Multicentre, prospective registry study of amyotrophic lateral sclerosis in mainland China (CHALSR): study protocol.

abstract：INTRODUCTION:Perioperative benzodiazepines are used because of their anxiolytic, sedative and amnestic effects. Evidence has demonstrated an association of benzodiazepines with adverse neuropsychiatric effects. Nonetheless, because of their potential benefits, perioperative benzodiazepines continue to be used routinely...

journal_title：BMJ open

authors： Spence J,Young J,Alhazzani W,Whitlock R,D'Aragon F,Um K,Mazer D,Beaver C,Jacobsohn E,Belley-Cote E

更新日期：2019-12-11 00:00:00

abstract：OBJECTIVES:We piloted an intervention to determine if support from a case manager would assist adults being investigated for tuberculosis (TB) to link into TB and HIV care. DESIGN:Pilot interventional cohort study. PARTICIPANTS AND SETTING:Patients identified by primary healthcare clinic staff in South Africa as need...

journal_title：BMJ open

authors： Maraba N,Chihota V,McCarthy K,Churchyard GJ,Grant AD

更新日期：2018-05-24 00:00:00

abstract：OBJECTIVES:Despite the increasing number of interventions aiming to integrate cervical cancer screening into HIV clinics in sub-Saharan Africa, Women living with HIV (WLHIV) still have a high risk of developing cervical cancer. The aim of this study was to estimate the coverage of cervical cancer screening and associat...

journal_title：BMJ open

authors： Tchounga B,Boni SP,Koffi JJ,Horo AG,Tanon A,Messou E,Koulé SO,Adoubi I,Ekouevi DK,Jaquet A

更新日期：2019-08-30 00:00:00

abstract：OBJECTIVE:To examine patterns of, and decision-making processes, informing referrals for inpatient access to integrative medicine (IM) services at a large, acute care hospital. DESIGN:Retrospective electronic health record review and structured qualitative interviews. SETTING:A 630-bed tertiary care hospital with an ...

journal_title：BMJ open

authors： Griffin KH,Nate KC,Rivard RL,Christianson JB,Dusek JA

更新日期：2016-07-25 00:00:00

abstract：INTRODUCTION:Stroke is among the leading causes of death and disability worldwide. Poststroke cognitive impairment is a common sequela of stroke. The burden of cognitive impairment poststroke has significant impacts on the individual poststroke, their family and wider society. Despite the prevalence and associated burd...

journal_title：BMJ open

authors： O Donoghue M,Boland P,Galvin R,Coote S,Hayes S

更新日期：2019-11-07 00:00:00

abstract：OBJECTIVE:Public opinion and support can be powerful mandates for smoke-free policy. However, the scarcity of evidence on public opinion among Malaysians necessitates further investigation. Therefore, this study aimed to determine the level of support for smoke-free policy at various public domains and its associated f...

journal_title：BMJ open

authors： Kuang Hock L,Hui Li L,Chien Huey T,Yuvaneswary V,Sayan P,Muhd Yusoff MF,Kuang Kuay L,Miaw Yn L,Kee Chee C,Sumarni Mohd G

更新日期：2019-02-12 00:00:00

abstract：OBJECTIVE:To estimate the time spent by the researchers for preparing grant proposals, and to examine whether spending more time increase the chances of success. DESIGN:Observational study. SETTING:The National Health and Medical Research Council (NHMRC) of Australia. PARTICIPANTS:Researchers who submitted one or mo...

journal_title：BMJ open

authors： Herbert DL,Barnett AG,Clarke P,Graves N

更新日期：2013-05-28 00:00:00

abstract：BACKGROUND AND OBJECTIVE:A comparison of sick leave in pregnancy between countries is difficult as most studies have been conducted in single countries in Scandinavia. The objective of this study was to explore patterns of and reasons for sick leave during pregnancy on a multinational level, focusing on medication use ...

journal_title：BMJ open

authors： Truong BT,Lupattelli A,Kristensen P,Nordeng H

更新日期：2017-08-03 00:00:00

abstract：OBJECTIVE:To compare the benefits and harms of a Dutch 10-session Community Occupational Therapy programme for patients with Alzheimer's disease with the impact of a one session consultation at home in German routine healthcare. DESIGN:A seven-centre, parallel group, active controlled randomised controlled trial. Pati...

journal_title：BMJ open

authors： Voigt-Radloff S,Graff M,Leonhart R,Schornstein K,Jessen F,Bohlken J,Metz B,Fellgiebel A,Dodel R,Eschweiler G,Vernooij-Dassen M,Olde Rikkert M,Hüll M

更新日期：2011-08-09 00:00:00

abstract：INTRODUCTION:'Emergency medicine (EM) in the UK has a medical staffing crisis.' Inadequate staffing, in EM and across healthcare, is a problem that affects the quality of patient care globally. Retention of doctors in EM is a particularly acute problem in the UK's National Health Service. Sustainable careers in healthc...

