An evaluation of a recombinant multiepitope based antigen for detection of Toxoplasma gondii specific antibodies.

abstract：BACKGROUND:Loss to follow-up is a major challenge of antiretroviral treatment (ART) programs in sub-Saharan Africa. Our objective was to a) determine true outcomes of patients lost to follow-up (LTFU) and b) identify risk factors associated with successful tracing and deaths of patients LTFU from ART in a large public ...

journal_title：BMC infectious diseases

authors： Weigel R,Hochgesang M,Brinkhof MW,Hosseinipour MC,Boxshall M,Mhango E,Nkwazi B,Tweya H,Kamlaka M,Chagwera F,Phiri S

更新日期：2011-01-27 00:00:00

abstract：BACKGROUND:While the prevalence of multidrug-resistant (MDR) tuberculosis (TB) is high among children in the Western Cape of South Africa, the psychosocial implications of treatment for children with MDR-TB remain poorly understood. We sought to explore how MDR-TB and its treatment impact children on an individual, fam...

journal_title：BMC infectious diseases

authors： Franck C,Seddon JA,Hesseling AC,Schaaf HS,Skinner D,Reynolds L

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to prospectively investigate the value of real-time ultrasound elastography (RTE) for the diagnosis of liver fibrosis (LF) in patients with chronic hepatitis B (CHB), to correlate the elastography findings with the histologic stage of LF and to compare RTE findings with those fr...

journal_title：BMC infectious diseases

authors： Huang D,Lin T,Wang S,Cheng L,Xie L,Lu Y,Chen M,Zhu L,Shi J

更新日期：2019-10-22 00:00:00

abstract：BACKGROUND:Computer Tomography (CT) is considered the gold standard for assessing the morphological changes of lung parenchyma. Although novel CT techniques have substantially decreased the radiation dose, radiation exposure is still high. Magnetic Resonance Imaging (MRI) has been established as a radiation- free alter...

journal_title：BMC infectious diseases

authors： Rizzi EB,Schinina' V,Cristofaro M,Goletti D,Palmieri F,Bevilacqua N,Lauria FN,Girardi E,Bibbolino C

更新日期：2011-09-16 00:00:00

abstract：BACKGROUND:Pandemic influenza vaccine manufacturing capacity and distribution agility is enhanced through the availability of equivalent antigen-sparing vaccines. We evaluated equivalence in terms of immunogenicity between GlaxoSmithKline Vaccines' A/California/7/2009 (H1N1)v-like-AS03 vaccines manufactured in Dresden ...

journal_title：BMC infectious diseases

authors： Launay O,Duval X,Fitoussi S,Jilg W,Kerdpanich A,Montellano M,Schwarz TF,Watanveerade V,Wenzel JJ,Zalcman G,Bambure V,Li P,Caplanusi A,Madan A,Gillard P,Vaughn DW

更新日期：2013-09-16 00:00:00

abstract：BACKGROUND:Due to a lack of survey of health care seeking behavior for influenza, the actual magnitude of influenza in Beijing of China has not been well described. METHODS:During 2013-2014 influenza season, two cross-sectional household surveys were carried out respectively during the epidemic and non-epidemic season...

journal_title：BMC infectious diseases

authors： Wang X,Wu S,Yang P,Li H,Chu Y,Tang Y,Hua W,Zhang H,Li C,Wang Q

更新日期：2017-02-03 00:00:00

abstract：BACKGROUND:Anthrax had become extremely rare in Europe, but in 2010 an outbreak of anthrax among heroin users in Scotland increased awareness of contaminated heroin as a source of anthrax. We present the first two Danish cases of injectional anthrax and discuss the clinical presentations, which included both typical an...

