The effectiveness of a nurse-led intervention with the distress thermometer for patients treated with curative intent for breast cancer: design of a randomized controlled trial.

abstract：BACKGROUND:Thymosin β10 (Tβ10) expression is associated with malignant phenotypes in many cancers. However, the role and mechanisms of Tβ10 in liver fluke-associated cholangiocarcinoma (CCA) are not fully understood. In this study, we investigated the expression of Tβ10 in CCA tumor tissues and cell lines as well as mo...

journal_title：BMC cancer

authors： Sribenja S,Sawanyawisuth K,Kraiklang R,Wongkham C,Vaeteewoottacharn K,Obchoei S,Yao Q,Wongkham S,Chen C

更新日期：2013-09-23 00:00:00

abstract：BACKGROUND:The role of chemotherapy in high-risk soft tissue sarcoma is controversial. Though many patients undergo initial curative resection, distant metastasis is a frequent event, resulting in 5-year overall survival rates of only 50-60%. Neo-adjuvant and adjuvant chemotherapy (CTX) has been applied to achieve pre-...

journal_title：BMC cancer

authors： Schmitt T,Lehner B,Kasper B,Bischof M,Roeder F,Dietrich S,Dimitrakopoulou-Strauss A,Strauss LG,Mechtersheimer G,Wuchter P,Ho AD,Egerer G

更新日期：2011-12-07 00:00:00

abstract：BACKGROUND:Breast cancer in women is increasingly frequent, and care is complex, onerous and expensive, all of which lend urgency to improvements in care. Quality measurement is essential to monitor effectiveness and to guide improvements in healthcare. METHODS:Ten databases, including Medline, were searched electroni...

journal_title：BMC cancer

authors： Schachter HM,Mamaladze V,Lewin G,Graham ID,Brouwers M,Sampson M,Morrison A,Zhang L,O'Blenis P,Garritty C

更新日期：2006-12-18 00:00:00

abstract：BACKGROUND:For gastric cancer patients, surgical resection with en-bloc lymphadenectomy is the cornerstone of curative treatment. Open gastrectomy has long been the preferred surgical approach worldwide. However, this procedure is associated with considerable morbidity. Several meta-analyses have shown an advantage in ...

journal_title：BMC cancer

authors： Haverkamp L,Brenkman HJ,Seesing MF,Gisbertz SS,van Berge Henegouwen MI,Luyer MD,Nieuwenhuijzen GA,Wijnhoven BP,van Lanschot JJ,de Steur WO,Hartgrink HH,Stoot JH,Hulsewé KW,Spillenaar Bilgen EJ,Rütter JE,Kouwenhoven EA,van

更新日期：2015-07-29 00:00:00

abstract：BACKGROUND:Solitary plasmacytoma (SP) is a localized neoplastic plasma cell disorder with an annual incidence of less than 450 cases. Given the rarity of this disorder, it is difficult to conduct large-scale population studies. Consequently, very limited information on the disorder is available, making it difficult to ...

journal_title：BMC cancer

authors： Thumallapally N,Meshref A,Mousa M,Terjanian T

更新日期：2017-01-05 00:00:00

abstract：BACKGROUND:Triple-negative (TN) breast cancer, which is defined as being negative for the estrogen receptor (ER), the progesterone receptor (PR), and the human epidermal growth factor receptor 2 (HER-2), represents a subset of breast cancer with different biologic behaviour. We investigated the clinicopathologic charac...

journal_title：BMC cancer

authors： Rhee J,Han SW,Oh DY,Kim JH,Im SA,Han W,Park IA,Noh DY,Bang YJ,Kim TY

更新日期：2008-10-23 00:00:00

abstract：BACKGROUND:IMMUNEPOTENT CRP (ICRP) can be cytotoxic to cancer cell lines. However, its widespread use in cancer patients has been limited by the absence of conclusive data on the molecular mechanism of its action. Here, we evaluated the mechanism of cell death induced by ICRP in HeLa and MCF-7 cells. METHODS:Cell deat...

