Abstract:
INTRODUCTION:The prevalence of dementia is increasing without a known cure, resulting in an increasing number of informal caregivers. Caring for a person with dementia results in increased stress and depressive symptoms. There are several behavioural interventions designed to alleviate stress and depressive symptoms in caregivers of persons with dementia with evidence of efficacy. Two of the best-known interventions are the New York University Caregiver Intervention (NYUCI) and the Resources for Enhancing Alzheimer's Caregivers Health (REACH). The effectiveness of the NYUCI and REACH has never been compared. There is also a paucity of data on which interventions are more effective in Hispanics in New York City. Thus, we proposed the Northern Manhattan Hispanic Caregiver intervention Effectiveness Study (NHiCE), a pragmatic clinical trial designed to compare the effectiveness of adaptations of the NYUCI and the REACH in informal Hispanic caregivers of persons with dementia in New York City. METHODS AND ANALYSIS:NHiCE is a 6-month randomised controlled trial comparing the effectiveness of adaptations of the NYUCI and REACH among 200 Hispanic informal adult caregivers of persons with dementia. The planned number of sessions of the NYUCI and REACH are similar. The primary outcome measures are changes from baseline to 6 months in the Zarit Caregiver Burden Scale and Geriatric Depression Scale. Our primary approach to analyses will be intent-to-treat. The primary analyses will use mixed random effects models, and a full information maximum likelihood approach, with sensitivity analyses using generalised estimating equation. ETHICS AND DISSEMINATION:NHiCE is approved by the Institutional Review Board of Columbia University Medical Center (protocol AAAM5150). A Data Safety Monitoring Board monitors the progress of the study. Dissemination will include reports of the characteristics of the study participants, as well as a report of the results of the clinical trial. TRIAL REGISTRATION NUMBER:NCT02092987, Pre-results.
journal_name
BMJ Openjournal_title
BMJ openauthors
Luchsinger JA,Burgio L,Mittelman M,Dunner I,Levine JA,Kong J,Silver S,Ramirez M,Teresi JAdoi
10.1136/bmjopen-2016-014082subject
Has Abstractpub_date
2016-11-25 00:00:00pages
e014082issue
11issn
2044-6055pii
bmjopen-2016-014082journal_volume
6pub_type
杂志文章相关文献
BMJ Open文献大全abstract:OBJECTIVES:To identify and describe the outcomes and facilitating processes of participation at 'Find Your Sense of Tumour' (FYSOT), a 2-day residential programme/conference for young people with cancer, from the perspective of professionals attending and patient representatives. DESIGN:Case study. SETTING:Observatio...
journal_title:BMJ open
pub_type: 杂志文章,多中心研究
doi:10.1136/bmjopen-2016-015309
更新日期:2017-07-13 00:00:00
abstract:INTRODUCTION:Controlled trials support the efficacy of exercise as a treatment modality for chronic conditions, yet effectiveness of real-world Exercise Physiology services is yet to be determined. This study will investigate the efficacy and cost-effectiveness of services provided by Accredited Exercise Physiologists ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-027610
更新日期:2019-08-21 00:00:00
abstract:INTRODUCTION:Inappropriate use of antimicrobials in hospitals contributes to antimicrobial resistance. Antimicrobial stewardship (AMS) interventions aim to improve antimicrobial prescribing, but they are often resource and personnel intensive. Computerised decision supportsystems (CDSSs) seem a promising tool to improv...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-022666
更新日期:2018-06-27 00:00:00
abstract:OBJECTIVES:To measure work-related burnout in all groups of health service staff during the COVID-19 pandemic and to identify factors associated with work-related burnout. DESIGN:Cross-sectional staff survey. SETTING:All staff grades and types across primary and secondary care in a single National Health Service orga...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2020-042591
更新日期:2021-01-28 00:00:00
abstract:OBJECTIVES:To identify the shared research priorities of patients, caregivers and multidisciplinary renal health and social care professionals across Wales for integrated renal health and social care in Wales. DESIGN:Research priority setting exercise adapted from the James Lind Alliance national priority setting part...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2020-036872
更新日期:2020-09-01 00:00:00
abstract:OBJECTIVE:The objective of this study is to assess the determinants of BCG vaccination in Ethiopia from 2016 Ethiopia Demographic and Health Survey (EDHS). SETTING:Since Ethiopia has nine regional states and two administrative cities, sample was taken from all the divisions. The population-based sample was intended to...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-023634
更新日期:2019-02-21 00:00:00
abstract:OBJECTIVES:While bidirectional relationships exist between body weight and physical activity, direction of causality remains uncertain and previous studies have been limited by self-reported activity or weight and small sample size. We investigated the prospective relationships between weight and physical activity. DE...
