The elevated levels of urinary angiotensinogen are correlated with the severity of idiopathic membranous nephropathy.

abstract：BACKGROUND:Current guidelines regarding plasma-sampling techniques for glomerular filtration rate (GFR) determination are inconsistent. Single-sample methods are commonly believed not to be precise enough to meet clinical demands. The present study compared the agreement between single- and dual- plasma sampling method...

journal_title：BMC nephrology

authors： Zhang Y,Sui Z,Yu Z,Li TF,Feng WY,Zuo L

更新日期：2018-07-11 00:00:00

abstract：BACKGROUND:Cancer-related thrombotic microangiopathy (CR-TMA) is a rare entity associated with a dismal prognosis. Usually, CR-TMA is associated with mucin-producing carcinomas among which stomach, breast, prostate, lung and pancreas tumours are the most frequent. CASES PRESENTATION:We describe for the first time thre...

journal_title：BMC nephrology

authors： de Nattes T,Moreau-Grangé L,Vezzosi D,Hadoux J,Hie M,Guerrot D,Grangé S

更新日期：2020-01-30 00:00:00

abstract：BACKGROUND:Patients undergoing liver transplantation with preexisting renal dysfunction are prone to further renal impairment with the early postoperative use of Calcineurin-inhibitors. However, there is only little scientific evidence for the safety and efficacy of de novo CNI free "bottom-up" regimens in patients wit...

journal_title：BMC nephrology

authors： Schnitzbauer AA,Scherer MN,Rochon J,Sothmann J,Farkas SA,Loss M,Geissler EK,Obed A,Schlitt HJ

更新日期：2010-09-14 00:00:00

abstract：BACKGROUND:Bone Morphogenetic Protein (BMP)-7 is protective in different animal models of acute and chronic kidney disease. Its role in human kidneys, and in particular hypertensive nephrosclerosis, has thus far not been described. METHODS:BMP-7 mRNA was quantified using real-time PCR and localised by immunostaining i...

journal_title：BMC nephrology

authors： Bramlage CP,Tampe B,Koziolek M,Maatouk I,Bevanda J,Bramlage P,Ahrens K,Lange K,Schmid H,Cohen CD,Kretzler M,Müller GA

更新日期：2010-11-16 00:00:00

abstract：BACKGROUND:Atherosclerosis is regarded as a combination of two major separate diseases: atherosis and sclerosis. Sclerotic component depends on deterioration of elastic properties of the aortic wall and is called aortic stiffness. The most valuable, non-invasive method of aortic stiffness assessment is echocardiography...

journal_title：BMC nephrology

authors： Zapolski T,Furmaga J,Jaroszyński A,Wysocka A,Rudzki S,Wysokiński AP

更新日期：2017-01-23 00:00:00

abstract：BACKGROUND:Despite lithium being the most efficacious treatment for bipolar disorder, its use has been decreasing at least in part due to concerns about its potential to cause significant nephrotoxicity. Whilst the ability of lithium to cause nephrogenic diabetes insipidus is well established, its ability to cause chro...

journal_title：BMC nephrology

authors： Davis J,Desmond M,Berk M

更新日期：2018-11-03 00:00:00

abstract：BACKGROUND:Bordetella pertussis infection is a known trigger of atypical hemolytic uremic syndrome (HUS). For patients suspected of having atypical HUS, prompt plasma exchange/infusion (PE/PI) or eculizumab (ECZ) treatment is recommended. CASE PRESENTATION:We report a 1-month-old female infant who was admitted with a ...

journal_title：BMC nephrology

authors： Saida K,Ogura M,Kano Y,Ishimori S,Yoshikawa T,Nagata H,Sato M,Kamei K,Ishikura K

更新日期：2018-12-17 00:00:00

abstract：BACKGROUND:The current practice concerning timing, mode, and dose of renal replacement therapy (RRT) in patients with metformin-associated lactic acidosis (MALA) with renal failure remains unknown. To investigate whether serum lactate level and prescription pattern of RRT are associated with mortality in patients with ...

journal_title：BMC nephrology

authors： Yeh HC,Ting IW,Tsai CW,Wu JY,Kuo CC

更新日期：2017-07-10 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) and end-stage renal disease (ESRD) represent worldwide health problems with an epidemic extent. Therefore, attention must be given to the optimisation of patient care, as gaps in the care of CKD and ESRD patients are well documented. As part of a multidisciplinary patient care st...

journal_title：BMC nephrology

authors： Stemer G,Lemmens-Gruber R

更新日期：2011-07-22 00:00:00

abstract：BACKGROUND:The clinical consequences of starting chronic peritoneal dialysis (PD) after emergent dialysis via a temporary hemodialysis (HD) catheter has rarely been evaluated within a full spectrum of treated end-stage renal disease (ESRD). We investigated the longer-term outcomes of patients undergoing emergent-start ...

journal_title：BMC nephrology

authors： Li WY,Wang YC,Hwang SJ,Lin SH,Wu KD,Chen YM

更新日期：2017-12-11 00:00:00

abstract：BACKGROUND:Observational studies have demonstrated an association between nephrolithiasis and hypertension. The aim of this meta-analysis was to summarize all available evidence. METHODS:PubMed, EMBASE, the Cochrane Central Register of Controlled Trials databases, and the reference lists of relevant articles were sear...

