Abstract:
OBJECTIVES:To assess acceptability and feasibility of trial processes and the Rehabilitation Training (ReTrain) intervention including an assessment of intervention fidelity. DESIGN:A two-group, assessor-blinded, randomised controlled trial with parallel mixed methods process and economic evaluations. SETTING:Community settings across two sites in Devon. PARTICIPANTS:Eligible participants were: 18 years old or over, with a diagnosis of stroke and with self-reported mobility issues, no contraindications to physical activity, discharged from National Health Service or any other formal rehabilitation programme at least 1 month before, willing to be randomised to either control or ReTrain and attend the training venue, possessing cognitive capacity and communication ability sufficient to participate. Participants were individually randomised (1:1) via a computer-generated randomisation sequence minimised for time since stroke and level of functional disability. Only outcome assessors independent of the research team were blinded to group allocation. INTERVENTIONS:ReTrain comprised (1) an introductory one-to-one session; (2) ten, twice-weekly group classes with up to two trainers and eight clients; (3) a closing one-to-one session, followed by three drop-in sessions over the subsequent 3 months. Participants received a bespoke home-based training programme. All participants received treatment as usual. The control group received an exercise after stroke advice booklet. OUTCOME MEASURES:Candidate primary outcomes included functional mobility and physical activity. RESULTS:Forty-five participants were randomised (ReTrain=23; Control=22); data were available from 40 participants at 6 months of follow-up (ReTrain=21; Control=19) and 41 at 9 months of follow-up (ReTrain=21; Control=20). We demonstrated ability to recruit and retain participants. Participants were not burdened by the requirements of the study. We were able to calculate sample estimates for candidate primary outcomes and test procedures for process and health economic evaluations. CONCLUSIONS:All objectives were fulfilled and indicated that a definitive trial of ReTrain is feasible and acceptable. TRIAL REGISTRATION NUMBER:NCT02429180; Results.
journal_name
BMJ Openjournal_title
BMJ openauthors
Dean SG,Poltawski L,Forster A,Taylor RS,Spencer A,James M,Allison R,Stevens S,Norris M,Shepherd AI,Landa P,Pulsford RM,Hollands L,Calitri Rdoi
10.1136/bmjopen-2017-018409subject
Has Abstractpub_date
2018-02-15 00:00:00pages
e018409issue
2issn
2044-6055pii
bmjopen-2017-018409journal_volume
8pub_type
杂志文章,随机对照试验相关文献
BMJ Open文献大全abstract:INTRODUCTION:Arthroscopic surgery is a very common orthopaedic procedure. While several trials have investigated the effect of knee arthroscopy for middle-aged and older patients with meniscal tears, there is a paucity of trials comparing meniscal surgery with non-surgical treatment for younger adults. The aim of this ...
journal_title:BMJ open
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1136/bmjopen-2017-017436
更新日期:2017-08-21 00:00:00
abstract:OBJECTIVE:Frequent users of healthcare services are a vulnerable population, often socioeconomically disadvantaged, who can present multiple chronic conditions as well as mental health problems. Case management (CM) is the most frequently performed intervention to reduce healthcare use and cost. This study aimed to exa...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2016-012353
更新日期:2016-09-29 00:00:00
abstract:INTRODUCTION:An outbreak of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) was reported in Wuhan, China, in mid-December 2019, and declared a pandemic by the WHO on 11 March 2020. Due to the unknown nature of the disease and the lack of specific drugs, several potential treatments were used for patients. ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2020-039730
更新日期:2020-07-31 00:00:00
abstract:OBJECTIVE:To investigate the incidence of primary care presentations for herpes zoster (zoster) in a representative New Zealand population and to evaluate the utilisation of primary healthcare services following zoster diagnosis. DESIGN:A cross-sectional retrospective cohort study used a natural language processing so...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2017-021241
更新日期:2018-05-31 00:00:00
abstract:BACKGROUND:COVID-19 has posed several medical, psychosocial and economic impacts among the majority of the society. The ambiguity of its transmission, the intense desire of self-protection, family, and friends, the unknown impact of catching the disease itself, unstoppable spread, the panic and outright misinformation ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2020-043185
更新日期:2021-01-06 00:00:00
abstract:OBJECTIVES:To support sustainability of the welfare society enhanced work retention is needed among those with impaired work ability. Partial health-related benefits have been introduced for this target. The aim was to estimate the effects of partial sick leave on transition to disability pension applying propensity sc...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2012-001752
更新日期:2012-11-08 00:00:00
