Abstract:
INTRODUCTION:Alcohol use disorders (AUDs) and mood disorders commonly co-occur, and are associated with a range of negative outcomes for patients. Mobile phone technology has the potential to provide personalised support for such patients and potentially improve outcomes in this difficult-to-treat cohort. The aim of this study is to examine whether receiving supporting SMS text messages, following discharge from an inpatient dual diagnosis treatment programme, has a positive impact on mood and alcohol abstinence in patients with an AUD and a comorbid mood disorder. METHODS AND ANALYSIS:The present study is a single-blind randomised controlled trial. Patients aged 18-70 years who meet the criteria for both alcohol dependency syndrome/alcohol abuse and either major depressive disorder or bipolar disorder according to the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders IV Axis I will be randomised to receive twice-daily supportive SMS text messages for 6 months plus treatment as usual, or treatment as usual alone, and will be followed-up at 3, 6, 9 and 12 months postdischarge. Primary outcome measures will include changes from baseline in cumulative abstinence duration, which will be expressed as the proportion of days abstinent from alcohol in the preceding 90 days, and changes from baseline in Beck Depression Inventory scores. ETHICS AND DISSEMINATION:The trial has received full ethical approval from the St. Patrick's Hospital Research Ethics Committee (protocol 13/14). Results of the trial will be disseminated through peer-reviewed journal articles and at academic conferences. TRIAL REGISTRATION NUMBER:NCT02404662; Pre-results.
journal_name
BMJ Openjournal_title
BMJ openauthors
Hartnett D,Murphy E,Kehoe E,Agyapong V,McLoughlin DM,Farren Cdoi
10.1136/bmjopen-2016-013587subject
Has Abstractpub_date
2017-05-29 00:00:00pages
e013587issue
5issn
2044-6055pii
bmjopen-2016-013587journal_volume
7pub_type
杂志文章,随机对照试验相关文献
BMJ Open文献大全abstract:OBJECTIVES:Computer-administered cognitive-behavioural therapy (CCBT) may be a promising treatment for adolescents with depression, particularly due to its increased availability and accessibility. The feasibility of delivering a randomised controlled trial (RCT) comparing a CCBT program (Stressbusters) with an attenti...
journal_title:BMJ open
pub_type: 杂志文章,随机对照试验
doi:10.1136/bmjopen-2016-012834
更新日期:2017-01-27 00:00:00
abstract:OBJECTIVE:The evaluation of discomfort in paediatric research is scarcely evidence-based. In this study, we make a start in describing children's self-reported discomfort during common medical research procedures and compare this with discomfort during dental check-ups which can be considered as a reference level of a ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2017-016077
更新日期:2017-08-01 00:00:00
abstract:OBJECTIVES:To compare the risk profile of women giving birth in private and public hospitals and the rate of obstetric intervention during birth compared with previous published rates from a decade ago. DESIGN:Population-based descriptive study. SETTING:New South Wales, Australia. PARTICIPANTS:691 738 women giving b...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2012-001723
更新日期:2012-09-10 00:00:00
abstract:OBJECTIVE:Our cross-sectional study aimed at evaluating the diagnostic performance of Focused Assessment with Sonography for HIV-associated tuberculosis (FASH) to detect extrapulmonary tuberculosis in extremely resource-limited settings, with visceral leishmaniasis as a differential diagnosis with overlapping sonograph...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-027179
更新日期:2019-04-02 00:00:00
abstract:OBJECTIVE:To measure poverty-based disparities in inpatient length of stay for paediatric hospitalisations. In particular, this paper examines the relationship between municipality level poverty rates and length of stay, accounting for individual level characteristics. DESIGN:We use patient discharge data to conduct a...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-034512
更新日期:2020-08-16 00:00:00
abstract:OBJECTIVES:To explore the nature of images tagged as self-harm on popular social media sites and what this might tell us about how these sites are used. DESIGN:A visual content and thematic analysis of a sample of 602 images captured from Twitter, Instagram and Tumblr. RESULTS:Over half the images tagged as self-harm...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-027006
更新日期:2019-02-19 00:00:00
abstract:OBJECTIVE:Little is known about the potential health effects of eating organic food either in the general population or during pregnancy. The aim of this study was to examine associations between organic food consumption during pregnancy and the risk of pre-eclampsia among nulliparous Norwegian women. DESIGN:Prospecti...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2014-006143
更新日期:2014-09-10 00:00:00
