Abstract:
OBJECTIVE:To investigate sex differences in survival of primary care treated patients with type 2 diabetes (T2D) in the Netherlands. SETTING:Primary care. PARTICIPANTS:A total of 1815 patients who participated in a prospective observational cohort study (Zwolle Outpatient Diabetes Project Integrating Available Care (ZODIAC)) were included of which 56% was female. Inclusion took place in 1998, 1999 and 2001. Vital status was assessed in 2013. MAIN OUTCOME MEASURE:Relative survival of men and women with T2D. The relative survival rate was expressed as the ratio of observed survival of patients divided by the survival of the general population in the Netherlands with comparable age. RESULTS:After 14 years, 888 (49%) patients had died. The relative survival rate was 0.88 (0.81-0.94) for men and 0.82 (0.76-0.87) for women with T2D after 14 years (p value for difference between sexes=0.169). In patients without a history of cardiovascular diseases (CVD), the relative survival was 0.99 (0.94-1.05) in men and 0.92 (0.87-0.97) in women (p value for difference between sexes=0.046). CONCLUSIONS:The survival of men and women with T2D was 12% and 18% lower, respectively, after 14 years of follow-up compared with men and women in the general population. This corresponds to a decrease in median survival of 2.2 and 3.5 years in men and women, respectively. Only for patients with T2D without a history of CVD, a significantly lower relative survival in women compared with men with T2D was found.
journal_name
BMJ Openjournal_title
BMJ openauthors
Hendriks SH,van Hateren KJJ,Groenier KH,Landman GWD,Maas AHEM,Bilo HJG,Kleefstra Ndoi
10.1136/bmjopen-2017-015870subject
Has Abstractpub_date
2017-10-25 00:00:00pages
e015870issue
10issn
2044-6055pii
bmjopen-2017-015870journal_volume
7pub_type
杂志文章相关文献
BMJ Open文献大全abstract:OBJECTIVE:To develop and validate a prediction model for identifying women at increased risk of developing gestational hypertension (GH) in Ghana. DESIGN:A prospective study. We used frequencies for descriptive analysis, χ2 test for associations and logistic regression to derive the prediction model. Discrimination wa...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2016-012670
更新日期:2017-01-16 00:00:00
abstract:OBJECTIVES:Multimorbidity is the presence of 2 or more medical conditions. This increasingly used assessment has not been assessed in a surgical population. The objectives of this study were to assess the prevalence of multimorbidity and its association with common outcome measures. DESIGN:A cross-sectional observatio...
journal_title:BMJ open
pub_type: 杂志文章,多中心研究
doi:10.1136/bmjopen-2015-010126
更新日期:2016-03-31 00:00:00
abstract:OBJECTIVES:Few studies of tornado injuries have considered differences related to damage levels and Enhanced-Fujita (EF) scale ratings. This study aimed to evaluate the pattern, spectrum and geographical distribution of injuries related to the Yancheng tornado and provide guidelines for effective emergency medical stra...
journal_title:BMJ open
pub_type: 杂志文章,多中心研究
doi:10.1136/bmjopen-2018-021552
更新日期:2018-06-22 00:00:00
abstract:INTRODUCTION:Emergency department (ED) visits for epilepsy are common, costly, often clinically unnecessary and typically lead to little benefit for epilepsy management. An 'Alternative Care Pathway' (ACP) for epilepsy, which diverts people with epilepsy (PWE) away from ED when '999' is called and leads to care elsewhe...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-031696
更新日期:2019-11-02 00:00:00
abstract:OBJECTIVES:To assess acceptability and feasibility of trial processes and the Rehabilitation Training (ReTrain) intervention including an assessment of intervention fidelity. DESIGN:A two-group, assessor-blinded, randomised controlled trial with parallel mixed methods process and economic evaluations. SETTING:Communi...
journal_title:BMJ open
pub_type: 杂志文章,随机对照试验
doi:10.1136/bmjopen-2017-018409
更新日期:2018-02-15 00:00:00
abstract:OBJECTIVES:Although several rehabilitation programmes following hip arthroscopy for femoracetabular impingement (FAI) syndrome have been described, there are no clinical trials evaluating whether formal physiotherapy-prescribed rehabilitation improves recovery compared with self-directed rehabilitation. The objective o...