abstract:OBJECTIVE:Little is known about the potential health effects of eating organic food either in the general population or during pregnancy. The aim of this study was to examine associations between organic food consumption during pregnancy and the risk of pre-eclampsia among nulliparous Norwegian women. DESIGN:Prospecti...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2014-006143
更新日期:2014-09-10 00:00:00
abstract:OBJECTIVE:To evaluate the efficiency of county public hospitals in Shandong Province following China's new medical reform and compare the efficiency of hospitals with different bed sizes for improving efficiency. DESIGN AND SETTING:This was a cross-sectional study on the efficiency and size of 68 county public hospita...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-035703
更新日期:2020-06-15 00:00:00
abstract:INTRODUCTION:Opioid use has increased globally for the management of chronic non-cancer-related pain. There are concerns regarding the misuse of opioids leading to persistent opioid use and subsequent hospitalisation and deaths in developed countries. Hospital admissions related to surgery or trauma have been identifie...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2020-044493
更新日期:2021-01-19 00:00:00
abstract:OBJECTIVE:Lean interventions aim to improve quality of healthcare by reducing waste and facilitate flow in work processes. There is conflicting evidence on the outcomes of lean thinking, with quantitative and qualitative studies often contradicting each other. We suggest that reviewing the literature within the approac...
journal_title:BMJ open
pub_type: 杂志文章,评审
doi:10.1136/bmjopen-2013-003873
更新日期:2014-01-15 00:00:00
abstract:INTRODUCTION:Depressive disorders are very common diseases entailing a great burden on affected people. However, comprehensive information on long-term disease course in patients with severe depression is lacking so far. The objectives of the DELTA study are to examine long-term outcomes and their predicting factors, t...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-032507
更新日期:2019-12-23 00:00:00
abstract:OBJECTIVE:Most literature on length of stay (LOS) for childbirth focuses on 'early' discharge as opposed to 'optimal' time of discharge and has conflicting results due to heterogeneous definitions of 'early' discharge and differing eligibility criteria for these programmes. We aimed to determine the LOS associated with...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2016-012007
更新日期:2016-09-14 00:00:00
abstract:OBJECTIVES:To elucidate the views of intermittent catheter (IC) users regarding urinary tract infection (UTI) symptom presentation, terminology for describing signs and symptoms, the cause of UTI and management strategies. DESIGN:Qualitative study with semi-structured interviews. The transcribed text was analysed them...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2017-016453
更新日期:2017-09-03 00:00:00
abstract:OBJECTIVES:To examine the burden of comorbidity, polypharmacy and herpes zoster (HZ), an infectious disease, and its main complication post-herpetic neuralgia (PHN) in young (50-70 years of age: 70-) and old (≥ 70 years of age: 70+) patients. DESIGN:Post hoc analysis of the results of the 12-month longitudinal prospec...
journal_title:BMJ open
pub_type: 杂志文章,多中心研究
doi:10.1136/bmjopen-2015-009689
更新日期:2016-02-18 00:00:00
abstract:OBJECTIVES:To identify emergency seizure admissions to hospital and their subsequent access to specialist outpatient services. DESIGN:Algorithmic analysis of anonymised routine hospital data over 7 years using specialist follow-up by 3 months as the target outcome. POPULATION:All adults resident in Merseyside and Che...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2015-010100
更新日期:2016-01-20 00:00:00
abstract:INTRODUCTION:Type 2 diabetes (T2D) is a significant problem, and lifestyle modifications including self-management are important. We have developed a structured individual-based lifestyle education (SILE) programme for T2D. With attention now being paid to techniques to change behaviour, we recently developed a behavio...
journal_title:BMJ open
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1136/bmjopen-2017-017838
更新日期:2017-10-24 00:00:00
abstract:INTRODUCTION:Robot-assisted laparoscopic prostatectomy (RALP) offers potential cure for localised prostate cancer but is associated with considerable toxicity. Potency and urinary continence are improved when the neurovascular bundles (NVBs) are spared during a nerve spare (NS) RALP. There is reluctance, however, to pe...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-028132
更新日期:2019-06-11 00:00:00
abstract:PURPOSE:The ChicagO Multiethnic Prevention and Surveillance Study or 'COMPASS' is a population-based cohort study with a goal to examine the risk and determinants of cancer and chronic disease. COMPASS aims to address factors causing and/or exacerbating health disparities using a precision health approach by recruiting...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2020-038481
更新日期:2020-09-16 00:00:00
abstract:OBJECTIVES:Prevalence estimates of multimorbidity vary widely due to inconsistent definitions and measurement methods. This study examines the independent effects on prevalence estimates of how 'disease entity' is defined-as a single chronic condition or chapters/domains in the International Classification of Primary C...
