Zonal T2* and T1Gd assessment of knee joint cartilage in various histological grades of cartilage degeneration: an observational in vitro study.

abstract：PURPOSE:Progression of stable coronary artery disease (CAD) towards acute coronary syndrome (ACS) is a dynamic and heterogeneous process with many intertwined constituents, in which a plaque destabilising sequence could lead to ACS within short time frames. Current CAD risk assessment models, however, are not designed ...

journal_title：BMJ open

authors： Oemrawsingh RM,Akkerhuis KM,Umans VA,Kietselaer B,Schotborgh C,Ronner E,Lenderink T,Liem A,Haitsma D,van der Harst P,Asselbergs FW,Maas A,Oude Ophuis AJ,Ilmer B,Dijkgraaf R,de Winter RJ,The SH,Wardeh AJ,Hermans W,Cr

更新日期：2016-12-23 00:00:00

abstract：BACKGROUND:Osteoporosis is an age-related disease with progressive loss of bone, leading to fragile bone. It is one of the major health issues in older adults and causes medical, social and economic impacts globally. Patients with osteoporosis have high risk of osteoporotic fractures. Low-magnitude high-frequency vibra...

journal_title：BMJ open

authors： Chow SKH,Ho CY,Wong HW,Chim YN,Wong RWM,Cheung WH

更新日期：2020-12-15 00:00:00

abstract：OBJECTIVE:To investigate the length of time taken to open UK research sites in multicentre clinical trials and to identify reasons for any delays. DESIGN:A case study, recording key milestone dates from the time a site receives ethical approval through to opening to recruitment. Delay reasons were prospectively logged...

journal_title：BMJ open

authors： Kearney A,McKay A,Hickey H,Balabanova S,Marson AG,Gamble C,Williamson P

更新日期：2014-09-16 00:00:00

abstract：OBJECTIVES:Mortality rates in Scotland are higher, and health inequalities are greater, than in the rest of Western and Central Europe. There was a marked divergence during the 1980s and 1990s in the Scottish rates partly due to rises in alcohol-related and drug-related deaths, suicide and deaths by assault. This study...

journal_title：BMJ open

authors： Parkinson J,Minton J,McCartney G

更新日期：2020-02-09 00:00:00

abstract：OBJECTIVES:Given many countries' ageing populations, policymakers must consider how to mitigate or reduce health problems associated with old age, within budgetary constraints. Evidence of use of digital technology in delaying the onset of illness and reducing healthcare service use is mixed, with no clear consensus as...

journal_title：BMJ open

authors： Clarke CS,Round J,Morris S,Kharicha K,Ford J,Manthorpe J,Iliffe S,Goodman C,Walters K

更新日期：2017-07-21 00:00:00

abstract：PURPOSE:The ChicagO Multiethnic Prevention and Surveillance Study or 'COMPASS' is a population-based cohort study with a goal to examine the risk and determinants of cancer and chronic disease. COMPASS aims to address factors causing and/or exacerbating health disparities using a precision health approach by recruiting...

journal_title：BMJ open

authors： Aschebrook-Kilfoy B,Kibriya MG,Jasmine F,Stepniak L,Gopalakrishnan R,Craver A,Zakin P,Tasmin S,Kim KE,Goss KH,List M,LeBeau M,Ahsan H

更新日期：2020-09-16 00:00:00

abstract：OBJECTIVES:To calculate the prevalence of disabling chronic pain (DCP) and to offer a more representative and accurate estimation by applying different calibration techniques. SETTINGS:2011 Andalusian Health Survey, a cross-sectional population survey based on face-to-face home interviews. PARTICIPANTS:6507 people ag...

journal_title：BMJ open

authors： Cabrera-León A,Rueda M,Cantero-Braojos M

更新日期：2017-01-30 00:00:00

abstract：INTRODUCTION:Endometriosis is a common gynaecological disease characterised by pain and subfertility. Randomised controlled trials evaluating treatments for endometriosis have reported many different outcomes and outcome measures. This variation restricts effective data synthesis limiting the usefulness of research to ...

journal_title：BMJ open

authors： Hirsch M,Duffy JM,Barker C,Hummelshoj L,Johnson NP,Mol B,Khan KS,Farquhar C,International Collaboration to Harmonize Outcomes and Measures for Endometriosis (iHOME).

更新日期：2016-12-21 00:00:00

abstract：OBJECTIVE:To explore the perspectives of primary healthcare (PHC) professionals providing care to refugees through mainstream general practice. DESIGN:Qualitative exploratory design with semistructured interviews subjected to inductive thematic analysis. SETTING AND PARTICIPANTS:Nine general practices enrolled in the...

journal_title：BMJ open

authors： Richard L,Richardson G,Jaye C,Stokes T

更新日期：2019-12-31 00:00:00

abstract：INTRODUCTION:Although the colorectal cancer (CRC) mortality rate has significantly improved over the past several decades, many patients will have a recurrence following curative treatment. Despite this high risk of recurrence, adherence to CRC surveillance testing guidelines is poor which increases cancer-related morb...

