Knockout of interleukin-17A protects against sepsis-associated acute kidney injury.

abstract：BACKGROUND:Middle East respiratory syndrome coronavirus (MERS-CoV) has caused several hospital outbreaks, including a major outbreak at King Abdulaziz Medical City, a 940-bed tertiary-care hospital in Riyadh, Saudi Arabia (August-September 2015). To learn from our experience, we described the critical care response to ...

journal_title：Annals of intensive care

authors： Al-Dorzi HM,Aldawood AS,Khan R,Baharoon S,Alchin JD,Matroud AA,Al Johany SM,Balkhy HH,Arabi YM

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Aneurysmal subarachnoid hemorrhage (SAH) is a serious condition associated with high mortality rates and long-term disability. We investigated the impact of fluid balance on neurologic outcome after adjustment for possible confounders related to intensive care therapy and extra-cerebral organ failure during ...

journal_title：Annals of intensive care

authors： Sakr Y,Dünisch P,Santos C,Matthes L,Zeidan M,Reinhart K,Kalff R,Ewald C

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Despite improvements in intermittent hemodialysis management, intradialytic hemodynamic instability (IHI) remains a common issue that could account for increased mortality and delayed renal recovery. However, predictive factors of IHI remain poorly explored. The objective of this study was to evaluate the re...

journal_title：Annals of intensive care

authors： Bigé N,Lavillegrand JR,Dang J,Attias P,Deryckere S,Joffre J,Dubée V,Preda G,Dumas G,Hariri G,Pichereau C,Baudel JL,Guidet B,Maury E,Boelle PY,Ait-Oufella H

更新日期：2020-04-22 00:00:00

abstract：: Critically ill adult patients often require multiple examinations in the hospital and need transport from one department to another, or even between hospitals. However, to date, no guidelines exist regarding optimum practices for transport of these fragile patients. We present recommendations for intrahospital transp...

journal_title：Annals of intensive care

authors： Quenot JP,Milési C,Cravoisy A,Capellier G,Mimoz O,Fourcade O,Gueugniaud PY

更新日期：2012-02-03 00:00:00

abstract：: Erythropoietin (EPO) is the major hormone stimulating the production and differentiation of red blood cells. EPO is used widely for treating anemia of critical illness or anemia induced by chemotherapy. EPO at pharmacological doses is used in this setting to raise hemoglobin levels (by preventing the apoptosis of ery...

journal_title：Annals of intensive care

authors： Patel NS,Collino M,Yaqoob MM,Thiemermann C

更新日期：2011-09-23 00:00:00

abstract：BACKGROUND:Despite advances in supportive care, moderate-severe acute respiratory distress syndrome (ARDS) is associated with high mortality rates, and novel therapies to treat this condition are needed. Compelling pre-clinical data from mouse, rat, sheep and ex vivo perfused human lung models support the use of human ...

journal_title：Annals of intensive care

authors： Liu KD,Wilson JG,Zhuo H,Caballero L,McMillan ML,Fang X,Cosgrove K,Calfee CS,Lee JW,Kangelaris KN,Gotts JE,Rogers AJ,Levitt JE,Wiener-Kronish JP,Delucchi KL,Leavitt AD,McKenna DH,Thompson BT,Matthay MA

更新日期：2014-07-03 00:00:00

abstract：: Multiple experimental and human trials have shown that microcirculatory alterations are frequent in sepsis. In this review, we discuss the characteristics of these alterations, the various mechanisms potentially involved, and the implications for therapy. Sepsis-induced microvascular alterations are characterized by ...

journal_title：Annals of intensive care

authors： De Backer D,Donadello K,Taccone FS,Ospina-Tascon G,Salgado D,Vincent JL

更新日期：2011-07-19 00:00:00

abstract：BACKGROUND:Hyponatremia occurring as a result of the syndrome of inappropriate antidiuretic hormone secretion (SIADH) or cerebral salt wasting syndrome is a common complication in patients with subarachnoid hemorrhage (SAH). The efficacy and safety of urea as treatment for SIADH-induced hyponatremia has not been report...

