Abstract:
OBJECTIVE:Although chronic non-bacterial osteitis (CNO) is an ever-increasingly recognised illness in the paediatric community and the adult healthcare community, a study to assess diagnosing, treatment and the psychosocial aspect of CNO from a large population pool was not available. We aimed to investigate CNO from the patient perspective. DESIGN:Health services research, patient survey. SETTING:Ludwig-Maximilians-University (LMU) Pediatric Rheumatology Department CNO Conferences held in June 2013 and June 2015. PARTICIPANTS:Using a patient survey developed by the LMU Pediatric Rheumatology Department, 105 patients from ages 5 to 63 years were assessed regarding CNO to include epidemiological data, medical history and treatment, initial symptoms, diagnostic procedures, current symptoms, associated diseases, current treating physicians, absences in school and work due to illness and the impact of illness on patient, family and friends. RESULTS:Active CNO was reported in 90% of patients present, with 73% being women and 27% being men. An overwhelming majority (70%) reported being diagnosed within 18 months of onset of symptoms; however, the initial diagnoses were wide-ranged to include malignancies in 36% to bacterial osteomyelitis in 30%, where the majority were treated with an antibiotic and/or were biopsied. When asked about the psychosocial aspect of this illness, 83% reported that non-bacterial osteitis (NBO) negatively impacted the family, 79% reported that NBO has negatively affected either school or work and 56% reported a negative impact on friendships. CONCLUSION:Delay of diagnosis, living with differential diagnoses like malignancies and finding specialists for medical care are a few examples of what leads patients into searching for more information. The negative impact on daily life including family relationships, friendships and work/school highlights a need for better psychosocial support such as guidance counselling or psychological support due to three-quarters of patients receiving no such said support.
journal_name
BMJ Openjournal_title
BMJ openauthors
Silier CCG,Greschik J,Gesell S,Grote V,Jansson AFdoi
10.1136/bmjopen-2017-017599subject
Has Abstractpub_date
2017-12-26 00:00:00pages
e017599issue
12issn
2044-6055pii
bmjopen-2017-017599journal_volume
7pub_type
杂志文章相关文献
BMJ Open文献大全abstract:INTRODUCTION:Type 2 diabetes mellitus (T2DM) is a highly prevalent chronic disease in the Spanish population. Typically, T2DM is associated with other chronic conditions. Intensive medication at the time of diagnosis has proven effective in reducing cardiovascular risk, improving glycaemic control and preventing T2DM c...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-033725
更新日期:2020-06-23 00:00:00
abstract:OBJECTIVE:To develop and validate a prediction model for identifying women at increased risk of developing gestational hypertension (GH) in Ghana. DESIGN:A prospective study. We used frequencies for descriptive analysis, χ2 test for associations and logistic regression to derive the prediction model. Discrimination wa...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2016-012670
更新日期:2017-01-16 00:00:00
abstract:OBJECTIVES:In England, many hypertensives are not detected by primary medical care. Higher detection is associated with lower premature mortality. We aimed to summarise recent evidence on detection and interventions to improve detection in order to inform policies to improve care. DESIGN:Data sources: systematic revie...
journal_title:BMJ open
pub_type: 杂志文章,评审
doi:10.1136/bmjopen-2017-019965
更新日期:2018-03-22 00:00:00
abstract:OBJECTIVES:The aim of this study was to provide recommendations to hospital owners and employee unions about developing efficient, sustainable and safe work-hour agreements. Employees at two clinics of a hospital, one a non-intensive care and the other a newborn intensive care unit (ICU), trialled 12-hour shifts on wee...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-024292
更新日期:2019-07-09 00:00:00
abstract:OBJECTIVES:Placenta or placental chorangioma could be the origin site of infantile haemangioma since they share various histochemical and genetic characteristics with placental vascular tissue. The aim of the current study was to investigate the association between chorangiomas and infantile haemangiomas in singleton a...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2016-015539
更新日期:2017-09-03 00:00:00
abstract:INTRODUCTION:Metabolic disorder and high blood pressure are common complications globally, and specifically among people living with HIV (PLHIV). Diabetes, metabolic syndrome and hypertension are major risk factors for cardiovascular diseases and their related complications. However, the burden of metabolic syndrome, d...
