Neutrophil gelatinase-associated lipocalin (NGAL) predicts the occurrence of malaria-induced acute kidney injury.

abstract：BACKGROUND:The objective of this study was to identify attitudes and misconceptions related to acceptance or refusal of indoor residual spraying (IRS) in Tanzania for both the general population and among certain groups (e.g., farmers, fishermen, community leaders, and women). METHODS:This study was a series of qualit...

journal_title：Malaria journal

authors： Kaufman MR,Rweyemamu D,Koenker H,Macha J

更新日期：2012-07-02 00:00:00

abstract：BACKGROUND:Approximately 50 million people (60 %) live in malaria risk areas in Ethiopia, at altitudes below 2000 m. According to official data, 60-70 % of malaria cases are due to Plasmodium falciparum, and 40-30 % by Plasmodium vivax. The species Plasmodium ovale was detected in 2013 in the northwest of the country, ...

journal_title：Malaria journal

authors： Díaz PB,Lozano PM,Rincón JM,García L,Reyes F,Llanes AB

更新日期：2015-09-18 00:00:00

abstract：BACKGROUND:Most of the current biophysical models designed to address the large-scale distribution of malaria assume that transmission of the disease is independent of the vector involved. Another common assumption in these type of model is that the mortality rate of mosquitoes is constant over their life span and that...

journal_title：Malaria journal

authors： Lunde TM,Korecha D,Loha E,Sorteberg A,Lindtjørn B

更新日期：2013-01-23 00:00:00

abstract：BACKGROUND:The diversity of genotyping markers of Plasmodium falciparum depends on transmission intensity. It has been reported that the diversity of the merozoite surface protein 2 (msp2) is greater in areas of high compared to low endemicity, however, results for msp1 were inconsistent. These previous reports relied ...

journal_title：Malaria journal

authors： Schoepflin S,Valsangiacomo F,Lin E,Kiniboro B,Mueller I,Felger I

更新日期：2009-10-30 00:00:00

abstract：BACKGROUND:Global efforts to address the burden of malaria have stagnated in recent years with malaria cases beginning to rise. Substandard and falsified anti-malarial treatments contribute to this stagnation. Poor quality anti-malarials directly affect health outcomes by increasing malaria morbidity and mortality, as ...

journal_title：Malaria journal

authors： Ozawa S,Evans DR,Higgins CR,Laing SK,Awor P

更新日期：2019-01-09 00:00:00

abstract：BACKGROUND:To date, human peripheral blood mononuclear cells (PBMCs) have been used mainly in immune stimulation assays and the interpretation of data can be influenced by the previous immunological history of donors and cross reactivity with other infectious agents. Resolving these limitations requires an alternative ...

journal_title：Malaria journal

authors： Chitsanoor S,Somsri S,Panburana P,Mungthin M,Ubalee R,Emyeam M,Jongwutiwes S,Sattabongkot J,Udomsangpetch R

更新日期：2017-03-27 00:00:00

abstract：BACKGROUND:Recent whole cell in vitro screening campaigns identified thousands of compounds that are active against asexual blood stages of Plasmodium falciparum at submicromolar concentrations. These hits have been made available to the public, providing many novel chemical starting points for anti-malarial drug disco...

journal_title：Malaria journal

authors： Le Manach C,Scheurer C,Sax S,Schleiferböck S,Cabrera DG,Younis Y,Paquet T,Street L,Smith P,Ding XC,Waterson D,Witty MJ,Leroy D,Chibale K,Wittlin S

更新日期：2013-11-16 00:00:00

abstract：:The classic formulae in malaria epidemiology are reviewed that relate entomological parameters to malaria transmission, including mosquito survivorship and age-at-infection, the stability index (S), the human blood index (HBI), proportion of infected mosquitoes, the sporozoite rate, the entomological inoculation rate ...

journal_title：Malaria journal

authors： Smith DL,McKenzie FE

更新日期：2004-06-04 00:00:00

abstract：BACKGROUND:Appropriate case management of suspected malaria in Cambodia is critical given anti-malarial drug resistance in the region. Improving diagnosis and the use of recommended malarial treatments is a challenge in Cambodia where self-treatment and usage of drug cocktails is widespread, a notable difference from m...

journal_title：Malaria journal

authors： O'Connell KA,Samandari G,Phok S,Phou M,Dysoley L,Yeung S,Allen H,Littrell M

更新日期：2012-10-05 00:00:00

abstract：BACKGROUND:Public health pesticides has been the mainstay control of vectors of malaria and other diseases, and public health pests, but there is increasing concern over how these pesticides are being managed. Poor pesticide management could lead to risks to human health and the environment, or diminish the effectivene...

journal_title：Malaria journal

authors： van den Berg H,Yadav RS,Zaim M

更新日期：2014-09-18 00:00:00

abstract：BACKGROUND:Deltamethrin-impregnated, long-lasting insecticidal nets (LLINs) were distributed in the study area from November 2014 to January 2015 to evaluate their impact on malaria transmission in the presence of insecticide-resistant vectors. Studies were carried out in 16 selected clusters in Keshkal sub-district, C...

