The safety of live-attenuated vaccines in patients using IL-1 or IL-6 blockade: an international survey.

abstract：BACKGROUND:There is a critical shortage of pediatric rheumatologists in the US. Substantial travel to clinics can impose time and monetary burdens on families. The aim of this study was to evaluate the cost of in-person pediatric rheumatology visits for families and determine if telemedicine clinics resulted in time an...

journal_title：Pediatric rheumatology online journal

authors： Kessler EA,Sherman AK,Becker ML

更新日期：2016-09-20 00:00:00

abstract：: Xanthomatous skin lesions and arthritis in children are not a common association. We present the case of a 3 year old girl who presented with xanthomatous lesions in the periungual region of both hands, around the nares and on her forehead, associated with significant arthritis that was clinically compatible with mul...

journal_title：Pediatric rheumatology online journal

authors： Matiz C,Ferguson PJ,Zaenglein A,Groh B,Bingham CA

更新日期：2009-10-08 00:00:00

abstract：:Following publication of the original article [1], we have been notified that the colour representation of the graph is not correct in Figure 6 legend. ...

journal_title：Pediatric rheumatology online journal

authors： Lee WF,Wu CY,Yang HY,Lee WI,Chen LC,Ou LS,Huang JL

更新日期：2020-02-18 00:00:00

abstract：BACKGROUND:Idiopathic juvenile osteoporosis (IJO) is a rare condition of poorly understood etiology and pathophysiology that affects otherwise healthy children. This condition is characterized clinically by bone pain and vertebral fractures; spontaneous recovery is observed after puberty in the majority of cases. Altho...

journal_title：Pediatric rheumatology online journal

authors： Bacchetta J,Wesseling-Perry K,Gilsanz V,Gales B,Pereira RC,Salusky IB

更新日期：2013-02-19 00:00:00

abstract：BACKGROUND:Juvenile dermatomyositis (JDM) is the most common inflammatory myopathy in childhood and a major cause of morbidity among children with pediatric rheumatic diseases. The management of JDM is very heterogeneous. The JDM working group of the Society for Pediatric Rheumatology (GKJR) aims to define consensus- a...

journal_title：Pediatric rheumatology online journal

authors： Hinze CH,Oommen PT,Dressler F,Urban A,Weller-Heinemann F,Speth F,Lainka E,Brunner J,Fesq H,Foell D,Müller-Felber W,Neudorf U,Rietschel C,Schwarz T,Schara U,Haas JP

更新日期：2018-06-25 00:00:00

abstract：BACKGROUND:The usefulness of musculoskeletal ultrasonography (MSUS) in paediatric population is limited by lack of reference values. One of such parameters is hip joint capsule thickness, postulated as an early measure for synovitis. However, the joint capsule is hardly a distinguished structure from slit synovial cavi...

journal_title：Pediatric rheumatology online journal

authors： Żuber Z,Owczarek A,Sobczyk M,Migas-Majoch A,Turowska-Heydel D,Sternal A,Michalczak J,Chudek J

更新日期：2017-01-31 00:00:00

abstract：BACKGROUND:Kawasaki disease (KD) is the most common pediatric systemic vasculitides of unknown etiology. Recent clinical studies led to reappraisal of the usefulness of initial combination therapy of intravenous immunoglobulin (IVIG) plus a corticosteroid for patients with severe KD. However, the molecular mechanisms u...

journal_title：Pediatric rheumatology online journal

authors： Inoue T,Murakami S,Matsumoto K,Matsuda A

更新日期：2020-10-06 00:00:00

abstract：BACKGROUND:No standard treatment protocol exists for Kawasaki disease (KD) after spontaneous defervescence that does not use intravenous immunoglobulin (IVIG). Moreover, some cases present an indolent course and later develop coronary artery lesions (CALs). We aimed herein to assess the short-term prognosis of KD after...