journal_title：BMC nephrology

authors： Shang W,Li Y,Ren Y,Yang Y,Li H,Dong J

更新日期：2017-11-29 00:00:00

abstract：BACKGROUND:The effect of chronic hepatitis B virus (HBV) infection on the risk of chronic kidney disease (CKD) is controversial. We examined the prospective association between hepatitis B surface antigen (HBsAg) serology status and incident CKD in a large cohort of men and women. METHODS:Cohort study of 299,913 adult...

journal_title：BMC nephrology

authors： Hong YS,Ryu S,Chang Y,Caínzos-Achirica M,Kwon MJ,Zhao D,Shafi T,Lazo M,Pastor-Barriuso R,Shin H,Cho J,Guallar E

更新日期：2018-12-11 00:00:00

abstract：BACKGROUND:For chronic hemodialysis, the ideal permanent vascular access is the arteriovenous fistula (AVF). Temporary catheters should be reserved for acute dialysis needs. The AVF is associated with lower infection rates, better clinical results, and a higher quality of life and survival when compared to temporary ca...

journal_title：BMC nephrology

authors： Bonfante GM,Gomes IC,Andrade EI,Lima EM,Acurcio FA,Cherchiglia ML

更新日期：2011-11-17 00:00:00

abstract：BACKGROUND:It has been reported that people living with HIV in West Africa exhibited the highest risks for chronic kidney disease (CKD) in the world. Here, we aimed at determining the CKD frequency and changes in kidney function during antiretroviral treatment (ART) in a large cohort of HIV-patients followed in Burkina...

journal_title：BMC nephrology

authors： Kaboré NF,Poda A,Zoungrana J,Da O,Ciaffi L,Semdé A,Yaméogo I,Sawadogo AB,Delaporte E,Meda N,Limou S,Cournil A

更新日期：2019-05-07 00:00:00

abstract：BACKGROUND:Although chronic kidney disease (CKD) affects a growing number of people, epidemiologic data on incident CKD in the general population are scarce. Screening strategies to increase early CKD detection have been developed. METHODS:From a community-based sample of 4,409 individuals residing in a well-defined g...

journal_title：BMC nephrology

authors： Ayav C,Beuscart JB,Briançon S,Duhamel A,Frimat L,Kessler M

更新日期：2016-11-15 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) is characterized by dysbiosis, elevated levels of uremic toxins, systemic inflammation, and increased markers of oxidative stress. These factors lead to an increased risk of cardiovascular disease (CVD) which is common among CKD patients. Supplementation with high amylose maize r...

journal_title：BMC nephrology

authors： Headley SA,Chapman DJ,Germain MJ,Evans EE,Hutchinson J,Madsen KL,Ikizler TA,Miele EM,Kirton K,O'Neill E,Cornelius A,Martin B,Nindl B,Vaziri ND

更新日期：2020-11-26 00:00:00

abstract：BACKGROUND:Chloride is speculated to have nephrotoxic properties. In healthy subjects we tested the hypothesis that acute chloride loading with 3% saline would induce kidney injury, which could be prevented with the loop-diuretic furosemide. METHODS:The study was designed as a randomized, placebo-controlled, crossover...

journal_title：BMC nephrology

authors： Mose FH,Jörgensen AN,Vrist MH,Ekelöf NP,Pedersen EB,Bech JN

更新日期：2019-06-03 00:00:00

abstract：BACKGROUND:Aciduria caused by urinary excretion of acidic metabolic wastes produced in daily life is known to be augmented in patients with chronic kidney disease (CKD). To evaluate the reno-protective effect of oral alkalizing agents for the improvement of metabolic acidosis and neutralization of intratubular pH in th...

journal_title：BMC nephrology

authors： Abe M,Akaishi T,Shoji M,Yamaguchi T,Miki T,Satoh F,Takayama S,Yamasaki S,Kawaguchi K,Sato H,Ishii T,Ito S,CKOALA study group.

更新日期：2020-04-22 00:00:00

abstract：BACKGROUND:Accurately determining renal function is essential for clinical management of HIV patients. Classically, it has been evaluated by estimating glomerular filtration rate (eGFR) with the MDRD-equation, but today there is evidence that the new Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation ...

journal_title：BMC nephrology

authors： Cristelli MP,Cofán F,Rico N,Trullàs JC,Manzardo C,Agüero F,Bedini JL,Moreno A,Oppenheimer F,Miro JM,CKD-H. Clinic Investigators.

