The combined effect of Parathyroid hormone (1-34) and whole-body Vibration exercise in the treatment of OSteoporosis (PaVOS)- study protocol for a randomized controlled trial.

abstract：BACKGROUND:The ACTION study (Attention deficit hyperactivity disorder Controlled Trial Investigation Of a Non-stimulant) is a multi-center, double-blind, randomized cross-over trial of the non-stimulant medication, Atomoxetine, in children and adolescents with attention deficit hyperactivity disorder (ADHD). The primar...

journal_title：Trials

authors： Tsang TW,Kohn MR,Hermens DF,Clarke SD,Clark CR,Efron D,Cranswick N,Lamb C,Williams LM

更新日期：2011-03-13 00:00:00

abstract：BACKGROUND:In the last few years, excessive internet use and computer gaming have increased dramatically. Salience, mood modification, tolerance, withdrawal symptoms, conflict, and relapse have been defined as diagnostic criteria for internet addiction (IA) and computer addiction (CA) in the scientific community. Despi...

journal_title：Trials

authors： Jäger S,Müller KW,Ruckes C,Wittig T,Batra A,Musalek M,Mann K,Wölfling K,Beutel ME

更新日期：2012-04-27 00:00:00

abstract：BACKGROUND:Despite favourable results from past meta-analyses, some recent large trials have not found heart failure (HF) disease management programs to be beneficial. To explore reasons for this, we evaluated evidence from existing meta-analyses. METHODS:Systematic review incorporating meta-review was used. We select...

journal_title：Trials

authors： Savard LA,Thompson DR,Clark AM

更新日期：2011-08-16 00:00:00

abstract：BACKGROUND:People with decompensated cirrhosis require complex medical care and are often prescribed an intricate and frequently changing medication and lifestyle regimen. However, many patients mismanage their medications or have poor comprehension of their disease and self-management tasks. This can lead to harm, hos...

journal_title：Trials

authors： Hayward KL,Martin JH,Cottrell WN,Karmakar A,Horsfall LU,Patel PJ,Smith DD,Irvine KM,Powell EE,Valery PC

更新日期：2017-07-20 00:00:00

abstract：BACKGROUND:Clavicle fractures account for around 4% of all fractures and up to 44% of fractures of the shoulder girdle. Fractures of the middle third (or mid-shaft) account for approximately 80% of all clavicle fractures. Management of this group of fractures is often challenging and the outcome can be unsatisfactory. ...

journal_title：Trials

authors： Longo UG,Banerjee S,Barber J,Chambler A,Cobiella C,Corbett S,Crowther M,Drew S,Francis A,Lee M,Garlick N,Packham I,Pearse Y,Richards A,Roberts C,Tennent D,Tims E,Ahrens PM

更新日期：2011-02-28 00:00:00

abstract：BACKGROUND:Allergic rhinitis is one of the most common health complaints worldwide. Complementary and alternative medical approaches have been employed to relieve allergic rhinitis symptoms and to avoid the side effects of conventional medication. Acupuncture has been widely used to treat patients with allergic rhiniti...

journal_title：Trials

authors： Kim JI,Lee MS,Jung SY,Choi JY,Lee S,Ko JM,Zhao H,Zhao J,Kim AR,Shin MS,Kang KW,Jung HJ,Kim TH,Liu B,Choi SM

更新日期：2009-07-14 00:00:00

abstract：BACKGROUND:Computed tomography is widely used to diagnose acute appendicitis. Many adolescents and young adults are exposed to the associated radiation. A recent single-institution trial has reported promising results for low-dose computed tomography; however, this technique has not yet been widely adopted. LOCAT (low-...

journal_title：Trials

authors： Ahn S,LOCAT group.

更新日期：2014-01-17 00:00:00

abstract：BACKGROUND:Tetramethylpyrazine (TMP), an active ingredient in the traditional Chinese herbal medicine Rhizoma Chuanxiong, has been used clinically for the prevention and treatment of cardiovascular disease. The benefits of TMP are largely attributed to its anti-oxidative and vasodilative properties. However, the effica...

journal_title：Trials

authors： Chen Y,He W,Ouyang H,Liu C,Hong C,Wang T,Yang K,Lu W,Wang J

更新日期：2019-12-16 00:00:00

abstract：BACKGROUND:In a sham-controlled double-blind trial, we aim to establish the efficacy and safety of the local application of laser therapy in patients with diabetes, onychomycosis and risk factors for diabetes-related foot complications. Onychomycosis leads to thickened and distorted nails, which in turn lead to increas...

journal_title：Trials

authors： Nijenhuis-Rosien L,Kleefstra N,Wolfhagen MJ,Groenier KH,Bilo HJ,Landman GW

更新日期：2015-03-22 00:00:00

abstract：BACKGROUND:Under a conventional two-arm randomised trial design, participants are allocated to an intervention and participating health professionals are expected to deliver both interventions. However, health professionals often have differing levels of expertise in a skill-based interventions such as surgery or psych...

journal_title：Trials

authors： Cook JA,Elders A,Boachie C,Bassinga T,Fraser C,Altman DG,Boutron I,Ramsay CR,MacLennan GS