journal_title：Pediatric rheumatology online journal

authors： Takahashi T,Sakakibara H,Morikawa Y,Miura M

更新日期：2015-11-04 00:00:00

abstract：BACKGROUND:Familial chilblain lupus (FCL) is a rare, chronic form of cutaneous lupus erythematosus, which is characterized by painful bluish-red inflammatory cutaneous lesions in acral locations. Mutations in TREX1, SAMHD1 and STING have been described in FCL patients. Less than 10 TREX1 mutation positive FCL families ...

journal_title：Pediatric rheumatology online journal

authors： Yi C,Li Q,Xiao J

更新日期：2020-04-15 00:00:00

abstract：BACKGROUND:Temporomandibular joint (TMJ) arthritis and involvement is commonly seen in Juvenile Idiopathic Arthritis (JIA). Therapy includes conservative measures, but also includes intraarticular corticosteroid injections (IASI) and systemic immunosuppressive therapy. Despite aggressive medical therapy, some patients ...

journal_title：Pediatric rheumatology online journal

authors： Lypka M,Shah K,Jones J

更新日期：2020-09-04 00:00:00

abstract：:In the following a brief commentary is given on a new European project that aims to provide the European countries with recommendations for the care of children and yound adults with rheumatic diseases. These recommendations will be based on surveys sent to PRINTO members and systematic literature reviews. Surveys on ...

journal_title：Pediatric rheumatology online journal

authors： Wulffraat NM,Vastert B,SHARE consortium.

更新日期：2013-02-15 00:00:00

abstract：BACKGROUND:Patient recruitment can be very challenging in paediatric studies, especially in relatively uncommon conditions, such as juvenile idiopathic arthritis (JIA). However, involving children and young people (CYP) in the design of such trials could promise a more rapid trajectory towards making evidence-based tre...

journal_title：Pediatric rheumatology online journal

authors： Sherratt FC,Roper L,Stones SR,McErlane F,Peak M,Beresford MW,Foster H,Ramanan AV,Rooney M,Baildam E,Young B

更新日期：2018-12-04 00:00:00

abstract：BACKGROUND:Juvenile Idiopathic Arthritis (JIA) may cause significant impairment in health-related quality of life (HrQoL), despite effective therapies. The aim of this study was to assess HrQoL during first-year treatment in patients with new-onset polyarticular JIA, and to compare treatment strategies. METHODS:In ACU...

journal_title：Pediatric rheumatology online journal

authors： Tarkiainen M,Tynjälä P,Vähäsalo P,Kröger L,Aalto K,Lahdenne P

更新日期：2019-12-16 00:00:00

abstract：BACKGROUND:To develop and test the feasibility and initial effectiveness of the Treatment and Education Approach for Childhood-onset Lupus (TEACH) protocol, a 6-session cognitive behavioral therapy (CBT) intervention for adolescents and young adults (AYA) with childhood-onset systemic lupus erythematosus (cSLE). METHO...

journal_title：Pediatric rheumatology online journal

authors： Cunningham NR,Fussner LM,Moorman E,Avar Aydin PO,Brunner HI,Kashikar-Zuck S

更新日期：2019-02-18 00:00:00

abstract：BACKGROUND:Acquired complement deficiency can occur in the setting of autoimmune syndromes, such as systemic lupus erythematosus (SLE), with very low or, occasionally, undetectable C3 levels. Based on inherited complement defects, patients with transiently low complement may be at similar risk for serious bacterial inf...

journal_title：Pediatric rheumatology online journal

authors： Al-Shaikhly T,Hayward K,Basiaga ML,Allenspach EJ

更新日期：2020-09-24 00:00:00

abstract：BACKGROUND:Recently preliminary ultrasonography (US) definitions, in B mode, for normal components of pediatric joints have been developed by the OMERACT US group. The aim of the current study was to include Doppler findings in the evaluation and definition of normal joint features that can be visualized in healthy chi...

journal_title：Pediatric rheumatology online journal

authors： Collado P,Windschall D,Vojinovic J,Magni-Manzoni S,Balint P,Bruyn GAW,Hernandez-Diaz C,Nieto JC,Ravagnani V,Tzaribachev N,Iagnocco A,D'Agostino MA,Naredo E,OMERACT ultrasound subtask force on pediatric.