更新日期：2017-02-10 00:00:00

abstract：BACKGROUND:Chronic cyclosporine-(CsA)-mediated loss of kidney function is a major clinical problem in organ transplantation. We hypothesized that the mineralocorticoid receptor antagonist eplerenone (EPL) prevents chronic CsA-induced renal interstitial volume increase, tubule loss, and functional impairment in a rat mo...

journal_title：BMC nephrology

authors： Nielsen FT,Jensen BL,Hansen PB,Marcussen N,Bie P

更新日期：2013-02-20 00:00:00

abstract：BACKGROUND:Emerging evidence of psychosocial problems in CKD patients has led to an acceptance that a focus on the emotional wellbeing of the patient should be included in the provision of comprehensive CKD care. It is unclear if an increased attention for psychosocial needs in guidelines and policy documents has led t...

journal_title：BMC nephrology

authors： Seekles ML,Ormandy P,Coyne E

更新日期：2019-03-21 00:00:00

abstract：BACKGROUND:Indoleamine 2, 3-dioxygenase (IDO) is an immunomodulatory molecule that has been implicated in several biological processes. Although IDO has been linked with some renal diseases, its role in renal fibrosis is still unclear. Because IDO may be modulated by TGF-β1, a potent fibrogenic molecule, we hypothesize...

journal_title：BMC nephrology

authors： Matheus LHG,Simão GM,Amaral TA,Brito RBO,Malta CS,Matos YST,Santana AC,Rodrigues GGC,Albejante MC,Bach EE,Dalboni MA,Camacho CP,Dellê H

更新日期：2017-09-06 00:00:00

abstract：BACKGROUND:Alport syndrome and ANCA-associated vasculitis are both rare diseases. The co-existence of these two conditions has never been reported. There is no obvious pathogenic link between these two glomerular diseases. The management of this case highlights the importance of a systematic approach when investigating...

journal_title：BMC nephrology

authors： Gillion V,Jadoul M,Aydin S,Godefroid N

更新日期：2017-03-29 00:00:00

abstract：BACKGROUND:Health-Related Quality of Life (HRQoL) assessment after kidney transplantation has become an important tool in evaluating outcomes. This study aims to identify the associated factors with HRQoL among a representative sample size of Kidney Transplant Recipients (KTR) at the time of their inclusion in the stud...

journal_title：BMC nephrology

authors： Mouelhi Y,Jouve E,Alessandrini M,Pedinielli N,Moal V,Meurette A,Cassuto E,Mourad G,Durrbach A,Dussol B,Gentile S

更新日期：2018-04-27 00:00:00

abstract：BACKGROUND:Epithelioid angiomyolipoma is defined as potentially malignant mesenchymal neoplasm, characterized by proliferating epithelioid cells, whereas classic angiomyolipoma, composed of fat, smooth muscle cells and dysmorphic vessels, is defined as a potentially benign. The usual or classic angiomyolipoma is often ...

journal_title：BMC nephrology

authors： Tuma J,Moch H,Stuckmann G,Gysel W,Serra AL

更新日期：2018-05-30 00:00:00

abstract：BACKGROUND:The risk of an individual to develop an acute kidney injury (AKI), or its severity, cannot be reliably predicted by common clinical risk factors. Whether genetic risk factors have an explanatory role poses an interesting question, however. Thus, we conducted a systematic literature review regarding genetic p...

journal_title：BMC nephrology

authors： Vilander LM,Kaunisto MA,Pettilä V

更新日期：2015-12-02 00:00:00

abstract：BACKGROUND:Interleukin 17 is a proinflammatory cytokine involved in immune response after allograft transplantation. IL-17 family of proinflammatory cytokines includes IL-17A and IL-17F. Previous studies have demonstrated that the rs2275913 IL17A and the rs11465553 IL17F gene polymorphism are associated with kidney all...

journal_title：BMC nephrology

authors： Domanski L,Kłoda K,Patrzyk M,Wisniewska M,Safranow K,Sienko J,Sulikowski T,Staniszewska M,Pawlik A

更新日期：2019-04-08 00:00:00

abstract：BACKGROUND:Fibrillary glomerulonephritis (FGN) is distinguished from amyloidosis by thicker fibrils and the lack of staining with histochemical dyes typically reactive with amyloid. However, congophilic FGN has been proposed recently and adding laser microdissection followed by mass spectrometry (LMD/MS) to conventiona...

journal_title：BMC nephrology

authors： Adachi M,Kitamura M,Muta K,Maekawa A,Uramatsu T,Tadokoro M,Funakoshi S,Hisano S,Kuwahara N,Shimizu A,Mukae H,Nishino T

更新日期：2020-05-24 00:00:00

abstract：BACKGROUND:Lower serum bicarbonate, mainly due to the modern Western-style diet, and renal hyperfiltration (RHF) are both independently associated with higher mortality in the general population with preserved renal function. The objective of this study was to evaluate the association between serum bicarbonate and RHF....

journal_title：BMC nephrology

authors： Park M,So R,Joo KW,Yoon HJ

更新日期：2016-01-06 00:00:00

abstract：BACKGROUND:The KDIGO Clinical Practice Guidelines for Glomerulonephritis recommended tacrolimus as an alternative regimen for the initial therapy for Idiopathic membranous nephropathy (IMN), however, large observational studies evaluating tacrolimus treatment in IMN remains rare. METHODS:A total of 408 consecutive IMN...

journal_title：BMC nephrology

authors： Qin HZ,Liu L,Liang SS,Shi JS,Zheng CX,Hou Q,Lu YH,Le WB

更新日期：2017-01-05 00:00:00