abstract:OBJECTIVES:The aim of the study was to explore what components of the General Medical Council's (GMC) Quality Assurance Framework work, for whom, in what circumstances and how? SETTING:UK undergraduate and postgraduate medical education and training. PARTICIPANTS:We conducted interviews with a stratified sample of 36...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-033614
更新日期:2019-12-29 00:00:00
abstract:OBJECTIVES:Multimorbidity, defined as the presence of 2 or more chronic medical conditions in an individual, is associated with poorer health outcomes. Several multimorbidity measures exist, and the challenge is to decide which to use preferentially in predicting health outcomes. The study objective was to compare the ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2016-013089
更新日期:2016-09-20 00:00:00
abstract:OBJECTIVE:From 2011 to 2013, the Global Fund (GF) supported needle and syringe programmes in Mexico to prevent transmission of HIV among people who inject drugs. It remains unclear how GF withdrawal affected the costs, quality and coverage of needle and syringe programme provision. DESIGN:Costing study and longitudina...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-026298
更新日期:2019-01-29 00:00:00
abstract:OBJECTIVE:This study was designed to evaluate the severity of subclinical atherosclerosis in patients with asymptomatic impaired fasting glucose (IFG) compared to those with diabetes mellitus (DM) and normal fasting glucose (NFG), as measured by coronary computed tomographic angiography (CCTA). DESIGN:Subjects were di...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2014-005148
更新日期:2016-08-16 00:00:00
abstract:OBJECTIVES:To (1) provide an up-to-date overview of shared decision making (SDM)-models, (2) give insight in the prominence of components present in SDM-models, (3) describe who is identified as responsible within the components (patient, healthcare professional, both, none), (4) show the occurrence of SDM-components o...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-031763
更新日期:2019-12-17 00:00:00
abstract:OBJECTIVES:The choice of doctor is an important issue for patients with cancer, and the reputation of the doctor is the single most important factor for patients to choose a doctor. Media are providing information about the 'best cancer doctor', but they vary widely in their selection methodology. We investigated cance...
journal_title:BMJ open
pub_type: 杂志文章,多中心研究
doi:10.1136/bmjopen-2017-019067
更新日期:2018-05-14 00:00:00
abstract:OBJECTIVE:Evidence-based clinical resources (EBCRs) have the potential to improve diagnostic and therapeutic accuracy. The majority of US teaching medical institutions have incorporated them into clinical training. Many EBCRs are subscription based, and their cost is prohibitive for most clinicians and trainees in low-...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-026947
更新日期:2019-08-08 00:00:00
abstract:OBJECTIVES:Evidence of the extent of poor oral health in the older UK adult population is limited. We describe the prevalence of oral health conditions, using objective clinical and subjective measures, in a population-based study of older men. DESIGN:Cross-sectional study. SETTING AND PARTICIPANTS:A representative s...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2015-009476
更新日期:2015-12-29 00:00:00
abstract:OBJECTIVES:We conducted a systematic survey of the methodological literature to identify recommended approaches for how and what randomised clinical trial (RCT) authors should report on missing participant data and, on the basis of these approaches, to propose guidance for RCT authors. METHODS:We defined missing parti...
journal_title:BMJ open
pub_type: 杂志文章,评审
doi:10.1136/bmjopen-2015-008431
更新日期:2015-12-30 00:00:00
abstract:OBJECTIVE:Preventable hospitalisations are used internationally as a performance indicator for primary care, but the influence of other health system factors remains poorly understood. This study investigated between-hospital variation in rates of preventable hospitalisation. SETTING:Linked health survey and hospital ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-027639
更新日期:2019-02-22 00:00:00
abstract:OBJECTIVES:To assess people's procedural preferences for making medical surrogate decisions, from the perspectives of both a potential surrogate and an incapacitated patient. DESIGN:Computer-assisted telephone interviews. Respondents were randomly assigned either the role of an incapacitated patient or that of a poten...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-022289
更新日期:2018-07-25 00:00:00
abstract:OBJECTIVES:To examine the trends in inhospital mortality for England and Scotland over a 17-year period to determine whether and if so to what extent the time trends differ after controlling for differences in the patients treated. DESIGN:Analysis of retrospective administrative hospital data using descriptive aggrega...
