Abstract:
BACKGROUND:The European Organization for Research and Treatment of Cancer QOL Core Questionnaire 30 (EORTC QLQ-30) and the Assessment of Cancer Therapy-General (FACT-G) are the two most widely used measures of cancer-specific health-related quality of life (HRQOL). This study aims to assess whether the two instruments measure the same constructs of HRQOL in patients with total laryngectomy. METHODS:The EORTC QLQ-30 and the FACT-G was completed by 132 patients with total laryngectomy. Convergent, discriminant, and construct validity of the EORTC QLQ-C30 and the FACT-G were assessed by Spearman's correlation and explanatory factor analysis. RESULTS:The results of factor analysis showed that the EORTC QLQ-C30 and the FACT-G measure different aspects of HRQOL. Moreover, both instruments showed excellent convergent and discriminant validity, except for nausea and vomiting symptom subscale in the EORTC QLQ-C30 questionnaire. The internal consistency was close or greater than 0.7 for all domains of both instruments except for functional wellbeing in FACT-G. CONCLUSIONS:This study revealed that neither of the two instruments can be replaced by the other in the assessment of HRQOL in Iranian patients with total laryngectomy. Accordingly, clinicians should exactly define their research questions related to patient-reported outcomes before choosing which instrument to use.
journal_name
Health Qual Life Outcomesjournal_title
Health and quality of life outcomesauthors
Iravani K,Jafari P,Akhlaghi A,Khademi Bdoi
10.1186/s12955-018-1012-xsubject
Has Abstractpub_date
2018-09-14 00:00:00pages
183issue
1issn
1477-7525pii
10.1186/s12955-018-1012-xjournal_volume
16pub_type
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journal_title:Health and quality of life outcomes
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journal_title:Health and quality of life outcomes
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journal_title:Health and quality of life outcomes
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journal_title:Health and quality of life outcomes
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journal_title:Health and quality of life outcomes
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journal_title:Health and quality of life outcomes
pub_type: 杂志文章
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journal_title:Health and quality of life outcomes
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journal_title:Health and quality of life outcomes
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journal_title:Health and quality of life outcomes
pub_type: 杂志文章
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abstract::. ...
journal_title:Health and quality of life outcomes
pub_type: 杂志文章,已发布勘误
doi:10.1186/s12955-019-1122-0
更新日期:2019-03-27 00:00:00
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journal_title:Health and quality of life outcomes
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doi:10.1186/1477-7525-10-132
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journal_title:Health and quality of life outcomes
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pub_type: 杂志文章,随机对照试验
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journal_title:Health and quality of life outcomes
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journal_title:Health and quality of life outcomes
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