journal_title:BMJ open
pub_type: 杂志文章,随机对照试验
doi:10.1136/bmjopen-2016-014658
更新日期:2017-06-23 00:00:00
abstract:OBJECTIVE:To provide insight into the motives for hospital self-referral during office hours and the barriers deterring general practitioner (GP) consultation with a primary care request. SETTING:People who self-referred at a Daytime General Practice Cooperative (GPC) in two hospitals in The Hague, The Netherlands. P...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-029853
更新日期:2019-06-06 00:00:00
abstract:INTRODUCTION:The creatine kinase circuit is central to the regulation of high-energy phosphate metabolism and the maintenance of cellular energy turnover. This circuit is fuelled by creatine, an amino acid derivative that can be obtained from a diet containing animal products, and by synthesis in the body de novo. A re...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-026756
更新日期:2019-01-15 00:00:00
abstract:OBJECTIVES:To use wrist-actrigrphy to collect objective measures of sleep and to characterise actigraphy-measured sleep patterns among children with disabilities. We also assessed the extent to which, if at all, caregivers' education is associated with children's sleep disturbances. DESIGN:Cross-sectional study. SETT...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2015-008589
更新日期:2015-12-07 00:00:00
abstract::Objectives Control of the tuberculosis (TB) epidemic is a global health priority and one that is likely to be achieved only through vaccination. The critical overlap with the HIV epidemic requires any effective TB vaccine regimen to be safe in individuals who are infected with HIV. The objectives of this clinical tria...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2011-000223
更新日期:2011-11-14 00:00:00
abstract:INTRODUCTION:One potential stressor that can affect preimplantation and postimplantation embryonic growth after in vitro fertilisation (IVF) is the pH of the human embryo culture medium, but no evidence exists to indicate which pH level is optimal for IVF. Based on anecdotal evidence or mouse models, culture media manu...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-034194
更新日期:2020-02-04 00:00:00
abstract:OBJECTIVE:The Yale Global Tic Severity Scale (YGTSS) is the most commonly used clinician-rated evaluation tool for Tourette syndrome (TS), with established reliability and validity. This study aims to determine whether the YGTSS is a valid parent-reported assessment in the TS population. DESIGN:A prospective cohort st...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-034634
更新日期:2020-08-20 00:00:00
abstract:INTRODUCTION:Type 1 diabetes can be diagnosed at an early presymptomatic stage by the detection of islet autoantibodies. The Fr1da study aims to assess whether early staging of type 1 diabetes (1) is feasible at a population-based level, (2) prevents severe metabolic decompensation observed at the clinical manifestatio...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2016-011144
更新日期:2016-05-18 00:00:00
abstract:OBJECTIVE:To examine the effects of a consultant-led, community-based chronic obstructive pulmonary disease (COPD) service, based in a highly deprived area on emergency hospital admissions. DESIGN:A longitudinal matched controlled study using difference-in-differences analysis to compare the change in outcomes in the ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-032931
更新日期:2020-05-27 00:00:00
abstract:OBJECTIVE:This study evaluated knowledge, opinions and compliance related to Uganda's comprehensive smoke-free law among hospitality venues in Kampala Uganda. DESIGN:This multi-method study presents cross-sectional findings of the extent of compliance in the early phase of Uganda's comprehensive smoke-free law (2 mont...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2017-017601
更新日期:2018-01-05 00:00:00
abstract:PURPOSE:Acute-on-chronic liver failure (ACLF) is a clinical syndrome with high short-term mortality, unclear mechanism and controversial diagnosis criteria. The Chinese Acute-on-Chronic Liver Failure (CATCH-LIFE) study has been conducted in China to fill the gaps. In the first phase (the CATCH-LIFE investigation cohort...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2020-037793
更新日期:2021-01-08 00:00:00
abstract:INTRODUCTION:Personalised cancer screening aims to improve benefits, reduce harms and being more cost-effective than age-based screening. The objective of the DECIDO study is to assess the acceptability and feasibility of offering risk-based personalised breast cancer screening and its integration in regular clinical p...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2020-044597
更新日期:2020-12-23 00:00:00
abstract:INTRODUCTION:Despite the frequent use of therapies in acute bronchitis, the evidence of their benefit is lacking, since only a few clinical trials have been published, with low sample sizes, poor methodological quality and mainly in children. The objective of this study is to compare the effectiveness of three symptoma...
journal_title:BMJ open
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1136/bmjopen-2018-028159
更新日期:2019-05-16 00:00:00
abstract:INTRODUCTION:Exposure to secondhand smoke (SHS) increases children's risk of acquiring chest and ear infections, tuberculosis, meningitis and asthma. Smoking bans in public places (where implemented) have significantly reduced adults' exposure to SHS. However, for children, homes remain the most likely place for them t...