journal_title：Malaria journal

authors： Kona MP,Kamaraju R,Donnelly MJ,Bhatt RM,Nanda N,Chourasia MK,Swain DK,Suman S,Uragayala S,Kleinschmidt I,Pandey V

更新日期：2018-11-08 00:00:00

abstract：BACKGROUND:The use of artemisinin-based combination therapy (ACT) at the community level has been advocated as a means to increase access to effective antimalarial medicines by high risk groups living in underserved areas, mainly in sub-Saharan Africa. This strategy has been shown to be feasible and acceptable to the c...

journal_title：Malaria journal

authors： Ajayi IO,Browne EN,Bateganya F,Yar D,Happi C,Falade CO,Gbotosho GO,Yusuf B,Boateng S,Mugittu K,Cousens S,Nanyunja M,Pagnoni F

更新日期：2008-09-27 00:00:00

abstract：BACKGROUND:Since Plasmodium falciparum transmission relies exclusively on sexual-stage parasites, several malaria control strategies aim to disrupt this step of the life cycle. Thus, a better understanding of which individuals constitute the primary gametocyte reservoir within an endemic population, and the temporal dy...

journal_title：Malaria journal

authors： Adomako-Ankomah Y,Chenoweth MS,Tocker AM,Doumbia S,Konate D,Doumbouya M,Keita AS,Anderson JM,Fairhurst RM,Diakite M,Miura K,Long CA

更新日期：2017-11-21 00:00:00

abstract：BACKGROUND:The standard in vitro protocol currently in use for drug testing against Plasmodium falciparum, based on the incorporation of the purine [3H]-hypoxanthine, has two serious drawbacks. Firstly it is unsuitable for the testing of drugs that directly or indirectly impact on purine salvage or metabolism. Secondly...

journal_title：Malaria journal

authors： Quashie NB,de Koning HP,Ranford-Cartwright LC

更新日期：2006-10-31 00:00:00

abstract：BACKGROUND:Extensive genetic diversity in the Plasmodium falciparum circumsporozoite protein (PfCSP) is a major contributing factor to the moderate efficacy of the RTS,S/AS01 vaccine. The transmission intensity and rates of recombination within and between populations influence the extent of its genetic diversity. Unde...

journal_title：Malaria journal

authors： Amegashie EA,Amenga-Etego L,Adobor C,Ogoti P,Mbogo K,Amambua-Ngwa A,Ghansah A

更新日期：2020-11-27 00:00:00

abstract：BACKGROUND:Chloroquine-resistant Plasmodium falciparum was first described in the Republic of Vanuatu in the early 1980s. In 1991, the Vanuatu Ministry of Health instituted new treatment guidelines for uncomplicated P. falciparum infection consisting of chloroquine/sulphadoxine-pyrimethamine combination therapy. Chloro...

journal_title：Malaria journal

authors： Kinzer MH,Chand K,Basri H,Lederman ER,Susanti AI,Elyazar I,Taleo G,Rogers WO,Bangs MJ,Maguire JD

更新日期：2010-04-06 00:00:00

abstract：:The hypnozoite reservoir of Plasmodium vivax represents both the greatest obstacle and opportunity for ultimately eradicating this species. It is silent and cannot be diagnosed until it awakens and provokes a clinical attack with attendant morbidity, risk of mortality, and opportunities for onward transmission. The on...

journal_title：Malaria journal

authors： Baird JK,Battle KE,Howes RE

更新日期：2018-01-22 00:00:00

abstract：BACKGROUND:A successful malaria control programme began in 2004 on Bioko Island, Equatorial Guinea. From 2007, the same multiple malaria interventions, though reduced in scope for funding reasons, were introduced to the four mainland provinces of Equatorial Guinea (the continental region) aiming to recreate Bioko's suc...

journal_title：Malaria journal

authors： Rehman AM,Mann AG,Schwabe C,Reddy MR,Roncon Gomes I,Slotman MA,Yellott L,Matias A,Caccone A,Nseng Nchama G,Kleinschmidt I

更新日期：2013-05-07 00:00:00

abstract：BACKGROUND:Agro-ecological systems have been associated with increased malaria intensity. This study determined association between different agro-ecological systems, prevalence of malaria parasitaemia and anaemia in Mvomero district, Tanzania. METHODS:The study was carried out in three agro-ecosystems namely, savanna...

journal_title：Malaria journal

authors： Rumisha SF,Shayo EH,Mboera LEG

更新日期：2019-07-09 00:00:00

abstract：BACKGROUND:Malaria is endemic in the Rajasthali region of the Chittagong Hill Tracts in Bangladesh and the Rajasthali region is the most endemic area of Bangladesh. Quantifying the role of environmental and socio-economic factors in the local spatial patterns of malaria endemicity can contribute to successful malaria c...

journal_title：Malaria journal

authors： Haque U,Soares Magalhães RJ,Mitra D,Kolivras KN,Schmidt WP,Haque R,Glass GE