journal_title：BMC infectious diseases

authors： Russell L,Pedersen M,Jensen AV,Søes LM,Hansen AB

更新日期：2013-09-03 00:00:00

abstract：BACKGROUND:Over 80% of morbidity due to soil-transmitted helminthiasis (STH) occurs in low-income countries. Children under 5 account for 20-30% of the burden in endemic areas. This study assessed the prevalence, intensity and factors associated with STH infections among preschool-age children (PSAC) in Hoima district,...

journal_title：BMC infectious diseases

authors： Ojja S,Kisaka S,Ediau M,Tuhebwe D,Kisakye AN,Halage AA,Mugambe RK,Mutyoba JN

更新日期：2018-08-17 00:00:00

abstract：BACKGROUND:It is unclear whether appropriate empiric antimicrobial therapy improves outcomes in patients with bacteremia due to Escherichia coli or Klebsiella. The objective of this study is to assess the impact of appropriate empiric antimicrobial therapy on in-hospital mortality and post-infection length of stay in p...

journal_title：BMC infectious diseases

authors： Thom KA,Schweizer ML,Osih RB,McGregor JC,Furuno JP,Perencevich EN,Harris AD

更新日期：2008-09-15 00:00:00

abstract：BACKGROUND:The increasing antimalarial drug resistance is a significant hindrance to malaria control and elimination programs. For the last six decades, chloroquine (CQ) plus pyrimethamine remains the first-line treatment for P. vivax malaria. Regions where both P. falciparum and P. vivax co-exist, P. vivax is exposed ...

journal_title：BMC infectious diseases

authors： Kaur H,Sehgal R,Kumar A,Bharti PK,Bansal D,Mohapatra PK,Mahanta J,Sultan AA

更新日期：2020-09-15 00:00:00

abstract：BACKGROUND:Hepatitis B virus (HBV) infection is a major public health burden in China although it has steadily declined over the last two decades. A valid updated prevalence of HBV infection in China relies on a large sample size. Hence this study aimed to estimate HBV seroprevalence using a large inpatient population ...

journal_title：BMC infectious diseases

authors： Meng J,Xu H,Sui D,Jiang J,Li J,Gao Y,Niu J

更新日期：2019-05-20 00:00:00

abstract：BACKGROUND:Information about improvements in the health status of population at-risk of helminth infection after anthelminthic treatment helps to evaluate the effectiveness of the large scale deworming program. The objectives of this study were to assess the impact of anthelminthic treatment on the prevalence and inten...

journal_title：BMC infectious diseases

authors： Yimam Y,Degarege A,Erko B

更新日期：2016-10-28 00:00:00

abstract：BACKGROUND:Patients with contact to healthcare-system in high-prevalence countries (HPC) and refugee patients in hospital settings (REF) have previously been identified to be at risk of carrying multidrug-resistant organisms (MDRO). Comparative studies addressing the epidemiology of MDRO in patients transferred from ho...

journal_title：BMC infectious diseases

authors： Reinheimer C,Kempf VA,Jozsa K,Wichelhaus TA,Hogardt M,O'Rourke F,Brandt C

更新日期：2017-01-05 00:00:00

abstract：BACKGROUND:Rapid diagnostic tests (RDTs) are alternative methods for microscopy in the diagnosis of malaria in resource limited settings. Among commercially available RDTs, CareStart™ Malaria test was found to show reliable results. This study evaluated the performance of CareStart™ Malaria Combo test kit in Northweste...

journal_title：BMC infectious diseases

authors： Feleke DG,Tarko S,Hadush H

更新日期：2017-06-06 00:00:00

abstract：BACKGROUND:Pneumocystis jirovecii pneumonia (PJP) can be challenging to diagnose, often requiring bronchoscopy. Since most patients suspected of PJP undergo imaging, we hypothesized that the findings of these studies could help estimate the probability of disease prior to invasive testing. METHODS:We created a cohort ...

journal_title：BMC infectious diseases

authors： Hsu JM,Hass A,Gingras MA,Chong J,Costiniuk C,Ezer N,Fraser RS,McDonald EG,Lee TC