journal_title:BMJ open
pub_type: 杂志文章,meta分析
doi:10.1136/bmjopen-2017-016602
更新日期:2017-07-09 00:00:00
abstract:INTRODUCTION:Whether acupuncture is efficacious for patients with functional dyspepsia is still controversial. So we designed a randomised controlled trial to settle the problem. METHODS AND ANALYSIS:We designed a multicentre, two-arm, sham-controlled clinical trial. 200 participants with functional dyspepsia will be ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2013-003377
更新日期:2013-07-30 00:00:00
abstract:OBJECTIVES:To assess whether Portuguese family physicians perform preventive health services in accordance with scientific evidence, based on the recommendations of the United States Preventive Services Task Force (USPSTF). DESIGN:Cross-sectional study. SETTING:Primary healthcare, Portuguese National Health Service. ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2014-005162
更新日期:2014-05-26 00:00:00
abstract:IMPORTANCE:The Use of a Multidrug Pill In Reducing cardiovascular Events (UMPIRE) trial has shown improved adherence with the use of a polypill strategy when compared with usual medications for cardiovascular disease (CVD) prevention. To advance from efficacy to impact, we need a better understanding of why and how suc...
journal_title:BMJ open
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1136/bmjopen-2015-008018
更新日期:2015-09-30 00:00:00
abstract:OBJECTIVE:Hepatitis B reactivation (HBr) is strongly associated with rituximab therapy. Guidelines advise hepatitis B screening and use of preventive nucleoside analogue (NA) in patients at risk. In this study, we examined screening trends, post-screening interventions and outcomes in patients receiving rituximab in li...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2020-043672
更新日期:2020-12-15 00:00:00
abstract:OBJECTIVE:The aim of this study was to examine whether there is an association between grandparental care and loneliness, social isolation and/or the size of an individual's social network among community-based adults aged ≥40 years. METHODS:Cross-sectional data were drawn from a population-based sample of individuals...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-029605
更新日期:2019-12-17 00:00:00
abstract:OBJECTIVES:To determine if point-of-care (POC) glycated haemoglobin (HbA₁c) is sufficiently accurate in real-world remote settings to predict or exclude the diagnosis of diabetes based on laboratory HbA1c measurements. DESIGN:Cross-sectional study comparing POC capillary HbA₁c results with corresponding venous HbA₁c l...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2014-006277
更新日期:2015-03-12 00:00:00
abstract:OBJECTIVE:To describe help seeking behaviour from a medical doctor and antimicrobial use for common infections among rural residents of Anhui province, China. DESIGN:A cross-sectional retrospective household survey. SETTING:12 administrative villages from rural Anhui, China. PARTICIPANTS:2760 rural residents selecte...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-024856
更新日期:2019-04-11 00:00:00
abstract:OBJECTIVES:Respiratory symptoms are associated with spirometry results but more strongly with smoking history, suggesting that alterations in the lung other than those revealed by spirometry contribute to cause symptoms. Smoking may cause obstruction of peripheral airways that is poorly detected by spirometry. The slop...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2012-001488
更新日期:2012-11-27 00:00:00
abstract:OBJECTIVES:To identify and evaluate interventions aimed at increasing uptake of, or access to, physical health screening by adults with severe mental illness; to examine why interventions might work. DESIGN:Realist review. SETTING:Primary, secondary and tertiary care. RESULTS:A systematic search identified 1448 stud...
journal_title:BMJ open
pub_type: 杂志文章,评审
doi:10.1136/bmjopen-2017-019412
更新日期:2018-02-10 00:00:00
abstract:INTRODUCTION:Healthcare systems around the world are looking for solutions to the growing problem of mental disorders. RECOVER is the synonym for an evidence-based, stepped and cross-sectoral coordinated care service model for mental disorders. RECOVER implements a cross-sectoral network with managed care, comprehensiv...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-036021
更新日期:2020-05-04 00:00:00
abstract:OBJECTIVE:The development of cynicism in medicine, defined as a decline in empathy and emotional neutralisation during medical training, is a significant concern for medical educators. We sought to use online medical student discussion groups to provide insight into how cynicism in medicine is perceived, the consequenc...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-022883
更新日期:2018-10-18 00:00:00
abstract:INTRODUCTION:Fracture healing can fail in up to 10% of cases despite appropriate treatment. While lithium has been the standard treatment for bipolar disorder, it may also have a significant impact to increase bone healing in patients with long bone fractures. To translate this knowledge into clinical practice, a rando...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-031545
更新日期:2020-01-07 00:00:00
abstract:OBJECTIVES:To test the effects of a school-based prevention programme on students' smoking-related behaviour, attitudes and knowledge 6 months after implementation over 2 school-years has ended. DESIGN:Two-arm prospective cluster randomised controlled trial with a follow-up survey 6 months after end of programme imple...