journal_title：BMC cancer

authors： Martínez-Torres AC,Reyes-Ruiz A,Calvillo-Rodriguez KM,Alvarez-Valadez KM,Uscanga-Palomeque AC,Tamez-Guerra RS,Rodríguez-Padilla C

更新日期：2020-07-13 00:00:00

abstract：BACKGROUND:Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase-derived reactive oxygen species (ROS) not only can promote cancer progression, but also they have recently emerged as mediators of the mucosal immune system. However, the roles and clinical relevance of the collective or individual NADPH oxidase (NO...

journal_title：BMC cancer

authors： Cho SY,Kim S,Son MJ,Kim G,Singh P,Kim HN,Choi HG,Yoo HJ,Ko YB,Lee BS,Eun HS

更新日期：2019-11-09 00:00:00

abstract：BACKGROUND:This study aimed to investigate the clinical utility of serum and histological MMP-9 detection during neoadjuvant chemotherapy (NAC) for triple-negative breast cancer (TNBC). METHODS:A total of 303 TNBC patients who underwent weekly paclitaxel plus carboplatin treatments followed by surgical resection were ...

journal_title：BMC cancer

authors： Wang RX,Chen S,Huang L,Shao ZM

更新日期：2018-09-21 00:00:00

abstract：BACKGROUND:Malignant glioma is a common primary tumor of the central nervous system. Brevican, an abundant extracellular matrix component in the adult brain, plays a critical role in the process of glioma. The mechanisms for the highly invasive behavior of gliomas are still poorly understood. The aim of this study was ...

journal_title：BMC cancer

authors： Lu R,Wu C,Guo L,Liu Y,Mo W,Wang H,Ding J,Wong ET,Yu M

更新日期：2012-12-19 00:00:00

abstract：BACKGROUND:A candidate oncogene GIG47, previously known as a neudesin with a neurotrophic activity, was identified by applying the differential expression analysis method. METHODS:As a first step to understand the molecular role of GIG47, we analyzed the expression profile of GIG47 in multiple human cancers including ...

journal_title：BMC cancer

authors： Han KH,Lee SH,Ha SA,Kim HK,Lee C,Kim DH,Gong KH,Yoo J,Kim S,Kim JW

更新日期：2012-07-02 00:00:00

abstract：BACKGROUND:Various efforts to understand the relationship between biological information and disease have been done using many different types of highthroughput data such as genomics and metabolomics. However, information obtained from previous studies was not satisfactory, implying that new direction of studies is in ...

journal_title：BMC cancer

authors： Jeong J,Seo K,Kim ES

更新日期：2018-11-13 00:00:00

abstract：BACKGROUND:The aim of the present study was to investigate the association between matrix metalloproteinase-9 (MMP-9) expression with BRAF V600E mutation and clinicopathological features, in Iranian papillary thyroid cancer (PTC) patients. METHODS:In total, 90 participants including 60 PTC patients (15 males and 45 fe...

journal_title：BMC cancer

authors： Zarkesh M,Zadeh-Vakili A,Akbarzadeh M,Fanaei SA,Hedayati M,Azizi F

更新日期：2018-12-03 00:00:00

abstract：BACKGROUND:The numerous side effects of chemotherapy in patients with breast cancer are well known. However, the precise effects of chemotherapy on ovarian function in premenopausal women are poorly investigated. The patients are at risk of developing sexual hormone deficiency and impaired fertility. This prospective c...

journal_title：BMC cancer

authors： Wenners A,Grambach J,Koss J,Maass N,Jonat W,Schmutzler A,Mundhenke C

更新日期：2017-09-06 00:00:00

abstract：BACKGROUND:Bevacizumab, a humanized antibody to vascular endothelial growth factor (VEGF), shows clinical activity against human cancer, with its addition to standard chemotherapy having been found to improve outcome in patients with advanced nonsquamous non-small cell lung cancer (NSCLC). However, there have been no e...