更新日期：2011-12-15 00:00:00

abstract：BACKGROUND:Species of anopheline mosquitoes are largely distributed over emerged lands around the world and, within the tropics, few areas are without these insects, which are vectors of malaria parasites. Among the exceptions is the Seychelles archipelago in the western Indian Ocean. However, in the Aldabra island gro...

journal_title：Malaria journal

authors： Robert V,Rocamora G,Julienne S,Goodman SM

更新日期：2011-02-08 00:00:00

abstract：BACKGROUND:Knowledge of the population genetics and transmission dynamics of Plasmodium vivax is crucial in predicting the emergence of drug resistance, relapse pattern and novel parasite phenotypes, all of which are relevant to the control of vivax infections. The aim of this study was to analyse changes in the geneti...

journal_title：Malaria journal

authors： Maneerattanasak S,Gosi P,Krudsood S,Tongshoob J,Lanteri CA,Snounou G,Khusmith S

更新日期：2016-02-09 00:00:00

abstract：BACKGROUND:Many malaria-related studies depend on infected red blood cells (iRBCs) as fundamental material; however, infected blood samples from human or animal models include leukocytes (white blood cells or WBCs), especially difficult to separate from iRBCs in cases involving Plasmodium vivax. These host WBCs are a s...

journal_title：Malaria journal

authors： Tao ZY,Xia H,Cao J,Gao Q

更新日期：2011-08-25 00:00:00

abstract：:BACKGROUND: The development of Plasmodium falciparum within human erythrocytes induces a wide array of changes in the ultrastructure, function and antigenic properties of the host cell. Numerous proteins encoded by the parasite have been shown to interact with the erythrocyte membrane. The identification of new intera...

journal_title：Malaria journal

authors： Lauterbach SB,Lanzillotti R,Coetzer TL

更新日期：2003-12-17 00:00:00

abstract：:Malaria vaccines are considered amongst the most important modalities for potential elimination of malaria disease and transmission. Research and development in this field has been an area of intense effort by many groups over the last few decades. Despite this, there is currently no licensed malaria vaccine. Research...

journal_title：Malaria journal

authors： Mwangoka G,Ogutu B,Msambichaka B,Mzee T,Salim N,Kafuruki S,Mpina M,Shekalaghe S,Tanner M,Abdulla S

更新日期：2013-03-04 00:00:00

abstract：BACKGROUND:An initial study of genetic diversity of Plasmodium falciparum in Asembo, western Kenya showed that the parasite maintained overall genetic stability 5 years after insecticide-treated bed net (ITN) introduction in 1997. This study investigates further the genetic diversity of P. falciparum 10 years after ini...

journal_title：Malaria journal

authors： Gatei W,Gimnig JE,Hawley W,Ter Kuile F,Odero C,Iriemenam NC,Shah MP,Howard PP,Omosun YO,Terlouw DJ,Nahlen B,Slutsker L,Hamel MJ,Kariuki S,Walker E,Shi YP

更新日期：2015-12-09 00:00:00

abstract：BACKGROUND:The close relationship between vector-borne diseases and their environment is well documented, especially for diseases with water-dependent vectors such as avian malaria. Mosquitoes are the primary vectors of avian malaria and also the definitive hosts in the disease life cycle. Factors pertinent to mosquito...

journal_title：Malaria journal

authors： Okanga S,Cumming GS,Hockey PA

更新日期：2013-10-25 00:00:00

abstract：BACKGROUND:Primaquine is an important gametocytocidal drug that is combined with conventional malaria treatment for prevention of Plasmodium falciparum malaria transmission. Primaquine has been administered together on the first or the last day of conventional treatment but the impact of primaquine timing has never bee...

journal_title：Malaria journal

authors： Shekalaghe S,Mosha D,Hamad A,Mbaga TA,Mihayo M,Bousema T,Drakeley C,Abdulla S

更新日期：2020-01-21 00:00:00

abstract：BACKGROUND:The production and use of malaria rapid diagnostic tests (RDTs) has risen dramatically over the past 20 years. In view of weak or non-existing in vitro diagnostics (IVD) regulations and post-marketing surveillance (PMS) systems in malaria endemic countries, the World Health Organization, later joined by the ...

journal_title：Malaria journal

authors： Incardona S,Bell D,Campillo A,Cunningham J,Ariey F,Fandeur T,Luchavez J,Luna CA,Ménard D,Nhem S,Sornillo JB,Witkowski B,Katz Z,Dittrich S,Ding XC

更新日期：2020-07-13 00:00:00

abstract：BACKGROUND:Between 2007 and 2013, the Tanzanian public sector received 93.1 million doses of first-line anti-malarial artemisinin-based combination therapy (ACT) in the form of artemether-lumefantrine entirely supplied by funding partners. The introduction of a health facility ACT stock monitoring system using SMS tech...

journal_title：Malaria journal

authors： Mikkelsen-Lopez I,Shango W,Barrington J,Ziegler R,Smith T,deSavigny D

更新日期：2014-05-11 00:00:00