更新日期：2018-04-10 00:00:00

abstract：BACKGROUND:Early diagnosis and treatment of Juvenile Idiopathic Arthritis (JIA) is essential to optimize outcomes. Wait times (WTs) to consultation with a pediatric rheumatologist consultation is a Canadian quality measure, with benchmarks set at 7 days for systemic JIA (sJIA) and 4 weeks for other JIA categories. In t...

journal_title：Pediatric rheumatology online journal

authors： Barber CEH,Barnabe C,Benseler S,Chin R,Johnson N,Luca N,Miettunen P,Twilt M,Veeramreddy D,Shiff NJ,Schmeling H

更新日期：2020-03-06 00:00:00

abstract：: Takayasu arteritis (TA) is a rare chronic inflammatory disease of the aorta and its major branches. It is seen predominantly in females during the second and third decades of life, although it can occur in childhood. The aetiology of TA remains unknown. To date, familial cases of TA have been considered rare; however...

journal_title：Pediatric rheumatology online journal

authors： Morishita KA,Rosendahl K,Brogan PA

更新日期：2011-02-02 00:00:00

abstract：PURPOSE:We investigated the etiology of acute hepatitis in three children with systemic Juvenile Idiopathic Arthritis (sJIA) taking Interleukin-1 receptor antagonist (IL1RA). METHODS:Laboratory and clinical data for three children with sJIA diagnosed at ages 13 months to 8 years who developed acute hepatitis during tr...

journal_title：Pediatric rheumatology online journal

authors： Canna S,Frankovich J,Higgins G,Narkewicz MR,Nash SR,Hollister JR,Soep JB,Dragone LL

更新日期：2009-12-22 00:00:00

abstract：:In 2018, an international Task Force formulated recommendations for treating Juvenile Idiopathic Arthritis (JIA) to target. The Task Force has not yet resolved three issues. The first issue is the lack of a single "best" target. The Task Force decided not to recommend the use of a specific instrument to assess inactiv...

journal_title：Pediatric rheumatology online journal

authors： Schoemaker CG,Swart JF,Wulffraat NM

更新日期：2020-04-16 00:00:00

abstract：OBJECTIVE:To follow up the refractory juvenile dermatomyositis (JDM) with autologous hematopoietic stem cell transplantation (AHSCT) in a long time and to investigate whether AHSCT is effective and safe to treat refractory JDM. METHODS:We collected the AHSCT and follow-up data of three patients with refractory JDM who...

journal_title：Pediatric rheumatology online journal

authors： Zhu J,Su G,Lai J,Dong B,Kang M,Li S,Zhou Z,Wu F

更新日期：2018-11-20 00:00:00

abstract：BACKGROUND:Juvenile idiopathic arthritis (JIA) is an autoimmune disease characterized by persistent chronic arthritis. Disease risk is believed to be influenced by both genetic and environmental factors. It is well established that the PTPN22 single nucleotide polymorphism (SNP) rs2476601 is associated with JIA suscept...

journal_title：Pediatric rheumatology online journal

authors： Goulielmos GN,Chiaroni-Clarke RC,Dimopoulou DG,Zervou MI,Trachana M,Pratsidou-Gertsi P,Garyfallos A,Ellis JA

更新日期：2016-04-23 00:00:00

abstract：BACKGROUND:Deficiency of interleukin-36 receptor antagonist (DITRA) is a life threatening monogenic autoinflammatory disease caused by loss of function mutations in the IL36RN gene. Affected patients develop recurrent episodes of generalized pustular psoriasis (GPP) with systemic inflammation and fever. We here review ...