更新日期：2020-07-10 00:00:00

abstract：BACKGROUND:The human major histocompatibility complex class I polypeptide-related sequence B (MICB) is a protein that modulates the NK and T cell activation through the NKG2D receptor and is related to several diseases including cancer. METHODS:The study investigated the prognostic role of soluble MICB (sMICB) protein...

journal_title：BMC infectious diseases

authors： Tong HV,Song le H,Hoan NX,Cuong BK,Sy BT,Son HA,Quyet D,Binh VQ,Kremsner PG,Bock CT,Velavan TP,Toan NL

更新日期：2015-01-23 00:00:00

abstract：BACKGROUND:Varicella during pregnancy can lead to serious maternal and fetal consequences. Although an effective vaccine is available it is not incorporated in to the routine vaccination programs in most of the Asian countries. Objectives of the study were to determine the susceptibility to varicella and factors associ...

journal_title：BMC infectious diseases

authors： Premathilake IP,Aluthbaduge P,Senanayake CP,Jayalatharachchi R,Gamage S,Jayamaha J

更新日期：2019-04-29 00:00:00

abstract：BACKGROUND:The steady rise in the spread of multidrug-resistant tuberculosis (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB) requires rapid and reliable methods to identify resistant strains. The current molecular methods to detect MTB resistance to second-line drugs either do not cover an extended spectr...

journal_title：BMC infectious diseases

authors： Zimenkov DV,Antonova OV,Kuz'min AV,Isaeva YD,Krylova LY,Popov SA,Zasedatelev AS,Mikhailovich VM,Gryadunov DA

更新日期：2013-05-24 00:00:00

abstract：BACKGROUND:Nosocomial infection diagnosis in the intensive care unit (ICU) remains a challenge. We compared routine measurements of procalcitonin (PCT), C-reactive protein (CRP), white blood cell count (WBC) and temperature in the detection of ICU-acquired infections. METHOD:Prospective observational cohort study in a...

journal_title：BMC infectious diseases

authors： Robriquet L,Séjourné C,Kipnis E,D'Herbomez M,Fourrier F

更新日期：2013-04-02 00:00:00

abstract：BACKGROUND:Dengue virus (DENV) infection is an emerging arboviral infection in tropical and sub-tropical countries in South-East Asia, the Western Pacific and South and Central America. Secondary DENV infection is the most widely accepted risk factor for the development of severe forms. Methods to discriminate primary ...

journal_title：BMC infectious diseases

authors： Cucunawangsih,Lugito NP,Kurniawan A

更新日期：2015-07-21 00:00:00

abstract：BACKGROUND:Bloodstream infection (BSI) due to Pseudomonas aeruginosa (Pa) has relevant clinical impact especially in relation to drug resistance determinants. The PER-1 extended-spectrum beta-lactamase (ESBL) is a common enzyme conferring high-level resistance to anti-pseudomonal cephalosporins. Risk factors and treatm...

journal_title：BMC infectious diseases

authors： Endimiani A,Luzzaro F,Pini B,Amicosante G,Rossolini GM,Toniolo AQ

更新日期：2006-03-16 00:00:00

abstract：BACKGROUND:The aim of this study was to investigate the epidemiology and resistance of methicillin-resistant Staphylococcus aureus (MRSA) isolates from long-term care facilities (LTCF) residents and to analyze the potential risk factors for MRSA occurrence, defined as MRSA colonization and/or infection. METHODS:Point ...

journal_title：BMC infectious diseases

authors： Romaniszyn D,Pobiega M,Wójkowska-Mach J,Chmielarczyk A,Gryglewska B,Adamski P,Heczko PB,Ochońska D,Bulanda M

更新日期：2014-05-18 00:00:00

abstract：BACKGROUND:Surgical site infections following coronary artery bypass graft (CABG) procedures pose substantial burden on patients and healthcare systems. This study aims to describe the incidence of surgical site infections and causative pathogens following CABG surgery over the period 2003-2012, and to identify risk fa...