journal_title：BMJ open

authors： Darbyshire D,Brewster L,Isba R,Body R,Goodwin D

更新日期：2020-11-30 00:00:00

abstract：OBJECTIVES:To compare the efficacy of hypnotherapy versus gabapentin for the treatment of hot flashes in breast cancer survivors, and to evaluate the feasibility of conducting a clinical trial comparing a drug with a complementary or alternative method (CAM). DESIGN:Prospective randomised trial. SETTING:Breast health...

journal_title：BMJ open

authors： Maclaughlan David S,Salzillo S,Bowe P,Scuncio S,Malit B,Raker C,Gass JS,Granai CO,Dizon DS

更新日期：2013-09-10 00:00:00

abstract：INTRODUCTION:Cannabis use and dependence is a serious health and criminal justice issue among incarcerated populations internationally. Upon abrupt, enforced cessation of cannabis, prisoners may suffer irritability and anger that can lead to threatening behaviour, intimidation, violence, sleep disturbances and self-har...

journal_title：BMJ open

authors： Rogerson B,Copeland J,Buttner P,Bohanna I,Cadet-James Y,Sarnyai Z,Clough AR

更新日期：2013-05-28 00:00:00

abstract：OBJECTIVES:To identify the differential effects of patient, health service, temporal and geographic factors on length of stay (LOS) for chronic obstructive pulmonary disease (COPD)-related admissions. DESIGN:We used stratified Cox proportional hazard model to evaluate the association between LOS and patient, health se...

journal_title：BMJ open

authors： Agboado G,Peters J,Donkin L

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVES:To identify rates of potentially preventable complications for dementia patients compared with non-dementia patients. DESIGN:Retrospective cohort design using hospital discharge data for dementia patients, case matched on sex, age, comorbidity and surgical status on a 1 : 4 ratio to non-dementia patients. ...

journal_title：BMJ open

authors： Bail K,Berry H,Grealish L,Draper B,Karmel R,Gibson D,Peut A

更新日期：2013-06-20 00:00:00

abstract：OBJECTIVES:This study aimed to report the proportion of women with a new diagnosis of cervical cancer recommended for curative hysterectomy as well as associated factors. We also report recommended treatments by stage and patterns of treatment initiation. DESIGN:This was an observational cohort study. Inperson surveys...

journal_title：BMJ open

authors： Swanson M,Nakalembe M,Chen LM,Ueda S,Namugga J,Nakisige C,Huchko MJ

更新日期：2020-12-12 00:00:00

abstract：OBJECTIVES:A central tenet of organised cancer screening is that all persons in a target population are invited. The aims of this study were to identify participant and physician factors associated with response to mailed physician-linked invitations (study 1) and to evaluate their effectiveness in an organised colorec...

journal_title：BMJ open

authors： Tinmouth J,Baxter NN,Paszat LF,Rabeneck L,Sutradhar R,Yun L

更新日期：2014-03-12 00:00:00

abstract：INTRODUCTION:Low back pain (LBP) is a leading cause of disability associated with high healthcare utilisation and costs. Mental health symptoms are negative prognostic factors for LBP recovery; however, no population-based studies have assessed the joint effects of LBP and mental health symptoms on healthcare utilisati...

journal_title：BMJ open

authors： Wong JJ,Côté P,Tricco AC,Rosella LC

更新日期：2019-09-27 00:00:00

abstract：INTRODUCTION:Obesity is significant risk factor for venous thromboembolism (VTE); however, the related mechanisms remain unclear. Previous studies have suggested that this might be related to physical factors including anthropometric measures. We intend to conduct a systematic review and meta-analysis of prospective st...

journal_title：BMJ open

authors： Kaze AD,Bigna JJ,Nansseu JR,Noubiap JJ

更新日期：2018-03-31 00:00:00

abstract：OBJECTIVE:To describe the prevalence of statin utilisation by people aged over 50 years in Ireland and the factors associated with the likelihood of using a statin, focusing particularly on those using statins for primary prevention of cardiovascular disease (CVD). METHODS:This is a cross-sectional analysis of cardiov...

journal_title：BMJ open

authors： Byrne P,Cullinan J,Murphy C,Smith SM

更新日期：2018-02-08 00:00:00

abstract：CONTEXT AND OBJECTIVE:Standards for clinical practice guidelines require explicit statements regarding how values and preferences influence recommendations. However, no cancer screening guideline has addressed the key question of what magnitude of benefit people require to undergo screening, given its harms and burdens...

journal_title：BMJ open

authors： Helsingen LM,Zeng L,Siemieniuk RA,Lytvyn L,Vandvik PO,Agoritsas T,Bretthauer M,Guyatt G

更新日期：2020-12-02 00:00:00

abstract：OBJECTIVES:To assess the current health of the Deaf community in the UK and compare with the general population. DESIGN:A quota sample of adult Deaf British Sign Language (BSL) users underwent a health assessment and interview in 2012-2013. Comparative data were obtained from the Health Survey for England (HSE) 2011 a...