journal_title：BMJ open

authors： Hines RB,Jiban MJH,Choudhury K,Loerzel V,Specogna AV,Troy SP,Zhang S

更新日期：2018-04-28 00:00:00

abstract：OBJECTIVE:The association between obesity and disability may differ between high-income and low-income/middle-income countries but there are no studies comparing this association between these settings. The aim of the study was to assess this association in nine countries using nationally-representative data from the C...

journal_title：BMJ open

authors： Koyanagi A,Moneta MV,Garin N,Olaya B,Ayuso-Mateos JL,Chatterji S,Leonardi M,Sainio P,Galas A,Haro JM

更新日期：2015-04-02 00:00:00

abstract：OBJECTIVES:Evidence comparing the effectiveness of surgical and conservative treatment of symptomatic lumbar disc herniation is controversial. We sought to compare short-term and long-term effectiveness of surgical and conservative treatment in sciatica symptom severity and quality of life in patients with lumbar disc ...

journal_title：BMJ open

authors： Gugliotta M,da Costa BR,Dabis E,Theiler R,Jüni P,Reichenbach S,Landolt H,Hasler P

更新日期：2016-12-21 00:00:00

abstract：OBJECTIVES:Complementary and alternative medicine (CAM) is frequently used in Western countries within general medicine and internal medicine. Information on the use in orthopaedic and trauma surgery is widely lacking. The aim of this study was to investigate usage and needs regarding CAM for these patients. DESIGN:Pr...

journal_title：BMJ open

authors： Kilper A,Müller A,Huber R,Reimers N,Schütz L,Lederer AK

更新日期：2020-09-06 00:00:00

abstract：OBJECTIVES:Social interaction may be particularly important for people with chronic health conditions, due to the numerous benefits to an individual's health. This paper aims to determine if labour force participation is a factor that influences individuals with chronic health conditions partaking in social or cultural...

journal_title：BMJ open

authors： Callander E,Schofield DJ

更新日期：2013-01-30 00:00:00

abstract：INTRODUCTION:The first-line recommended treatment for patients with intermittent claudication (IC) is a supervised exercise programme (SEP), which includes a minimum of 2-hours of exercise per week over a 12-week period. However, provision, uptake and adherence rates for these SEP programmes are poor, with time constra...

journal_title：BMJ open

authors： Pymer S,Harwood A,Ibeggazene S,McGregor G,Huang C,Twiddy M,Nicholls AR,Ingle L,Carroll S,Long J,Rooms M,Chetter IC,INITIATE investigator group.

更新日期：2020-07-06 00:00:00

abstract：OBJECTIVES:The clinical course and prognosis of follicular lymphoma (FL) are diverse and associated with the patient's immune response. We investigated the lymphocyte-to-monocyte ratio (LMR) and neutrophil-to-lymphocyte ratio (NLR) as prognostic factors in patients with FL, including those receiving radiotherapy. DESI...

journal_title：BMJ open

authors： Lee SF,Luque-Fernandez MA

更新日期：2017-11-03 00:00:00

abstract：OBJECTIVES:To explore the association of dietary behaviour factors on obesity among city, township and rural area adults. SETTING:A stratified cluster sampling technique was employed in the present cross-sectional study. On the basis of socioeconomic characteristics, two cities, two townships and two residential villa...

journal_title：BMJ open

authors： Zou Y,Zhang R,Zhou B,Huang L,Chen J,Gu F,Zhang H,Fang Y,Ding G

更新日期：2015-07-15 00:00:00

abstract：INTRODUCTION:The mainstay treatment for reducing the symptoms of angina and long-term risk of heart attacks in patients with heart disease is stent implantation in the diseased coronary artery. While this procedure has revolutionised treatment, the incidence of secondary events remains a concern. These repeat events ar...

journal_title：BMJ open

authors： Rathod KS,Jones DA,Van-Eijl TJ,Tsang H,Warren H,Hamshere SM,Kapil V,Jain AK,Deaner A,Poulter N,Caulfield MJ,Mathur A,Ahluwalia A

更新日期：2016-12-20 00:00:00

abstract：INTRODUCTION:Clinical depression is a substantial problem among adolescents, increasing significantly at about age 15 years. It causes impairment in social, academic and familial relationships, as well as ongoing cognitive and emotional difficulties for the individual. A study in Iceland demonstrated that a cognitive-b...

journal_title：BMJ open

authors： Wikberg C,Augustsson P,Sveinsdottir G,Craighead WE,Arnarson EÖ,Marteinsdottir I,Lilja JL

更新日期：2021-01-22 00:00:00

abstract：OBJECTIVES:To investigate the impact of first eye and second eye cataract surgery on the level of physical activity undertaken by older adults with bilateral cataract. DESIGN:Prospective cohort study. SETTING:Three public ophthalmology clinics in Western Australia. PARTICIPANTS:Fifty-five older adults with bilateral...

journal_title：BMJ open

authors： Meuleners LB,Feng YR,Fraser M,Brameld K,Chow K

更新日期：2019-03-20 00:00:00

abstract：OBJECTIVES:We investigated the clinical characteristics of patients with stroke recurrence in the first year after cardioembolic stroke, and determined the predictors associated with recurrence. DESIGN:A prospective cohort study. SETTING:Multicentre study at the Fukuoka prefecture in Japan. PARTICIPANTS:We enroled 2...

journal_title：BMJ open

authors： Kuwashiro T,Sugimori H,Ago T,Kuroda J,Kamouchi M,Kitazono T,FSR Investigators (see appendix).