journal_title:BMJ open
pub_type: 杂志文章,随机对照试验
doi:10.1136/bmjopen-2015-007901
更新日期:2015-08-14 00:00:00
abstract:INTRODUCTION:Physically active cancer survivors have substantially less cancer recurrence and improved survival compared with those who are inactive. However, the majority of survivors (70%-90%) are not meeting the physical activity (PA) guidelines. There are also significant geographic inequalities in cancer survival ...
journal_title:BMJ open
pub_type: 杂志文章,随机对照试验
doi:10.1136/bmjopen-2018-028369
更新日期:2019-05-24 00:00:00
abstract:OBJECTIVES:Childhood asthma is a complex condition where many environmental factors are implicated in causation. The aim of this study was to complete a systematic review of the literature describing associations between environmental exposures and the development of asthma in young children. SETTING:A systematic revi...
journal_title:BMJ open
pub_type: 杂志文章,评审
doi:10.1136/bmjopen-2014-006554
更新日期:2014-11-24 00:00:00
abstract:OBJECTIVE:To use newly available self-assigned ethnicity information to investigate variation in breast cancer screening uptake for women from the 16 specific ethnic groups within the broad Asian, Black and White groups that previous studies report. SETTING:National cancer screening programme services within London. ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2014-005586
更新日期:2014-10-16 00:00:00
abstract:INTRODUCTION:Labour induction in women with a previous caesarean delivery currently uses vaginal prostaglandin E2 (PGE2), which carries the risks of uterine hyperstimulation and scar rupture. We aim to compare the efficacy of mechanical labour induction using a transcervically applied Foley catheter balloon (FCB) with ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-028896
更新日期:2019-11-06 00:00:00
abstract:PURPOSE:Patients receiving extracorporeal membrane oxygenation (ECMO) generally receive proton pump inhibitors (PPIs) or histamine-2 receptor antagonists (H2RAs) to avoid major gastrointestinal bleeding. Our aim was to compare outcomes between patients receiving PPIs and H2RAs for stress ulcer prophylaxis during ECMO. ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2020-037534
更新日期:2020-09-29 00:00:00
abstract:OBJECTIVE:In this study, we assess the performance of public hospitals in Saudi Arabia. We detect the sources of inefficiency and estimate the optimal levels of the resources that provide the current level of health services. We enrich our analysis by employing locations and capacities of the hospitals. DESIGN:We empl...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-031924
更新日期:2020-01-12 00:00:00
abstract:INTRODUCTION:Sexually transmitted infections (STI) are a major public health problem. Condoms provide effective protection but there are many barriers to use. Face-to-face health promotion interventions are resource-intensive and show mixed results. Interactive digital interventions may provide a suitable alternative, ...
journal_title:BMJ open
pub_type: 杂志文章,随机对照试验
doi:10.1136/bmjopen-2014-007552
更新日期:2015-02-16 00:00:00
abstract:INTRODUCTION:Patients with chronic obstructive pulmonary disease (COPD) often have multiple hospitalisations because of exacerbation. Evidence shows disease management programmes are one of the most cost-effective measures to prevent re-hospitalisation for COPD exacerbation, but lack implementation and economic apprais...
journal_title:BMJ open
pub_type: 杂志文章,随机对照试验
doi:10.1136/bmjopen-2015-009988
更新日期:2016-06-15 00:00:00
abstract:INTRODUCTION:Α substantial corpus of literature has sought to describe the information-seeking behaviour of patients with cancer. Yet, available evidence comes mainly from cross-sectional studies, which provide 'snapshots' of patients' information needs and information-seeking styles at a single time point. Only a few ...
