Assessment of free radical scavenging and anti-proliferative activities of Tinospora cordifolia Miers (Willd).

abstract：BACKGROUND:Traditional Chinese medicine (TCM) has been used to treat chronic obstructive pulmonary disease (COPD) for many years. This study aimed to evaluate the efficacy and safety of the comprehensive therapy based on the three common TCM patterns in stable COPD patients. METHODS:A four-center, open-label randomize...

journal_title：BMC complementary and alternative medicine

authors： Li SY,Li JS,Wang MH,Xie Y,Yu XQ,Sun ZK,Ma LJ,Zhang W,Zhang HL,Cao F,Pan YC

更新日期：2012-10-29 00:00:00

abstract：BACKGROUND:Exposure to carbon black nanoparticles (CBNPs), a well-known industrial production, promotes pulmonary toxicity through inflammation and oxidative stress. Recent studies show that some polyphenols exert their antioxidant properties through regulation of protein kinase C-α (PKC-α) and NADPH oxidase (Nox) sign...

journal_title：BMC complementary and alternative medicine

authors： Hsu HT,Tseng YT,Wong WJ,Liu CM,Lo YC

更新日期：2018-07-09 00:00:00

abstract：BACKGROUND:Samsoeum (SSE), a traditional herbal formula, has been widely used to treat cough, fever, congestion, and emesis for centuries. Recent studies have demonstrated that SSE retains potent pharmacological efficiency in anti-allergic and anti-inflammatory reactions. However, the anti-cancer activity of SSE and it...

journal_title：BMC complementary and alternative medicine

authors： Kim A,Yim NH,Ma JY

更新日期：2013-09-23 00:00:00

abstract：BACKGROUND:Mitochondrial dysfunction and oxidative stress are the main toxic events leading to dopaminergic neuronal death in Parkinson's disease (PD) and identified as vital objective for therapeutic intercession. This study investigated the neuro-protective effects of the demethoxycurcumin (DMC), a derivative of curc...

journal_title：BMC complementary and alternative medicine

authors： Ramkumar M,Rajasankar S,Gobi VV,Dhanalakshmi C,Manivasagam T,Justin Thenmozhi A,Essa MM,Kalandar A,Chidambaram R

更新日期：2017-04-18 00:00:00

abstract：BACKGROUND:Type 2 diabetes is a major health problem in many countries including India. Yoga may be an effective type 2 diabetes prevention strategy in India, particularly given its cultural familiarity. METHODS:This was a parallel, randomized controlled pilot study to collect feasibility and preliminary efficacy data...

journal_title：BMC complementary and alternative medicine

authors： McDermott KA,Rao MR,Nagarathna R,Murphy EJ,Burke A,Nagendra RH,Hecht FM

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Radiotherapy is of critical importance in the treatment of breast cancer. However, not all patients derive therapeutic benefit and some breast cancers are resistant to the treatment, and are thus evidenced with prospective distant metastatic spread and local recurrence. In this study, we investigated the pot...

journal_title：BMC complementary and alternative medicine

authors： Yan Y,Li Z,Xu X,Chen C,Wei W,Fan M,Chen X,Li JJ,Wang Y,Huang J

更新日期：2016-03-31 00:00:00

abstract：BACKGROUND:An alarm increase the rate of emerging and re-emerging of multidrug resistant bacteria have been caused great public health concern in the worldwide. They have been resisting for most or majority of currently available and affordable antibiotics and imposed socioeconomic catastrophe at global scale. As a res...

journal_title：BMC complementary and alternative medicine

authors： Gadisa E,Weldearegay G,Desta K,Tsegaye G,Hailu S,Jote K,Takele A

更新日期：2019-01-18 00:00:00

abstract：BACKGROUND:Saliva is fundamental to our oral health and our well-being. Many factors can impair saliva secretion, such as adverse effects of prescribed medication, auto-immune diseases (for example Sjögren's syndrome) and radiotherapy for head and neck cancers. Several studies have suggested a positive effect of acupun...

journal_title：BMC complementary and alternative medicine

authors： Assy Z,Brand HS

更新日期：2018-02-13 00:00:00

abstract：BACKGROUND:Natural products play a significant role in human health in relation to the prevention and treatment of inflammatory conditions. One of the plants with great medicinal potentials is Diospyros kaki which is mainly cultivated in Asian countries including Korea, Japan, and China. Astringent D. kaki is a wild sp...

journal_title：BMC complementary and alternative medicine

authors： Choi J,Kim MJ,Komakech R,Jung H,Kang Y

更新日期：2019-09-23 00:00:00

abstract：BACKGROUND:Mineral Pitch (MP) is a dark brown coloured humic matter originating from high altitude rocks. It is an Ayurvedic medicinal food, commonly used by the people of the Himalayan regions of Nepal and India for various body ailments. METHODS:The Huh-7 cells were treated with different concentrations of MP for 24...