journal_title:BMJ open
pub_type: 杂志文章,多中心研究
doi:10.1136/bmjopen-2013-004694
更新日期:2014-07-11 00:00:00
abstract:OBJECTIVES:This study sought to explore patients' experiences of living with, and adapting to, chronic obstructive pulmonary disease (COPD) in the rural context. Specifically, our research question was 'What are the barriers and facilitators to living with and adapting to COPD in rural Australia?' DESIGN:Qualitative, ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-030953
更新日期:2019-10-07 00:00:00
abstract:OBJECTIVES:Identification of rehospitalisations for heart failure and contributing factors flags health policy intervention opportunities designed to deliver care at a most effective and efficient level. Recognising that heart failure is a condition for which timely and appropriate outpatient care can potentially preve...
journal_title:BMJ open
pub_type: 杂志文章,多中心研究
doi:10.1136/bmjopen-2019-031346
更新日期:2019-09-03 00:00:00
abstract:OBJECTIVE:Hispanics/Latinos, the largest immigrant population in the USA, undergo the process of acculturation and have a large burden of heart failure risk. Few studies have examined the association of acculturation on cardiac structure and function. DESIGN:Cross-sectional. SETTING:The Echocardiographic Study of Lat...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-028729
更新日期:2019-11-28 00:00:00
abstract:INTRODUCTION:Clown intervention may playing an important complementary role in paediatric care and recovery. However, data on its utility for symptom cluster management of hospitalised children and adolescents in acute and chronic disorders are yet to be critically evaluated. As clinicians strive to minimise the psycho...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-026524
更新日期:2019-01-21 00:00:00
abstract:INTRODUCTION:Osteoarthritis of the knee has been identified as the most common disability in Pakistan. Total knee replacement (TKR) surgery is the curative treatment for advanced osteoarthritis of the knee; however, cost remains one of the barriers to effective and timely service delivery. OBJECTIVE:We conducted a tim...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-025258
更新日期:2019-05-28 00:00:00
abstract:OBJECTIVES:Despite the increasing number of interventions aiming to integrate cervical cancer screening into HIV clinics in sub-Saharan Africa, Women living with HIV (WLHIV) still have a high risk of developing cervical cancer. The aim of this study was to estimate the coverage of cervical cancer screening and associat...
journal_title:BMJ open
pub_type: 杂志文章,多中心研究
doi:10.1136/bmjopen-2019-029882
更新日期:2019-08-30 00:00:00
abstract:OBJECTIVES:There currently exists no reliable or validated tool for the assessment of exercise-related injuries in older adults. The purpose was to develop and evaluate the psychometric properties of a questionnaire to measure exercise-related injury in older adults participating in supervised exercise programmes. DES...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2012-001777
更新日期:2012-11-22 00:00:00
abstract:OBJECTIVE:To measure poverty-based disparities in inpatient length of stay for paediatric hospitalisations. In particular, this paper examines the relationship between municipality level poverty rates and length of stay, accounting for individual level characteristics. DESIGN:We use patient discharge data to conduct a...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-034512
更新日期:2020-08-16 00:00:00
abstract:INTRODUCTION:Premature infants are particularly vulnerable to brain injuries with associated cognitive and behavioural deficits. The worldwide first randomised interventional multicentre trial investigating the neuroprotective effects of erythropoietin (entitled 'Does erythropoietin improve outcome in very preterm infa...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-022157
更新日期:2018-04-24 00:00:00
abstract:INTRODUCTION:Patients presenting with acute intracerebral haemorrhage are at a high risk of exhibiting haematoma expansion, a phenomenon that can significantly worsen long-term functioning. Numerous clinical and radiological factors are associated with expansion. In a bid to better select patients at increased risk of ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-024744
更新日期:2019-01-21 00:00:00
abstract:BACKGROUND:Delirium is common among seniors discharged from the emergency department (ED) and associated with increased risk of mortality. Prior research has addressed mortality associated with seniors discharged from the ED with delirium, however has generally relied on data from one or a small number of institutions ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2017-021258
更新日期:2018-05-05 00:00:00