to-side impact crashes. DESIGN AND SETTING:MAIS 3-6 injured occupants information was extracted from the US-National Automotive ...

journal_title：BMJ open

authors： Tang Y,Cao L,Kan S

更新日期：2014-05-08 00:00:00

abstract：OBJECTIVE:The National Institute for Occupation Safety and Health-administered Coal Workers' Health Surveillance Program (CWHSP) provides radiographic pneumoconiosis screening for US coal miners. Radiographs are classified by readers according to International Labour Office criteria. In addition to pneumoconiotic paren...

journal_title：BMJ open

authors： Halldin CN,Hale JM,Blackley DJ,Laney AS

更新日期：2017-08-11 00:00:00

abstract：INTRODUCTION:Expectant mothers in low-income and middle-income countries often lack access to vital information about pregnancy, preparation for birth and best practices when caring for their newborn. Innovative solutions are needed to bridge this knowledge gap and dramatically improve maternal and neonatal health in t...

journal_title：BMJ open

authors： Su Y,Yuan C,Zhou Z,Heitner J,Campbell B

更新日期：2016-08-10 00:00:00

abstract：OBJECTIVES:Few studies of tornado injuries have considered differences related to damage levels and Enhanced-Fujita (EF) scale ratings. This study aimed to evaluate the pattern, spectrum and geographical distribution of injuries related to the Yancheng tornado and provide guidelines for effective emergency medical stra...

journal_title：BMJ open

authors： Deng Q,Lv Y,Xue C,Kang P,Dong J,Zhang L

更新日期：2018-06-22 00:00:00

abstract：OBJECTIVES:To analyse the prevalence and incidence of pregabalin and gabapentin (P/G) prescriptions, typical therapeutic uses of P/G with special attention to pain-related diagnoses and discontinuation rates. DESIGN:Secondary data analysis. SETTING:Primary and secondary care in Germany. PARTICIPANTS:Four million pat...

journal_title：BMJ open

authors： Viniol A,Ploner T,Hickstein L,Haasenritter J,Klein KM,Walker J,Donner-Banzhoff N,Becker A

更新日期：2019-03-30 00:00:00

abstract：INTRODUCTION:Nursing bedside handover in hospital has been identified as an opportunity to involve patients and promote patient-centred care. It is important to consider the preferences of both patients and nurses when implementing bedside handover to maximise the successful uptake of this policy. We outline a study wh...

journal_title：BMJ open

authors： Spinks J,Chaboyer W,Bucknall T,Tobiano G,Whitty JA

更新日期：2015-11-11 00:00:00

abstract：OBJECTIVE:To examine geographic variation in use of surgery for female stress urinary incontinence (SUI), mainly midurethral mesh tape insertions, in the English National Health Service (NHS). DESIGN:National cohort study. SETTING:NHS hospitals. PARTICIPANTS:27 997 women aged 20 years or older who had a first SUI su...

journal_title：BMJ open

authors： Mamza JB,Geary RS,El-Hamamsy D,Cromwell DA,Duckett J,Monga A,Toozs-Hobson P,Mahmood T,Wilson A,Tincello DG,van der Meulen JH,Gurol Urganci I

更新日期：2019-08-28 00:00:00

abstract：OBJECTIVE:This study aimed to investigate the association between the use of isotretinoin and the risk of depression in patients with acne. DESIGN:This was a meta-analysis in which the standardised mean difference (SMD) and the relative risk (RR) were used for data synthesis employing the random-effects model. SETTIN...

journal_title：BMJ open

authors： Li C,Chen J,Wang W,Ai M,Zhang Q,Kuang L

更新日期：2019-01-21 00:00:00

abstract：OBJECTIVE:The current study aimed to better understand trends and risk factors associated with non-fatal drowning of infants and children in the USA using two large, national databases. METHODS:A secondary data analysis was conducted using the National Inpatient Sample and the Nationwide Emergency Department Sample da...

journal_title：BMJ open

authors： Felton H,Myers J,Liu G,Davis DW

更新日期：2015-12-15 00:00:00

abstract：OBJECTIVES:To define the core competencies essential for specialist training in neurocritical care in China. DESIGN:Modified Delphi method and nominal group (NG) technique. SETTING:National. PARTICIPANTS:A total of 1094 respondents from 33 provinces in China participated in the online survey. A NG of 11 members was ...

journal_title：BMJ open

authors： Cui Z,Gao L,Huang QB,Li LH,Qiu BH,Shi GZ,Yu XY,Wang Y,Zhang L,Wang Y,Zhang L,Zhou JX,Working Group from Neuro-Critical Care Committee affiliated to the Chinese Association of Critical Care Physicians and the National Center for H

更新日期：2020-01-06 00:00:00

abstract：OBJECTIVES:Identifying the issues and concerns that matter most to burns survivors can be challenging. For a number of reasons, but mainly relating to patient empowerment, some of the most pressing concerns patients may have during a clinical encounter may not naturally be the focal point of that encounter. The Patient...

journal_title：BMJ open

authors： Gibson JAG,Yarrow J,Brown L,Evans J,Rogers SN,Spencer S,Shokrollahi K

更新日期：2019-12-30 00:00:00

abstract：OBJECTIVE:Pregnancy, birth and health complications, maternal mental health problems following preterm birth and their possible impact on early mother-infant interaction at 6 and 18 months corrected age (CA) were explored. Predictors of mother-infant interaction at 18 months CA were identified. DESIGN AND METHODS:This...

journal_title：BMJ open

authors： Misund AR,Bråten S,Nerdrum P,Pripp AH,Diseth TH

更新日期：2016-05-04 00:00:00