journal_title:BMJ open
pub_type: 杂志文章,多中心研究
doi:10.1136/bmjopen-2017-017195
更新日期:2018-02-21 00:00:00
abstract:INTRODUCTION:The improvement in breast cancer survival rates, along with the expected overdiagnosis and overtreatment associated with breast cancer screening, requires a comprehensive assessment of its burden. Neurological complications can have a devastating impact on these patients; neuropathic pain and chemotherapy-...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2014-006301
更新日期:2014-10-28 00:00:00
abstract:OBJECTIVES:Cardiac rehabilitation (CR) improves outcomes after myocardial infarction (MI), but it is underused in China. The purpose of this study was to develop a set of quality indicators (QIs) to improve clinical practices and to confirm the measurability and performance of the developed QIs for CR in Chinese patien...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2020-039757
更新日期:2020-12-30 00:00:00
abstract:OBJECTIVE:To estimate physical and mental health effects of the Eyjafjallajökull volcanic eruption on nearby residents. DESIGN:Cross-sectional study. SETTING:The Icelandic volcano Eyjafjallajökull erupted on 14 April 2010. The eruption lasted for about 6 weeks and was explosive, ejecting some 8 million tons of fine p...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2011-000343
更新日期:2012-03-08 00:00:00
abstract:INTRODUCTION:Cognitive changes after anaesthesia and surgery, such as delirium and postoperative cognitive dysfunction (POCD), are common and lead to poor outcomes and increased healthcare costs. While several interventions for delirium exist, there are no effective treatment strategies for POCD. Understanding the risk...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-024259
更新日期:2019-02-24 00:00:00
abstract:INTRODUCTION:High-flow nasal oxygen (HFNO) use in adults hospitalised with acute respiratory failure (ARF) is increasing. However, evidence to support widespread use of HFNO compared with non-invasive ventilation (NIV) and conventional oxygen therapy (COT) is unclear. This protocol describes the methods for a systemati...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-034956
更新日期:2020-02-12 00:00:00
abstract:INTRODUCTION:Asthma is a variable lung condition whereby patients experience periods of controlled and uncontrolled asthma symptoms. Patients who experience prolonged periods of uncontrolled asthma have a higher incidence of exacerbations and increased morbidity and mortality rates. The ability to determine and to pred...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2016-013935
更新日期:2017-01-24 00:00:00
abstract:OBJECTIVES:To describe the effect of in utero exposure to the buprenorphine+naloxone combination product in a rural and remote population. SETTING:A district hospital that services rural and remote, fly-in communities in Northwestern Ontario, Canada. PARTICIPANTS:A retrospective cohort study was conducted of 855 moth...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2016-011774
更新日期:2016-10-31 00:00:00
abstract:INTRODUCTION:Unprecedented global efforts to prevent malaria morbidity and mortality in sub-Saharan Africa have saved hundreds of thousands of lives across the continent in the last two decades. This study aims to determine how the comparative efficacy and safety of available malaria control interventions intended to i...
journal_title:BMJ open
pub_type: 杂志文章,meta分析
doi:10.1136/bmjopen-2018-024313
更新日期:2019-02-22 00:00:00
abstract:PURPOSE:To design a linked hospital database using administrative and clinical information to describe associations that predict infectious diseases outcomes, including long-term mortality. PARTICIPANTS:A retrospective cohort of Townsville Hospital inpatients discharged with an International Classification of Diseases...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-034845
更新日期:2020-03-18 00:00:00
abstract:OBJECTIVES:Amid a political agenda for integrated, high-value care, the UK is implementing its Low Back and Radicular Pain Pathway. To align care with need, it is imperative to understand the patients' perspective. The purpose of this study was, therefore, to explore how people experience being managed for sciatica wit...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2020-037157
更新日期:2020-06-11 00:00:00
abstract:INTRODUCTION:Amyotrophic lateral sclerosis (ALS) is a representative rare disease characterised by progressive, fatal motor neuron degeneration. Due to the unknown aetiology and variability of the phenotypes, there are no accurate reports concerning the epidemiology or clinical characteristics of the disease. The low p...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2020-042603
更新日期:2020-12-04 00:00:00