journal_title:BMJ open
pub_type: 杂志文章,随机对照试验
doi:10.1136/bmjopen-2015-008749
更新日期:2015-08-25 00:00:00
abstract:INTRODUCTION:Coping skills training interventions have been found to be efficacious in helping both patients and their partners manage the physical and emotional challenges they face following a cancer diagnosis. However, many of these interventions are costly and not sustainable. To overcome these issues, a self-direc...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2013-003337
更新日期:2013-07-24 00:00:00
abstract:OBJECTIVE AND DESIGN:We conducted a systematic review and meta-analysis to evaluate the incidence of adverse events in the emergency department (ED) during procedural sedation in the paediatric population. Randomised controlled trials and observational studies from the past 10 years were included. We adhere to the Pref...
journal_title:BMJ open
pub_type: 杂志文章,meta分析,评审
doi:10.1136/bmjopen-2016-011384
更新日期:2016-06-15 00:00:00
abstract:OBJECTIVE:The purpose of this study was to determine the current work distribution of health professionals from a public Ugandan medical school in a period of major donor funding for HIV programmes. We explore the hypothesis that programmes initiated under unprecedented health investments from the US President's Emerge...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2013-002875
更新日期:2013-05-31 00:00:00
abstract:OBJECTIVE:To examine individual, situational and organisational aspects that influence psychological impact and recovery of a patient safety incident on physicians, nurses and midwives. DESIGN:Cross-sectional, retrospective surveys of physicians, midwives and nurses. SETTING:33 Belgian hospitals. PARTICIPANTS:913 cl...
journal_title:BMJ open
pub_type: 杂志文章,多中心研究
doi:10.1136/bmjopen-2016-011403
更新日期:2016-08-31 00:00:00
abstract:OBJECTIVES:To describe low-density lipoprotein (LDL) cholesterol management and lipid-lowering treatment patterns in patients with a cardiovascular (CV) event. DESIGN:Retrospective cohort study using Clinical Practice Research Datalink records linked with Hospital Episode Statistics data. SETTING:Routine clinical pra...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2016-013851
更新日期:2017-05-10 00:00:00
abstract:INTRODUCTION:The appropriateness of using routinely collected laboratory data combined with administrative data for estimating influenza vaccine effectiveness (VE) is still being explored. This paper outlines a protocol to estimate influenza VE using linked laboratory and administrative data which could act as a compan...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-029708
更新日期:2019-09-30 00:00:00
abstract:OBJECTIVE:To investigate the relationship between short sleep and obesity among Thai adults. DESIGN:Both 4-year longitudinal and cross-sectional analyses of a large national cohort. SETTING:Thai adults residing nationwide from 2005 to 2009. PARTICIPANTS:Cohort members were enrolled as distance learners at Sukhothai ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2011-000561
更新日期:2012-02-03 00:00:00
abstract:INTRODUCTION:Smell and taste of milk are not generally considered when tube feeding preterm infants. Preterm infants have rapid growth, particularly of the brain, and high caloric needs. Enteral feeding is often poorly tolerated which may lead to growth failure and long-term neurodevelopmental impairment. Smell and tas...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-027805
更新日期:2019-07-17 00:00:00
abstract:OBJECTIVES:The primary objective was to describe Ugandan schoolgirls' menstrual hygiene management (MHM) practices and estimate the prevalence of inadequate MHM. Second, to assess the relative contribution of aspects of MHM to health, education and psychosocial outcomes. DESIGN:Secondary analysis of survey data collec...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2016-012596
更新日期:2016-12-30 00:00:00
abstract:OBJECTIVES:Taxing sugar-sweetened beverages (SSBs) is now advocated, and implemented, in many countries as a measure to reduce the purchase and consumption of sugar to tackle obesity. To date, there has been little consideration of the potential impact that such a measure could have if extended to other sweet foods, su...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2017-019788
更新日期:2018-04-26 00:00:00
abstract:INTRODUCTION:Human papillomavirus (HPV) is a causal agent of malignancies including cervical, vulvar, vaginal, penile, anal and oropharyngeal cancer, as well as benign conditions such as anogenital warts. HPV vaccination protects individuals against infections with the target HPV types and their clinical outcomes. Howe...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2020-039383
更新日期:2020-08-11 00:00:00