journal_title：Annals of intensive care

authors： Pierrakos C,Taccone FS,Decaux G,Vincent JL,Brimioulle S

更新日期：2012-05-30 00:00:00

abstract：BACKGROUND:Noninvasive ventilation (NIV) is the first-line treatment of adult patients with exacerbations of cystic fibrosis (CF). High-flow nasal oxygen therapy (HFNT) might benefit patients with hypoxemia and can reduce physiological dead space. We hypothesized that HFNT and NIV would similarly reduce work of breathi...

journal_title：Annals of intensive care

authors： Sklar MC,Dres M,Rittayamai N,West B,Grieco DL,Telias I,Junhasavasdikul D,Rauseo M,Pham T,Madotto F,Campbell C,Tullis E,Brochard L

更新日期：2018-09-05 00:00:00

abstract：INTRODUCTION:About 30% of patients with Guillain-Barré syndrome become ventilator dependent, of whom roughly 75% develop pneumonia. This trial aimed at assessing the impact of early mechanical ventilation (EMV) on pneumonia occurrence in GBS patients. We hypothesize that EMV will reduce the incidence of pneumonia. MET...

journal_title：Annals of intensive care

authors： Melone MA,Heming N,Meng P,Mompoint D,Aboab J,Clair B,Salomon J,Sharshar T,Orlikowski D,Chevret S,Annane D

更新日期：2020-09-30 00:00:00

abstract：BACKGROUND:Ultrafast cooling by total liquid ventilation (TLV) provides potent cardio- and neuroprotection after experimental cardiac arrest. However, this was evaluated in animals with no initial lung injury, whereas out-of-hospital cardiac arrest is frequently associated with early-onset pneumonia, which may lead to ...

journal_title：Annals of intensive care

authors： Rambaud J,Lidouren F,Sage M,Kohlhauer M,Nadeau M,Fortin-Pellerin É,Micheau P,Zilberstein L,Mongardon N,Ricard JD,Terada M,Bruneval P,Berdeaux A,Ghaleh B,Walti H,Tissier R

更新日期：2018-05-02 00:00:00

abstract：BACKGROUND:Acute kidney injury (AKI) occurs in up to 50% of all critically ill patients and hemodynamic abnormalities are assumed to contribute, but their nature and share is still unclear. We explored the associations between hemodynamic variables, including cardiac index and right ventricular function, and the occurr...

journal_title：Annals of intensive care

authors： Wiersema R,Koeze J,Hiemstra B,Pettilä V,Perner A,Keus F,van der Horst ICC,SICS Study Group.

更新日期：2019-03-13 00:00:00

abstract：BACKGROUND:The choice of empirical antimicrobial therapy for pneumonia in intensive care unit (ICU) is a challenge, since pneumonia is often related to multidrug-resistant pathogens, particularly extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-E). To prevent the overuse of broad-spectrum antimicrobial ...

journal_title：Annals of intensive care

authors： Carbonne H,Le Dorze M,Bourrel AS,Poupet H,Poyart C,Cambau E,Mira JP,Charpentier J,Amarsy R

更新日期：2017-12-01 00:00:00

abstract：INTRODUCTION:Capillary leak in critically ill patients leads to interstitial edema. Fluid overload is independently associated with poor prognosis. Bedside measurement of intra-abdominal pressure (IAP), extravascular lung water index (EVLWI), fluid balance, and capillary leak index (CLI) may provide a valuable prognost...

journal_title：Annals of intensive care

authors： Cordemans C,De Laet I,Van Regenmortel N,Schoonheydt K,Dits H,Huber W,Malbrain ML

更新日期：2012-07-05 00:00:00

abstract：BACKGROUND:Optimal sedation and analgesia is a challenge in paediatric intensive care units (PICU) because of difficulties in scoring systems and specific metabolism inducing tolerance and withdrawal. Excessive sedation is associated with prolonged mechanical ventilation and hospitalisation. Adult and paediatric data s...