更新日期：2013-11-14 00:00:00

abstract：OBJECTIVES:Medical image analysis practices face challenges that can potentially be addressed with algorithm-based segmentation tools. In this study, we map the field of automatic MR brain lesion segmentation to understand the clinical applicability of prevalent methods and study designs, as well as challenges and limi...

journal_title：BMJ open

authors： Gryska E,Schneiderman J,Björkman-Burtscher I,Heckemann RA

更新日期：2021-01-29 00:00:00

abstract：INTRODUCTION:The Bristol Stool Form Scale (BSS) which consists of 7 photographs of different stool forms allows assessment of stool consistency (scale 1 for hard lumps to scale 7 for watery stools), in an objective manner in adults. The BSS is also sometimes used to characterise the stools of infants and young children...

journal_title：BMJ open

authors： Vandenplas Y,Szajewska H,Benninga M,Di Lorenzo C,Dupont C,Faure C,Miqdadi M,Osatakul S,Ribes-Konickx C,Saps M,Shamir R,Staiano A,BITSS Study Group.

更新日期：2017-03-29 00:00:00

abstract：INTRODUCTION:Chronic subdural haematomas (CSDHs) are one of the most common neurosurgical conditions. The goal of surgery is to alleviate symptoms and minimise the risk of symptomatic recurrences. In the past, reoperation rates as high as 20%-30% were described for CSDH recurrences. However, following the introduction ...

journal_title：BMJ open

authors： Tommiska P,Raj R,Schwartz C,Kivisaari R,Luostarinen T,Satopää J,Taimela S,Järvinen T,Ranstam J,Frantzen J,Posti J,Luoto TM,Leinonen V,Tetri S,Koivisto T,Lönnrot K

更新日期：2020-06-21 00:00:00

abstract：OBJECTIVE:Providing services to rural dwelling minority cultural groups with serious chronic disease is challenging due to access to care and cultural differences. This study aimed to describe service providers' perspectives on health services delivery for Aboriginal people receiving haemodialysis for end-stage kidney ...

journal_title：BMJ open

authors： Rix EF,Barclay L,Wilson S,Stirling J,Tong A

更新日期：2013-10-23 00:00:00

abstract：OBJECTIVES:Livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) emergence is a major public health concern. This study was aimed at assessing risk factors for persistently carrying MRSA in veal calf farmers and their family members. We also evaluate the dynamics of MRSA environmental load during t...

journal_title：BMJ open

authors： Dorado-García A,Bos ME,Graveland H,Van Cleef BA,Verstappen KM,Kluytmans JA,Wagenaar JA,Heederik DJ

更新日期：2013-09-19 00:00:00

abstract：OBJECTIVES:To examine the effect on estimated levels of health conditions produced from large-scale surveys, when either list-wise respondent deletion or standard demographic item-level imputation is employed. To assess the degree to which further bias reduction results from the inclusion of correlated ancillary variab...

journal_title：BMJ open

authors： Frankel MR,Battaglia MP,Balluz L,Strine T

更新日期：2012-07-12 00:00:00

abstract：OBJECTIVES:Low serum amylase (LSA) was reported to be associated with obesity, metabolic syndrome (MetS) and diabetes. However, it is unknown as to whether LSA is associated with non-alcoholic fatty liver disease (NAFLD), a hepatic manifestation of MetS and insulin resistance. Therefore, we performed a clinical epidemi...

journal_title：BMJ open

authors： Nakajima K,Oshida H,Muneyuki T,Saito M,Hori Y,Fuchigami H,Kakei M,Munakata H

更新日期：2013-01-03 00:00:00

abstract：OBJECTIVES:Use of the term 'patient' has been recently debated, compared with alternatives including 'consumer' and 'client'. This scoping study aimed to provide an integrated view of preferred labels across healthcare contexts and countries to clarify labelling preferences of individuals accessing healthcare. DESIGN:...

journal_title：BMJ open

authors： Costa DSJ,Mercieca-Bebber R,Tesson S,Seidler Z,Lopez AL

更新日期：2019-03-07 00:00:00

abstract：OBJECTIVES:Acute respiratory infections (ARIs) are a global cause of childhood morbidity. We compared temporal trends and socioeconomic disparities for ARI hospitalisations in young children across Western Australia, England and Scotland. DESIGN:Retrospective population-based cohort studies using linked birth, death a...

journal_title：BMJ open

authors： Moore HC,de Klerk N,Blyth CC,Gilbert R,Fathima P,Zylbersztejn A,Verfürden M,Hardelid P

更新日期：2019-05-19 00:00:00