journal_title:BMJ open
pub_type: 杂志文章,多中心研究
doi:10.1136/bmjopen-2015-008933
更新日期:2015-10-06 00:00:00
abstract:OBJECTIVES:Examine the relationship between maternal alcohol use disorder and child school attendance outcomes for non-Indigenous and Indigenous children in Western Australia. DESIGN:Population cohort study. SETTING:Routinely collected linked administrative health, education and child protection data. PARTICIPANTS:T...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2016-015650
更新日期:2017-07-11 00:00:00
abstract:OBJECTIVES:Low-income and middle-income countries are undergoing epidemiological transition, however, progression is varied. Bangladesh is simultaneously experiencing continuing burden of communicable diseases and emerging burden of non-communicable diseases (NCDs). For effective use of limited resources, an increased ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-026722
更新日期:2019-10-28 00:00:00
abstract:OBJECTIVE:This study aims to test a Chinese cross-cultural adaptation of the English version of the Person-Centred Care Assessment Tool (P-CAT) and evaluate its psychometric properties. DESIGN:P-CAT was translated/back-translated using established procedures before the psychometric evaluation of the Chinese version wa...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-031580
更新日期:2020-07-13 00:00:00
abstract:OBJECTIVE:To model the long-term cost-effectiveness of consuming milk powder fortified with potassium to decrease systolic blood pressure (SBP) and prevent cardiovascular events. DESIGN:A best case scenario analysis using a Markov model was conducted. PARTICIPANTS:8.67% of 50-79 year olds who regularly consume milk i...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2017-017136
更新日期:2017-09-25 00:00:00
abstract:OBJECTIVE:We aimed to evaluate the safety, efficiency and preferred indication for laparoendoscopic single-site surgery (LESS) compared with conventional laparoscopic (CL) surgery for benign ovarian masses. DESIGN:A systemic review and cumulative meta-analysis were performed in line with the criteria of Grading of Rec...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-032331
更新日期:2020-02-16 00:00:00
abstract:OBJECTIVES:We previously demonstrated that a calcium channel blocker, azelnidipine, improves left ventricular relaxation in patients with hypertension and diastolic dysfunction in a multicentre, Clinical impact of Azelnidipine on Left VentricuLar diastolic function and OutComes in patients with hypertension (CALVLOC) t...
journal_title:BMJ open
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1136/bmjopen-2014-006136
更新日期:2014-09-30 00:00:00
abstract:BACKGROUND:Large gaps exist in the implementation of guideline recommendations for cardiovascular disease (CVD) risk management. Electronic decision support (EDS) systems are promising interventions to close these gaps but few have undergone clinical trial evaluation in Australia. We have developed HealthTracker, a mul...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2012-002177
更新日期:2012-11-19 00:00:00
abstract:INTRODUCTION:Sarcopenia (or loss of muscle mass and function) is a relatively new area within the field of musculoskeletal research and medicine. Investigating whether there is a social gradient, including occupation type and income level, of sarcopenia, as observed for other diseases, will contribute significantly to ...
journal_title:BMJ open
pub_type: 杂志文章,meta分析
doi:10.1136/bmjopen-2017-019088
更新日期:2018-01-13 00:00:00
abstract:OBJECTIVES:Investigating the potential pathways linking shift work and cardiovascular diseases (CVD), this study aimed to identify whether sleep disturbances mediate the relationship between shift work and the metabolic syndrome, a cluster of CVD risk factors. DESIGN:Cross-sectional study. SETTING:A tertiary-level, a...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2014-007327
更新日期:2015-03-10 00:00:00
abstract:INTRODUCTION:Drug-related problems (DRPs) are a major cause of unplanned hospital admissions among elderly people, and transitions of care have been emphasised as a key area for improving patient safety. We have designed a complex clinical pharmacist intervention that targets people ≥75 years of age undergoing transiti...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-036650
更新日期:2020-04-27 00:00:00
abstract:OBJECTIVES:Regular physical exercise may preserve β cell function in newly diagnosed adults with type 1 diabetes (T1D). However, clinical trials to test this theory require the recruitment and retention of adults with new-onset T1D, which can be challenging. We sought to determine the overall experiences of newly diagn...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-022353
更新日期:2018-07-17 00:00:00
abstract:INTRODUCTION:Recent evidence has implicated the precuneus of the medial parietal lobe as one of the first brain areas to show pathological changes in Alzheimer's disease (AD). Damage to the precuneus through focal brain injury is associated with impaired visually guided reaching, particularly for objects in peripheral ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-035021
更新日期:2020-06-04 00:00:00
abstract:OBJECTIVES:To estimate the incidence and epidemiology of catheter-related bloodstream infections (CRBSIs) on a national scale by using prospective epidemiological data from the Swiss Antibiotic Resistance Surveillance System (ANRESIS). DESIGN:Observational study. SETTING:National surveillance from 2008 to 2015 of acu...
journal_title:BMJ open
pub_type: 杂志文章,多中心研究
doi:10.1136/bmjopen-2018-023824
更新日期:2018-12-22 00:00:00
abstract:PURPOSE:The Trivandrum non-alcoholic fatty liver disease (NAFLD) cohort is a population-based study designed to examine the interaction between genetic and lifestyle factors and their association with increased risk of NAFLD within the Indian population. PARTICIPANTS:Between 2013 and 2016, a total of 2222 participants...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-027244
更新日期:2019-05-05 00:00:00