journal_title：Annals of intensive care

authors： Dreyfus L,Javouhey E,Denis A,Touzet S,Bordet F

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:The echocardiography working group of the European Society of Intensive Care Medicine recognized the need to provide structured guidance for future CCE research methodology and reporting based on a systematic appraisal of the current literature. Here is reported this systematic appraisal. METHODS:We conduct...

journal_title：Annals of intensive care

authors： Huang S,Sanfilippo F,Herpain A,Balik M,Chew M,Clau-Terré F,Corredor C,De Backer D,Fletcher N,Geri G,Mekontso-Dessap A,McLean A,Morelli A,Orde S,Petrinic T,Slama M,van der Horst ICC,Vignon P,Mayo P,Vieillard-Baron A

更新日期：2020-04-25 00:00:00

abstract：BACKGROUND:The initial management of a trauma patient is a critical and demanding period. The use of extended focused assessment sonography for trauma (eFAST) has become more prevalent in trauma rooms, raising questions about the real "added value" of chest X-rays (CXRs) and pelvic X-rays (PXR), particularly in haemody...

journal_title：Annals of intensive care

authors： Hamada SR,Delhaye N,Kerever S,Harrois A,Duranteau J

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:In randomised controlled trials, procalcitonin (PCT)-guided antibiotic treatment has been proven to significantly reduce length of antibiotic therapy in intensive care unit (ICU) patients. However, concern was raised on low protocol adherence and high rates of overruling, and thus the value of PCT-guided tre...

journal_title：Annals of intensive care

authors： Hohn A,Balfer N,Heising B,Hertel S,Wiemer JC,Hochreiter M,Schröder S

更新日期：2018-06-04 00:00:00

abstract：:Animal experiments are widely used in preclinical medical research with the goal of disease modeling and exploration of novel therapeutic approaches. In the context of sepsis and septic shock, the translation into clinical practice has been disappointing. Classical animal models of septic shock usually involve one-sex...

journal_title：Annals of intensive care

authors： Guillon A,Preau S,Aboab J,Azabou E,Jung B,Silva S,Textoris J,Uhel F,Vodovar D,Zafrani L,de Prost N,Radermacher P,Translational Research Committee of the French Intensive Care Society (Société de Réanimation de Langue Française).

更新日期：2019-06-10 00:00:00

abstract：:In the past, the only treatment of acute exacerbations of obstructive diseases with hypercapnic respiratory failure refractory to medical treatment was invasive mechanical ventilation (IMV). Considerable technical improvements transformed extracorporeal techniques for carbon dioxide removal in an attractive option to ...

journal_title：Annals of intensive care

authors： Morales-Quinteros L,Del Sorbo L,Artigas A

更新日期：2019-07-02 00:00:00

abstract：BACKGROUND:Endotoxins can induce an excessive inflammatory response and result in microcirculatory dysfunction. Polymyxin-B hemoperfusion (PMX-HP) has been recognized to effectively remove endotoxins in patients with sepsis and septic shock, and a rat sepsis model revealed that PMX-HP treatment can maintain a better mi...

journal_title：Annals of intensive care

authors： Chen SH,Chan WS,Liu CM,Chiu CT,Chao A,Wu VC,Sheng WH,Lai CH,Wang MJ,Yeh YC

更新日期：2020-06-12 00:00:00

abstract：BACKGROUND:Pendelluft, the movement of gas within different lung regions, is present in animal models of assisted mechanical ventilation and associated with lung overstretching. Due to rebreathing of CO2 as compared to fresh gas, pendelluft might reduce ventilatory efficiency possibly exacerbating patient's respiratory...

journal_title：Annals of intensive care

authors： Coppadoro A,Grassi A,Giovannoni C,Rabboni F,Eronia N,Bronco A,Foti G,Fumagalli R,Bellani G