journal_title：BMC complementary and alternative medicine

authors： Pant K,Gupta P,Damania P,Yadav AK,Gupta A,Ashraf A,Venugopal SK

更新日期：2016-05-27 00:00:00

abstract：BACKGROUND:Lysophosphatidylcholine (lysoPC), a metabolite from membrane phospholipids, accumulates in the ischemic myocardium and plays an important role in the development of myocardial dysfunction ventricular arrhythmia. In this study, we investigated if baicalein, a major component of Huang Qui, can protect against ...

journal_title：BMC complementary and alternative medicine

authors： Chen HM,Hsu JH,Liou SF,Chen TJ,Chen LY,Chiu CC,Yeh JL

更新日期：2014-07-09 00:00:00

abstract：BACKGROUND:The ethanol extract of KOTMIN13, composed of Inula japonica Flowers, Trichosanthes kirilowii Semen, Peucedanum praeruptorum Radix, and Allium macrostemon Bulbs, was investigated for its anti-asthmatic and anti-allergic activities. METHODS:The anti-asthmatic effects of KOTMIN13 were evaluated on ovalbumin (O...

journal_title：BMC complementary and alternative medicine

authors： Lee E,Kim SG,Park NY,Park HH,Jeong KT,Choi J,Lee IH,Lee H,Kim KJ,Lee E

更新日期：2016-06-06 00:00:00

abstract：BACKGROUND:Green tea has polyphenols like flavonoids and catechins; mainly epigallocatechin-3-gallate (EGCG), epicatechin gallate (ECG), epigallocatechin (EGC) and epicatechin (EC), out of which EGCG is of higher abundance. EGCG has shown preventive role in hypercholesterolemia. However, due to low oral bioavailability...

journal_title：BMC complementary and alternative medicine

authors： Pandit AP,Joshi SR,Dalal PS,Patole VC

更新日期：2019-06-13 00:00:00

abstract：BACKGROUND:Abalone has long been used as a valuable food source in East Asian countries. Although the nutritional importance of abalone has been reported through in vitro and in vivo studies, there is little evidence about the potential anti-tumor effects of abalone visceral extract. The aim of the present study is to ...

journal_title：BMC complementary and alternative medicine

authors： Lee CG,Kwon HK,Ryu JH,Kang SJ,Im CR,Ii Kim J,Im SH

更新日期：2010-10-20 00:00:00

abstract：BACKGROUND:Soshiho-tang (SST, Xiao-chai-hu-tang in Chinese and Sho-saiko-to in Japanese), an oriental herbal formula, is used for treatment of chronic liver diseases. Although many researchers have studied the pharmacological properties of SST, information about its safety and toxicity is limited. Therefore, we evaluat...

journal_title：BMC complementary and alternative medicine

authors： Shin IS,Lee MY,Kim Y,Seo CS,Kim JH,Shin HK

更新日期：2012-12-27 00:00:00

abstract：BACKGROUND:Musk is widely used in clinical practice for its anti-cancer properties. Here, we treated various types of cancer using musk to determine which cancers are sensitive to musk treatment. We also compared effects of native musk and synthetic musk ketone in cancer cells. Furthermore, we investigated mechanisms u...

journal_title：BMC complementary and alternative medicine

authors： Xu L,Cao Y

更新日期：2016-12-08 00:00:00

abstract：BACKGROUND:The use of CAM by pregnant women is very popular in developed countries. The trend is increasing globally and lack of evidence of safety particularly when used during pregnancy may lead to complications. Pregnancy is a vulnerable period especially during the first trimester. There is scarcity of empirical ev...

journal_title：BMC complementary and alternative medicine

authors： Onyiapat JL,Okafor C,Okoronkwo I,Anarado A,Chukwukelu E,Nwaneri A,Okpala P

更新日期：2017-04-04 00:00:00

abstract：BACKGROUND:The use of edible plants is an integral part of dietary behavior in the West region of Cameroon. Dorstenia psilurus (Moraceae) is widely used as spice and as medicinal plant for the treatment of several diseases in Cameroon. The aim of this study is to investigate the cytotoxic and apoptotic potential of met...

journal_title：BMC complementary and alternative medicine

authors： Pieme CA,Guru SK,Ambassa P,Kumar S,Ngameni B,Ngogang JY,Bhushan S,Saxena AK

更新日期：2013-09-10 00:00:00

abstract：BACKGROUND:Blood stasis syndrome (BSS) is a general pattern identification and refers to pathological stagnation of blood circulation, dysfunction of endothelial cells or metabolic disorder in traditional Korean medicine (TKM). Dohongsamul-Tang (DHSMT) is a well-known traditional herbal formula which used for treatment...

journal_title：BMC complementary and alternative medicine

authors： Shim EH,Lee H,Lee MS,You S

更新日期：2017-12-19 00:00:00

abstract：BACKGROUND:Although many physiological functions of Coprinus comatus have been reported, there has been no report on the antinociceptive activity of Coprinus comatus. Therefore, the objective of the present study is to demonstrate the production, isolation, and biological properties of triglycerides (TFC) of the fermen...