更新日期：2015-05-30 00:00:00

abstract：BACKGROUND:There is considerable evidence showing that injured people who are involved in a compensation process show poorer physical and mental recovery than those with similar injuries who are not involved in a compensation process. One explanation for this reduced recovery is that the legal process and the associate...

journal_title：Trials

authors： Elbers NA,Akkermans AJ,Cuijpers P,Bruinvels DJ

更新日期：2013-07-20 00:00:00

abstract：BACKGROUND:Patient and public involvement (PPI) in studies carried out by the UK Medical Research Council Clinical Trials Unit (MRC CTU) at University College London varies by research type and setting. We developed a series of case studies of PPI to document and share good practice. METHODS:We used purposive sampling...

journal_title：Trials

authors： South A,Hanley B,Gafos M,Cromarty B,Stephens R,Sturgeon K,Scott K,Cragg WJ,Tweed CD,Teera J,Vale CL

更新日期：2016-07-29 00:00:00

abstract：:Tuberculosis (TB) remains a major killer amongst the infectious diseases. Current treatment involves a four-drug regimen for at least 6 months. New drugs and regimens are required to shorten treatment duration, reduce toxicity and combat drug resistance, but the optimal methodology to define the critical path for nove...

journal_title：Trials

authors： Bonnett LJ,Davies GR

更新日期：2015-11-14 00:00:00

abstract：BACKGROUND:Equine-assisted therapy is more often practiced with children and adolescents than with the elderly, although individuals in the second half of life could also profit from it. This group, from the age of 50, is characterised by increasing emotional, social, health-related and cognitive changes; a critical li...

journal_title：Trials

authors： Schmidt J,Wartenberg-Demand A,Forstmeier S

更新日期：2020-10-15 00:00:00

abstract：BACKGROUND:Increasing numbers of patients are surviving critical illness, but survival may be associated with a constellation of physical and psychological sequelae that can cause ongoing disability and reduced health-related quality of life. Limited evidence currently exists to guide the optimum structure, timing, and...

journal_title：Trials

authors： Ramsay P,Salisbury LG,Merriweather JL,Huby G,Rattray JE,Hull AM,Brett SJ,Mackenzie SJ,Murray GD,Forbes JF,Walsh TS,RECOVER trial collaboration.

更新日期：2014-01-29 00:00:00

abstract：BACKGROUND:The Pneumatic CompREssion for Preventing VENous Thromboembolism (PREVENT) trial evaluates the effect of adjunctive intermittent pneumatic compression (IPC) with pharmacologic thromboprophylaxis compared to pharmacologic thromboprophylaxis alone on venous thromboembolism (VTE) in critically ill adults. METHO...

journal_title：Trials

authors： Arabi Y,Al-Hameed F,Burns KEA,Mehta S,Alsolamy S,Almaani M,Mandourah Y,Almekhlafi GA,Al Bshabshe A,Finfer S,Alshahrani M,Khalid I,Mehta Y,Gaur A,Hawa H,Buscher H,Arshad Z,Lababidi H,Al Aithan A,Jose J,Abdukahil SA

更新日期：2018-03-15 00:00:00

abstract：BACKGROUND:Earlier vascular healing after drug-eluting stent (DES) implantation may reduce the incidence of late stent thrombosis and provide theoretical evidence to shorten dual antiplatelet therapy duration in patients with high bleeding risks. The BuMA supreme stent is a newly developed DES-coated with the sirolimus...

journal_title：Trials

authors： Li B,Jin QH,Chen YD,Wang CQ,Shi B,Su X,Fu GS,Wu YQ,Zhou XC,Yuan ZY

更新日期：2019-06-07 00:00:00

abstract：BACKGROUND:Oxygen is a life-saving, essential medicine that is important for the treatment of many common childhood conditions. Improved oxygen systems can reduce childhood pneumonia mortality substantially. However, providing oxygen to children is challenging, especially in small hospitals with weak infrastructure and...

journal_title：Trials

authors： Graham HR,Ayede AI,Bakare AA,Oyewole OB,Peel D,Gray A,McPake B,Neal E,Qazi S,Izadnegahdar R,Falade AG,Duke T

更新日期：2017-10-27 00:00:00

abstract：BACKGROUND:Dizziness is one of the most challenging symptoms in medicine. No medication for dizziness in current use has well-established curative or prophylactic value or is suitable for long-term palliative use. Unconventional remedies, such as acupuncture, should be considered and scientifically evaluated. However, ...

journal_title：Trials

authors： Xue Z,Liu CZ,Shi GX,Liu Y,Li ZX,Zhang ZH,Wang LP

更新日期：2013-12-13 00:00:00

abstract：BACKGROUND:It is expected that in 2020 more than 17,000 cases of colorectal cancer will be diagnosed in The Netherlands. To date, patients are included in a surgeon-led follow-up programme whose main focus is recurrence detection. However, patients often experience multiple physical and psychosocial problems. Currently...

journal_title：Trials

authors： Duineveld LA,Wieldraaijer T,van Asselt KM,Nugteren IC,Donkervoort SC,van de Ven AW,Smits AB,van Geloven AA,Bemelman WA,Beverdam FH,van Tets WF,Govaert MJ,Bosmans JE,Verdonck-de Leeuw IM,van Uden-Kraan CF,van Weert HC,Wind

