Abstract:
BACKGROUND:Understanding the types of strains and lineages of Mycobacterium tuberculosis (M. tuberculosis) circulating in a country is of paramount importance for tuberculosis (TB) control program of that country. The main aim of this study was to review and compile the results of studies conducted on strains and lineages of M. tuberculosis in Ethiopia. METHODS:A systematic search and review of articles published on M. tuberculosis strains and lineages in Ethiopia were made. PubMed and Google Scholar databases were considered for the search while the keywords used were M. tuberculosis, molecular epidemiology, molecular typing spoligotyping and Ethiopia. RESULT:Twenty-one studies were considered in this review and a total of 3071 M. tuberculosis isolates and 3067 strains were included. These studies used spoligotyping and identified five lineages including Indo-Ocean, East Asian/Beijing, East African-Indian, Euro-American and Ethiopian in a proportion of 7.1%, 0.2%, 23.0%, 64.8%, and 4.1%, respectively. Thus, Euro-American was the most frequently (64.8%) occurring Lineage while East Asian was the least (0.2%) frequently occurring Lineage in the country. Surprisingly, the Ethiopian Lineage seemed to be localized to northeastern Ethiopia. In addition, the top five clades identified by this review were T, CAS, H, Manu and Ethiopian comprising of 48.0%, 23.0%, 11.0%, 6.0% and 4.1% of the strains, respectively. Furthermore, predominant shared types (spoligotype patterns) identified were SIT149, SIT53, SIT25, SIT37, and SIT21, each consisting of 420, 343, 266, 162 and 102 isolates, respectively, while, on the other hand, 15% of the strains were orphan. CONCLUSION:According to the summary of the results of this review, diversified strains and lineages of M. tuberculosis were found in Ethiopia, and the frequencies of occurrence of these strains and lineages were variable in different regions of the country. This systematic review is registered in the PRISMA with the registration number of 42017059263.
journal_name
BMC Infect Disjournal_title
BMC infectious diseasesauthors
Tulu B,Ameni Gdoi
10.1186/s12879-018-3046-4subject
Has Abstractpub_date
2018-03-27 00:00:00pages
140issue
1issn
1471-2334pii
10.1186/s12879-018-3046-4journal_volume
18pub_type
杂志文章,评审abstract:BACKGROUND:Members of Shewanella species are opportunistic pathogens that are found in marine environments. Currently more than sixty species have been identified, whereas the most commonly clinical cases associated with Shewanella species have involved only two species, i.e., S. algae and S. putrefaciens. We present t...
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journal_title:BMC infectious diseases
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pub_type: 杂志文章
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pub_type: 杂志文章
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pub_type: 临床试验,杂志文章,多中心研究
doi:10.1186/s12879-015-0963-3
更新日期:2015-06-12 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:2010-09-10 00:00:00
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pub_type: 杂志文章
doi:10.1186/1471-2334-13-63
更新日期:2013-02-02 00:00:00
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pub_type: 杂志文章
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更新日期:2014-10-18 00:00:00
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pub_type: 杂志文章,meta分析
doi:10.1186/s12879-019-4156-3
更新日期:2019-06-17 00:00:00
abstract:BACKGROUND:Dengue virus (DENV) infection is an emerging arboviral infection in tropical and sub-tropical countries in South-East Asia, the Western Pacific and South and Central America. Secondary DENV infection is the most widely accepted risk factor for the development of severe forms. Methods to discriminate primary ...
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pub_type: 杂志文章
doi:10.1186/s12879-015-1022-9
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journal_title:BMC infectious diseases
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
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pub_type: 杂志文章,多中心研究
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更新日期:2010-07-20 00:00:00
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pub_type: 杂志文章
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更新日期:2012-11-14 00:00:00
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pub_type: 杂志文章
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更新日期:2016-08-15 00:00:00
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journal_title:BMC infectious diseases
pub_type: 杂志文章
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更新日期:2018-12-04 00:00:00
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