journal_title：BMC cancer

authors： Takeda M,Okamoto I,Yamanaka T,Nakagawa K,Nakanishi Y

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Extrahepatic biliary duct cancers (EBDC) are uncommon malignancies characterized by a poor prognosis with high rate of loco-regional recurrence. The purpose of the present study is to assess the feasibility and the potential impact of adjuvant radiotherapy (RT) in a series of patients treated in one institut...

journal_title：BMC cancer

authors： Bonet Beltrán M,Roth AD,Mentha G,Allal AS

更新日期：2011-06-24 00:00:00

abstract：BACKGROUND:Hypoxia is often encountered in solid tumors and known to contribute to aggressive tumor behavior, radiation- and chemotherapy resistance resulting in a poor prognosis for the cancer patient. MicroRNAs (miRNAs) play a role in the regulation of the tumor cell response to hypoxia, however, not much is known ab...

journal_title：BMC cancer

authors： Gits CM,van Kuijk PF,de Rijck JC,Muskens N,Jonkers MB,van IJcken WF,Mathijssen RH,Verweij J,Sleijfer S,Wiemer EA

更新日期：2014-06-13 00:00:00

abstract：BACKGROUND:Hepatocyte carcinoma (HCC) is one of the most common malignancies worldwide. Despite many achievements in diagnosis and treatment, HCC mortality remains high due to the malignant nature of the disease. Novel approaches, especially for targeted therapy, are being extensively explored. Gene therapy is ideal fo...

journal_title：BMC cancer

authors： Liu H,Wei Q,Wang J,Huang X,Li C,Zheng Q,Cao J,Jia Z

更新日期：2015-04-29 00:00:00

abstract：BACKGROUND:Response-guided neoadjuvant chemotherapy (RG-NACT) with magnetic resonance imaging (MRI) is effective in treating oestrogen receptor positive/human epidermal growth factor receptor-2 negative (ER-positive/HER2-negative) breast cancer. We estimated the expected cost-effectiveness and resources required for it...

journal_title：BMC cancer

authors： Miquel-Cases A,Steuten LM,Rigter LS,van Harten WH

更新日期：2016-09-05 00:00:00

abstract：BACKGROUND:The aim of this study was to assess the severity of pain and its impact on the quality of life (QoL) in untreated patients with head and neck squamous cell carcinoma (HNSCC). METHODS:A study group of 127 patients with HNSCC were interviewed before antineoplastic treatment. The severity of pain was measured ...

journal_title：BMC cancer

authors： Oliveira KG,von Zeidler SV,Podestá JR,Sena A,Souza ED,Lenzi J,Bissoli NS,Gouvea SA

更新日期：2014-01-24 00:00:00

abstract：BACKGROUND:Treatment standard for patients with primary glioblastoma (GBM) is combined radiochemotherapy with temozolomide (TMZ). Radiation is delivered up to a total dose of 60 Gy using photons. Using this treatment regimen, overall survival could be extended significantly however, median overall survival is still onl...

journal_title：BMC cancer

authors： Combs SE,Kieser M,Rieken S,Habermehl D,Jäkel O,Haberer T,Nikoghosyan A,Haselmann R,Unterberg A,Wick W,Debus J

更新日期：2010-09-06 00:00:00

abstract：BACKGROUND:Multimodality treatment improves the chance of survival but increases the risk for long-term side effects in young cancer survivors, so-called" Adolescents and Young Adults"(AYAs). Compared to the general population AYAs have a 5 to 15-fold increased risk of cardiovascular morbidity. Thus, improving modifiab...

journal_title：BMC cancer

authors： Quidde J,von Grundherr J,Koch B,Bokemeyer C,Escherich G,Valentini L,Buchholz D,Schilling G,Stein A