journal_title:BMJ open
pub_type: 杂志文章,随机对照试验
doi:10.1136/bmjopen-2013-004422
更新日期:2014-01-21 00:00:00
abstract:OBJECTIVES:To examine the extent of primary care follow-up and mental health outcomes among women referred for ultrasound assessment of pain and/or bleeding in early pregnancy, including those whose pregnancy is found to be viable on ultrasound assessment. DESIGN:Questionnaire study with prospective follow-up. SETTIN...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2013-002595
更新日期:2013-04-11 00:00:00
abstract:OBJECTIVES:We conducted a systematic survey of the methodological literature to identify recommended approaches for how and what randomised clinical trial (RCT) authors should report on missing participant data and, on the basis of these approaches, to propose guidance for RCT authors. METHODS:We defined missing parti...
journal_title:BMJ open
pub_type: 杂志文章,评审
doi:10.1136/bmjopen-2015-008431
更新日期:2015-12-30 00:00:00
abstract:OBJECTIVES:Computer-administered cognitive-behavioural therapy (CCBT) may be a promising treatment for adolescents with depression, particularly due to its increased availability and accessibility. The feasibility of delivering a randomised controlled trial (RCT) comparing a CCBT program (Stressbusters) with an attenti...
journal_title:BMJ open
pub_type: 杂志文章,随机对照试验
doi:10.1136/bmjopen-2016-012834
更新日期:2017-01-27 00:00:00
abstract:INTRODUCTION:Personalised cancer screening aims to improve benefits, reduce harms and being more cost-effective than age-based screening. The objective of the DECIDO study is to assess the acceptability and feasibility of offering risk-based personalised breast cancer screening and its integration in regular clinical p...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2020-044597
更新日期:2020-12-23 00:00:00
abstract:OBJECTIVES:Inspired by the James Lind Alliance (JLA) user involvement approach, the aim of the present study was to identify the top 10 uncertainties for sleep research raised by students in higher education, and to discuss our experiences with adapting the JLA method to a student population. DESIGN:The study design i...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2020-043697
更新日期:2021-01-26 00:00:00
abstract:OBJECTIVES:While studies at the undergraduate level have begun to explore healthcare students' safety and dignity dilemmas, none have explored such dilemmas with multiple stakeholders at the postgraduate level. The current study therefore explores the patient and staff safety and dignity narratives of multiple stakehol...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-025615
更新日期:2019-05-27 00:00:00
abstract:OBJECTIVE:To explore how patients who are wait-listed for or who have received a kidney transplant understand the current UK kidney allocation system, and their views on ways to allocate kidneys in the future. DESIGN:Qualitative study using semistructured interviews and thematic analysis based on a pragmatic approach....
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2016-013896
更新日期:2017-01-27 00:00:00
abstract:OBJECTIVES:Evidence about the relationship between socioeconomic status (SES) and small-for-gestational-age (SGA) infants was insufficient among Chinese primiparae. In addition, factors that may mediate this relationship are poorly understood. The purpose of this study was to investigate the risk of and mediators betwe...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2017-020694
更新日期:2018-06-14 00:00:00
abstract:BACKGROUND:Since the Singapore Mental Health Study in 2010 which reported a 16.0% prevalence rate for current smokers and 4.5% for nicotine dependence, new anti-smoking strategies have been implemented. The aim of this study was to compare smoking trends from the 2010 study with the second Singapore Mental Health Study...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-032198
更新日期:2019-10-18 00:00:00
abstract:OBJECTIVES:To examine if the estimated glomerular filtration rate (eGFR) slope over a 5-year period is related to incident cardiovascular (CV) events in the following 5 years. DESIGN:Retrospective cohort study. SETTING:Primary care. PARTICIPANTS:All patients aged ≥50 years with at least four eGFR measurements betwee...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-023594
更新日期:2018-11-12 00:00:00
abstract:OBJECTIVES:To estimate the absolute cardiovascular disease (CVD) risk burden in a remote rural Bangladeshi population using the 'With' and 'Without' Cholesterol versions of the WHO/International Society of Hypertension (WHO/ISH) CVD risk assessment chart (particularly suitable for low and middle-income countries due to...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2015-008140
更新日期:2015-10-13 00:00:00