journal_title：BMC complementary and alternative medicine

authors： Ren J,Shi JL,Han CC,Liu ZQ,Guo JY

更新日期：2012-04-24 00:00:00

abstract：BACKGROUND:Previous study showed that extracts from Croton macrostachyus (Euphorbiaceae) exhibit analgesic effects in acute pain models. The present study evaluates the antinociceptive properties of the methanol/methylene chloride extract (MECM) of the stem bark of this plant using mice models of persistent inflammator...

journal_title：BMC complementary and alternative medicine

authors： Nguelefack TB,Dutra RC,Paszcuk AF,de Andrade EL,Calixto JB

更新日期：2015-08-25 00:00:00

abstract：BACKGROUND:Andrographis paniculata (Burm. f.) Nees (APN), a principal constituent of a famous traditional Chinese medicine Fukeqianjin tablet which is used for the treatment of pelvic inflammatory disease (PID), has been reported to have anti-inflammatory effect in vitro. However, whether it has pharmacological effect ...

journal_title：BMC complementary and alternative medicine

authors： Zou W,Xiao Z,Wen X,Luo J,Chen S,Cheng Z,Xiang D,Hu J,He J

更新日期：2016-11-25 00:00:00

abstract：BACKGROUND:Evidence suggests yoga is a safe and effective intervention for the management of physical and psychosocial symptoms associated with musculoskeletal conditions. However, heterogeneity in the components and reporting of clinical yoga trials impedes both the generalization of study results and the replication ...

journal_title：BMC complementary and alternative medicine

authors： Ward L,Stebbings S,Sherman KJ,Cherkin D,Baxter GD

更新日期：2014-06-18 00:00:00

abstract：BACKGROUND:Conventional scientific studies had supported the use of polysaccharides and β-glucans from a number of fungi, including Ganoderma lucidum for the treatment of recurrent oral ulceration (ROU). Our aim of the present study was to evaluate whether freeze-dried powder from G. lucidum mycelia (FDPGLM) prevents R...

journal_title：BMC complementary and alternative medicine

authors： Xie L,Zhong X,Liu D,Liu L,Xia Z

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Astragaloside IV (AS-IV) was reported to play a role in improving diabetic nephropathy (DN), however, the underlying mechanisms still remain unclear. The aim of the present study is to investigate whether AS-IV ameliorates DN via the regulation of endothelial nitric oxide synthase (eNOS). METHODS:DN model w...

journal_title：BMC complementary and alternative medicine

authors： Fan Y,Fan H,Zhu B,Zhou Y,Liu Q,Li P

更新日期：2019-12-05 00:00:00

abstract：BACKGROUND:Acetaminophen (APAP)-induced toxicity is a predominant cause of acute hepatic and renal failure. In both humans and rodents toxicity begins with a reactive metabolite that binds to proteins. This leads to mitochondrial dysfunction and nuclear DNA fragmentation resulting in necrotic cell death. Pleurotus ostr...

journal_title：BMC complementary and alternative medicine

authors： Naguib YM,Azmy RM,Samaka RM,Salem MF

更新日期：2014-12-15 00:00:00

abstract：BACKGROUND:Insulin resistance is characterized by deficient responses to insulin in its target tissues. In the present study, we examined the effects of L-Citrulline (L-Cit) on insulin sensitivity and signaling cascades in rat hepatoma H4IIE cells and SHRSP.Z-Leprfa/IzmDmcr rats. METHODS:H4IIE cells were pretreated in...

journal_title：BMC complementary and alternative medicine

authors： Yoshitomi H,Momoo M,Ma X,Huang Y,Suguro S,Yamagishi Y,Gao M

更新日期：2015-06-18 00:00:00

abstract：BACKGROUND:Carrageenan is a linear sulphated polysaccharide extracted from red seaweed of the Rhodophyceae family. It has broad spectrum of applications in biomedical and biopharmaceutical field. In this study, we determined the cytotoxicity of degraded and undegraded carrageenan in human intestine (Caco-2; cancer and ...

journal_title：BMC complementary and alternative medicine

authors： Ariffin SH,Yeen WW,Abidin IZ,Abdul Wahab RM,Ariffin ZZ,Senafi S

更新日期：2014-12-17 00:00:00

abstract：BACKGROUND:Phaleria macrocarpa (Scheff.) Boerl (Thymelaceae) originates from Papua Island, Indonesia and grows in tropical areas. The different parts of the fruit of P. macrocarpa were evaluated for antioxidant, anti-inflammatory, and cytotoxic activities. METHODS:Phaleria macrocarpa fruit were divided into pericarp, ...

journal_title：BMC complementary and alternative medicine

authors： Hendra R,Ahmad S,Oskoueian E,Sukari A,Shukor MY

更新日期：2011-11-09 00:00:00

abstract：BACKGROUND:Lung cancer is one of the leading causes of cancer related deaths worldwide. Marine microalgae are a source of biologically active compounds and are widely consumed as a nutritional supplement in East Asian countries. It has been reported that Chlorella or Chlorella extracts have various beneficial pharmacol...

journal_title：BMC complementary and alternative medicine

authors： Lin PY,Tsai CT,Chuang WL,Chao YH,Pan IH,Chen YK,Lin CC,Wang BY

更新日期：2017-02-01 00:00:00