更新日期：2015-06-26 00:00:00

abstract：BACKGROUND:Same-sex attracted young adults have been found to experience higher rates of mental health problems and greater difficulties in accessing specialist mental health care services compared to their heterosexual peers. Internet-based mental health interventions have the potential to be more engaging and accessi...

journal_title：Trials

authors： Abbott JA,Klein B,McLaren S,Austin DW,Molloy M,Meyer D,McLeod B

更新日期：2014-12-23 00:00:00

abstract：BACKGROUND:With a prevalence of 3 to 8% among women of reproductive age, severe premenstrual symptoms are very common. Symptoms range from emotional and cognitive to physical changes. Severe symptoms (that is, premenstrual syndrome) can have a strong impact on everyday functioning and quality of life. Impairment can be...

journal_title：Trials

authors： Kues JN,Janda C,Kleinstäuber M,Weise C

更新日期：2014-12-02 00:00:00

abstract：BACKGROUND:ST-elevation myocardial infarction (STEMI) accounts for nearly one third of acute coronary syndromes. Despite improved STEMI patient care, mortality remains high, contributing significantly to the ischemic heart disease burden. This may partly be related to ischemia-reperfusion injury (IRI). Remote ischemic ...

journal_title：Trials

authors： Gaspar A,Pereira MÁ,Azevedo P,Lourenço A,Marques J,Leite-Moreira A

更新日期：2015-09-08 00:00:00

abstract：BACKGROUND:Diabetes Mellitus constitutes one of the most important public health problems due to its high prevalence and enormous social and economic consequences. Diabetic foot ulcers are one of the chronic complications of diabetes mellitus and constitute the most important cause of non-traumatic amputation of inferi...

journal_title：Trials

authors： Silva SY,Rueda LC,Márquez GA,López M,Smith DJ,Calderón CA,Castillo JC,Matute J,Rueda-Clausen CF,Orduz A,Silva FA,Kampeerapappun P,Bhide M,López-Jaramillo P

更新日期：2007-09-26 00:00:00

abstract：BACKGROUND:Childhood obesity is one of the most critical public health problems in the world. It is associated with low neuromuscular function and postural deformities. Whether weight loss can improve postural stability and neuromuscular control, benefit daily activities, or prevent injury is unknown. Therefore, this s...

journal_title：Trials

authors： Sun F,Wang LJ,Wang L

更新日期：2015-04-10 00:00:00

abstract：BACKGROUND:Currently, there still is no treatment that eliminates tinnitus in all patients. Recent studies have shown that Tinnitus Retraining Therapy (TRT) significantly improves quality of life for tinnitus patients. Also, several studies have reported that transcranial Direct Current Stimulation (tDCS) has a positiv...

journal_title：Trials

authors： Rabau S,Van Rompaey V,Van de Heyning P

更新日期：2015-11-10 00:00:00

abstract：BACKGROUND:Microvascular obstruction (MVO) secondary to ischaemic-reperfusion injury is an important but underappreciated determinant of short- and longer-term outcome following percutaneous coronary intervention (PCI) treatment of ST-elevation myocardial infarction (STEMI). Several small studies have demonstrated a re...

journal_title：Trials

authors： Nazir SA,Khan JN,Mahmoud IZ,Greenwood JP,Blackman DJ,Kunadian V,Been M,Abrams KR,Wilcox R,Adgey AA,McCann GP,Gershlick AH

更新日期：2014-09-25 00:00:00

abstract：BACKGROUND:The cross-sectional area of the subclavian vein (csSCV) is an important factor determining the success rate of SCV catheterization. The head-down position increases the csSCV. However, the effects of lateral tilting on subclavian venous cross-sectional area have not yet been explored. In this trial, we test ...

journal_title：Trials

authors： Jung DE,Lee HC,Yoon HK,Park HP

更新日期：2018-05-24 00:00:00

abstract：BACKGROUND:Hearing and vision impairments are highly prevalent in people with dementia and may have a negative impact on quality of life and other dementia-related outcomes. Intervening to optimise sensory impairment and support sensory function may be a means of improving dementia-related outcomes. The SENSE-Cog trial...

journal_title：Trials

authors： Regan J,Frison E,Collin F,Dawes P,Hann M,Himmelsbach I,Hooper E,Reeves D,Simkin Z,Thodi C,Yang F,Leroi I,SENSE-Cog Trial Development Team.

更新日期：2019-01-25 00:00:00

abstract：OBJECTIVE:The objective of the Dutch Sildenafil therapy in dismal prognosis early onset fetal growth restriction (STRIDER) randomised clinical trial is to assess the beneficial and harmful effects of sildenafil versus placebo on fetal and neonatal mortality in pregnant women with severe early-onset fetal growth restric...

journal_title：Trials

authors： Pels A,Jakobsen JC,Ganzevoort W,Naaktgeboren CA,Onland W,van Wassenaer-Leemhuis AG,Gluud C

更新日期：2019-01-11 00:00:00