更新日期：2016-11-08 00:00:00

abstract：BACKGROUND:Treatment with recombinant human granulocyte-colony stimulating factor (G-CSF) is accepted standard for prevention of chemotherapy-induced neutropenia. RGB-02 (Gedeon Richter) is a proposed biosimilar to pegylated G-CSF (Neulasta®, Amgen) with sustained release properties. This is a randomized, comparative, ...

journal_title：BMC cancer

authors： Kahan Z,Grecea D,Smakal M,Tjulandin S,Bondarenko I,Perjesi L,Illes A,Horvat-Karajz K,Aradi I

更新日期：2019-02-06 00:00:00

abstract：BACKGROUND:Cigarette smoking is an established risk factor for bladder cancer. Epidemiological and biological data suggest that genetic polymorphisms in activating and detoxifying enzymes may play a role in determining an individual's susceptibility to bladder cancer in particular when in combination with specific envi...

journal_title：BMC cancer

authors： McGrath M,Michaud D,De Vivo I

更新日期：2006-10-06 00:00:00

abstract：BACKGROUND:The glycosylphosphatidylinositol-anchored extracellular membrane serine protease prostasin is expressed in normal bladder urothelial cells. Bladder inflammation reduces prostasin expression and a loss of prostasin expression is associated with epithelial-mesenchymal transition (EMT) in human bladder transiti...

journal_title：BMC cancer

authors： Chai AC,Robinson AL,Chai KX,Chen LM

更新日期：2015-12-29 00:00:00

abstract：BACKGROUND:MicroRNA (miR)-200c has been widely reported to be involved in colon cancer progress. However, the mechanisms of miR-200c in regulating tumor metastasis and growth remain to be fully elucidated. This study aimed to investigate the mechanism of miR-200c targets fucosyltransferase 4 (FUT4) on the proliferation...

journal_title：BMC cancer

authors： Cong J,Gong J,Yang C,Xia Z,Zhang H

更新日期：2021-01-04 00:00:00

abstract：BACKGROUND:Male breast cancer (MBC) is rare, accounting for only around 1% of all breast cancers. Most MBCs are hormone-driven. Not only the estrogen receptor (ER), but also other steroid hormone receptors, including the androgen receptor (AR) and progesterone receptor (PgR) are expressed in MBC. AR activation in breas...

journal_title：BMC cancer

authors： Takuwa H,Tsuji W,Shintaku M,Yotsumoto F

更新日期：2018-12-22 00:00:00

abstract：BACKGROUND:Preclinical evidence suggests that aspirin may inhibit lung cancer progression. In a large cohort of lung cancer patients, we investigated whether low-dose aspirin use was associated with a reduction in the risk of lung cancer-specific mortality. METHODS:We identified lung cancer patients from English cance...

journal_title：BMC cancer

authors： Mc Menamin ÚC,Cardwell CR,Hughes CM,Murray LM

更新日期：2015-11-17 00:00:00

abstract：BACKGROUND:In Taiwan, a distinct ethnic group variation in incidence and mortality rates has been suggested for most carcinomas. Our aim is to identify the role of prognostic factors associated with the survival of oral and pharyngeal carcinoma in Taiwan. METHODS:Taiwan Cancer Registry records of 9039 subjects diagnos...

journal_title：BMC cancer

authors： Chen PH,Shieh TY,Ho PS,Tsai CC,Yang YH,Lin YC,Ko MS,Tsai PC,Chiang SL,Tu HP,Ko YC

更新日期：2007-06-15 00:00:00

abstract：BACKGROUND:Whether chronic inflammation increases prostate cancer risk remains unclear. This study investigated whether chronic inflammatory diseases (CID) or anti-inflammatory medication use (AIM) were associated with prostate cancer risk. METHODS:Fifty-five thousand nine hundred thirty-seven cases (all prostate canc...

journal_title：BMC cancer

authors： Beckmann K,Russell B,Josephs D,Garmo H,Haggstrom C,Holmberg L,Stattin P,Van Hemelrijck M,Adolfsson J

更新日期：2019-06-21 00:00:00