journal_title：BMJ open

authors： Emond A,Ridd M,Sutherland H,Allsop L,Alexander A,Kyle J

更新日期：2015-01-25 00:00:00

abstract：OBJECTIVE:To identify, summarise and synthesise available literature on the effectiveness of implementation strategies for optimising implementation of complex interventions in primary care. DESIGN:Systematic review of reviews. DATA SOURCES:MEDLINE, EMBASE, CINAHL, Cochrane Library and PsychINFO were searched, from f...

journal_title：BMJ open

authors： Lau R,Stevenson F,Ong BN,Dziedzic K,Treweek S,Eldridge S,Everitt H,Kennedy A,Qureshi N,Rogers A,Peacock R,Murray E

更新日期：2015-12-23 00:00:00

abstract：BACKGROUND:Specialist Lifestyle Management (SLiM) is a structured patient education and self-management group weight management programme. Each session is run monthly over a 6-month period providing a less intensive long-term approach. The groups are patient-centred incorporating educational, motivational, behavioural ...

journal_title：BMJ open

authors： Brown A,Gouldstone A,Fox E,Field A,Todd W,Shakher J,Bellary S,Teh MM,Azam M,John R,Jagielski A,Arora T,Thomas GN,Taheri S

更新日期：2015-04-08 00:00:00

abstract：INTRODUCTION:Neurological injury remains the major cause of morbidity and mortality following open aortic arch repair. Systemic hypothermia along with antegrade cerebral perfusion (ACP) is the accepted cerebral protection approach, with axillary artery cannulation being the most common technique used to establish ACP. ...

journal_title：BMJ open

authors： Garg V,Peterson MD,Chu MW,Ouzounian M,MacArthur RG,Bozinovski J,El-Hamamsy I,Victor Chu F,Garg A,Hall J,Thorpe KE,Dhingra N,Teoh H,Marotta TR,Latter DA,Quan A,Mamdani M,Juni P,David Mazer C,Verma S

更新日期：2017-06-10 00:00:00

abstract：OBJECTIVE:To analyse the completeness in GallRiks of the follow-up frequency in relation to the intraoperative and postoperative outcome. DESIGN:Population-based register study. SETTING:Data from the national Swedish Registry for Gallstone Surgery and Endoscopic Retrograde Cholangiopancreatography (ERCP), GallRiks. ...

journal_title：BMJ open

authors： Enochsson L,Blohm M,Sandblom G,Jonas E,Hallerbäck B,Lundell L,Österberg J

更新日期：2018-01-23 00:00:00

abstract：OBJECTIVE:To investigate mental and physical health of mothers exposed to recent and early postpartum intimate partner violence (IPV) in the 10 years after having their first child. DESIGN:Prospective pregnancy cohort study. SETTING:Women were recruited at six metropolitan public maternity hospitals in Melbourne, Aus...

journal_title：BMJ open

authors： Brown SJ,Conway LJ,FitzPatrick KM,Hegarty K,Mensah FK,Papadopoullos S,Woolhouse H,Giallo R,Gartland D

更新日期：2020-12-21 00:00:00

abstract：OBJECTIVES:To examine if the estimated glomerular filtration rate (eGFR) slope over a 5-year period is related to incident cardiovascular (CV) events in the following 5 years. DESIGN:Retrospective cohort study. SETTING:Primary care. PARTICIPANTS:All patients aged ≥50 years with at least four eGFR measurements betwee...

journal_title：BMJ open

authors： Van Pottelbergh G,Mamouris P,Opdeweegh N,Vaes B,Goderis G,Van Den Akker M

更新日期：2018-11-12 00:00:00

abstract：OBJECTIVES:To examine the burden of comorbidity, polypharmacy and herpes zoster (HZ), an infectious disease, and its main complication post-herpetic neuralgia (PHN) in young (50-70 years of age: 70-) and old (≥ 70 years of age: 70+) patients. DESIGN:Post hoc analysis of the results of the 12-month longitudinal prospec...

journal_title：BMJ open

authors： Pickering G,Gavazzi G,Gaillat J,Paccalin M,Bloch K,Bouhassira D

更新日期：2016-02-18 00:00:00

abstract：INTRODUCTION:In the recent past, training systems using an interactive virtual environment have been introduced to neurorehabilitation. Such systems can be applied to encourage purposeful limb movements and will increasingly be used at home by the individual patient. Therefore, an integrated valid and reliable assessme...

journal_title：BMJ open

authors： Behrendt F,Schuster-Amft C

更新日期：2018-07-16 00:00:00

abstract：OBJECTIVES:Pressures on healthcare systems due to COVID-19 has impacted patients without COVID-19 with surgery disproportionally affected. This study aims to understand the impact on the initial management of patients with brain tumours by measuring changes to normal multidisciplinary team (MDT) decision making. DESIG...

journal_title：BMJ open

authors： Price SJ,Joannides A,Plaha P,Afshari FT,Albanese E,Barua NU,Chan HW,Critchley G,Flannery T,Fountain DM,Mathew RK,Piper RJ,Poon MT,Rajaraman C,Rominiyi O,Smith S,Solomou G,Solth A,Surash S,Wykes V,Watts C,Bulbeck

更新日期：2020-08-16 00:00:00