更新日期：2020-04-07 00:00:00

abstract：:The death of a loved one is often an ordeal and a tragedy for those who witness it, as death is not merely the end of a life, but also the end of an existence, the loss of a unique individual who is special and irreplaceable. In some situations, end-of-life signs, such as agonal gasps, can be an almost unbearable "sig...

journal_title：Annals of intensive care

authors： Daubin C,Haddad L,Folscheid D,Boyer A,Chalumeau-Lemoine L,Guisset O,Hubert P,Pillot J,Robert R,Dreyfuss D

更新日期：2014-07-08 00:00:00

abstract：BACKGROUND:Among intensive care unit (ICU) patients with acute respiratory distress syndrome (ARDS), apart from acute cor pulmonale (ACP), the frequency and prognostic impact of basic critical care echocardiography (BCCE) abnormalities are not well defined. METHODS:Observational study of patients with ARDS, admitted f...

journal_title：Annals of intensive care

authors： See KC,Ng J,Siow WT,Ong V,Phua J

更新日期：2017-12-19 00:00:00

abstract：Introduction:Acute respiratory failure is the main reason for admission to the intensive care unit (ICU) in HIV-infected adults. There is little data about the epidemiology of respiratory viruses in this population. Methods:HIV-infected adults admitted to two intensive care units over a 6-year period for an acute resp...

journal_title：Annals of intensive care

authors： Elabbadi A,Pichon J,Visseaux B,Schnuriger A,Bouadma L,Philippot Q,Patrier J,Labbé V,Ruckly S,Fartoukh M,Timsit JF,Voiriot G

更新日期：2020-09-14 00:00:00

abstract：BACKGROUND:Lactate is a robust prognostic marker for the outcome of critically ill patients. Several small studies reported that metformin users have higher lactate levels at ICU admission without a concomitant increase in mortality. However, this has not been investigated in a larger cohort. We aimed to determine whet...

journal_title：Annals of intensive care

authors： Posma RA,Frøslev T,Jespersen B,van der Horst ICC,Touw DJ,Thomsen RW,Nijsten MW,Christiansen CF

更新日期：2020-03-26 00:00:00

abstract：UNLABELLED: BACKGROUND:A history of prolonged and excessive consumption of alcohol increases the risk for infections. The goal of this study was to investigate circulating white blood cells (WBC) differentiated by flow cytometry and neutrophil CD64 expression in excessive alcohol drinkers versus abstinent or moderate ...

journal_title：Annals of intensive care

authors： Gacouin A,Roussel M,Gros A,Sauvadet E,Uhel F,Chimot L,Marque S,Camus C,Fest T,Le Tulzo Y

更新日期：2012-12-31 00:00:00

abstract：BACKGROUND:While the process of sepsis-induced immunosuppression is now well described in adults, very little information is available on immune functions in pediatric sepsis. The current study investigated this in children with septic shock by performing immunomonitoring, including both innate (monocyte human leukocyt...

journal_title：Annals of intensive care

authors： Remy S,Kolev-Descamps K,Gossez M,Venet F,Demaret J,Javouhey E,Monneret G

更新日期：2018-03-13 00:00:00

abstract：: Cancer is a leading cause of death in children. In the past decades, there has been a marked increase in overall survival of children with cancer. However, children whose treatment includes hematopoietic stem cell transplantation still represent a subpopulation with a higher risk of mortality. These improvements in m...

journal_title：Annals of intensive care

authors： Demaret P,Pettersen G,Hubert P,Teira P,Emeriaud G

更新日期：2012-06-12 00:00:00

abstract：BACKGROUND:High-frequency oscillatory ventilation (HFOV) is a common but unproven management strategy in paediatric critical care. Oscillator settings have been traditionally guided by patient age and/or weight rather than by lung mechanics, thereby potentially negating any beneficial effects. We have adopted an open-l...

journal_title：Annals of intensive care

authors： de Jager P,Kamp T,Dijkstra SK,Burgerhof JGM,Markhorst DG,Curley MAQ,Cheifetz IM,Kneyber MCJ

更新日期：2019-01-18 00:00:00