journal_title：BMC infectious diseases

authors： Si D,Rajmokan M,Lakhan P,Marquess J,Coulter C,Paterson D

更新日期：2014-06-10 00:00:00

abstract：BACKGROUND:Levels of non-neutralising antibodies (AB) to the C5 domain of HIV Env gp120 are inversely related to progression of HIV infection. In this phase I/II clinical study we investigated safety of Vacc-C5, a peptide-based therapeutic vaccine candidate corresponding to C5/gp41732-744 as well as the effects on pre-...

journal_title：BMC infectious diseases

authors： Brekke K,Sommerfelt M,Ökvist M,Dyrhol-Riise AM,Kvale D

更新日期：2017-03-24 00:00:00

abstract：BACKGROUND:Intracranial infection after puncture of cerebral hematoma in patients with intracerebral hemorrhage is very common in the department of neurosurgery, yet the relevant risks remain unknown. We attempted to analyze the risk factors of intracranial infection after puncture of cerebral hematoma, to provide insi...

journal_title：BMC infectious diseases

authors： Han H,Li Y,Liu L,Liu N,Wang Y,Zhang M

更新日期：2020-12-11 00:00:00

abstract：BACKGROUND:An increased number of refractory mycoplasma pneumoniae (MP) pneumonia (MPP) cases have been reported. However the duration of MP infection in lower airway and the course of anti-MP treatment remains unclear. METHODS:We retrospectively reviewed the medical records of 94 MPP children. Patients were classifie...

journal_title：BMC infectious diseases

authors： Liu J,Zhao F,Lu J,Xu H,Liu H,Tang X,Yang H,Zhang J,Zhao S

更新日期：2019-12-10 00:00:00

abstract：BACKGROUND:Culturing has long been the gold standard for detecting aetiologic agents in bacterial infections. In some cases, however, culturing fails to detect the infection. To further investigate culture-negative samples, amplification and subsequent sequencing of the 16S rRNA gene is often applied. The aim of the pr...

journal_title：BMC infectious diseases

authors： Stavnsbjerg C,Frimodt-Møller N,Moser C,Bjarnsholt T

更新日期：2017-03-27 00:00:00

abstract：BACKGROUND:Although real-life results of sofosbuvir/simeprevir have been extensively reported from the United States, data from other geographical areas are limited. In the French observational cohort, ANRS CO22 HEPATHER, 9432 patients were given the new oral antivirals from December 2013 to June 30, 2018. We report th...

journal_title：BMC infectious diseases

authors： Laurain A,Metivier S,Haour G,Larrey D,Dorival C,Hezode C,Zoulim F,Marcellin P,Bourliere M,Zarski JP,Thabut D,Alric L,Ganne-Carrie N,Cales P,Bronowicki JP,Riachi G,Geist C,Causse X,Abergel A,Chazouilleres O,Mathuri

更新日期：2019-04-02 00:00:00

abstract：BACKGROUND:Direct immunofluorescence assays (DFA) are a rapid and inexpensive method for the detection of respiratory viruses and may therefore be used for surveillance. Few epidemiological studies have been published based solely on DFA and none included respiratory picornaviruses and human metapneumovirus (hMPV). We ...

journal_title：BMC infectious diseases

authors： Sadeghi CD,Aebi C,Gorgievski-Hrisoho M,Mühlemann K,Barbani MT

更新日期：2011-02-07 00:00:00

abstract：BACKGROUND:The spread of airborne infectious diseases such as measles is a critical public health concern. The U.S. was certified measles-free in 2000, but the number of measles cases has increased in recent years breaking the record of the nationwide annual number of cases since 1992. Although the characteristics of s...

journal_title：BMC infectious diseases

authors： Azimi P,Keshavarz Z,Cedeno Laurent JG,Allen JG

更新日期：2020-07-11 00:00:00