journal_title：Pediatric rheumatology online journal

authors： Hospach T,Glowatzki F,Blankenburg F,Conzelmann D,Stirnkorb C,Müllerschön CS,von den Driesch P,Köhler LM,Rohlfs M,Klein C,Hauck F

更新日期：2019-07-08 00:00:00

abstract：BACKGROUND:Currently there is no consensus agreement on the degree of enhancement in normal temporomandibular joints (TMJ) in children, which makes it difficult for clinicians to distinguish between the presence/absence of mild synovitis. Quantitative measurements of synovial and condylar enhancement may be useful addi...

journal_title：Pediatric rheumatology online journal

authors： Ma GM,Amirabadi A,Inarejos E,Tolend M,Stimec J,Moineddin R,Spiegel L,Doria AS

更新日期：2015-12-01 00:00:00

abstract：: Bullous systemic lupus erythematosus is a rare blistering condition with a distinctive combination of clinical, histological and immunopathologic features that together constitute a unique bullous disease phenotype. It is often associated with autoimmunity to type VII collagen. Here we report a child who presented wi...

journal_title：Pediatric rheumatology online journal

authors： Kumar S,Agarwal I

更新日期：2007-11-21 00:00:00

abstract：BACKGROUND:JIA-associated uveitis (JIAU) is a serious, sight-threatening disease with significant long-term complications and risk of blindness, even with improved contemporary treatments. The MIWGUC was set up in order to propose specific JIAU activity and response items and to validate their applicability for clinica...

journal_title：Pediatric rheumatology online journal

authors： Foeldvari I,Klotsche J,Simonini G,Edelsten C,Angeles-Han ST,Bangsgaard R,de Boer J,Brumm G,Torrent RB,Constantin T,DeLibero C,Diaz J,Gerloni VM,Guedes M,Heiligenhaus A,Kotaniemi K,Leinonen S,Minden K,Miranda V,Miser

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:To assess the predictors for intravenous immunoglobulin (IVIG) resistance and coronary artery lesions (CALs) in Kawasaki disease (KD). METHODS:A total of 560 KD patients were reviewed retrospectively, including 410 complete KD (cKD) and 150 incomplete KD (iKD) patients. The laboratory data were compared bet...

journal_title：Pediatric rheumatology online journal

authors： Xie T,Wang Y,Fu S,Wang W,Xie C,Zhang Y,Gong F

更新日期：2017-03-21 00:00:00

abstract：:Familial Mediterranean fever (FMF) is the most common monogenic autoinflammatory disease in Canada and is characterized by a clinical syndrome of episodic inflammatory symptoms. Traditionally, the disease is defined by autosomal recessive inheritance of MEFV gene variants, yet FMF also not uncommonly manifests in indi...

journal_title：Pediatric rheumatology online journal

authors： Westwell-Roper C,Niemietz I,Tucker LB,Brown KL

更新日期：2019-05-14 00:00:00

abstract：: Although musculoskeletal ultrasound (MSUS) has emerged as an indispensible tool among physicians involved in musculoskeletal medicine in the last two decades, only recently has it become more attractive to pediatric rheumatologists. Thereafter, the use of MSUS in pediatric rheumatology has started to increase. Yet, a...

journal_title：Pediatric rheumatology online journal

authors： Tok F,Demirkaya E,Ozçakar L

更新日期：2011-09-12 00:00:00

abstract：BACKGROUND:Due to an increased frequency of vasculitis in FMF patients, many investigators have studied MEFV mutations in patients with HSP. The aim of the study is to investigate the frequency and clinical significance of MEFV mutations in Egyptian children with Henoch-Schonlein purpura (HSP). Investigating MEFV mutat...

journal_title：Pediatric rheumatology online journal

authors： Salah S,Rizk S,Lotfy HM,El Houchi S,Marzouk H,Farag Y

更新日期：2014-09-09 00:00:00