Abstract：
OBJECTIVE:To review the current published literature on the use of procalcitonin as a diagnostic and prognostic marker in adult patients with meningitis. METHODS:We conducted a PubMed search to identify all relevant publications regarding the diagnostic and prognostic value of serum procalcitonin in patients with a known or suspected central nervous system infection. We also reviewed the bibliographies of all identified manuscripts in an attempt to identify additional relevant references. RESULTS:A significant body of evidence suggests that serum procalcitonin has a promising role and can be a useful biomarker in the assessment of patients with meningitis. CONCLUSIONS:Our literature review suggests that data on the role of Cerebrospinal Fluid (CSF) procalcitonin are limited, whereas serum procalcitonin (S⁻PCT) is probably a useful tool in the evaluation of patients with a known or suspected central nervous system infection and can help distinguish between bacterial and viral meningitis.
journal_name
J Clin Medjournal_title
Journal of clinical medicineauthors
Velissaris D,Pintea M,Pantzaris N,Spatha E,Karamouzos V,Pierrakos C,Karanikolas Mdoi
10.3390/jcm7060148subject
Has Abstractpub_date
2018-06-11 00:00:00issue
6issn
2077-0383pii
jcm7060148journal_volume
7pub_type
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